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The map label for this gene is degU [H]

Identifier: 119870013

GI number: 119870013

Start: 4198462

End: 4199106

Strand: Direct

Name: degU [H]

Synonym: Mkms_3983

Alternate gene names: 119870013

Gene position: 4198462-4199106 (Clockwise)

Preceding gene: 119870012

Following gene: 119870014

Centisome position: 73.18

GC content: 67.29

Gene sequence:

>645_bases
ATGCGCATCGTGATCGCTGAGGACTCCGCGCTGCTGCGCGCCGGAATCGAGCGCATCCTCGCCGACGCCGGCCACGAGGT
GGTCGCCGGAGTTCCCGACGCCACCAACCTGTTACGACTGGTCAACGAGACCCGGCCCGATCTGGCGATCCTCGACGTCC
GGATGCCGCCGACCTTCACCGACGAGGGCATCCGCGCCGCCGCGCTGCTGCGCAGCCAGAACCCGGAGTCCCCGGTCCTG
GTTCTGTCGCACTACGTCGAGCAGCGCTACGCCGCCGAGTTGATCGCCTCGGACACAAAGGGTTTCGGCTACCTCCTGAA
GGACCGGGTGGCCGACGTCCCGGCCTTCCTCGACGCGGTCGAGGTCGTCGGCCACGGCGGTACGGTGCTGGATCCGGAGG
TGGTCTCCCAGATCCTGGTGCGGTCACACCGGCGCGCGGCACTCGACCAGTTGACTCCCCGTGAGCACGAGGTGCTCCAA
CTCATGGCGGAGGGCAAGACGAACTCGGCGATCGCGAGCGGGATGCACATCTCGGTCGGATCGGCCGAGAAGCACATCGC
CTCGATCTTCACAAAATTGAACCTCGCCCCCGACGAGACCGAGAACCGCCGCGTGCTGGCCGTCCTGCGGTTCCTCGAAT
CCTGA

Upstream 100 bases:

>100_bases
CCGGCCTGCGGGGGCTCGACGAACGGGTGCGCGCAGCGCGCGGCACGTTCACCGTGTCCAGCCCGACGACCGGGCCCACC
ATCGTCACCGCGGTGCTGCC

Downstream 100 bases:

>100_bases
ACGTGCGGAAGGACTTCCGATGACAACCATCGCTCCCCCACCCCCACCCCCCGCCCCGGTCGGTCCGCCGCCCGAGCTGT
CCCCCGGCGGACGGACCGCA

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MRIVIAEDSALLRAGIERILADAGHEVVAGVPDATNLLRLVNETRPDLAILDVRMPPTFTDEGIRAAALLRSQNPESPVL
VLSHYVEQRYAAELIASDTKGFGYLLKDRVADVPAFLDAVEVVGHGGTVLDPEVVSQILVRSHRRAALDQLTPREHEVLQ
LMAEGKTNSAIASGMHISVGSAEKHIASIFTKLNLAPDETENRRVLAVLRFLES

Sequences:

>Translated_214_residues
MRIVIAEDSALLRAGIERILADAGHEVVAGVPDATNLLRLVNETRPDLAILDVRMPPTFTDEGIRAAALLRSQNPESPVL
VLSHYVEQRYAAELIASDTKGFGYLLKDRVADVPAFLDAVEVVGHGGTVLDPEVVSQILVRSHRRAALDQLTPREHEVLQ
LMAEGKTNSAIASGMHISVGSAEKHIASIFTKLNLAPDETENRRVLAVLRFLES
>Mature_214_residues
MRIVIAEDSALLRAGIERILADAGHEVVAGVPDATNLLRLVNETRPDLAILDVRMPPTFTDEGIRAAALLRSQNPESPVL
VLSHYVEQRYAAELIASDTKGFGYLLKDRVADVPAFLDAVEVVGHGGTVLDPEVVSQILVRSHRRAALDQLTPREHEVLQ
LMAEGKTNSAIASGMHISVGSAEKHIASIFTKLNLAPDETENRRVLAVLRFLES

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=217, Percent_Identity=29.9539170506912, Blast_Score=67, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23282; Mature: 23282

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVIAEDSALLRAGIERILADAGHEVVAGVPDATNLLRLVNETRPDLAILDVRMPPTFT
CEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCC
DEGIRAAALLRSQNPESPVLVLSHYVEQRYAAELIASDTKGFGYLLKDRVADVPAFLDAV
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EVVGHGGTVLDPEVVSQILVRSHRRAALDQLTPREHEVLQLMAEGKTNSAIASGMHISVG
HHHCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCEEECC
SAEKHIASIFTKLNLAPDETENRRVLAVLRFLES
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure
MRIVIAEDSALLRAGIERILADAGHEVVAGVPDATNLLRLVNETRPDLAILDVRMPPTFT
CEEEEECCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHCCCCCEEEEEEECCCCCC
DEGIRAAALLRSQNPESPVLVLSHYVEQRYAAELIASDTKGFGYLLKDRVADVPAFLDAV
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EVVGHGGTVLDPEVVSQILVRSHRRAALDQLTPREHEVLQLMAEGKTNSAIASGMHISVG
HHHCCCCCEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHCCCEEECC
SAEKHIASIFTKLNLAPDETENRRVLAVLRFLES
CHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]