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The map label for this gene is yfnA [H]

Identifier: 119869637

GI number: 119869637

Start: 3790660

End: 3792279

Strand: Direct

Name: yfnA [H]

Synonym: Mkms_3605

Alternate gene names: 119869637

Gene position: 3790660-3792279 (Clockwise)

Preceding gene: 119869627

Following gene: 119869638

Centisome position: 66.07

GC content: 65.37

Gene sequence:

>1620_bases
ATGGCCAAGGAGAACCGAAGCCCGCGTCGGGTAAACGCTTTGTTACCTGGCTTGACGATGATGTGGCTCACACCCATACT
ACGGTTCAACCACATGGTCTATACCAACTCTGGAGGAACGATGTCCGGTCCTGTTCCCGGCGACGGTGACGCCGCCGAAC
TCGCACAGTTCGGCTACTCCCAATCCCTCGAGCGGCGCACCGGGAAGTTCGCGTCGTTCGCCGTGGCGTTCGCGTTCGTC
TCGATCGCCACCGGCATCTTCACCACCTACGGATCGGTGCTGAACTCCTCGGGTCCGATCGGTATCTGGACGTGGCCGAT
CGCGGTCGTCGGCCAGTTGGCGGTGGCCTTCGTCCTGGGCGCGCTGGCCTCCCGGATCCCCGTGACCGGCTACCACTACC
AGTGGATGTCACGCCTGGCCAACCCCGTGCTGGGCTGGATCATCGGCTGGATCTCGTTCACGTTCCTGGCCATCGTGGTC
TGCGCGGTCGACTACACGATCGCCTCGACGATCCTGCCGGTGCTGCTGAACTACGAGAGCACCGCCACCATCGCCTGGCT
GATCACCGCCGGCGTGCTGCTGATCCAGTTCCTGCTCGTGGCGTTCTCGACGCCCTGGGCCGAACGCGTCAACAACAGCT
TCGTCACCCTCGAACTGATCGGCATGGTGGCGCTCACGGTGCTGCTGCTCGTGGTCGCCGCGATCCGCGGGGACATGGAC
TTCGGCAACCTGTTCAGCAAGGGCGCAGTTCCAGCCGAGGGGTTCTGGAGCTTCGGCGACTGGACGTCGGCGGGCCCCTG
GATGCTGGGCTTCCTGCTCGGCGCCTTCACCATCGTCGGCTTCGAATCGGCCGCCAACCTCGCCGAGGAGACCCACGACC
CCGAACGCGTGGTGCCGCGCGCGATGTGCCAGGCCGTGCTCGCCTCCGGTGTGCTGGGCTTCTTGTTCCTGGTCGCGGTG
ACGCTGGCCGCGGGCGATCCCATCGCACTCGCCGAATCCGGGACGCCGATCGCCGACGTCATCGAATCGACCCTCGGCTC
GGTCGTGGCGACACTGCTGCTGCTGATGGTGGTGCTGGCGATCTTCGCGTGCGGTCTGGTCATCATGATCACCGGCGTGC
GGCTCACCTGGGCGATGTCGCGGGACAAGCGCTTCCCCGGCTGGCAGCAGTGGGACCAGATCTCGTCGCGGTTCCACACC
CCATTCAAGGCCGCGGTGCTCTACTTCGTCGTCGCCAACCTCATCCTGGCGATCTTCTCCCGCTCGGAGACCGCGCTGTT
CACGCTGTTCGGCGCCGCCACCCTGCTGCCCGCGGTGATGTACGCCTCGACCGTGGTGCTCTACCTGATCAAGCGCAAGT
CGTTGCCCGCCAACGGGAAATTCGACCTCGGCGCGTGGGAGATCCCGGTCGTCGCGGTGGCAGTGGTCTGGCTGGCCTTC
GAACTGGCGCTGTTCCGCGATTCGAGTTTCAAAGAGGCGTGGTCCTACGTCATCGTCATGGTGGTGATCGGTGCGCTGTA
CCTGGGGTACCTGCTGGCCACCCGCGGCCGCCACGGCTTGTCGATGCCCGATATGCACTCGATCGACGCCGAACTCGACC
GTGAGGCCGCGAAGGACTGA

Upstream 100 bases:

>100_bases
CCGCGATGGCGAGGTAACGCGGTGGGTCGCCACCGCCCTGCGGCGGGCTCTTCCTGGCGGCGGCCGGCATGTCTGCAGCG
TAGCCGGGTGCTGGATTCAC

Downstream 100 bases:

>100_bases
TGACACATCTGCTCGCCATCGATCAGGGCACGTCGGGGACGAAGGCGATCGTCGTCGACTACGGCTCCGACGGGTCCGGT
CGGGTGGTCTCGGTCGCCGA

Product: amino acid permease-associated protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MAKENRSPRRVNALLPGLTMMWLTPILRFNHMVYTNSGGTMSGPVPGDGDAAELAQFGYSQSLERRTGKFASFAVAFAFV
SIATGIFTTYGSVLNSSGPIGIWTWPIAVVGQLAVAFVLGALASRIPVTGYHYQWMSRLANPVLGWIIGWISFTFLAIVV
CAVDYTIASTILPVLLNYESTATIAWLITAGVLLIQFLLVAFSTPWAERVNNSFVTLELIGMVALTVLLLVVAAIRGDMD
FGNLFSKGAVPAEGFWSFGDWTSAGPWMLGFLLGAFTIVGFESAANLAEETHDPERVVPRAMCQAVLASGVLGFLFLVAV
TLAAGDPIALAESGTPIADVIESTLGSVVATLLLLMVVLAIFACGLVIMITGVRLTWAMSRDKRFPGWQQWDQISSRFHT
PFKAAVLYFVVANLILAIFSRSETALFTLFGAATLLPAVMYASTVVLYLIKRKSLPANGKFDLGAWEIPVVAVAVVWLAF
ELALFRDSSFKEAWSYVIVMVVIGALYLGYLLATRGRHGLSMPDMHSIDAELDREAAKD

Sequences:

>Translated_539_residues
MAKENRSPRRVNALLPGLTMMWLTPILRFNHMVYTNSGGTMSGPVPGDGDAAELAQFGYSQSLERRTGKFASFAVAFAFV
SIATGIFTTYGSVLNSSGPIGIWTWPIAVVGQLAVAFVLGALASRIPVTGYHYQWMSRLANPVLGWIIGWISFTFLAIVV
CAVDYTIASTILPVLLNYESTATIAWLITAGVLLIQFLLVAFSTPWAERVNNSFVTLELIGMVALTVLLLVVAAIRGDMD
FGNLFSKGAVPAEGFWSFGDWTSAGPWMLGFLLGAFTIVGFESAANLAEETHDPERVVPRAMCQAVLASGVLGFLFLVAV
TLAAGDPIALAESGTPIADVIESTLGSVVATLLLLMVVLAIFACGLVIMITGVRLTWAMSRDKRFPGWQQWDQISSRFHT
PFKAAVLYFVVANLILAIFSRSETALFTLFGAATLLPAVMYASTVVLYLIKRKSLPANGKFDLGAWEIPVVAVAVVWLAF
ELALFRDSSFKEAWSYVIVMVVIGALYLGYLLATRGRHGLSMPDMHSIDAELDREAAKD
>Mature_538_residues
AKENRSPRRVNALLPGLTMMWLTPILRFNHMVYTNSGGTMSGPVPGDGDAAELAQFGYSQSLERRTGKFASFAVAFAFVS
IATGIFTTYGSVLNSSGPIGIWTWPIAVVGQLAVAFVLGALASRIPVTGYHYQWMSRLANPVLGWIIGWISFTFLAIVVC
AVDYTIASTILPVLLNYESTATIAWLITAGVLLIQFLLVAFSTPWAERVNNSFVTLELIGMVALTVLLLVVAAIRGDMDF
GNLFSKGAVPAEGFWSFGDWTSAGPWMLGFLLGAFTIVGFESAANLAEETHDPERVVPRAMCQAVLASGVLGFLFLVAVT
LAAGDPIALAESGTPIADVIESTLGSVVATLLLLMVVLAIFACGLVIMITGVRLTWAMSRDKRFPGWQQWDQISSRFHTP
FKAAVLYFVVANLILAIFSRSETALFTLFGAATLLPAVMYASTVVLYLIKRKSLPANGKFDLGAWEIPVVAVAVVWLAFE
LALFRDSSFKEAWSYVIVMVVIGALYLGYLLATRGRHGLSMPDMHSIDAELDREAAKD

Specific function: Probable Amino-Acid Or Metabolite Transport Protein. [C]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081869, Length=406, Percent_Identity=22.9064039408867, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082023, Length=289, Percent_Identity=24.9134948096886, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319991, Length=450, Percent_Identity=25.3333333333333, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321361, Length=486, Percent_Identity=23.2510288065844, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6322674, Length=292, Percent_Identity=26.3698630136986, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 58285; Mature: 58154

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKENRSPRRVNALLPGLTMMWLTPILRFNHMVYTNSGGTMSGPVPGDGDAAELAQFGYS
CCCCCCCCHHHHHHHCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHCHH
QSLERRTGKFASFAVAFAFVSIATGIFTTYGSVLNSSGPIGIWTWPIAVVGQLAVAFVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHH
ALASRIPVTGYHYQWMSRLANPVLGWIIGWISFTFLAIVVCAVDYTIASTILPVLLNYES
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TATIAWLITAGVLLIQFLLVAFSTPWAERVNNSFVTLELIGMVALTVLLLVVAAIRGDMD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
FGNLFSKGAVPAEGFWSFGDWTSAGPWMLGFLLGAFTIVGFESAANLAEETHDPERVVPR
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AMCQAVLASGVLGFLFLVAVTLAAGDPIALAESGTPIADVIESTLGSVVATLLLLMVVLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IFACGLVIMITGVRLTWAMSRDKRFPGWQQWDQISSRFHTPFKAAVLYFVVANLILAIFS
HHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
RSETALFTLFGAATLLPAVMYASTVVLYLIKRKSLPANGKFDLGAWEIPVVAVAVVWLAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ELALFRDSSFKEAWSYVIVMVVIGALYLGYLLATRGRHGLSMPDMHSIDAELDREAAKD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
AKENRSPRRVNALLPGLTMMWLTPILRFNHMVYTNSGGTMSGPVPGDGDAAELAQFGYS
CCCCCCCHHHHHHHCHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHCHH
QSLERRTGKFASFAVAFAFVSIATGIFTTYGSVLNSSGPIGIWTWPIAVVGQLAVAFVLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHH
ALASRIPVTGYHYQWMSRLANPVLGWIIGWISFTFLAIVVCAVDYTIASTILPVLLNYES
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TATIAWLITAGVLLIQFLLVAFSTPWAERVNNSFVTLELIGMVALTVLLLVVAAIRGDMD
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
FGNLFSKGAVPAEGFWSFGDWTSAGPWMLGFLLGAFTIVGFESAANLAEETHDPERVVPR
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
AMCQAVLASGVLGFLFLVAVTLAAGDPIALAESGTPIADVIESTLGSVVATLLLLMVVLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IFACGLVIMITGVRLTWAMSRDKRFPGWQQWDQISSRFHTPFKAAVLYFVVANLILAIFS
HHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
RSETALFTLFGAATLLPAVMYASTVVLYLIKRKSLPANGKFDLGAWEIPVVAVAVVWLAF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
ELALFRDSSFKEAWSYVIVMVVIGALYLGYLLATRGRHGLSMPDMHSIDAELDREAAKD
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]