| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is fabG [H]
Identifier: 119869489
GI number: 119869489
Start: 3625460
End: 3626200
Strand: Direct
Name: fabG [H]
Synonym: Mkms_3457
Alternate gene names: 119869489
Gene position: 3625460-3626200 (Clockwise)
Preceding gene: 119869488
Following gene: 119869490
Centisome position: 63.19
GC content: 68.69
Gene sequence:
>741_bases ATGACACAGCTGAGCGGCAAGGTGGCGTTGGTGACGGGCGCGTCGTCGGGGTTGGGTGCGGCGACGGCGAAAGTGTTCGC CGAGCGCGGTGCGACGGTGTTCGGGATCTCCCGCGACGCCGACCGGATGGCGTCGGTGTTCGCCGACGTGCCCGGCGGGA CGTACGCGTCGGTCGACATCACCTCCCCCGAGGCCTGCCGCCGAGCCGTCGACGACTGCGTCGCGAAGTTCGGCAGGCTC GACGTGCTGGCGAACATCGCCGGCTACCACCAGATGCGGCATACCCCGACGATGTCCGATGCCGACTGGGACCACGACCT CGCCGTCAACCTCAACGGCCCGTTCTTCCTGTGCCGCGCCGCGTTACCGCACCTGCTCGAGACCGGCGGCAGCATCGTCA ACGTCGCCTCCATCGCGGGTGTCGAGGGTGAGGTGTACTCGGCGGGCTACTGTGCGGCCAAACACGGTCTGGTCGGTCTG ACGCGCGCACTGGCCATCGAGTTCACCGCGGACCGGGTGCGGATCAACGCCGTCTGCCCCGGCGGCATGGTCACCCCGCA GACGACGGAGTTCTCCGCACCCGATCAGGCGGACTGGAACCTGATCATGCGCATCGCCGCACCCCGCGGGATGATGGATG TCGCCGACGTCGCCAAGACCATCGCGTTTCTGGCCAGCGATGACGCCGCGGCGGTGCACGGCGCGGTGTACGTGGTGGAC AACGGGAAGACGGCAGGATGA
Upstream 100 bases:
>100_bases ACGGATTTGTTCGCCGCCCCCGAGCAGCCGTACACCCGGGACCTGCTGGCGGCCGTGCCTCCCGCCCGGCCCCGTGCGTC GGCGTGAGACAGTCGTCGCC
Downstream 100 bases:
>100_bases CGCGACTCCCAGGTGTGGTGCGGTCGAAGGCGACCCGAGCGAGCGCAGGGGTGGCCAGGTCGGTGGGGACCCTCAACAGC GCAGGCGTCTCGGCGTCCGT
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 246; Mature: 245
Protein sequence:
>246_residues MTQLSGKVALVTGASSGLGAATAKVFAERGATVFGISRDADRMASVFADVPGGTYASVDITSPEACRRAVDDCVAKFGRL DVLANIAGYHQMRHTPTMSDADWDHDLAVNLNGPFFLCRAALPHLLETGGSIVNVASIAGVEGEVYSAGYCAAKHGLVGL TRALAIEFTADRVRINAVCPGGMVTPQTTEFSAPDQADWNLIMRIAAPRGMMDVADVAKTIAFLASDDAAAVHGAVYVVD NGKTAG
Sequences:
>Translated_246_residues MTQLSGKVALVTGASSGLGAATAKVFAERGATVFGISRDADRMASVFADVPGGTYASVDITSPEACRRAVDDCVAKFGRL DVLANIAGYHQMRHTPTMSDADWDHDLAVNLNGPFFLCRAALPHLLETGGSIVNVASIAGVEGEVYSAGYCAAKHGLVGL TRALAIEFTADRVRINAVCPGGMVTPQTTEFSAPDQADWNLIMRIAAPRGMMDVADVAKTIAFLASDDAAAVHGAVYVVD NGKTAG >Mature_245_residues TQLSGKVALVTGASSGLGAATAKVFAERGATVFGISRDADRMASVFADVPGGTYASVDITSPEACRRAVDDCVAKFGRLD VLANIAGYHQMRHTPTMSDADWDHDLAVNLNGPFFLCRAALPHLLETGGSIVNVASIAGVEGEVYSAGYCAAKHGLVGLT RALAIEFTADRVRINAVCPGGMVTPQTTEFSAPDQADWNLIMRIAAPRGMMDVADVAKTIAFLASDDAAAVHGAVYVVDN GKTAG
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=259, Percent_Identity=35.1351351351351, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI66933014, Length=248, Percent_Identity=30.241935483871, Blast_Score=107, Evalue=8e-24, Organism=Homo sapiens, GI59889578, Length=208, Percent_Identity=30.2884615384615, Blast_Score=102, Evalue=2e-22, Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=31.9327731092437, Blast_Score=100, Evalue=8e-22, Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI4504505, Length=191, Percent_Identity=36.6492146596859, Blast_Score=99, Evalue=5e-21, Organism=Homo sapiens, GI31542939, Length=258, Percent_Identity=29.0697674418605, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI5031737, Length=236, Percent_Identity=30.0847457627119, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI10190704, Length=245, Percent_Identity=27.3469387755102, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=29.1497975708502, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4758504, Length=244, Percent_Identity=29.9180327868852, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI7705925, Length=243, Percent_Identity=29.6296296296296, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI33667109, Length=183, Percent_Identity=32.2404371584699, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=31.25, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=31.3953488372093, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI83715985, Length=188, Percent_Identity=31.9148936170213, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI210032110, Length=234, Percent_Identity=26.4957264957265, Blast_Score=72, Evalue=3e-13, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=29.2817679558011, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=24.8995983935743, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI166795268, Length=227, Percent_Identity=30.3964757709251, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=32.520325203252, Blast_Score=123, Evalue=1e-29, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=32.5102880658436, Blast_Score=121, Evalue=4e-29, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=33.0708661417323, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=31.0483870967742, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1786812, Length=251, Percent_Identity=32.2709163346614, Blast_Score=99, Evalue=4e-22, Organism=Escherichia coli, GI1788459, Length=245, Percent_Identity=27.3469387755102, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=29.2307692307692, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1787526, Length=255, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI2367365, Length=244, Percent_Identity=30.7377049180328, Blast_Score=78, Evalue=4e-16, Organism=Escherichia coli, GI1790717, Length=245, Percent_Identity=26.530612244898, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1787905, Length=249, Percent_Identity=27.710843373494, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789378, Length=265, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=2e-14, Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=30.46875, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1787820, Length=179, Percent_Identity=27.3743016759777, Blast_Score=64, Evalue=8e-12, Organism=Caenorhabditis elegans, GI71994600, Length=253, Percent_Identity=33.9920948616601, Blast_Score=118, Evalue=2e-27, Organism=Caenorhabditis elegans, GI71994604, Length=249, Percent_Identity=34.136546184739, Blast_Score=116, Evalue=1e-26, Organism=Caenorhabditis elegans, GI17560332, Length=264, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=32.319391634981, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=31.4285714285714, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=32.9588014981273, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17561402, Length=254, Percent_Identity=31.8897637795276, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562906, Length=263, Percent_Identity=33.4600760456274, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560220, Length=243, Percent_Identity=32.5102880658436, Blast_Score=103, Evalue=8e-23, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=31.5589353612167, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17563726, Length=241, Percent_Identity=30.7053941908714, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=30.4878048780488, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=28.7449392712551, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538182, Length=217, Percent_Identity=32.258064516129, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=29.5019157088123, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=30.0751879699248, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17562904, Length=261, Percent_Identity=29.8850574712644, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=30.7407407407407, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=30.2583025830258, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=29.8507462686567, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=30.2681992337165, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538486, Length=193, Percent_Identity=33.160621761658, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17565030, Length=263, Percent_Identity=31.9391634980989, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI193203117, Length=220, Percent_Identity=29.5454545454545, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17551412, Length=191, Percent_Identity=29.8429319371728, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI193203115, Length=215, Percent_Identity=29.7674418604651, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=27.1604938271605, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17564282, Length=185, Percent_Identity=30.8108108108108, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=27.2, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI17508895, Length=186, Percent_Identity=28.494623655914, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=26, Blast_Score=68, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=186, Percent_Identity=32.7956989247312, Blast_Score=86, Evalue=8e-18, Organism=Saccharomyces cerevisiae, GI6322067, Length=216, Percent_Identity=28.7037037037037, Blast_Score=70, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=248, Percent_Identity=25.8064516129032, Blast_Score=66, Evalue=5e-12, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=36.1788617886179, Blast_Score=131, Evalue=3e-31, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=6e-26, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=31.7073170731707, Blast_Score=110, Evalue=7e-25, Organism=Drosophila melanogaster, GI21357041, Length=254, Percent_Identity=31.496062992126, Blast_Score=107, Evalue=8e-24, Organism=Drosophila melanogaster, GI21355319, Length=252, Percent_Identity=30.1587301587302, Blast_Score=105, Evalue=2e-23, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=30.4347826086957, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=30.5785123966942, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI18859837, Length=214, Percent_Identity=33.1775700934579, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI17737361, Length=234, Percent_Identity=29.0598290598291, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI24665243, Length=251, Percent_Identity=27.0916334661355, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI221331218, Length=251, Percent_Identity=27.0916334661355, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24665247, Length=252, Percent_Identity=26.5873015873016, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI221331216, Length=252, Percent_Identity=26.5873015873016, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI21357673, Length=224, Percent_Identity=25.8928571428571, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24641232, Length=197, Percent_Identity=29.4416243654822, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=32.4427480916031, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI21358495, Length=250, Percent_Identity=26.4, Blast_Score=67, Evalue=7e-12, Organism=Drosophila melanogaster, GI22024069, Length=199, Percent_Identity=32.6633165829146, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI19921754, Length=205, Percent_Identity=30.7317073170732, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25519; Mature: 25388
Theoretical pI: Translated: 5.24; Mature: 5.24
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 3.3 %Met (Translated Protein) 5.3 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 2.9 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTQLSGKVALVTGASSGLGAATAKVFAERGATVFGISRDADRMASVFADVPGGTYASVDI CCCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEC TSPEACRRAVDDCVAKFGRLDVLANIAGYHQMRHTPTMSDADWDHDLAVNLNGPFFLCRA CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHH ALPHLLETGGSIVNVASIAGVEGEVYSAGYCAAKHGLVGLTRALAIEFTADRVRINAVCP HHHHHHHCCCCEEEEHHHCCCCCCEEECCHHHHHCCHHHHHHHEEEEEEECEEEEEEECC GGMVTPQTTEFSAPDQADWNLIMRIAAPRGMMDVADVAKTIAFLASDDAAAVHGAVYVVD CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEE NGKTAG CCCCCC >Mature Secondary Structure TQLSGKVALVTGASSGLGAATAKVFAERGATVFGISRDADRMASVFADVPGGTYASVDI CCCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCCCEEEEEC TSPEACRRAVDDCVAKFGRLDVLANIAGYHQMRHTPTMSDADWDHDLAVNLNGPFFLCRA CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHH ALPHLLETGGSIVNVASIAGVEGEVYSAGYCAAKHGLVGLTRALAIEFTADRVRINAVCP HHHHHHHCCCCEEEEHHHCCCCCCEEECCHHHHHCCHHHHHHHEEEEEEECEEEEEEECC GGMVTPQTTEFSAPDQADWNLIMRIAAPRGMMDVADVAKTIAFLASDDAAAVHGAVYVVD CCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEE NGKTAG CCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 10360571 [H]