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The map label for this gene is xseA [H]

Identifier: 119870213

GI number: 119870213

Start: 4410506

End: 4411741

Strand: Direct

Name: xseA [H]

Synonym: Mkms_4183

Alternate gene names: 119870213

Gene position: 4410506-4411741 (Clockwise)

Preceding gene: 119870212

Following gene: 119870214

Centisome position: 76.88

GC content: 71.36

Gene sequence:

>1236_bases
GTGACCACCCCGGCCGACGACCAGGGCAAATCCCCTGAGAATCCCTGGCCGGTCCGGGCTGTGGCCACCCGTGTCGCCAA
GTACATCGACCGGCTCGGCATGGTGTGGATCGAGGGCCAGCTGACCGAGCTCAAGATCCGCCAGACGACGGCCTGGATGG
TTCTGCGCGATCCGGCCGCCGACATGTCGCTGTCGGTGAGCTGCCCGCGCGACCTCGTCGCGAACGCGCCGGTGCCGCTG
TCGGAGGGCACCCAGGTCATCGTGCTGGGCAAACCGCAGTTCTACACCCGCAACGGCTCGTTCAGCCTGCGGATCAGCGA
GATCCGCGCGGTCGGCATCGGCGAACTGCTGGCCCGCATCGACCGCCTGCGTCGGCTGCTCGACGCCGAGGGCCTGTTCG
ATCCCCGGCTCAAACGGCCCATCCCGTTCCTGCCCGGCACGATCGGCCTGATCACCGGCCGCGCCAGCCATGCCGAACGG
GACGTGATGACCGTCGCGGCCAACCGGTGGCCCGCGGTCCGCTTCGCCGTCCGCAACACCATCGTGCAGGGCCCCAACGC
GGTGCCGCAGATCGTCGGCGCGCTTCGCGAACTCGACCGCGACCCCGGTGTGGACGTCATCGTGCTGGCTCGGGGCGGCG
GCAGCGTCGAGGATCTGCTGCCGTTCTCCGACGAGACGCTGTGCCGGGAGATCGCGAGTTGCACCACCCCGGTGGTCAGC
GCGGTCGGCCACGAACCGGACAACCCGCTGTGCGACCTGGTCGCCGACCTGCGCGCGGCCACCCCGACCGACGCGGCCAA
ACGCGTCGTACCCGACGCCGCGGCCGAACAGGCGTTCGTCACCGACCTGCGCCGGCGCAGCGCCCGCGCGTTGCGCCAGT
GGGTGCACCGCGAACAGCACCACCTCGACCAGTTGCGCAGCCGACCGGTGCTGGCCCGTCCGCTGCAGGCGATCGATGCG
CGCGCCGACGAGGTGCACCGCGCCGTGGCCGCGGCCCGTCGCGACGTGCGCCGGATGGTGACGGTGGAATCCGAACGCGT
GGGCCATCTGTCCGCCCGGCTGACGACACTCGGTCCGGCCGCCACACTCGCGCGCGGCTACGCGGTCGTACAGACCATGC
CCGATACGAACGTTCTGCGGACGACTGCCGATGCGCCGGCGGGTACGCACCTGCGCATCCGGGTGGCCGACGGCGCGATC
ACCGCGGTGAGTGAGGGGACCGATGAAGCCCATTAG

Upstream 100 bases:

>100_bases
TCGACGACCTCGAGGCGCTGCTCGCCTATGAGGGCGCCACCCGGTCACGCGCGCCGTTCCAGACCCTGCTGGCGAACCGG
ATCACCCGCGCCACCGCGAA

Downstream 100 bases:

>100_bases
TGAGATGGGGTACGAAGAGGCGCGCGACGAACTGATCGCCGTCGTGCAGCAGCTCGAACAGGGCGGTCTCGATCTGGATG
CGTCGCTCAAGTTGTGGGAA

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTTPADDQGKSPENPWPVRAVATRVAKYIDRLGMVWIEGQLTELKIRQTTAWMVLRDPAADMSLSVSCPRDLVANAPVPL
SEGTQVIVLGKPQFYTRNGSFSLRISEIRAVGIGELLARIDRLRRLLDAEGLFDPRLKRPIPFLPGTIGLITGRASHAER
DVMTVAANRWPAVRFAVRNTIVQGPNAVPQIVGALRELDRDPGVDVIVLARGGGSVEDLLPFSDETLCREIASCTTPVVS
AVGHEPDNPLCDLVADLRAATPTDAAKRVVPDAAAEQAFVTDLRRRSARALRQWVHREQHHLDQLRSRPVLARPLQAIDA
RADEVHRAVAAARRDVRRMVTVESERVGHLSARLTTLGPAATLARGYAVVQTMPDTNVLRTTADAPAGTHLRIRVADGAI
TAVSEGTDEAH

Sequences:

>Translated_411_residues
MTTPADDQGKSPENPWPVRAVATRVAKYIDRLGMVWIEGQLTELKIRQTTAWMVLRDPAADMSLSVSCPRDLVANAPVPL
SEGTQVIVLGKPQFYTRNGSFSLRISEIRAVGIGELLARIDRLRRLLDAEGLFDPRLKRPIPFLPGTIGLITGRASHAER
DVMTVAANRWPAVRFAVRNTIVQGPNAVPQIVGALRELDRDPGVDVIVLARGGGSVEDLLPFSDETLCREIASCTTPVVS
AVGHEPDNPLCDLVADLRAATPTDAAKRVVPDAAAEQAFVTDLRRRSARALRQWVHREQHHLDQLRSRPVLARPLQAIDA
RADEVHRAVAAARRDVRRMVTVESERVGHLSARLTTLGPAATLARGYAVVQTMPDTNVLRTTADAPAGTHLRIRVADGAI
TAVSEGTDEAH
>Mature_410_residues
TTPADDQGKSPENPWPVRAVATRVAKYIDRLGMVWIEGQLTELKIRQTTAWMVLRDPAADMSLSVSCPRDLVANAPVPLS
EGTQVIVLGKPQFYTRNGSFSLRISEIRAVGIGELLARIDRLRRLLDAEGLFDPRLKRPIPFLPGTIGLITGRASHAERD
VMTVAANRWPAVRFAVRNTIVQGPNAVPQIVGALRELDRDPGVDVIVLARGGGSVEDLLPFSDETLCREIASCTTPVVSA
VGHEPDNPLCDLVADLRAATPTDAAKRVVPDAAAEQAFVTDLRRRSARALRQWVHREQHHLDQLRSRPVLARPLQAIDAR
ADEVHRAVAAARRDVRRMVTVESERVGHLSARLTTLGPAATLARGYAVVQTMPDTNVLRTTADAPAGTHLRIRVADGAIT
AVSEGTDEAH

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=423, Percent_Identity=30.4964539007092, Blast_Score=163, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579 [H]

Pfam domain/function: PF02601 Exonuc_VII_L [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 44740; Mature: 44609

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPADDQGKSPENPWPVRAVATRVAKYIDRLGMVWIEGQLTELKIRQTTAWMVLRDPAA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCEEEEEEEEEEEEEEEECCCC
DMSLSVSCPRDLVANAPVPLSEGTQVIVLGKPQFYTRNGSFSLRISEIRAVGIGELLARI
CCEEECCCCHHHHCCCCCCCCCCCEEEEECCCCEEEECCCEEEEEHHHHHCCHHHHHHHH
DRLRRLLDAEGLFDPRLKRPIPFLPGTIGLITGRASHAERDVMTVAANRWPAVRFAVRNT
HHHHHHHHCCCCCCCHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHH
IVQGPNAVPQIVGALRELDRDPGVDVIVLARGGGSVEDLLPFSDETLCREIASCTTPVVS
HHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
AVGHEPDNPLCDLVADLRAATPTDAAKRVVPDAAAEQAFVTDLRRRSARALRQWVHREQH
HHCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLDQLRSRPVLARPLQAIDARADEVHRAVAAARRDVRRMVTVESERVGHLSARLTTLGPA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHH
ATLARGYAVVQTMPDTNVLRTTADAPAGTHLRIRVADGAITAVSEGTDEAH
HHHHHCEEEEEECCCCCCEEECCCCCCCCEEEEEEECCCEEEECCCCCCCC
>Mature Secondary Structure 
TTPADDQGKSPENPWPVRAVATRVAKYIDRLGMVWIEGQLTELKIRQTTAWMVLRDPAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCEEEEEEEEEEEEEEEECCCC
DMSLSVSCPRDLVANAPVPLSEGTQVIVLGKPQFYTRNGSFSLRISEIRAVGIGELLARI
CCEEECCCCHHHHCCCCCCCCCCCEEEEECCCCEEEECCCEEEEEHHHHHCCHHHHHHHH
DRLRRLLDAEGLFDPRLKRPIPFLPGTIGLITGRASHAERDVMTVAANRWPAVRFAVRNT
HHHHHHHHCCCCCCCHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHH
IVQGPNAVPQIVGALRELDRDPGVDVIVLARGGGSVEDLLPFSDETLCREIASCTTPVVS
HHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
AVGHEPDNPLCDLVADLRAATPTDAAKRVVPDAAAEQAFVTDLRRRSARALRQWVHREQH
HHCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLDQLRSRPVLARPLQAIDARADEVHRAVAAARRDVRRMVTVESERVGHLSARLTTLGPA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHH
ATLARGYAVVQTMPDTNVLRTTADAPAGTHLRIRVADGAITAVSEGTDEAH
HHHHHCEEEEEECCCCCCEEECCCCCCCCEEEEEEECCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA