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The map label for this gene is ywcA [H]

Identifier: 119870158

GI number: 119870158

Start: 4358953

End: 4360689

Strand: Direct

Name: ywcA [H]

Synonym: Mkms_4128

Alternate gene names: 119870158

Gene position: 4358953-4360689 (Clockwise)

Preceding gene: 119870157

Following gene: 119870159

Centisome position: 75.98

GC content: 71.5

Gene sequence:

>1737_bases
ATGACCGGTTCGGCGTTGACGGCGGCCGCGCTGCTCGCCGCGGCGGTGGCCACCATCGCGATCGGCGCCTACGGTGTCCG
GTTCTCCCGCACCACCTCCGACTTCCTGGTCGCCTCCCGCACGGTCGGGCCGCAATGGAACGCGGCCGCCATCTCCGGCG
AATACCTCTCCGCTGCATCGTTTCTCGGCGTCGCCGGGCTGATCGCGAAATACGGCGCCGACGCGCTGTGGTATCCGGTC
GGTTTCACCGCGGGCTATCTGGGCCTGCTGCTGTTCGTGGCGGCGCCGCTGCGTCGTTCCGGGGCCTACACGGTGCCCGA
CTTCGCCGAGTTCCGGCTCGGGTCACGGCGGCTGCGCAAGGTCGCGATGCTCGTCGTCATCGTGATCTGCGTGGTGTATC
TCGTCCCGCAGTACCAGGGCGCCGGCCTCGCACTCAAGACCCTGCTGGGCATGCCGGTGTGGATCGGGCCGGTGGTCGTC
GGCGGCATCGTCATCACCAACGTGGTCGCCGGTGGCATGCGCTCGATCACCTTCGTGCAGGCCTTCCAGTACTGGCTGAA
ACTGACGGCGATCGCCATTCCCGCGATCGCGCTGCTCGGACTGTTCTTCACCGACCGGGGCGAACTGGGTGGGCCGCTCC
CGCCGTCCGTCACCCAGGACACGACCGTCGCCATCGAGACCGACGTCGTCGTGCAGGTCACCGAACCGGCCGGCATCACG
GTGACGGGCACGCTCGACGGCCGGCCGGTCATCGCCGCACCCATCGGCGCGCCCGGGGAACATGAGTTGGGCGCGGATTC
CACGATGACGCTGGCCGACGGCGCGGCCACGCCCGTGCTGGCGGGCACCCCGGCGGCCGGCGGTGAATGGCTCGCCTCCG
GCGGCGGCCTGGGTGGCGCGCATCCGCTCTACCAGGTCGTCTCGATCATCGTGGCGACGTTCCTCGGCACGATGGGGCTG
CCGCATGTACTGGTGCGCTTCTACACCAACCCCGACGGCAGGGTCGCCCGGCGCACCGCGCTCGCGGTCATCGCGCTGCT
GGGGTTGTTCTACCTGTTCCCCACGCTGATCGGCGTGTTCTCCCGGCTCTACGTACCGCAGCTTCTCATCACCGGCGCCG
CCGACGCAGCGGTCCTGCTCGCCCCCGCCGCCGCGATCGGCGGGGTGTTCGGGCAGCTGCTCGCCGCACTCGTCGCCGCC
GGGGCGATCGCGGCGTTTCTCGCGACGTCGTCGGGTCTGCTGGTGAGCATCGCCGGTGCGTTGGCGACCGACGTGCTGCG
TGGCCGGGTGCGGGACTTCCGGATCGCCGCGCTCGTCGGCGGGCTGATCCCGATCCCCTTGTCGCTCATCACCTCCGGAC
TGGAGTTGTCGCGCAGCGTCGGGCTGGCGTTCGCGGTGGCCGCATCCACGCTGTGCCCGCTGCTGGTGCTGGGCATCTGG
TGGCGGGGGCTGACCGCGGTCGGTGCGTCCTGCGGCCTGGTGGTCGGCGGGGCGGCCTCGGGGACGGCGGTGGCCCTCGC
GATCGCGGGTGCGGTCGACGAAGCGGCGCTCGGCGGGTGGGCCGCGGTGGCCGTCGGCTATCCCGCCGCGATCACCGTCC
CGCTGGCCTTCGTCACGATGATCGCCGTCAGCCGGCTCACCCGGCGCAGCGTCCCGCCCGATGTCGCCCAGATCTTCGCG
CGGATGCACGTGCCCGAACGGCTGGGCATGGGCATCGAACGCGTACCCGGCGACTGA

Upstream 100 bases:

>100_bases
GGCTGCTGGCGTACCCACTGATGTACGGGGTGGGCAGGCTCTACGTCCGATTGGCCGAACAGGCCGAGCGCGACTTCGTC
CGCGTCATCGACAGCGAGCC

Downstream 100 bases:

>100_bases
CCTCGCGCCTGCGCGGGCGCCGCCGTTCGTCGCCGGCATCCGACCGCTCACCGCACCGCTGTCGGCCTTCACCGTGTGAC
CTCCCCGAGGTGCGGGTATG

Product: Na+/solute symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MTGSALTAAALLAAAVATIAIGAYGVRFSRTTSDFLVASRTVGPQWNAAAISGEYLSAASFLGVAGLIAKYGADALWYPV
GFTAGYLGLLLFVAAPLRRSGAYTVPDFAEFRLGSRRLRKVAMLVVIVICVVYLVPQYQGAGLALKTLLGMPVWIGPVVV
GGIVITNVVAGGMRSITFVQAFQYWLKLTAIAIPAIALLGLFFTDRGELGGPLPPSVTQDTTVAIETDVVVQVTEPAGIT
VTGTLDGRPVIAAPIGAPGEHELGADSTMTLADGAATPVLAGTPAAGGEWLASGGGLGGAHPLYQVVSIIVATFLGTMGL
PHVLVRFYTNPDGRVARRTALAVIALLGLFYLFPTLIGVFSRLYVPQLLITGAADAAVLLAPAAAIGGVFGQLLAALVAA
GAIAAFLATSSGLLVSIAGALATDVLRGRVRDFRIAALVGGLIPIPLSLITSGLELSRSVGLAFAVAASTLCPLLVLGIW
WRGLTAVGASCGLVVGGAASGTAVALAIAGAVDEAALGGWAAVAVGYPAAITVPLAFVTMIAVSRLTRRSVPPDVAQIFA
RMHVPERLGMGIERVPGD

Sequences:

>Translated_578_residues
MTGSALTAAALLAAAVATIAIGAYGVRFSRTTSDFLVASRTVGPQWNAAAISGEYLSAASFLGVAGLIAKYGADALWYPV
GFTAGYLGLLLFVAAPLRRSGAYTVPDFAEFRLGSRRLRKVAMLVVIVICVVYLVPQYQGAGLALKTLLGMPVWIGPVVV
GGIVITNVVAGGMRSITFVQAFQYWLKLTAIAIPAIALLGLFFTDRGELGGPLPPSVTQDTTVAIETDVVVQVTEPAGIT
VTGTLDGRPVIAAPIGAPGEHELGADSTMTLADGAATPVLAGTPAAGGEWLASGGGLGGAHPLYQVVSIIVATFLGTMGL
PHVLVRFYTNPDGRVARRTALAVIALLGLFYLFPTLIGVFSRLYVPQLLITGAADAAVLLAPAAAIGGVFGQLLAALVAA
GAIAAFLATSSGLLVSIAGALATDVLRGRVRDFRIAALVGGLIPIPLSLITSGLELSRSVGLAFAVAASTLCPLLVLGIW
WRGLTAVGASCGLVVGGAASGTAVALAIAGAVDEAALGGWAAVAVGYPAAITVPLAFVTMIAVSRLTRRSVPPDVAQIFA
RMHVPERLGMGIERVPGD
>Mature_577_residues
TGSALTAAALLAAAVATIAIGAYGVRFSRTTSDFLVASRTVGPQWNAAAISGEYLSAASFLGVAGLIAKYGADALWYPVG
FTAGYLGLLLFVAAPLRRSGAYTVPDFAEFRLGSRRLRKVAMLVVIVICVVYLVPQYQGAGLALKTLLGMPVWIGPVVVG
GIVITNVVAGGMRSITFVQAFQYWLKLTAIAIPAIALLGLFFTDRGELGGPLPPSVTQDTTVAIETDVVVQVTEPAGITV
TGTLDGRPVIAAPIGAPGEHELGADSTMTLADGAATPVLAGTPAAGGEWLASGGGLGGAHPLYQVVSIIVATFLGTMGLP
HVLVRFYTNPDGRVARRTALAVIALLGLFYLFPTLIGVFSRLYVPQLLITGAADAAVLLAPAAAIGGVFGQLLAALVAAG
AIAAFLATSSGLLVSIAGALATDVLRGRVRDFRIAALVGGLIPIPLSLITSGLELSRSVGLAFAVAASTLCPLLVLGIWW
RGLTAVGASCGLVVGGAASGTAVALAIAGAVDEAALGGWAAVAVGYPAAITVPLAFVTMIAVSRLTRRSVPPDVAQIFAR
MHVPERLGMGIERVPGD

Specific function: Unknown

COG id: COG4147

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Escherichia coli, GI1790503, Length=165, Percent_Identity=35.7575757575758, Blast_Score=96, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 58665; Mature: 58534

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSALTAAALLAAAVATIAIGAYGVRFSRTTSDFLVASRTVGPQWNAAAISGEYLSAAS
CCCHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHEECCCCCCCCCEEECCHHHHHHH
FLGVAGLIAKYGADALWYPVGFTAGYLGLLLFVAAPLRRSGAYTVPDFAEFRLGSRRLRK
HHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
VAMLVVIVICVVYLVPQYQGAGLALKTLLGMPVWIGPVVVGGIVITNVVAGGMRSITFVQ
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AFQYWLKLTAIAIPAIALLGLFFTDRGELGGPLPPSVTQDTTVAIETDVVVQVTEPAGIT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCEE
VTGTLDGRPVIAAPIGAPGEHELGADSTMTLADGAATPVLAGTPAAGGEWLASGGGLGGA
EEEECCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCCCCCCCCCC
HPLYQVVSIIVATFLGTMGLPHVLVRFYTNPDGRVARRTALAVIALLGLFYLFPTLIGVF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLYVPQLLITGAADAAVLLAPAAAIGGVFGQLLAALVAAGAIAAFLATSSGLLVSIAGA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LATDVLRGRVRDFRIAALVGGLIPIPLSLITSGLELSRSVGLAFAVAASTLCPLLVLGIW
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRGLTAVGASCGLVVGGAASGTAVALAIAGAVDEAALGGWAAVAVGYPAAITVPLAFVTM
HHHHHHHCCCCCEEECCCCCCCEEHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
IAVSRLTRRSVPPDVAQIFARMHVPERLGMGIERVPGD
HHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure 
TGSALTAAALLAAAVATIAIGAYGVRFSRTTSDFLVASRTVGPQWNAAAISGEYLSAAS
CCHHHHHHHHHHHHHHHHHHHHHCEEEECCCHHHHHEECCCCCCCCCEEECCHHHHHHH
FLGVAGLIAKYGADALWYPVGFTAGYLGLLLFVAAPLRRSGAYTVPDFAEFRLGSRRLRK
HHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
VAMLVVIVICVVYLVPQYQGAGLALKTLLGMPVWIGPVVVGGIVITNVVAGGMRSITFVQ
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHH
AFQYWLKLTAIAIPAIALLGLFFTDRGELGGPLPPSVTQDTTVAIETDVVVQVTEPAGIT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEEEEEECCCCEE
VTGTLDGRPVIAAPIGAPGEHELGADSTMTLADGAATPVLAGTPAAGGEWLASGGGLGGA
EEEECCCCEEEEECCCCCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCCCCCCCCCC
HPLYQVVSIIVATFLGTMGLPHVLVRFYTNPDGRVARRTALAVIALLGLFYLFPTLIGVF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRLYVPQLLITGAADAAVLLAPAAAIGGVFGQLLAALVAAGAIAAFLATSSGLLVSIAGA
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LATDVLRGRVRDFRIAALVGGLIPIPLSLITSGLELSRSVGLAFAVAASTLCPLLVLGIW
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WRGLTAVGASCGLVVGGAASGTAVALAIAGAVDEAALGGWAAVAVGYPAAITVPLAFVTM
HHHHHHHCCCCCEEECCCCCCCEEHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHH
IAVSRLTRRSVPPDVAQIFARMHVPERLGMGIERVPGD
HHHHHHHHCCCCHHHHHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]