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The map label for this gene is ytfL [C]

Identifier: 119869572

GI number: 119869572

Start: 3732989

End: 3734365

Strand: Direct

Name: ytfL [C]

Synonym: Mkms_3540

Alternate gene names: 119869572

Gene position: 3732989-3734365 (Clockwise)

Preceding gene: 119869571

Following gene: 119869573

Centisome position: 65.07

GC content: 67.54

Gene sequence:

>1377_bases
ATGTTGACCGCCGTCGTCGGAATTCTCGTAGGTTTTCTCGTCGTCTTGGCGATCACAGCGTTGACCGGATACTTCGTCGC
GCAGGAATTCGCCTACATGGCGGTGGACCGGTCACGGCTCAAGGCCCGCGCTGAGGCGGGCGACCACGCAGCCGCCCGCG
CGCTGACCGTCACCCGCCGCACTTCGTTCATGCTGTCGGGTGCCCAATTGGGCATCACGGTCACGGGACTGCTGGTCGGA
TACGTCGCCGAACCGCTGATCGGGCGCGGTCTGGAAACACTGCTCGGCGGTGCCGGGATCCCGACCGCGGTGGCTGTCGG
CATCGGCGGTCTCGTCGCAATCGCGGTCTCGACGGTCGTGCAGATGGTCTTCGGAGAACTCTTCCCGAAGAACCTGGCGA
TCGCCCGCCCCGAGCCGCTGGCCCGCTGGCTGGCGTTGTCGACAACGATCTATCTCAAGCTGTTCGGCTGGCTCATCTGG
CTGTTCGACCAGTCGTCGAACATGCTGCTGCGGCTTCTGCGCATCGAACCGGTGCATGACGTCGAGCATTCGGCGACGCC
GCGGGACCTCGAACACATCGTCGCCGCTTCCCGCGATGCCGGGGAGATCCCGCGGGAACTCTCCGCCCTGCTGGACCGTA
TCCTCGACTTCCCCACCAGCACCGCCGAACACGCGATGATCCCGCGTTCGCGCGTCGACGTGGTCCGCGCCGACGAAGCC
GTGCCGGATGTGCTGGAGCGCATGGCCCGCGGGCACACCCGCTATCCCGTCACCGGTTCCGGCCCTGACGACGTCATCGG
CGTGATCGACCTACACGACCTGCTCGGCCCCTCTACCCAGTCCACAAGCGGCACCGCCGGTGCGCGCTGCCGCCCGGCCG
TGGTCGTCCCGGAGACGCTCCCGCTGCCAAACGTGGTGCGCGAATTGGCTCAGACCGGTGACGAGATGGCGATCGTCATC
GACGAATACGGCGGGTTCGCCGGAATCGTCACCGTCGAGGATCTGGCCGAGGAACTCGTCGGCGAGATCGACGACGAACA
CGACACCGAATCGACGGCGGACATCGTCGCCCGGGACGGCGGCTGGCTGCTCGCCGGCGATCTACCACTCGACGAGGCCG
AACGCACCCTCGGGCTGACGCTGCCGGAAGGCGACTACGAAACGGTCGCGGGCATGGTCATCGCACACGCGGCCGGCCTA
CCCGACGCCGGGGACACCGTCGTCATCGAATTGCCCAGCGACAATGCGGATCTGCTCAACGACGGCCCTGCGCCGGCGCG
GCAGATCGTCGCGGAGGTGCGGGCCGTCGACCGGCGGGTACCGTCGCGTGTGTTGGTCACCGTCGACACCCGCACGGAGG
GGGGCGACGATGAATAG

Upstream 100 bases:

>100_bases
CACAGCACTCTCCCAGCGTCGGTACTCTGGGTGCCGACGGACTATCCGCCCACCTACCGAGCAAGGACTCGATGCCCCCT
CTCAGACCCAAGGCGGTCAC

Downstream 100 bases:

>100_bases
CCCGTGGGCGGTCGTGGCGATCACCGTCGGGCTCATCAGCCTCAGCGCGTTCTTCGTCGCCGTGGAGTTCGCGTTGATCG
CCGCACGCCGCAGCCGGCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MLTAVVGILVGFLVVLAITALTGYFVAQEFAYMAVDRSRLKARAEAGDHAAARALTVTRRTSFMLSGAQLGITVTGLLVG
YVAEPLIGRGLETLLGGAGIPTAVAVGIGGLVAIAVSTVVQMVFGELFPKNLAIARPEPLARWLALSTTIYLKLFGWLIW
LFDQSSNMLLRLLRIEPVHDVEHSATPRDLEHIVAASRDAGEIPRELSALLDRILDFPTSTAEHAMIPRSRVDVVRADEA
VPDVLERMARGHTRYPVTGSGPDDVIGVIDLHDLLGPSTQSTSGTAGARCRPAVVVPETLPLPNVVRELAQTGDEMAIVI
DEYGGFAGIVTVEDLAEELVGEIDDEHDTESTADIVARDGGWLLAGDLPLDEAERTLGLTLPEGDYETVAGMVIAHAAGL
PDAGDTVVIELPSDNADLLNDGPAPARQIVAEVRAVDRRVPSRVLVTVDTRTEGGDDE

Sequences:

>Translated_458_residues
MLTAVVGILVGFLVVLAITALTGYFVAQEFAYMAVDRSRLKARAEAGDHAAARALTVTRRTSFMLSGAQLGITVTGLLVG
YVAEPLIGRGLETLLGGAGIPTAVAVGIGGLVAIAVSTVVQMVFGELFPKNLAIARPEPLARWLALSTTIYLKLFGWLIW
LFDQSSNMLLRLLRIEPVHDVEHSATPRDLEHIVAASRDAGEIPRELSALLDRILDFPTSTAEHAMIPRSRVDVVRADEA
VPDVLERMARGHTRYPVTGSGPDDVIGVIDLHDLLGPSTQSTSGTAGARCRPAVVVPETLPLPNVVRELAQTGDEMAIVI
DEYGGFAGIVTVEDLAEELVGEIDDEHDTESTADIVARDGGWLLAGDLPLDEAERTLGLTLPEGDYETVAGMVIAHAAGL
PDAGDTVVIELPSDNADLLNDGPAPARQIVAEVRAVDRRVPSRVLVTVDTRTEGGDDE
>Mature_458_residues
MLTAVVGILVGFLVVLAITALTGYFVAQEFAYMAVDRSRLKARAEAGDHAAARALTVTRRTSFMLSGAQLGITVTGLLVG
YVAEPLIGRGLETLLGGAGIPTAVAVGIGGLVAIAVSTVVQMVFGELFPKNLAIARPEPLARWLALSTTIYLKLFGWLIW
LFDQSSNMLLRLLRIEPVHDVEHSATPRDLEHIVAASRDAGEIPRELSALLDRILDFPTSTAEHAMIPRSRVDVVRADEA
VPDVLERMARGHTRYPVTGSGPDDVIGVIDLHDLLGPSTQSTSGTAGARCRPAVVVPETLPLPNVVRELAQTGDEMAIVI
DEYGGFAGIVTVEDLAEELVGEIDDEHDTESTADIVARDGGWLLAGDLPLDEAERTLGLTLPEGDYETVAGMVIAHAAGL
PDAGDTVVIELPSDNADLLNDGPAPARQIVAEVRAVDRRVPSRVLVTVDTRTEGGDDE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=386, Percent_Identity=30.3108808290155, Blast_Score=177, Evalue=2e-44,
Organism=Escherichia coli, GI1790664, Length=406, Percent_Identity=24.6305418719212, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI145693175, Length=392, Percent_Identity=26.530612244898, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI87082033, Length=212, Percent_Identity=30.6603773584906, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786879, Length=232, Percent_Identity=29.3103448275862, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1788119, Length=321, Percent_Identity=25.2336448598131, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48639; Mature: 48639

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTAVVGILVGFLVVLAITALTGYFVAQEFAYMAVDRSRLKARAEAGDHAAARALTVTRR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TSFMLSGAQLGITVTGLLVGYVAEPLIGRGLETLLGGAGIPTAVAVGIGGLVAIAVSTVV
HHHEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QMVFGELFPKNLAIARPEPLARWLALSTTIYLKLFGWLIWLFDQSSNMLLRLLRIEPVHD
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
VEHSATPRDLEHIVAASRDAGEIPRELSALLDRILDFPTSTAEHAMIPRSRVDVVRADEA
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
VPDVLERMARGHTRYPVTGSGPDDVIGVIDLHDLLGPSTQSTSGTAGARCRPAVVVPETL
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCEEECCCCC
PLPNVVRELAQTGDEMAIVIDEYGGFAGIVTVEDLAEELVGEIDDEHDTESTADIVARDG
CCHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHHHEEECC
GWLLAGDLPLDEAERTLGLTLPEGDYETVAGMVIAHAAGLPDAGDTVVIELPSDNADLLN
CEEEECCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
DGPAPARQIVAEVRAVDRRVPSRVLVTVDTRTEGGDDE
CCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MLTAVVGILVGFLVVLAITALTGYFVAQEFAYMAVDRSRLKARAEAGDHAAARALTVTRR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TSFMLSGAQLGITVTGLLVGYVAEPLIGRGLETLLGGAGIPTAVAVGIGGLVAIAVSTVV
HHHEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
QMVFGELFPKNLAIARPEPLARWLALSTTIYLKLFGWLIWLFDQSSNMLLRLLRIEPVHD
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCC
VEHSATPRDLEHIVAASRDAGEIPRELSALLDRILDFPTSTAEHAMIPRSRVDVVRADEA
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHH
VPDVLERMARGHTRYPVTGSGPDDVIGVIDLHDLLGPSTQSTSGTAGARCRPAVVVPETL
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCCCEEECCCCC
PLPNVVRELAQTGDEMAIVIDEYGGFAGIVTVEDLAEELVGEIDDEHDTESTADIVARDG
CCHHHHHHHHHCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHCCCCCCCCHHHHHEEECC
GWLLAGDLPLDEAERTLGLTLPEGDYETVAGMVIAHAAGLPDAGDTVVIELPSDNADLLN
CEEEECCCCCCHHHHHEECCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCC
DGPAPARQIVAEVRAVDRRVPSRVLVTVDTRTEGGDDE
CCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]