BacMap

Definition	Mycobacterium sp. KMS chromosome, complete genome.
Accession	NC_008705
Length	5,737,227

Click here to switch to the map view.

The map label for this gene is nodG [H]

Identifier: 119869781

GI number: 119869781

Start: 3970149

End: 3970850

Strand: Direct

Name: nodG [H]

Synonym: Mkms_3750

Alternate gene names: 119869781

Gene position: 3970149-3970850 (Clockwise)

Preceding gene: 119869770

Following gene: 119869782

Centisome position: 69.2

GC content: 68.52

Gene sequence:

>702_bases
GTGAAGACCGCCGTGGTCACCGGCGGAGGGTCGGGTATCGGACTGGCCATCGTGCAGCGGCTGCAGGCCGACGGGCTCCA
CGTCGCCACGATCGATCTCAAACCGGGCGACGGCGAGTTCGCCCACGCCGCCGACGTGACCGACCGGTCCGCGGTCGAGG
CCGCCTTCACCGCGATCCGCAAACAGCTCGGTCCGATCACCGTGCTCGTCAACGCCGCCGGGCTGGACTGCTTCAAACGC
TTCAGCGACGTGAACTTCGACCGCTGGCAGAAGGTCATCGACGTCAACCTCAACGGCGTCTTCCACACCATCCAGGCCGT
GCTGCCCGACATGCTCGAGGCGGGGTGGGGCCGCATCGTCAACATCTCGTCGTCGAGCACCCACTCGGGCGCCCCGTACA
TGTCGCCGTACGTGGCCGCCAAGTCGGCGGTCAACGGCCTGACGAAATCGCTTGCGCTGGAATACGGGCCGAGCGGTATC
ACGGTCAACGCCGTACCGCCCGGCTTCATCGACACCCCGATGCTGCGCGCCGCCGCCGAGCGCGGCTACCTCGGCGACAT
CGACGCCACGATCGCCGCCACCCCGGTGCGGCGCATGGGCAGACCAGAGGACATCGCCGCCGCCTGCGCGTTCCTCATCA
GCGAGGAGGCCGGCTACATCACCGGCCAGATCCTCGGCGTCAACGGCGGCCGTAACACCTGA

Upstream 100 bases:

>100_bases
AATGATCGACATCGAGAGTACGGTTCTCATAATCGGAAGGATGATTCTTGATGCTTGAGACGACCGAGACAGCCCCGGCC
GCCGGACAGGACAGAGCACT

Downstream 100 bases:

>100_bases
CGGTCATGCATCACCAACGGAATCAACCGGTTACACGAGAGGACAAGCTGTGGGGCGCGTAGAAGGCAAGGTCGCATTCA
TCACGGGCGCAGCGCGCGGG

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKTAVVTGGGSGIGLAIVQRLQADGLHVATIDLKPGDGEFAHAADVTDRSAVEAAFTAIRKQLGPITVLVNAAGLDCFKR
FSDVNFDRWQKVIDVNLNGVFHTIQAVLPDMLEAGWGRIVNISSSSTHSGAPYMSPYVAAKSAVNGLTKSLALEYGPSGI
TVNAVPPGFIDTPMLRAAAERGYLGDIDATIAATPVRRMGRPEDIAAACAFLISEEAGYITGQILGVNGGRNT

Sequences:

>Translated_233_residues
MKTAVVTGGGSGIGLAIVQRLQADGLHVATIDLKPGDGEFAHAADVTDRSAVEAAFTAIRKQLGPITVLVNAAGLDCFKR
FSDVNFDRWQKVIDVNLNGVFHTIQAVLPDMLEAGWGRIVNISSSSTHSGAPYMSPYVAAKSAVNGLTKSLALEYGPSGI
TVNAVPPGFIDTPMLRAAAERGYLGDIDATIAATPVRRMGRPEDIAAACAFLISEEAGYITGQILGVNGGRNT
>Mature_233_residues
MKTAVVTGGGSGIGLAIVQRLQADGLHVATIDLKPGDGEFAHAADVTDRSAVEAAFTAIRKQLGPITVLVNAAGLDCFKR
FSDVNFDRWQKVIDVNLNGVFHTIQAVLPDMLEAGWGRIVNISSSSTHSGAPYMSPYVAAKSAVNGLTKSLALEYGPSGI
TVNAVPPGFIDTPMLRAAAERGYLGDIDATIAATPVRRMGRPEDIAAACAFLISEEAGYITGQILGVNGGRNT

Specific function: Proposed to modify Nod factor fatty acyl chain [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=34.9593495934959, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI15277342, Length=249, Percent_Identity=36.5461847389558, Blast_Score=124, Evalue=5e-29,
Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=32.6693227091633, Blast_Score=107, Evalue=9e-24,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=29.2, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI10190704, Length=244, Percent_Identity=30.327868852459, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI40254992, Length=241, Percent_Identity=31.5352697095436, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=31.3807531380753, Blast_Score=98, Evalue=5e-21,
Organism=Homo sapiens, GI4758504, Length=249, Percent_Identity=29.718875502008, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI59889578, Length=192, Percent_Identity=34.8958333333333, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI66933014, Length=189, Percent_Identity=31.2169312169312, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=29.3877551020408, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=30.6532663316583, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI210032110, Length=193, Percent_Identity=26.4248704663212, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI83715985, Length=249, Percent_Identity=28.1124497991968, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=28.8770053475936, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI40807363, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI4503301, Length=227, Percent_Identity=24.6696035242291, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=30.8510638297872, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=29.3193717277487, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI223718074, Length=191, Percent_Identity=31.413612565445, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI210032112, Length=126, Percent_Identity=30.952380952381, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI31542939, Length=204, Percent_Identity=28.4313725490196, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI7705855, Length=189, Percent_Identity=31.7460317460317, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI25282469, Length=145, Percent_Identity=31.7241379310345, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI20149619, Length=130, Percent_Identity=32.3076923076923, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7706318, Length=205, Percent_Identity=28.2926829268293, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI302344755, Length=124, Percent_Identity=35.4838709677419, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=38.2716049382716, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI87082100, Length=246, Percent_Identity=36.5853658536585, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=31.9838056680162, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=34.9206349206349, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788459, Length=177, Percent_Identity=41.8079096045198, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=33.1932773109244, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=32.5102880658436, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI87082160, Length=244, Percent_Identity=29.0983606557377, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786812, Length=238, Percent_Identity=30.672268907563, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=29.6747967479675, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1789057, Length=254, Percent_Identity=30.3149606299213, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789378, Length=248, Percent_Identity=27.4193548387097, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1787820, Length=221, Percent_Identity=26.6968325791855, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=29.5081967213115, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=39.4190871369295, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=36.6255144032922, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=29.4820717131474, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=30.241935483871, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17538182, Length=246, Percent_Identity=30.4878048780488, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=30.5555555555556, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=29.718875502008, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17561272, Length=197, Percent_Identity=32.994923857868, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17538480, Length=259, Percent_Identity=31.2741312741313, Blast_Score=89, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=27.8884462151394, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=28.6290322580645, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=28.2352941176471, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=257, Percent_Identity=30.3501945525292, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=256, Percent_Identity=29.6875, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=29.5719844357977, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565030, Length=258, Percent_Identity=30.2325581395349, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=259, Percent_Identity=28.1853281853282, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=28.9473684210526, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=27.906976744186, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17564282, Length=259, Percent_Identity=25.0965250965251, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=254, Percent_Identity=27.9527559055118, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=28.030303030303, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=255, Percent_Identity=29.0196078431373, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=193, Percent_Identity=27.4611398963731, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=256, Percent_Identity=26.5625, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=195, Percent_Identity=26.1538461538462, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=26.171875, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=27.4900398406374, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=257, Percent_Identity=26.4591439688716, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=259, Percent_Identity=23.9382239382239, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=187, Percent_Identity=32.0855614973262, Blast_Score=99, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320089, Length=188, Percent_Identity=28.7234042553192, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=203, Percent_Identity=28.0788177339901, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397609, Length=245, Percent_Identity=33.0612244897959, Blast_Score=107, Evalue=6e-24,
Organism=Drosophila melanogaster, GI21355319, Length=253, Percent_Identity=29.6442687747036, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=31.0483870967742, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24639444, Length=243, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24643142, Length=239, Percent_Identity=30.5439330543933, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24644337, Length=224, Percent_Identity=32.1428571428571, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=29.9595141700405, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24644339, Length=253, Percent_Identity=28.0632411067194, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI221331218, Length=198, Percent_Identity=34.3434343434343, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=34.3434343434343, Blast_Score=78, Evalue=4e-15,
Organism=Drosophila melanogaster, GI17737361, Length=255, Percent_Identity=29.4117647058824, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24649181, Length=188, Percent_Identity=31.3829787234043, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221331216, Length=199, Percent_Identity=34.1708542713568, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24665247, Length=199, Percent_Identity=34.1708542713568, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=29.4736842105263, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281364892, Length=172, Percent_Identity=31.9767441860465, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24665264, Length=194, Percent_Identity=31.4432989690722, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24640442, Length=194, Percent_Identity=30.4123711340206, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581726, Length=158, Percent_Identity=28.4810126582279, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859837, Length=186, Percent_Identity=31.7204301075269, Blast_Score=67, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641232, Length=237, Percent_Identity=29.957805907173, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011283
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 24311; Mature: 24311

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAVVTGGGSGIGLAIVQRLQADGLHVATIDLKPGDGEFAHAADVTDRSAVEAAFTAIR
CCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
KQLGPITVLVNAAGLDCFKRFSDVNFDRWQKVIDVNLNGVFHTIQAVLPDMLEAGWGRIV
HHCCCEEEEEECCCHHHHHHHHCCCHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCCEEE
NISSSSTHSGAPYMSPYVAAKSAVNGLTKSLALEYGPSGITVNAVPPGFIDTPMLRAAAE
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCHHHHHHHH
RGYLGDIDATIAATPVRRMGRPEDIAAACAFLISEEAGYITGQILGVNGGRNT
CCCCCCCCCHHHHCCHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC
>Mature Secondary Structure
MKTAVVTGGGSGIGLAIVQRLQADGLHVATIDLKPGDGEFAHAADVTDRSAVEAAFTAIR
CCEEEEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHH
KQLGPITVLVNAAGLDCFKRFSDVNFDRWQKVIDVNLNGVFHTIQAVLPDMLEAGWGRIV
HHCCCEEEEEECCCHHHHHHHHCCCHHHHHHEEEECCCHHHHHHHHHHHHHHHCCCCEEE
NISSSSTHSGAPYMSPYVAAKSAVNGLTKSLALEYGPSGITVNAVPPGFIDTPMLRAAAE
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCEEEECCCCCCCCCHHHHHHHH
RGYLGDIDATIAATPVRRMGRPEDIAAACAFLISEEAGYITGQILGVNGGRNT
CCCCCCCCCHHHHCCHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1538694; 2243795 [H]