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The map label for this gene is kasB [H]

Identifier: 119869461

GI number: 119869461

Start: 3596123

End: 3597385

Strand: Direct

Name: kasB [H]

Synonym: Mkms_3429

Alternate gene names: 119869461

Gene position: 3596123-3597385 (Clockwise)

Preceding gene: 119869460

Following gene: 119869462

Centisome position: 62.68

GC content: 67.85

Gene sequence:

>1263_bases
ATGGCACGGTTAACCAGGCTTTCGACGGGGAACGGTTTCCCCAACGTGGTCGTCACGGGAGTTGCCATGACGACCGCCCT
GGCTACCGATGCGGAGACCACCTGGCAGCGTCTACTCGACGGGCAGAGCGGTATCCGCACGCTCGAGGATCCGTTCGTCG
AGGAGTACGACCTCCCGGTCCGGATCGGCGGGCATCTGCTGGAGGACTTCGACAGTGAGCTCACGCGTGTCGAGCTGCGC
CGTCTGTCCTACCTGCAGAAGATGTCGACCGTGCTGGGCCGGCGGGTCTGGGCGAACGCCGGTTCCCCGGAGGTCGACCC
GCGTCGGCTGATGGTCTCGATCGGCACGGGCATGGGCTCCACCGAGGAGCTCGTGTTCAGCTACGACGGGATGCGTGCCA
AGGGTCTCAAGGCCGTGTCACCGTTGGCCGTGCAGATGTACATGCCCAACGCGGCCGCCGCCGCGGTGGGTCTGGAGCGC
AAGGCCAGGGCCGGGGTCATCACCCCGGTCTCGGCCTGCGCCTCCGGCTCCGAGGGCATCGCCCAGGCCTGGCGCAACAT
CGTGCTGGGCGAGGCCGACATCGCGATCTGCGGCGGTGTCGAGACCCGGATCGAAGCGGTGCCGATCGCGGGGTTCGCGC
AGATGCGCATCGTGCTGTCGACCACCAACGACGATCCGGCCGGCGCCTGCCGCCCGTTCGACAAGGACCGCAACGGCTTC
GTCTTCGGCGAGGGCGGTGCGCTCCTGGTCATCGAGACCGAGGAACACGCCAAGGCCCGCGGCGCCAACATCCTGGCCCG
CATCATGGGTGCGAGCGTCACCTCGGACGGCTACCACATCGTGGCGCCGGACCCCAACGGTGAACAGGCCGGGTGGGCCA
TGACCCGCGCCATCCAGCTGGCCGGTCTGCAGCCGACCGACATCGACCACGTCAACGCGCACGCCACCGGCACCAGTGTC
GGTGACGTCGCCGAGGGCAAGGCGATCAACAACGCGATGGGCGGTCACAAACCGGCGGTCTACGCACCCAAGGGCGCGCT
CGGCCACTCGGTCGGCGCCGTCGGCGCGGTGGAGTCCATCCTGACGGTGCTGGCGCTCAAGAACGGCGTCATCCCCCCGA
CCCTCAACCTGAAGAACCTGGATCCGGAGATCGACCTCGACGTCGTCGCCGGCTCTCCGCGCCCCGGTAACTACCAGTAC
GCGATCAACAATTCGTTCGGATTCGGTGGGCACAACGTCGCGCTCGCTTTCGGGAAGTACTGA

Upstream 100 bases:

>100_bases
CATCAACAACTCGTTCGGATTCGGCGGCCACAATGTGGCCTTGGCGTTCGGTCGTTACTGAGTAGCGCACGACCAACGGA
AAGACACATACGGAGCAGTA

Downstream 100 bases:

>100_bases
GCACCACAGCTTCTCGACAGTCAGCTGACATCGGAACGGGCACTAGGAGGATTTGAATGACGGTCATGGCCCCCGAGACG
GTCGGCGAAACGCTCGACCC

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: Beta-ketoacyl-ACP synthase 2; KAS 2 [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MARLTRLSTGNGFPNVVVTGVAMTTALATDAETTWQRLLDGQSGIRTLEDPFVEEYDLPVRIGGHLLEDFDSELTRVELR
RLSYLQKMSTVLGRRVWANAGSPEVDPRRLMVSIGTGMGSTEELVFSYDGMRAKGLKAVSPLAVQMYMPNAAAAAVGLER
KARAGVITPVSACASGSEGIAQAWRNIVLGEADIAICGGVETRIEAVPIAGFAQMRIVLSTTNDDPAGACRPFDKDRNGF
VFGEGGALLVIETEEHAKARGANILARIMGASVTSDGYHIVAPDPNGEQAGWAMTRAIQLAGLQPTDIDHVNAHATGTSV
GDVAEGKAINNAMGGHKPAVYAPKGALGHSVGAVGAVESILTVLALKNGVIPPTLNLKNLDPEIDLDVVAGSPRPGNYQY
AINNSFGFGGHNVALAFGKY

Sequences:

>Translated_420_residues
MARLTRLSTGNGFPNVVVTGVAMTTALATDAETTWQRLLDGQSGIRTLEDPFVEEYDLPVRIGGHLLEDFDSELTRVELR
RLSYLQKMSTVLGRRVWANAGSPEVDPRRLMVSIGTGMGSTEELVFSYDGMRAKGLKAVSPLAVQMYMPNAAAAAVGLER
KARAGVITPVSACASGSEGIAQAWRNIVLGEADIAICGGVETRIEAVPIAGFAQMRIVLSTTNDDPAGACRPFDKDRNGF
VFGEGGALLVIETEEHAKARGANILARIMGASVTSDGYHIVAPDPNGEQAGWAMTRAIQLAGLQPTDIDHVNAHATGTSV
GDVAEGKAINNAMGGHKPAVYAPKGALGHSVGAVGAVESILTVLALKNGVIPPTLNLKNLDPEIDLDVVAGSPRPGNYQY
AINNSFGFGGHNVALAFGKY
>Mature_419_residues
ARLTRLSTGNGFPNVVVTGVAMTTALATDAETTWQRLLDGQSGIRTLEDPFVEEYDLPVRIGGHLLEDFDSELTRVELRR
LSYLQKMSTVLGRRVWANAGSPEVDPRRLMVSIGTGMGSTEELVFSYDGMRAKGLKAVSPLAVQMYMPNAAAAAVGLERK
ARAGVITPVSACASGSEGIAQAWRNIVLGEADIAICGGVETRIEAVPIAGFAQMRIVLSTTNDDPAGACRPFDKDRNGFV
FGEGGALLVIETEEHAKARGANILARIMGASVTSDGYHIVAPDPNGEQAGWAMTRAIQLAGLQPTDIDHVNAHATGTSVG
DVAEGKAINNAMGGHKPAVYAPKGALGHSVGAVGAVESILTVLALKNGVIPPTLNLKNLDPEIDLDVVAGSPRPGNYQYA
INNSFGFGGHNVALAFGKY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=36.4508393285372, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=46.5753424657534, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI41872631, Length=254, Percent_Identity=27.5590551181102, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1787337, Length=411, Percent_Identity=37.4695863746959, Blast_Score=228, Evalue=5e-61,
Organism=Escherichia coli, GI1788663, Length=409, Percent_Identity=34.4743276283619, Blast_Score=188, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=33.0097087378641, Blast_Score=202, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI71983535, Length=263, Percent_Identity=39.5437262357414, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17550940, Length=272, Percent_Identity=27.9411764705882, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI212642053, Length=372, Percent_Identity=25, Blast_Score=85, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=449, Percent_Identity=34.9665924276169, Blast_Score=225, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24644341, Length=434, Percent_Identity=36.405529953917, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI19920632, Length=418, Percent_Identity=25.5980861244019, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221330659, Length=418, Percent_Identity=25.5980861244019, Blast_Score=95, Evalue=8e-20,
Organism=Drosophila melanogaster, GI24581345, Length=426, Percent_Identity=24.4131455399061, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 44102; Mature: 43970

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARLTRLSTGNGFPNVVVTGVAMTTALATDAETTWQRLLDGQSGIRTLEDPFVEEYDLPV
CCCEEEECCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCHHCCCCHHHCCCCE
RIGGHLLEDFDSELTRVELRRLSYLQKMSTVLGRRVWANAGSPEVDPRRLMVSIGTGMGS
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
TEELVFSYDGMRAKGLKAVSPLAVQMYMPNAAAAAVGLERKARAGVITPVSACASGSEGI
CCEEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHCCCHHHCCCCCCHHHHHCCCCHHH
AQAWRNIVLGEADIAICGGVETRIEAVPIAGFAQMRIVLSTTNDDPAGACRPFDKDRNGF
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCCCEE
VFGEGGALLVIETEEHAKARGANILARIMGASVTSDGYHIVAPDPNGEQAGWAMTRAIQL
EEECCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHHC
AGLQPTDIDHVNAHATGTSVGDVAEGKAINNAMGGHKPAVYAPKGALGHSVGAVGAVESI
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHH
LTVLALKNGVIPPTLNLKNLDPEIDLDVVAGSPRPGNYQYAINNSFGFGGHNVALAFGKY
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEEEECCC
>Mature Secondary Structure 
ARLTRLSTGNGFPNVVVTGVAMTTALATDAETTWQRLLDGQSGIRTLEDPFVEEYDLPV
CCEEEECCCCCCCCCEEEHHHHHHHHHCCHHHHHHHHHCCCCCCCHHCCCCHHHCCCCE
RIGGHLLEDFDSELTRVELRRLSYLQKMSTVLGRRVWANAGSPEVDPRRLMVSIGTGMGS
EECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCC
TEELVFSYDGMRAKGLKAVSPLAVQMYMPNAAAAAVGLERKARAGVITPVSACASGSEGI
CCEEEEEECCCCCCCCCCCCCEEEEEECCCHHHHHHCCCHHHCCCCCCHHHHHCCCCHHH
AQAWRNIVLGEADIAICGGVETRIEAVPIAGFAQMRIVLSTTNDDPAGACRPFDKDRNGF
HHHHHHHCCCCCCEEEECCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCCCCCCCCCEE
VFGEGGALLVIETEEHAKARGANILARIMGASVTSDGYHIVAPDPNGEQAGWAMTRAIQL
EEECCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHHC
AGLQPTDIDHVNAHATGTSVGDVAEGKAINNAMGGHKPAVYAPKGALGHSVGAVGAVESI
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHH
LTVLALKNGVIPPTLNLKNLDPEIDLDVVAGSPRPGNYQYAINNSFGFGGHNVALAFGKY
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]