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The map label for this gene is coaA [H]

Identifier: 119870238

GI number: 119870238

Start: 4436483

End: 4437421

Strand: Direct

Name: coaA [H]

Synonym: Mkms_4208

Alternate gene names: 119870238

Gene position: 4436483-4437421 (Clockwise)

Preceding gene: 119870229

Following gene: 119870243

Centisome position: 77.33

GC content: 66.35

Gene sequence:

>939_bases
ATGGCGCGGCTGAGCGAACCGAGCCCCTACGTGGAGTTCGACCGCACCCAGTGGCGTGCGCTCCGGATGTCTACGCCGCT
GAAACTGACCGAGGACGAGCTCAAGAAGCTCCGCGGTCTCGGCGAGAAACTCGACCTCCTCGAGGTCGAGGAGGTCTACC
TCCCGCTGGCCCGGCTGATCCACCTGCAGGTGGCCGCCCGGCAACGGTTGTTCGCCGCGACGTCGGAGTTCCTCGGCGAA
CCGCAGCAGAACCCCGACCGGCCGGTCCCGTTCATCATCGGCGTCGCGGGCAGTGTGGCCGTCGGCAAGTCCACCACCGC
TCGTGTGCTGCAGGCGCTGTTGGCGCGGTGGGGTAACCACGCCCGCGTCGACCTGGTCACCACCGACGGGTTCCTCTACC
CGAATGCGGAGTTGGGCCGCCGGAACATCATGCACCGCAAGGGTTTTCCGGAGAGCTATGACCGCAGGGCGTTGATGCGC
TTCGTCACCGCGGTGAAGTCCGGCGCCGATTACGCCTGCGCGCCGGTGTATTCACACCTGCTCTACGACATCGTGCCCGG
CGAGAAGCAGGTGATCCGTCATCCCGACATCCTGATCCTCGAGGGTCTCAACGTGCTGCAGACCGGCCCGGCGCTGATGG
TCTCGGACCTGTTCGACTTCTCGGTCTACGTCGACGCGCGCCTCGAGGACATCGAGGGCTGGTACATCTCGCGGTTCCTG
ACGATGCGGTCGACGGCGTTCGCCGATCCGGCGTCGCACTTCCATCACTACGCGACGCTGACCGACGAACAGGCCGTCTT
CGCTGCCCGCGACATCTGGCATTCGATCAACCGGCCGAACCTGATCGAGAACATCCTGCCGACCCGGCCGCGGGCGACGC
TGGTGCTGCGCAAGGACGCCGACCACGCCATCAACCGGTTGCGCCTGCGCAAGCTCTGA

Upstream 100 bases:

>100_bases
AGCAGATATTCGCGGATCAGGGTGTCGGGCTCCATGCCCGCAACGCTAATCTCCTCGCCCCAGGCGTTCACCCCGGAGCC
CGTACTGCAAGACTGATCCC

Downstream 100 bases:

>100_bases
CTCACCGCCCCCCGCGAGCAGACGCAAATGTCCCCGACAGCTCGGCGTGTCGGGGACATTTGTGTCTGCTCGGCAAGTCA
GAGGCGGCGCCAGCCCACGT

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELKKLRGLGEKLDLLEVEEVYLPLARLIHLQVAARQRLFAATSEFLGE
PQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWGNHARVDLVTTDGFLYPNAELGRRNIMHRKGFPESYDRRALMR
FVTAVKSGADYACAPVYSHLLYDIVPGEKQVIRHPDILILEGLNVLQTGPALMVSDLFDFSVYVDARLEDIEGWYISRFL
TMRSTAFADPASHFHHYATLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDADHAINRLRLRKL

Sequences:

>Translated_312_residues
MARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELKKLRGLGEKLDLLEVEEVYLPLARLIHLQVAARQRLFAATSEFLGE
PQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWGNHARVDLVTTDGFLYPNAELGRRNIMHRKGFPESYDRRALMR
FVTAVKSGADYACAPVYSHLLYDIVPGEKQVIRHPDILILEGLNVLQTGPALMVSDLFDFSVYVDARLEDIEGWYISRFL
TMRSTAFADPASHFHHYATLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDADHAINRLRLRKL
>Mature_311_residues
ARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELKKLRGLGEKLDLLEVEEVYLPLARLIHLQVAARQRLFAATSEFLGEP
QQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWGNHARVDLVTTDGFLYPNAELGRRNIMHRKGFPESYDRRALMRF
VTAVKSGADYACAPVYSHLLYDIVPGEKQVIRHPDILILEGLNVLQTGPALMVSDLFDFSVYVDARLEDIEGWYISRFLT
MRSTAFADPASHFHHYATLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDADHAINRLRLRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=311, Percent_Identity=53.6977491961415, Blast_Score=341, Evalue=4e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35477; Mature: 35346

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELKKLRGLGEKLDLLEVEEVYLPLARLI
CCCCCCCCCCEEECCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVAARQRLFAATSEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWGNH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCC
ARVDLVTTDGFLYPNAELGRRNIMHRKGFPESYDRRALMRFVTAVKSGADYACAPVYSHL
CEEEEEEECCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LYDIVPGEKQVIRHPDILILEGLNVLQTGPALMVSDLFDFSVYVDARLEDIEGWYISRFL
HHHCCCCCHHHHCCCCEEEECCCHHHHCCCHHHHHHHHHEEEEEECCHHHCCHHHHHHHH
TMRSTAFADPASHFHHYATLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDA
HHHHHHCCCHHHHHHHHHEECCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCH
DHAINRLRLRKL
HHHHHHHHHHCC
>Mature Secondary Structure 
ARLSEPSPYVEFDRTQWRALRMSTPLKLTEDELKKLRGLGEKLDLLEVEEVYLPLARLI
CCCCCCCCCEEECCCHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVAARQRLFAATSEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWGNH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCC
ARVDLVTTDGFLYPNAELGRRNIMHRKGFPESYDRRALMRFVTAVKSGADYACAPVYSHL
CEEEEEEECCEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
LYDIVPGEKQVIRHPDILILEGLNVLQTGPALMVSDLFDFSVYVDARLEDIEGWYISRFL
HHHCCCCCHHHHCCCCEEEECCCHHHHCCCHHHHHHHHHEEEEEECCHHHCCHHHHHHHH
TMRSTAFADPASHFHHYATLTDEQAVFAARDIWHSINRPNLIENILPTRPRATLVLRKDA
HHHHHHCCCHHHHHHHHHEECCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCH
DHAINRLRLRKL
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA