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The map label for this gene is ygcU [H]

Identifier: 119869468

GI number: 119869468

Start: 3604348

End: 3605925

Strand: Direct

Name: ygcU [H]

Synonym: Mkms_3436

Alternate gene names: 119869468

Gene position: 3604348-3605925 (Clockwise)

Preceding gene: 119869463

Following gene: 119869469

Centisome position: 62.82

GC content: 71.93

Gene sequence:

>1578_bases
ATGAAGTGGAACGCCTGGGGTGACCCGGATGCCGCCAAACCGCTGTCCGACGGCATCCGGGCGCTGCTCGAGCAGGCGCT
CGGCGTCACGGAAGGGGCGGCACCGCCCGCTCTCGAGGACGTGACCGTGCGCCCCTCTGCGCTGCCCGATGCCGACCGCG
ACGCACTCGGCGACATCGTCGGTGCGCCGTACTGCCTGGTCGACGACGCCGGCCGGCTGTTGCACGCGGGCGGCAAGTCC
ACCCTCGACCTGCTGCGCCGCCGCGACCGCGGTGAACAGGAGGCCCCCGACGCGGTCCTGCTGCCCGCCGACGAAGATCA
GATCGCCGCGATCCTCGAGTACTGCGGCGCGCAGCGGATCGCGGTGGTGCCGTTCGGCGGCGGCACGAGCGTGGTCGGGG
GTCTGGATCCGATCCGCGGCGACTTCACCGCGGTGGTGTCGCTCGACCTGCGGCGACTCGACCGGCTGCACTGGCTCGAC
GAGGTCTCCGGTGAGGCCGAACTGGGGGCCGGCGTCACCGGCCCGGACGCCGAACGGCTGCTCGGCGAACGCGGTTTCTC
CCTCGGACACTTCCCGCAGAGCTTCTGCTATGCGACCATCGGCGGCTTCGCCGCGACCCGGTCCTCGGGTCAGGACTCCG
CGGGTTACGGCCGCTTCGACGACATGGTGCGCGGCCTGCGCGCCGTCACTCCGGCCGGTGTCCTCGACATCGGCCGCGCT
CCCGCCTCGGCGGCAGGCCCGGACCTGCGGCAGCTCCTCGTCGGCTCCGAAGGGGCGTTCGGCGTGATCACCCGGGTACG
GCTGCGGGTGCACCCCGTTCCGGAGGTGACCCGATACGAGGCGTGGTCGTTCCCCGACTTCGCCACCGGCGCAACGGCTT
TGCGCGCAGTCACCCAGACCGGCAGCGGACCGACCGTGCTCCGACTGTCCGACGAGGCGGAGACCGGCGTCAACCTGGCG
ACCACCGAGGCCATCGGCGAGCAGACCATCACCGGCGGATGCCTGGCCGTCACGGTCTTCGAGGGCAGTGCAGCGCACGC
CGAGAGCAGACACGCCGAGACCCGCGCCCTGCTCGAAGAGCACGGCGGCAGGTCACTGGGCGAGGGACCCGCCAAGGCGT
GGGAGCACGGCCGGTTCGGGGCGCCGTATCTGCGTGACTCGCTGCTGTCCGCGGGGGCGCTGTGCGAGACGCTCGAAACC
GCCACCACGTGGTCGAACGTCCCGGCGCTCAAGACCGCGGTCACCGATGCGCTGACGGATGCGCTCGGCCGATCCGGGAC
GTCGGCGCTGGTGCTCTGCCACATCTCGCACGTCTATCCGACCGGCGCGTCGCTGTACTTCACGGTCGTCGCCGCCCAGC
GCGGCAACCCGATCGAGCAGTGGCGTGCCGCGAAAGCCGCTGCATCGGAAGCGATCATGCGCGCCGGCGGCACCATCACC
CACCACCACGCCGTCGGCGCCGACCACCGGCCCTGGATGCGCGACGAGGTCGGCGACCTGGGGGTGGAGATCCTGCGTGC
GGTCAAGGCGACCCTCGACCCGGCCGGAATCCTCAACCCGGGCAAGCTGATTCCATGA

Upstream 100 bases:

>100_bases
TCCTCCACCGATCGCGGACTGTCCTTACGGATTGACACCATGTGTAATACTGTAACGCATGTCCGCCGGATCGGAGCACC
CAGCAGCCCTTCTCCCCCCG

Downstream 100 bases:

>100_bases
CACGATGAGCCCGATGACCATCGGCCACGTCACGGTGCTGACGAACCCGCTGTCGGGCCACGGCAACGCCCCGCACGCCA
CCGAACGCGCCGTCGCCCGG

Product: alkylglycerone-phosphate synthase

Products: alkyl-glycerone 3-phosphate; long-chain acid anion

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MKWNAWGDPDAAKPLSDGIRALLEQALGVTEGAAPPALEDVTVRPSALPDADRDALGDIVGAPYCLVDDAGRLLHAGGKS
TLDLLRRRDRGEQEAPDAVLLPADEDQIAAILEYCGAQRIAVVPFGGGTSVVGGLDPIRGDFTAVVSLDLRRLDRLHWLD
EVSGEAELGAGVTGPDAERLLGERGFSLGHFPQSFCYATIGGFAATRSSGQDSAGYGRFDDMVRGLRAVTPAGVLDIGRA
PASAAGPDLRQLLVGSEGAFGVITRVRLRVHPVPEVTRYEAWSFPDFATGATALRAVTQTGSGPTVLRLSDEAETGVNLA
TTEAIGEQTITGGCLAVTVFEGSAAHAESRHAETRALLEEHGGRSLGEGPAKAWEHGRFGAPYLRDSLLSAGALCETLET
ATTWSNVPALKTAVTDALTDALGRSGTSALVLCHISHVYPTGASLYFTVVAAQRGNPIEQWRAAKAAASEAIMRAGGTIT
HHHAVGADHRPWMRDEVGDLGVEILRAVKATLDPAGILNPGKLIP

Sequences:

>Translated_525_residues
MKWNAWGDPDAAKPLSDGIRALLEQALGVTEGAAPPALEDVTVRPSALPDADRDALGDIVGAPYCLVDDAGRLLHAGGKS
TLDLLRRRDRGEQEAPDAVLLPADEDQIAAILEYCGAQRIAVVPFGGGTSVVGGLDPIRGDFTAVVSLDLRRLDRLHWLD
EVSGEAELGAGVTGPDAERLLGERGFSLGHFPQSFCYATIGGFAATRSSGQDSAGYGRFDDMVRGLRAVTPAGVLDIGRA
PASAAGPDLRQLLVGSEGAFGVITRVRLRVHPVPEVTRYEAWSFPDFATGATALRAVTQTGSGPTVLRLSDEAETGVNLA
TTEAIGEQTITGGCLAVTVFEGSAAHAESRHAETRALLEEHGGRSLGEGPAKAWEHGRFGAPYLRDSLLSAGALCETLET
ATTWSNVPALKTAVTDALTDALGRSGTSALVLCHISHVYPTGASLYFTVVAAQRGNPIEQWRAAKAAASEAIMRAGGTIT
HHHAVGADHRPWMRDEVGDLGVEILRAVKATLDPAGILNPGKLIP
>Mature_525_residues
MKWNAWGDPDAAKPLSDGIRALLEQALGVTEGAAPPALEDVTVRPSALPDADRDALGDIVGAPYCLVDDAGRLLHAGGKS
TLDLLRRRDRGEQEAPDAVLLPADEDQIAAILEYCGAQRIAVVPFGGGTSVVGGLDPIRGDFTAVVSLDLRRLDRLHWLD
EVSGEAELGAGVTGPDAERLLGERGFSLGHFPQSFCYATIGGFAATRSSGQDSAGYGRFDDMVRGLRAVTPAGVLDIGRA
PASAAGPDLRQLLVGSEGAFGVITRVRLRVHPVPEVTRYEAWSFPDFATGATALRAVTQTGSGPTVLRLSDEAETGVNLA
TTEAIGEQTITGGCLAVTVFEGSAAHAESRHAETRALLEEHGGRSLGEGPAKAWEHGRFGAPYLRDSLLSAGALCETLET
ATTWSNVPALKTAVTDALTDALGRSGTSALVLCHISHVYPTGASLYFTVVAAQRGNPIEQWRAAKAAASEAIMRAGGTIT
HHHAVGADHRPWMRDEVGDLGVEILRAVKATLDPAGILNPGKLIP

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI4501993, Length=570, Percent_Identity=27.719298245614, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI37595756, Length=449, Percent_Identity=27.8396436525612, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI37595754, Length=471, Percent_Identity=26.7515923566879, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI119964728, Length=440, Percent_Identity=25.2272727272727, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI48994907, Length=496, Percent_Identity=28.6290322580645, Blast_Score=174, Evalue=2e-44,
Organism=Escherichia coli, GI1789351, Length=453, Percent_Identity=23.841059602649, Blast_Score=79, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17556096, Length=570, Percent_Identity=30.3508771929825, Blast_Score=275, Evalue=5e-74,
Organism=Caenorhabditis elegans, GI17534361, Length=471, Percent_Identity=23.3545647558386, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320764, Length=452, Percent_Identity=23.6725663716814, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320027, Length=224, Percent_Identity=29.0178571428571, Blast_Score=94, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320023, Length=210, Percent_Identity=33.8095238095238, Blast_Score=94, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24653753, Length=476, Percent_Identity=29.6218487394958, Blast_Score=241, Evalue=9e-64,
Organism=Drosophila melanogaster, GI18921117, Length=514, Percent_Identity=24.3190661478599, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639277, Length=514, Percent_Identity=24.3190661478599, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639275, Length=514, Percent_Identity=24.3190661478599, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 2.5.1.26

Molecular weight: Translated: 54934; Mature: 54934

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWNAWGDPDAAKPLSDGIRALLEQALGVTEGAAPPALEDVTVRPSALPDADRDALGDIV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHH
GAPYCLVDDAGRLLHAGGKSTLDLLRRRDRGEQEAPDAVLLPADEDQIAAILEYCGAQRI
CCCEEEECCCCHHEECCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCCEE
AVVPFGGGTSVVGGLDPIRGDFTAVVSLDLRRLDRLHWLDEVSGEAELGAGVTGPDAERL
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LGERGFSLGHFPQSFCYATIGGFAATRSSGQDSAGYGRFDDMVRGLRAVTPAGVLDIGRA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
PASAAGPDLRQLLVGSEGAFGVITRVRLRVHPVPEVTRYEAWSFPDFATGATALRAVTQT
CCCCCCHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GSGPTVLRLSDEAETGVNLATTEAIGEQTITGGCLAVTVFEGSAAHAESRHAETRALLEE
CCCCEEEEECCCCCCCCCEEHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
HGGRSLGEGPAKAWEHGRFGAPYLRDSLLSAGALCETLETATTWSNVPALKTAVTDALTD
CCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALGRSGTSALVLCHISHVYPTGASLYFTVVAAQRGNPIEQWRAAKAAASEAIMRAGGTIT
HHCCCCCCEEEEEEEHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEE
HHHAVGADHRPWMRDEVGDLGVEILRAVKATLDPAGILNPGKLIP
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKWNAWGDPDAAKPLSDGIRALLEQALGVTEGAAPPALEDVTVRPSALPDADRDALGDIV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCCCCCCCHHHHHHHH
GAPYCLVDDAGRLLHAGGKSTLDLLRRRDRGEQEAPDAVLLPADEDQIAAILEYCGAQRI
CCCEEEECCCCHHEECCCHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHCCCCEE
AVVPFGGGTSVVGGLDPIRGDFTAVVSLDLRRLDRLHWLDEVSGEAELGAGVTGPDAERL
EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
LGERGFSLGHFPQSFCYATIGGFAATRSSGQDSAGYGRFDDMVRGLRAVTPAGVLDIGRA
HHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHCCCC
PASAAGPDLRQLLVGSEGAFGVITRVRLRVHPVPEVTRYEAWSFPDFATGATALRAVTQT
CCCCCCHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GSGPTVLRLSDEAETGVNLATTEAIGEQTITGGCLAVTVFEGSAAHAESRHAETRALLEE
CCCCEEEEECCCCCCCCCEEHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHH
HGGRSLGEGPAKAWEHGRFGAPYLRDSLLSAGALCETLETATTWSNVPALKTAVTDALTD
CCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
ALGRSGTSALVLCHISHVYPTGASLYFTVVAAQRGNPIEQWRAAKAAASEAIMRAGGTIT
HHCCCCCCEEEEEEEHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEE
HHHAVGADHRPWMRDEVGDLGVEILRAVKATLDPAGILNPGKLIP
EEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 1-acyl-glycerone 3-phosphate; long-chain alcohol

Specific reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]