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The map label for this gene is yajO [H]

Identifier: 119870181

GI number: 119870181

Start: 4379531

End: 4380559

Strand: Direct

Name: yajO [H]

Synonym: Mkms_4151

Alternate gene names: 119870181

Gene position: 4379531-4380559 (Clockwise)

Preceding gene: 119870177

Following gene: 119870183

Centisome position: 76.34

GC content: 69.97

Gene sequence:

>1029_bases
ATGGAGTATCGGCGGGTTGGCGAATCGGGTCTGACGGTGTCGGAGATCAGTTTCGGCGCAGCGACATTCGGCGGGGTCGG
CGACTTCTTCGGCGCCTGGGGCGATACCGGCGTCGAGGGCGCGCGTCGCATCGTGGACATCTGCCTGGAGGCTGGTGTCA
CGCTGTTCGACACCGCGGACGTGTACTCCGACGGCGCCTCGGAGGAGGTGCTCGGCGAAGCCCTGCGCGGCCGGCGCGAC
CGGGTGCTCATCTCCACCAAGGCCGCGCTGCCCACCTCGACCGGCTGGGGCACCTCACGCGCTCGGTTGCTGCGTGCGGT
CGAGGATGCGCTGCGGCGGTTGCGGACCGACCGCATCGACCTGTTCCAACTGCACGGCTACGACTCGGGGACGCCGATCG
AGGAAGTCGTGGCGACCCTCGACACGCTGCTCACGCAGGGCAAGGTGCGCTACACCGGCGTGTCGAACTTCTCCGGATGG
CAGTTGATGAAATCGCTGGCGGTCGCCGACGGCGCACACCGCACCCGCCACATCGCCCATCAGGTCTACTACTCGCTCGT
CGGGCGGGATTACGAATGGGAACTCATGCCGCTGGGCCTTGCCGAGGGCGTCGGCGCGCTGGTGTGGAGTCCGCTGGGCT
GGGGACGGCTCACCGGCCGGATCCGGCGCGGACGACCGCTGCCCGAGCGCAGCCGCCTGCACGCGACCGCTGACGCGGGT
CCGCCCGTCGACGAGGATCGGCTCTACGCCGTCGTCGACACCCTCGACGACATCGCCGCGGAGACCGGACGCACCGTGGC
GCAGATCGCGCTCAACTGGCTCCTGCGGCGGCCGACCGTCGCCTCGGTGATCATCGGAGCCCGCAACGAGGAACAGCTGC
GCGAGAACCTGGGCGCCGTCGGCTGGCGACTCGACGACGAGCAGATCGCCCGGCTGGACGCGGTCAGCGCCCGGGAGGCG
CCGTATCCCTACTTCCCGTACCGCAGGCAGGAAGGTTTCGCACTGCTCGATCCGCCGGTGGCGGGTTAG

Upstream 100 bases:

>100_bases
CGCACCGCCCGCTCCGTCACCCCACCACCCTAACGGGAATGAATTCCCATCAAGACCCGTTGCGGCTCTATCGAGACAAT
CGTTTCATTAAGGAGGATTC

Downstream 100 bases:

>100_bases
CGGTGCATGTCCACCAGGTGCTGGTAGAGCGTGGCGTTGGTGCGGTTGCCGTCGACCTCCGCCTCGCTGAGTTCGCGCCG
AACCTTGCCCGGCACGCCGG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MEYRRVGESGLTVSEISFGAATFGGVGDFFGAWGDTGVEGARRIVDICLEAGVTLFDTADVYSDGASEEVLGEALRGRRD
RVLISTKAALPTSTGWGTSRARLLRAVEDALRRLRTDRIDLFQLHGYDSGTPIEEVVATLDTLLTQGKVRYTGVSNFSGW
QLMKSLAVADGAHRTRHIAHQVYYSLVGRDYEWELMPLGLAEGVGALVWSPLGWGRLTGRIRRGRPLPERSRLHATADAG
PPVDEDRLYAVVDTLDDIAAETGRTVAQIALNWLLRRPTVASVIIGARNEEQLRENLGAVGWRLDDEQIARLDAVSAREA
PYPYFPYRRQEGFALLDPPVAG

Sequences:

>Translated_342_residues
MEYRRVGESGLTVSEISFGAATFGGVGDFFGAWGDTGVEGARRIVDICLEAGVTLFDTADVYSDGASEEVLGEALRGRRD
RVLISTKAALPTSTGWGTSRARLLRAVEDALRRLRTDRIDLFQLHGYDSGTPIEEVVATLDTLLTQGKVRYTGVSNFSGW
QLMKSLAVADGAHRTRHIAHQVYYSLVGRDYEWELMPLGLAEGVGALVWSPLGWGRLTGRIRRGRPLPERSRLHATADAG
PPVDEDRLYAVVDTLDDIAAETGRTVAQIALNWLLRRPTVASVIIGARNEEQLRENLGAVGWRLDDEQIARLDAVSAREA
PYPYFPYRRQEGFALLDPPVAG
>Mature_342_residues
MEYRRVGESGLTVSEISFGAATFGGVGDFFGAWGDTGVEGARRIVDICLEAGVTLFDTADVYSDGASEEVLGEALRGRRD
RVLISTKAALPTSTGWGTSRARLLRAVEDALRRLRTDRIDLFQLHGYDSGTPIEEVVATLDTLLTQGKVRYTGVSNFSGW
QLMKSLAVADGAHRTRHIAHQVYYSLVGRDYEWELMPLGLAEGVGALVWSPLGWGRLTGRIRRGRPLPERSRLHATADAG
PPVDEDRLYAVVDTLDDIAAETGRTVAQIALNWLLRRPTVASVIIGARNEEQLRENLGAVGWRLDDEQIARLDAVSAREA
PYPYFPYRRQEGFALLDPPVAG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=341, Percent_Identity=32.8445747800587, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI27436962, Length=341, Percent_Identity=32.8445747800587, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI27436966, Length=341, Percent_Identity=32.5513196480938, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI27436969, Length=341, Percent_Identity=32.8445747800587, Blast_Score=152, Evalue=6e-37,
Organism=Homo sapiens, GI4504825, Length=339, Percent_Identity=32.7433628318584, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI27436971, Length=311, Percent_Identity=31.5112540192926, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI223718702, Length=274, Percent_Identity=29.5620437956204, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41327764, Length=280, Percent_Identity=28.2142857142857, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI41152114, Length=177, Percent_Identity=33.8983050847458, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI223718708, Length=130, Percent_Identity=38.4615384615385, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI87081735, Length=336, Percent_Identity=37.797619047619, Blast_Score=201, Evalue=8e-53,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=31.6109422492401, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1789199, Length=351, Percent_Identity=30.1994301994302, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1788081, Length=265, Percent_Identity=30.188679245283, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788070, Length=335, Percent_Identity=29.2537313432836, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI48994888, Length=287, Percent_Identity=26.4808362369338, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=356, Percent_Identity=27.8089887640449, Blast_Score=134, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323998, Length=331, Percent_Identity=29.0030211480363, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6319958, Length=307, Percent_Identity=27.6872964169381, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319951, Length=333, Percent_Identity=25.5255255255255, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=263, Percent_Identity=26.615969581749, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6321052, Length=156, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24646155, Length=333, Percent_Identity=26.7267267267267, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640980, Length=325, Percent_Identity=25.8461538461538, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI45549126, Length=325, Percent_Identity=25.8461538461538, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646159, Length=313, Percent_Identity=26.8370607028754, Blast_Score=82, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37539; Mature: 37539

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRRVGESGLTVSEISFGAATFGGVGDFFGAWGDTGVEGARRIVDICLEAGVTLFDTAD
CCCHHCCCCCCCHHHCCCCCHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECHH
VYSDGASEEVLGEALRGRRDRVLISTKAALPTSTGWGTSRARLLRAVEDALRRLRTDRID
HHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCE
LFQLHGYDSGTPIEEVVATLDTLLTQGKVRYTGVSNFSGWQLMKSLAVADGAHRTRHIAH
EEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHH
QVYYSLVGRDYEWELMPLGLAEGVGALVWSPLGWGRLTGRIRRGRPLPERSRLHATADAG
HHHHHHHCCCCCEEEEECCHHHCCHHHHCCCCCCHHHHHHHHCCCCCCCHHCEEEECCCC
PPVDEDRLYAVVDTLDDIAAETGRTVAQIALNWLLRRPTVASVIIGARNEEQLRENLGAV
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHEECCCCHHHHHHHHCCC
GWRLDDEQIARLDAVSAREAPYPYFPYRRQEGFALLDPPVAG
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCC
>Mature Secondary Structure
MEYRRVGESGLTVSEISFGAATFGGVGDFFGAWGDTGVEGARRIVDICLEAGVTLFDTAD
CCCHHCCCCCCCHHHCCCCCHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECHH
VYSDGASEEVLGEALRGRRDRVLISTKAALPTSTGWGTSRARLLRAVEDALRRLRTDRID
HHCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCE
LFQLHGYDSGTPIEEVVATLDTLLTQGKVRYTGVSNFSGWQLMKSLAVADGAHRTRHIAH
EEEEECCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHH
QVYYSLVGRDYEWELMPLGLAEGVGALVWSPLGWGRLTGRIRRGRPLPERSRLHATADAG
HHHHHHHCCCCCEEEEECCHHHCCHHHHCCCCCCHHHHHHHHCCCCCCCHHCEEEECCCC
PPVDEDRLYAVVDTLDDIAAETGRTVAQIALNWLLRRPTVASVIIGARNEEQLRENLGAV
CCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHEECCCCHHHHHHHHCCC
GWRLDDEQIARLDAVSAREAPYPYFPYRRQEGFALLDPPVAG
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]