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The map label for this gene is fur [H]

Identifier: 119869542

GI number: 119869542

Start: 3687417

End: 3687812

Strand: Direct

Name: fur [H]

Synonym: Mkms_3510

Alternate gene names: 119869542

Gene position: 3687417-3687812 (Clockwise)

Preceding gene: 119869541

Following gene: 119869546

Centisome position: 64.27

GC content: 71.46

Gene sequence:

>396_bases
GTGAGCCCGGCCCCGGTCCGCGCGACGCGGCAGCGGGCGGCGATCGCCGACCTGCTCGACGGACTCGACGAGTTCCGCTC
GGCCCAGGAGCTGCACGACGCGCTCAAGCGCCGCGGTGAGGGCATCGGGTTGACGACGGTATACCGCACCCTGCAGTCGA
TGGCGGAGTCCGGGCTGGTCGACGTGCTCCGCACCGACACCGGCGAGTCGGTCTACCGCCGCTGCTCGGCCGACCACCAC
CATCACCTGGTGTGCCGCGCGTGCGGCGCGGCCGTCGAGATCCAGGGCGGTCAGGTCGAGACGTGGGCCGCCGACATCGC
CCGCGAGCACGGATTCTCCGACGTCAGCCACACCATCGAGATCTTCGGTCTGTGCGGGGACTGCTCAGCCCGTTAG

Upstream 100 bases:

>100_bases
CCAGCGAGCGGTCCGGCCGCGAGGTGCTCTACCGGCTCGTCGACGCGCATCTGGTGCACATCGTCACCGACGCCGTCGCC
CACGCCGGTGAGGACGTCCG

Downstream 100 bases:

>100_bases
CGCCCGGCGGATGTCGGCGCCGGCGCTGAGCACCAGCAGGATCAGCGTGCGCAACGCGTCGTCGGTGAGGCCGGCGGCCG
GAAAGTTGTAGCGCAGCAAC

Product: zinc uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MSPAPVRATRQRAAIADLLDGLDEFRSAQELHDALKRRGEGIGLTTVYRTLQSMAESGLVDVLRTDTGESVYRRCSADHH
HHLVCRACGAAVEIQGGQVETWAADIAREHGFSDVSHTIEIFGLCGDCSAR

Sequences:

>Translated_131_residues
MSPAPVRATRQRAAIADLLDGLDEFRSAQELHDALKRRGEGIGLTTVYRTLQSMAESGLVDVLRTDTGESVYRRCSADHH
HHLVCRACGAAVEIQGGQVETWAADIAREHGFSDVSHTIEIFGLCGDCSAR
>Mature_130_residues
SPAPVRATRQRAAIADLLDGLDEFRSAQELHDALKRRGEGIGLTTVYRTLQSMAESGLVDVLRTDTGESVYRRCSADHHH
HLVCRACGAAVEIQGGQVETWAADIAREHGFSDVSHTIEIFGLCGDCSAR

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. Regulates the expression of the fbp protein [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=131, Percent_Identity=33.587786259542, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 14247; Mature: 14116

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAPVRATRQRAAIADLLDGLDEFRSAQELHDALKRRGEGIGLTTVYRTLQSMAESGLV
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHH
DVLRTDTGESVYRRCSADHHHHLVCRACGAAVEIQGGQVETWAADIAREHGFSDVSHTIE
HHHHCCCCHHHHHHHCCCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHH
IFGLCGDCSAR
HHHCCCCCCCC
>Mature Secondary Structure 
SPAPVRATRQRAAIADLLDGLDEFRSAQELHDALKRRGEGIGLTTVYRTLQSMAESGLV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHH
DVLRTDTGESVYRRCSADHHHHLVCRACGAAVEIQGGQVETWAADIAREHGFSDVSHTIE
HHHHCCCCHHHHHHHCCCCHHHHHHHHHCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHH
IFGLCGDCSAR
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8406856 [H]