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The map label for this gene is dtd [H]

Identifier: 119869415

GI number: 119869415

Start: 3547690

End: 3548154

Strand: Direct

Name: dtd [H]

Synonym: Mkms_3383

Alternate gene names: 119869415

Gene position: 3547690-3548154 (Clockwise)

Preceding gene: 119869414

Following gene: 119869416

Centisome position: 61.84

GC content: 68.39

Gene sequence:

>465_bases
ATGCCACCCGGCCTTTTCGCTTGGATGGAGCCCATGCGCGTTCTGGTCCAGCGGGTGTCCTCGGCAAGGGTCGTCGTCGA
CGGCGAGGTGGTGGGCGCCATCGCACCCGCCCACCAGGGCCTCCTCGCGCTGGTCGGGGTCACCCACACCGACGACGCCG
ACATCGCCCGCAAACTCGCCGAAAAGCTATGGCAGCTGCGCATTCTCGATGGGGAGCGCTCGGCTGCCGACGAGACGGCG
CCCATCCTGGTGGTCAGCCAGTTCACCCTCTACGCCAACACCGTCAAGGGGCGGCGGCCGTCGTGGAACGCCGCGGCGCC
GCGGCCGGTCGCCGAACCGTTGGTGGTGGCGTTCTGCGAGGCGCTGCGGGGGCTGGGAGCGCCGGTGCAAACAGGAGTTT
TCGGGGCGCACATGAATGTGGAACTGGTGAACGACGGTCCGGTAACAGTGCTGCTGGAGCTCTGA

Upstream 100 bases:

>100_bases
TCGGCTCGCCGACGCGACGTTTAGTCGGCTCGCCGACGCGACGTCTAGTCGGCTCGCCGACGCGACGTCTAGGTCGACAG
CGAAAGGCCGGGTGGCGTGC

Downstream 100 bases:

>100_bases
AAATCCGCTGTGTTCGCGCGTAAGGTCACCCCATGGCGACCAATTTCGACGCTCGGCTGGCGAATTACTCGTCACCGTTG
CTGAGCATCTTCCGGATCAT

Product: D-tyrosyl-tRNA(Tyr) deacylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MPPGLFAWMEPMRVLVQRVSSARVVVDGEVVGAIAPAHQGLLALVGVTHTDDADIARKLAEKLWQLRILDGERSAADETA
PILVVSQFTLYANTVKGRRPSWNAAAPRPVAEPLVVAFCEALRGLGAPVQTGVFGAHMNVELVNDGPVTVLLEL

Sequences:

>Translated_154_residues
MPPGLFAWMEPMRVLVQRVSSARVVVDGEVVGAIAPAHQGLLALVGVTHTDDADIARKLAEKLWQLRILDGERSAADETA
PILVVSQFTLYANTVKGRRPSWNAAAPRPVAEPLVVAFCEALRGLGAPVQTGVFGAHMNVELVNDGPVTVLLEL
>Mature_153_residues
PPGLFAWMEPMRVLVQRVSSARVVVDGEVVGAIAPAHQGLLALVGVTHTDDADIARKLAEKLWQLRILDGERSAADETAP
ILVVSQFTLYANTVKGRRPSWNAAAPRPVAEPLVVAFCEALRGLGAPVQTGVFGAHMNVELVNDGPVTVLLEL

Specific function: Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine [H]

COG id: COG1490

COG function: function code J; D-Tyr-tRNAtyr deacylase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DTD family [H]

Homologues:

Organism=Homo sapiens, GI30795227, Length=150, Percent_Identity=37.3333333333333, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1790320, Length=148, Percent_Identity=43.9189189189189, Blast_Score=100, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI115533292, Length=150, Percent_Identity=36, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319982, Length=150, Percent_Identity=38, Blast_Score=96, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281361569, Length=149, Percent_Identity=38.255033557047, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003732 [H]

Pfam domain/function: PF02580 Tyr_Deacylase [H]

EC number: NA

Molecular weight: Translated: 16438; Mature: 16307

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPGLFAWMEPMRVLVQRVSSARVVVDGEVVGAIAPAHQGLLALVGVTHTDDADIARKLA
CCCCHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCHHCCEEEEEECCCCCCHHHHHHHH
EKLWQLRILDGERSAADETAPILVVSQFTLYANTVKGRRPSWNAAAPRPVAEPLVVAFCE
HHHHEEEEECCCCCCCCCCCCEEEEEHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALRGLGAPVQTGVFGAHMNVELVNDGPVTVLLEL
HHHHCCCCCCCCEEECEEEEEEECCCCEEEEEEC
>Mature Secondary Structure 
PPGLFAWMEPMRVLVQRVSSARVVVDGEVVGAIAPAHQGLLALVGVTHTDDADIARKLA
CCCHHHHHHHHHHHHHHHCCCEEEECCCEEEEECCHHCCEEEEEECCCCCCHHHHHHHH
EKLWQLRILDGERSAADETAPILVVSQFTLYANTVKGRRPSWNAAAPRPVAEPLVVAFCE
HHHHEEEEECCCCCCCCCCCCEEEEEHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
ALRGLGAPVQTGVFGAHMNVELVNDGPVTVLLEL
HHHHCCCCCCCCEEECEEEEEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA