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The map label for this gene is dppB [C]

Identifier: 119870032

GI number: 119870032

Start: 4218583

End: 4219560

Strand: Direct

Name: dppB [C]

Synonym: Mkms_4002

Alternate gene names: 119870032

Gene position: 4218583-4219560 (Clockwise)

Preceding gene: 119870031

Following gene: 119870033

Centisome position: 73.53

GC content: 67.89

Gene sequence:

>978_bases
ATGACGCGGTTCCTCGCGCGCCGGCTGCTCAACTACGTCGTGCTGTTGGCGCTCGCATCGTTTTTGACGTTCACGCTGAC
CTCCCTGACCTTCGAACCGCTCGACAGCCTGCTGCAGCGCAACCCGCGGCCCCCGCAGTCGACCATCGACGCGAAGGCGG
CCGAACTCAACCTCGACAAGCCCATCCCCGTGCGCTACGCGCAGTGGCTGGGTGACGCGGTGCGCGGCGACTTCGGCACC
ACGATCACCGGGCAGCCGGTCTCCGACGAGCTGGGCCGCCGGATCGGGGTCAGCCTGCGGTTGCTGGTGATCGGGTCGGT
GCTGGGCACGGTCATCGGGGTCGTGGTCGGCGCGTGGGGCGCGATCCGCCAGTACCGGCTGTCCGACCGGGTGATCACGC
TGTTGTCGCTGCTCGTGCTGTCCGCCCCGACGTTCGTCATCGCCAACCTGCTGATCCTCGGGGCGCTCAACGCCAACTCC
TGGCTCGGCGTGCAACTGTTCGAGTACACCGGCGAGACCTCACCCGACGCCGTCGGCGGCCCGTTCGACCAGTTCGTCGA
CCGGTTGCAGCACCTGATCCTGCCGACGGTCACGCTCGCGTTGGCGGCCATCGCCGGGTTCAGCCGCTATCAGCGCAACG
CGATGCTCGACGTCCTCGGCCAGGACTTCATCCGCACCGCGCGCGCCAAGGGTCTGACCCGGCGCCAGGCACTGTTCAAA
CACGGTCTGCGCACCGCGCTCATCCCGATGGCGACGCTGTTCGCCTACGGGGTGAGCGGACTCGTGACCGGCGCGGTGTT
CGTCGAGAAGATCTTCGGCTGGCACGGGATGGGCGAATGGGTGGTGCAGGGCATCGCCACGCAGGACACCAACATCATCG
CGGCGATCACGGTGTTCTCCGGCGCCATGATCCTGTTGGCCGGGTTGCTGTCCGACGTGATCTACGCGGCGCTGGACCCG
AGAGTGCGGGTGCAGTGA

Upstream 100 bases:

>100_bases
CGGCGGGCCGGGCGCCCCGCCGCCGCCGCAGCCCTGAGCCTGCGAACGGGGAGTTTTCTTCTACCCTCTAGCCCATGCAG
CCCTGCACCGGCAGTCGCCG

Downstream 100 bases:

>100_bases
TGATGAGCGATTCGACGAGTACGACGGCGCGCTCGGGGCTGGACACCTCGCGGTTCGCCTCGCGCCGGACGCTGGTGACG
CGACGGTTCCTGCGCAACAA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MTRFLARRLLNYVVLLALASFLTFTLTSLTFEPLDSLLQRNPRPPQSTIDAKAAELNLDKPIPVRYAQWLGDAVRGDFGT
TITGQPVSDELGRRIGVSLRLLVIGSVLGTVIGVVVGAWGAIRQYRLSDRVITLLSLLVLSAPTFVIANLLILGALNANS
WLGVQLFEYTGETSPDAVGGPFDQFVDRLQHLILPTVTLALAAIAGFSRYQRNAMLDVLGQDFIRTARAKGLTRRQALFK
HGLRTALIPMATLFAYGVSGLVTGAVFVEKIFGWHGMGEWVVQGIATQDTNIIAAITVFSGAMILLAGLLSDVIYAALDP
RVRVQ

Sequences:

>Translated_325_residues
MTRFLARRLLNYVVLLALASFLTFTLTSLTFEPLDSLLQRNPRPPQSTIDAKAAELNLDKPIPVRYAQWLGDAVRGDFGT
TITGQPVSDELGRRIGVSLRLLVIGSVLGTVIGVVVGAWGAIRQYRLSDRVITLLSLLVLSAPTFVIANLLILGALNANS
WLGVQLFEYTGETSPDAVGGPFDQFVDRLQHLILPTVTLALAAIAGFSRYQRNAMLDVLGQDFIRTARAKGLTRRQALFK
HGLRTALIPMATLFAYGVSGLVTGAVFVEKIFGWHGMGEWVVQGIATQDTNIIAAITVFSGAMILLAGLLSDVIYAALDP
RVRVQ
>Mature_324_residues
TRFLARRLLNYVVLLALASFLTFTLTSLTFEPLDSLLQRNPRPPQSTIDAKAAELNLDKPIPVRYAQWLGDAVRGDFGTT
ITGQPVSDELGRRIGVSLRLLVIGSVLGTVIGVVVGAWGAIRQYRLSDRVITLLSLLVLSAPTFVIANLLILGALNANSW
LGVQLFEYTGETSPDAVGGPFDQFVDRLQHLILPTVTLALAAIAGFSRYQRNAMLDVLGQDFIRTARAKGLTRRQALFKH
GLRTALIPMATLFAYGVSGLVTGAVFVEKIFGWHGMGEWVVQGIATQDTNIIAAITVFSGAMILLAGLLSDVIYAALDPR
VRVQ

Specific function: Part Of The Binding-Protein-Dependent Transport System For Dipeptides; Probably Responsible For The Translocation Of The Substrate Across The Membrane. [C]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=345, Percent_Identity=30.7246376811594, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1787053, Length=328, Percent_Identity=32.3170731707317, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1789888, Length=326, Percent_Identity=31.9018404907975, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1787497, Length=325, Percent_Identity=29.8461538461538, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787761, Length=331, Percent_Identity=32.02416918429, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787550, Length=268, Percent_Identity=27.6119402985075, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788504, Length=271, Percent_Identity=25.4612546125461, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 35246; Mature: 35115

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRFLARRLLNYVVLLALASFLTFTLTSLTFEPLDSLLQRNPRPPQSTIDAKAAELNLDK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCCC
PIPVRYAQWLGDAVRGDFGTTITGQPVSDELGRRIGVSLRLLVIGSVLGTVIGVVVGAWG
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIRQYRLSDRVITLLSLLVLSAPTFVIANLLILGALNANSWLGVQLFEYTGETSPDAVGG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHEECCCCCCCCCCCC
PFDQFVDRLQHLILPTVTLALAAIAGFSRYQRNAMLDVLGQDFIRTARAKGLTRRQALFK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
HGLRTALIPMATLFAYGVSGLVTGAVFVEKIFGWHGMGEWVVQGIATQDTNIIAAITVFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHH
GAMILLAGLLSDVIYAALDPRVRVQ
HHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TRFLARRLLNYVVLLALASFLTFTLTSLTFEPLDSLLQRNPRPPQSTIDAKAAELNLDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCHHHHCCCCC
PIPVRYAQWLGDAVRGDFGTTITGQPVSDELGRRIGVSLRLLVIGSVLGTVIGVVVGAWG
CCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIRQYRLSDRVITLLSLLVLSAPTFVIANLLILGALNANSWLGVQLFEYTGETSPDAVGG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHEECCCCCCCCCCCC
PFDQFVDRLQHLILPTVTLALAAIAGFSRYQRNAMLDVLGQDFIRTARAKGLTRRQALFK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
HGLRTALIPMATLFAYGVSGLVTGAVFVEKIFGWHGMGEWVVQGIATQDTNIIAAITVFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHH
GAMILLAGLLSDVIYAALDPRVRVQ
HHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]