| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is fabG [H]
Identifier: 119870222
GI number: 119870222
Start: 4418692
End: 4419516
Strand: Direct
Name: fabG [H]
Synonym: Mkms_4192
Alternate gene names: 119870222
Gene position: 4418692-4419516 (Clockwise)
Preceding gene: 119870221
Following gene: 119870223
Centisome position: 77.02
GC content: 72.12
Gene sequence:
>825_bases ATGGACTTCGCGGGCAGACAGGCGATCGTCACCGGCGCCGGTTCGGGCATCGGCGCCGCTCTGTGCCGGGCACTGGTGGC GGCCGGGGCCGAGGTGTTGTGCACCGACATCGACGCCGACGCCGCCGAGGCGACCGCGCGTGGGCTCGGCGCCCGCTGGT CACCCCTGGACGTCACCGACGCCGCCGCGGTGCAGCGGGCCGTCGACGAGGTGGTGGCGCGCGCCGGTCGACTGGACCTG ATGTTCAACAACGCGGGCATCTCCTGGGGCGGTGACACCGAACTGCTGACCCTCGACCAGTGGAACGCGATCATCGACAT CAACATCCGCGGTGTGGTGCACGGAGTCGCCGCGGCGTACCCCCAGATGATCCGCCAGGGGCACGGCCACATCGTCAACA CCGCCTCGATGGCGGGCCTCACCGCGGCGGGCCTGATCACCAGCTATGTGATGACCAAACACGCGGTCGTCGGCCTGTCG CTGGCGCTGCGCTCGGAGGCCGTCGCACACGGTGTGGGGGTGCTCGCCGTCTGCCCGGCCGCGGTCGAGACGCCGATCCT CGACAAGGGCGCCGTCGGCGGGTTCGTCGGTCGCGATTATTACCTGCAGGGCCAGCGGGTCAAGGCCCCTTACGACGCCG ACCGGCTGGCGCGCGACACCCTGCGCGCCGTGCAGCGCAACAAGGCCGTGCTGGTCAAACCCCGGCAGGCCCACGCCGCA TGGGTTTTCGCGCGGCTCGCGCCCGGGCTGATGCAGCGGATGGCCGCGCGGTTCGTCGCCGAACAGCGGGCCGGGCAGCG GGCGCAGACCGTCGGCACCGGGTAG
Upstream 100 bases:
>100_bases CTCGTGGATGACCGGGGAGGTACTCGACCTCAACGGCGGGGCCCACCTCAAGAGGTATCCCGACATCCTCAGCCACGTCA TGAAACTCGCGGGGGCATAG
Downstream 100 bases:
>100_bases ACCGCGTGTCCGACGACGTGTCCGGTGATGTGGAAACCGGTTTCACCACCACCCAGAAGCGTGCGCTCAGCGTGGTCACC TTGCTGGCCGTGGCGTTCGG
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 274; Mature: 274
Protein sequence:
>274_residues MDFAGRQAIVTGAGSGIGAALCRALVAAGAEVLCTDIDADAAEATARGLGARWSPLDVTDAAAVQRAVDEVVARAGRLDL MFNNAGISWGGDTELLTLDQWNAIIDINIRGVVHGVAAAYPQMIRQGHGHIVNTASMAGLTAAGLITSYVMTKHAVVGLS LALRSEAVAHGVGVLAVCPAAVETPILDKGAVGGFVGRDYYLQGQRVKAPYDADRLARDTLRAVQRNKAVLVKPRQAHAA WVFARLAPGLMQRMAARFVAEQRAGQRAQTVGTG
Sequences:
>Translated_274_residues MDFAGRQAIVTGAGSGIGAALCRALVAAGAEVLCTDIDADAAEATARGLGARWSPLDVTDAAAVQRAVDEVVARAGRLDL MFNNAGISWGGDTELLTLDQWNAIIDINIRGVVHGVAAAYPQMIRQGHGHIVNTASMAGLTAAGLITSYVMTKHAVVGLS LALRSEAVAHGVGVLAVCPAAVETPILDKGAVGGFVGRDYYLQGQRVKAPYDADRLARDTLRAVQRNKAVLVKPRQAHAA WVFARLAPGLMQRMAARFVAEQRAGQRAQTVGTG >Mature_274_residues MDFAGRQAIVTGAGSGIGAALCRALVAAGAEVLCTDIDADAAEATARGLGARWSPLDVTDAAAVQRAVDEVVARAGRLDL MFNNAGISWGGDTELLTLDQWNAIIDINIRGVVHGVAAAYPQMIRQGHGHIVNTASMAGLTAAGLITSYVMTKHAVVGLS LALRSEAVAHGVGVLAVCPAAVETPILDKGAVGGFVGRDYYLQGQRVKAPYDADRLARDTLRAVQRNKAVLVKPRQAHAA WVFARLAPGLMQRMAARFVAEQRAGQRAQTVGTG
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=32, Blast_Score=91, Evalue=9e-19, Organism=Homo sapiens, GI20149619, Length=272, Percent_Identity=26.4705882352941, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI210032110, Length=261, Percent_Identity=26.4367816091954, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI66933014, Length=187, Percent_Identity=30.4812834224599, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=29.3814432989691, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI142976729, Length=279, Percent_Identity=24.3727598566308, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI4758504, Length=197, Percent_Identity=30.4568527918782, Blast_Score=78, Evalue=7e-15, Organism=Homo sapiens, GI224922801, Length=170, Percent_Identity=30.5882352941176, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI40807363, Length=199, Percent_Identity=28.1407035175879, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI22507405, Length=232, Percent_Identity=26.2931034482759, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI15277342, Length=196, Percent_Identity=31.1224489795918, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI59889578, Length=169, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI32483357, Length=188, Percent_Identity=26.5957446808511, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI83715985, Length=173, Percent_Identity=31.2138728323699, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI150247226, Length=193, Percent_Identity=32.6424870466321, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI109715829, Length=193, Percent_Identity=31.6062176165803, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI4504503, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=190, Percent_Identity=33.6842105263158, Blast_Score=104, Evalue=5e-24, Organism=Escherichia coli, GI87082100, Length=189, Percent_Identity=35.4497354497354, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1788459, Length=186, Percent_Identity=31.7204301075269, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1786812, Length=186, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=27.7486910994764, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI87082160, Length=193, Percent_Identity=29.0155440414508, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1789208, Length=189, Percent_Identity=28.042328042328, Blast_Score=78, Evalue=6e-16, Organism=Escherichia coli, GI1787820, Length=204, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367365, Length=183, Percent_Identity=30.6010928961749, Blast_Score=66, Evalue=3e-12, Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=29.1891891891892, Blast_Score=64, Evalue=2e-11, Organism=Escherichia coli, GI1787905, Length=140, Percent_Identity=31.4285714285714, Blast_Score=62, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17508895, Length=270, Percent_Identity=27.7777777777778, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17564282, Length=273, Percent_Identity=25.2747252747253, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=27.6923076923077, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=28.3505154639175, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17555706, Length=197, Percent_Identity=29.9492385786802, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI25147288, Length=195, Percent_Identity=33.8461538461538, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17538182, Length=195, Percent_Identity=29.2307692307692, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562906, Length=195, Percent_Identity=31.7948717948718, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562908, Length=195, Percent_Identity=31.2820512820513, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17560676, Length=185, Percent_Identity=27.5675675675676, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17568967, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17567345, Length=192, Percent_Identity=26.0416666666667, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=29.8969072164948, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=27.6595744680851, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17560332, Length=223, Percent_Identity=26.457399103139, Blast_Score=69, Evalue=4e-12, Organism=Caenorhabditis elegans, GI115534660, Length=193, Percent_Identity=27.4611398963731, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI193204405, Length=195, Percent_Identity=29.7435897435897, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17544670, Length=202, Percent_Identity=26.7326732673267, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71982365, Length=212, Percent_Identity=27.3584905660377, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17551412, Length=197, Percent_Identity=27.4111675126904, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17563726, Length=202, Percent_Identity=29.2079207920792, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17536651, Length=228, Percent_Identity=26.7543859649123, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=28.7179487179487, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=193, Percent_Identity=25.9067357512953, Blast_Score=78, Evalue=2e-15, Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=32.4742268041237, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI21358495, Length=277, Percent_Identity=25.9927797833935, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24644339, Length=200, Percent_Identity=29.5, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI23397609, Length=190, Percent_Identity=33.1578947368421, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI116007236, Length=196, Percent_Identity=31.1224489795918, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24639444, Length=192, Percent_Identity=31.7708333333333, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI281364494, Length=203, Percent_Identity=32.0197044334975, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI116007238, Length=173, Percent_Identity=32.3699421965318, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI21357041, Length=196, Percent_Identity=29.0816326530612, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI21355631, Length=271, Percent_Identity=24.3542435424354, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=27.4111675126904, Blast_Score=74, Evalue=8e-14, Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=27.4111675126904, Blast_Score=74, Evalue=9e-14, Organism=Drosophila melanogaster, GI281364892, Length=171, Percent_Identity=29.2397660818713, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI17737361, Length=195, Percent_Identity=29.7435897435897, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI21355319, Length=193, Percent_Identity=26.4248704663212, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI221331216, Length=198, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=9e-13, Organism=Drosophila melanogaster, GI24640442, Length=193, Percent_Identity=29.5336787564767, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24643142, Length=183, Percent_Identity=32.2404371584699, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=26.6666666666667, Blast_Score=68, Evalue=6e-12, Organism=Drosophila melanogaster, GI116007234, Length=201, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24663911, Length=205, Percent_Identity=31.7073170731707, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28571387, Length=203, Percent_Identity=29.5566502463054, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24648693, Length=210, Percent_Identity=29.0476190476191, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI21355889, Length=210, Percent_Identity=29.0476190476191, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=30.6532663316583, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24581726, Length=259, Percent_Identity=25.0965250965251, Blast_Score=65, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 28557; Mature: 28557
Theoretical pI: Translated: 9.21; Mature: 9.21
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 3.6 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.6 %Met (Mature Protein) 3.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDFAGRQAIVTGAGSGIGAALCRALVAAGAEVLCTDIDADAAEATARGLGARWSPLDVTD CCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCHH AAAVQRAVDEVVARAGRLDLMFNNAGISWGGDTELLTLDQWNAIIDINIRGVVHGVAAAY HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEEEEHHHHHHHHHHH PQMIRQGHGHIVNTASMAGLTAAGLITSYVMTKHAVVGLSLALRSEAVAHGVGVLAVCPA HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCH AVETPILDKGAVGGFVGRDYYLQGQRVKAPYDADRLARDTLRAVQRNKAVLVKPRQAHAA HHCCCCCCCCCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCHHHHH WVFARLAPGLMQRMAARFVAEQRAGQRAQTVGTG HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC >Mature Secondary Structure MDFAGRQAIVTGAGSGIGAALCRALVAAGAEVLCTDIDADAAEATARGLGARWSPLDVTD CCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCHH AAAVQRAVDEVVARAGRLDLMFNNAGISWGGDTELLTLDQWNAIIDINIRGVVHGVAAAY HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCEEEEEEEHHHHHHHHHHH PQMIRQGHGHIVNTASMAGLTAAGLITSYVMTKHAVVGLSLALRSEAVAHGVGVLAVCPA HHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCH AVETPILDKGAVGGFVGRDYYLQGQRVKAPYDADRLARDTLRAVQRNKAVLVKPRQAHAA HHCCCCCCCCCCCCCCCCCEEECCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCHHHHH WVFARLAPGLMQRMAARFVAEQRAGQRAQTVGTG HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]