Click here to switch to the map view.

The map label for this gene is dppA [H]

Identifier: 119869485

GI number: 119869485

Start: 3620419

End: 3621957

Strand: Direct

Name: dppA [H]

Synonym: Mkms_3453

Alternate gene names: 119869485

Gene position: 3620419-3621957 (Clockwise)

Preceding gene: 119869483

Following gene: 119869486

Centisome position: 63.1

GC content: 67.9

Gene sequence:

>1539_bases
ATGCGGCGTGACGCGGTGCAGGCTGCCGGCCTGGCCCTGATCGTGGCGCTGCTGCTGGCGGTCACGGGCTGTTCCACCGG
AGAACGCGTAGACCTCGGTGACGCCACCTCGGGCAATCTCGTAGCCGCGATCGCGGGCGAACCCGACCAACTCGACCCGC
ACAAGACCAGCGCGTACTTCTCGTTCGAGGTGCTCGAGAACGTGTTCGACACCCTGGTCGAACCCGACGCCGCCCTCGAG
ATGCGCCCGGCGCTCGCCGAGAGCTGGGAGGTCAGCCCCGACCAGCGGGTGTGGACGTTCCACCTGCGGCGCGGCGTGAC
CTTCCACGACGGCTCGCCGTTCACCGCCGACGACGTCGTCTACTCCTACCGCCGCATCATCGACGAGGAACTCACCAACG
TCGACAAGTTCAGCGCCGTCACCGACGTCACCGCCGTCGACCCCGCCACCGTGCGCATCACCGTCGACAAACCCACCCCG
AACCTGCTGACCAACCTCGGCGGGTTCAAGGGGATGGCGATCGTGTCGCGGGCCAACGTCGAGAGCGGACGCATCGCCAC
CCATCCCGTCGGGACCGGACCGTTCTCGTTCGCCGGCGCCACCAGCGGTGACTCGATCACGTTGCGCGCCAACCCCTCGT
TCTGGGGTGGACCGCCCCGCATCTCGGGGGTCACGTTCCGGTTCATCTCCGAACCGTCGACGGCGTTGTCGGCCCTGCAG
GCAGGCGAGATCGACTGGACCGACTCGGTTCCCCCGCAACGGGTTTCGCAGCTGCGTGACGACGAGTCCCTGCGCCTCGC
CGTCACACCGAGCAATGACTACTGGTATCTGGCGCTCAACGAGGCGCGTGCCCCGTGGAACGACGTGCGGGTGCGCCAGG
CGATCGCCTACGGCATCGACCGCGAGGCGATCGTCGCCGCCACGAGCTACGGCACCGCGGCCGAGAATCAGCTCGCGATC
CCCGAGGGCAACCCCTGGTACACCCCGTACGACCGGTACTCCGCCGATCTCGAGAAGGCCAGGAGCCTGCTGGCCGAGGC
GAACGCCGAACCGGACCGGCTCGACATGCTGGTCACCAGCGAGTATCCCGAGACGGTCACCGCCGCGCAGATCATCGCCG
ACAACCTCGCCCCGCTGGGGATCACGGTCGACATCCGCACCGTGGACTTCGCCACCTGGCTCGACGAACAGAACAACGGC
AACTTCGACATGCTGATGATGGGTTGGCTCGGCAACATCGACCCCGACGACTTCTACTACGCCCAGCACCACACGAACGG
CACCAGCAACGCCCAGAAGTTCTCCGACCCGGAGGTGGACCGCCTGCTCGACGCCGGCCGCGTGGAGACCGACCGCGACG
CGCGCCACGACGTCTACGCCAAGGCCGCCACCCGCATCGCCGACGAGGTCAGCTACATCTACCTCTACAACCCGTCGGTC
ATCCAGGCCTGGACCCCGGCCCTGTCGGGATACGAGGCACGCCGCGACGGTGCGGTCCGCTTCCGCGACGCCGTCCTCGG
TGAGGACGAAAGCTCATGA

Upstream 100 bases:

>100_bases
GCCTCCCGTGAAGTCACCGGTTCACCGCTTCGGCGTTTGCGGGGACGACCGCGTGGGGTAAGAAGCGGGGAGGTGCCCGA
TTGATCTTGAGGTGGTCGTG

Downstream 100 bases:

>100_bases
CGGCGTTGCTCACCCACCCCGTCGTACGCTTCCTCGCCCGGCGGATCGCCTATTCGCTGGTGGTGCTGATCGGTGTGCTG
GTCGTGGTGTTCGCACTCGT

Product: extracellular solute-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MRRDAVQAAGLALIVALLLAVTGCSTGERVDLGDATSGNLVAAIAGEPDQLDPHKTSAYFSFEVLENVFDTLVEPDAALE
MRPALAESWEVSPDQRVWTFHLRRGVTFHDGSPFTADDVVYSYRRIIDEELTNVDKFSAVTDVTAVDPATVRITVDKPTP
NLLTNLGGFKGMAIVSRANVESGRIATHPVGTGPFSFAGATSGDSITLRANPSFWGGPPRISGVTFRFISEPSTALSALQ
AGEIDWTDSVPPQRVSQLRDDESLRLAVTPSNDYWYLALNEARAPWNDVRVRQAIAYGIDREAIVAATSYGTAAENQLAI
PEGNPWYTPYDRYSADLEKARSLLAEANAEPDRLDMLVTSEYPETVTAAQIIADNLAPLGITVDIRTVDFATWLDEQNNG
NFDMLMMGWLGNIDPDDFYYAQHHTNGTSNAQKFSDPEVDRLLDAGRVETDRDARHDVYAKAATRIADEVSYIYLYNPSV
IQAWTPALSGYEARRDGAVRFRDAVLGEDESS

Sequences:

>Translated_512_residues
MRRDAVQAAGLALIVALLLAVTGCSTGERVDLGDATSGNLVAAIAGEPDQLDPHKTSAYFSFEVLENVFDTLVEPDAALE
MRPALAESWEVSPDQRVWTFHLRRGVTFHDGSPFTADDVVYSYRRIIDEELTNVDKFSAVTDVTAVDPATVRITVDKPTP
NLLTNLGGFKGMAIVSRANVESGRIATHPVGTGPFSFAGATSGDSITLRANPSFWGGPPRISGVTFRFISEPSTALSALQ
AGEIDWTDSVPPQRVSQLRDDESLRLAVTPSNDYWYLALNEARAPWNDVRVRQAIAYGIDREAIVAATSYGTAAENQLAI
PEGNPWYTPYDRYSADLEKARSLLAEANAEPDRLDMLVTSEYPETVTAAQIIADNLAPLGITVDIRTVDFATWLDEQNNG
NFDMLMMGWLGNIDPDDFYYAQHHTNGTSNAQKFSDPEVDRLLDAGRVETDRDARHDVYAKAATRIADEVSYIYLYNPSV
IQAWTPALSGYEARRDGAVRFRDAVLGEDESS
>Mature_512_residues
MRRDAVQAAGLALIVALLLAVTGCSTGERVDLGDATSGNLVAAIAGEPDQLDPHKTSAYFSFEVLENVFDTLVEPDAALE
MRPALAESWEVSPDQRVWTFHLRRGVTFHDGSPFTADDVVYSYRRIIDEELTNVDKFSAVTDVTAVDPATVRITVDKPTP
NLLTNLGGFKGMAIVSRANVESGRIATHPVGTGPFSFAGATSGDSITLRANPSFWGGPPRISGVTFRFISEPSTALSALQ
AGEIDWTDSVPPQRVSQLRDDESLRLAVTPSNDYWYLALNEARAPWNDVRVRQAIAYGIDREAIVAATSYGTAAENQLAI
PEGNPWYTPYDRYSADLEKARSLLAEANAEPDRLDMLVTSEYPETVTAAQIIADNLAPLGITVDIRTVDFATWLDEQNNG
NFDMLMMGWLGNIDPDDFYYAQHHTNGTSNAQKFSDPEVDRLLDAGRVETDRDARHDVYAKAATRIADEVSYIYLYNPSV
IQAWTPALSGYEARRDGAVRFRDAVLGEDESS

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=544, Percent_Identity=25.9191176470588, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI87081878, Length=519, Percent_Identity=29.0944123314065, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1787762, Length=472, Percent_Identity=27.5423728813559, Blast_Score=168, Evalue=7e-43,
Organism=Escherichia coli, GI1787052, Length=519, Percent_Identity=24.6628131021195, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1787495, Length=534, Percent_Identity=26.4044943820225, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1787551, Length=517, Percent_Identity=26.6924564796905, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1789397, Length=477, Percent_Identity=24.1090146750524, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789887, Length=465, Percent_Identity=25.3763440860215, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87082063, Length=454, Percent_Identity=23.3480176211454, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 56071; Mature: 56071

Theoretical pI: Translated: 4.24; Mature: 4.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRDAVQAAGLALIVALLLAVTGCSTGERVDLGDATSGNLVAAIAGEPDQLDPHKTSAYF
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCEE
SFEVLENVFDTLVEPDAALEMRPALAESWEVSPDQRVWTFHLRRGVTFHDGSPFTADDVV
HHHHHHHHHHHHCCCCCHHHCCHHHHHCCCCCCCCEEEEEEEECCCEEECCCCCCHHHHH
YSYRRIIDEELTNVDKFSAVTDVTAVDPATVRITVDKPTPNLLTNLGGFKGMAIVSRANV
HHHHHHHHHHHHCCHHHHHHHCEEECCCEEEEEEECCCCHHHHHHCCCCCCEEEEEECCC
ESGRIATHPVGTGPFSFAGATSGDSITLRANPSFWGGPPRISGVTFRFISEPSTALSALQ
CCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHH
AGEIDWTDSVPPQRVSQLRDDESLRLAVTPSNDYWYLALNEARAPWNDVRVRQAIAYGID
CCCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCC
REAIVAATSYGTAAENQLAIPEGNPWYTPYDRYSADLEKARSLLAEANAEPDRLDMLVTS
CCCEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
EYPETVTAAQIIADNLAPLGITVDIRTVDFATWLDEQNNGNFDMLMMGWLGNIDPDDFYY
CCCCHHHHHHHHHHCCCCEEEEEEEEEEEEEEHHCCCCCCCEEEEEEECCCCCCCCCEEE
AQHHTNGTSNAQKFSDPEVDRLLDAGRVETDRDARHDVYAKAATRIADEVSYIYLYNPSV
EEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCC
IQAWTPALSGYEARRDGAVRFRDAVLGEDESS
EEHHCCCCCCCCCCCCCCEEEEHHHCCCCCCC
>Mature Secondary Structure
MRRDAVQAAGLALIVALLLAVTGCSTGERVDLGDATSGNLVAAIAGEPDQLDPHKTSAYF
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEECCCCCCCCCCCCCCEE
SFEVLENVFDTLVEPDAALEMRPALAESWEVSPDQRVWTFHLRRGVTFHDGSPFTADDVV
HHHHHHHHHHHHCCCCCHHHCCHHHHHCCCCCCCCEEEEEEEECCCEEECCCCCCHHHHH
YSYRRIIDEELTNVDKFSAVTDVTAVDPATVRITVDKPTPNLLTNLGGFKGMAIVSRANV
HHHHHHHHHHHHCCHHHHHHHCEEECCCEEEEEEECCCCHHHHHHCCCCCCEEEEEECCC
ESGRIATHPVGTGPFSFAGATSGDSITLRANPSFWGGPPRISGVTFRFISEPSTALSALQ
CCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHHH
AGEIDWTDSVPPQRVSQLRDDESLRLAVTPSNDYWYLALNEARAPWNDVRVRQAIAYGID
CCCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCC
REAIVAATSYGTAAENQLAIPEGNPWYTPYDRYSADLEKARSLLAEANAEPDRLDMLVTS
CCCEEEEECCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
EYPETVTAAQIIADNLAPLGITVDIRTVDFATWLDEQNNGNFDMLMMGWLGNIDPDDFYY
CCCCHHHHHHHHHHCCCCEEEEEEEEEEEEEEHHCCCCCCCEEEEEEECCCCCCCCCEEE
AQHHTNGTSNAQKFSDPEVDRLLDAGRVETDRDARHDVYAKAATRIADEVSYIYLYNPSV
EEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCC
IQAWTPALSGYEARRDGAVRFRDAVLGEDESS
EEHHCCCCCCCCCCCCCCEEEEHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]