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The map label for this gene is cobT [H]

Identifier: 119869399

GI number: 119869399

Start: 3530112

End: 3531164

Strand: Direct

Name: cobT [H]

Synonym: Mkms_3367

Alternate gene names: 119869399

Gene position: 3530112-3531164 (Clockwise)

Preceding gene: 119869398

Following gene: 119869400

Centisome position: 61.53

GC content: 75.59

Gene sequence:

>1053_bases
GTGACGTTCGCCGCCGTGGAGTTCGCCGATGTGGTGCCACCGGACGCGGGCGCGGCGGCCGAGGCGCGGGGGCGTCAGGG
CCGGCTCACCAAACCGGCGGGGGCGCTCGGCCGGCTCGAGGAGCTCTCGGTGTGGGTGTCGGCCTGCCAGGGTGTGTGCC
CGCCCCGGCAGTTCAGCCGGCCGAGGGTGGTGGTGTTCGCCGGTGACCACGGTGTCGCCGGCGCCGGGGTGTCGGCGTAT
CCGGCAGAGGTCACCGCGCAGATGGTCGCCAACATCTCGGCGGGCGGCGCGGCGATCAACGCACTGGCCGAGGTGGCAGG
CGCCGGGGTGCGCGTCGTCGACGTCGCGGTGGACTGCGACGAACCGCTGACGCCGGCGATCGGCGCGGTCAAGGTCCGGC
GCGGCAGCGGCAACATCGCAAACGAGGACGCGCTGAGCGACGAGGAGACCGAGGCGGCGCTGGCGGCGGGCCGCCGGATC
GCCGACGAGGAGGTGGACTCCGGGGCCGACCTGTTGATCGCCGGCGACATGGGCATCGGGAACACAACGGCCGCAACGGC
TTTGATCGCCGTCCTGACGAACTCCGAACCGGTGGTGGTGGTCGGGCGCGGGACCGGCATCGACGACGCCGGCTGGGCGC
GTAAGACCGCCGCGGTCCGCGACGCGATGTACCGGGCGCGGACGGCGGCGGCCGATCCGGCGGCGCTGCTGAGGATCTGC
GGCGGTGCCGATCTGGCCGCGATGGCCGGGTTCTGCGCGCAGGCCGCGGTGCGCCGCACCCCGCTGCTGCTCGACGGCCT
GGTGGTGACGGCGGCCGCGCTGGTGGCCGACCGGCTGGCGCCCGGGGCGCGGCAGTGGTGGCAGGCCGGGCACCGGTCCC
CCGAACCCGGACACACGCTGGCCCTCGACAGCCTGGGGCTGACGCCGATCCTCGACCTGGGCATGCGACTCGGTGAGGGC
ACCGGCGCCGCGGTCGCCCTGCCCGCGGTGCGCGCCGCGGTGGCCGCACTGGCCGGTATGGCGACCTTCGACGAGGCCGG
CGTCTCGTCGTGA

Upstream 100 bases:

>100_bases
TCGCCGACGAACTCGGCGCGCTCAACCAGCGGCTGGCCGCGACGTGCGAGCGGGTGGTGCTGATCGTCGCGGGCCAACCG
ATCACCGTGAAGGAGCCGTC

Downstream 100 bases:

>100_bases
TCGGTTCGCTGGCAGGGGCGTTCGCGTTCGGGACCGTGCTGCCGGTACCTGCGGGCAGCACCGCGACGTTGGGCCGTGGG
GTGATGACCGCGCTGCCCGG

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MTFAAVEFADVVPPDAGAAAEARGRQGRLTKPAGALGRLEELSVWVSACQGVCPPRQFSRPRVVVFAGDHGVAGAGVSAY
PAEVTAQMVANISAGGAAINALAEVAGAGVRVVDVAVDCDEPLTPAIGAVKVRRGSGNIANEDALSDEETEAALAAGRRI
ADEEVDSGADLLIAGDMGIGNTTAATALIAVLTNSEPVVVVGRGTGIDDAGWARKTAAVRDAMYRARTAAADPAALLRIC
GGADLAAMAGFCAQAAVRRTPLLLDGLVVTAAALVADRLAPGARQWWQAGHRSPEPGHTLALDSLGLTPILDLGMRLGEG
TGAAVALPAVRAAVAALAGMATFDEAGVSS

Sequences:

>Translated_350_residues
MTFAAVEFADVVPPDAGAAAEARGRQGRLTKPAGALGRLEELSVWVSACQGVCPPRQFSRPRVVVFAGDHGVAGAGVSAY
PAEVTAQMVANISAGGAAINALAEVAGAGVRVVDVAVDCDEPLTPAIGAVKVRRGSGNIANEDALSDEETEAALAAGRRI
ADEEVDSGADLLIAGDMGIGNTTAATALIAVLTNSEPVVVVGRGTGIDDAGWARKTAAVRDAMYRARTAAADPAALLRIC
GGADLAAMAGFCAQAAVRRTPLLLDGLVVTAAALVADRLAPGARQWWQAGHRSPEPGHTLALDSLGLTPILDLGMRLGEG
TGAAVALPAVRAAVAALAGMATFDEAGVSS
>Mature_349_residues
TFAAVEFADVVPPDAGAAAEARGRQGRLTKPAGALGRLEELSVWVSACQGVCPPRQFSRPRVVVFAGDHGVAGAGVSAYP
AEVTAQMVANISAGGAAINALAEVAGAGVRVVDVAVDCDEPLTPAIGAVKVRRGSGNIANEDALSDEETEAALAAGRRIA
DEEVDSGADLLIAGDMGIGNTTAATALIAVLTNSEPVVVVGRGTGIDDAGWARKTAAVRDAMYRARTAAADPAALLRICG
GADLAAMAGFCAQAAVRRTPLLLDGLVVTAAALVADRLAPGARQWWQAGHRSPEPGHTLALDSLGLTPILDLGMRLGEGT
GAAVALPAVRAAVAALAGMATFDEAGVSS

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=329, Percent_Identity=37.0820668693009, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 35053; Mature: 34922

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAAVEFADVVPPDAGAAAEARGRQGRLTKPAGALGRLEELSVWVSACQGVCPPRQFSR
CCEEEEEHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCC
PRVVVFAGDHGVAGAGVSAYPAEVTAQMVANISAGGAAINALAEVAGAGVRVVDVAVDCD
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEECCC
EPLTPAIGAVKVRRGSGNIANEDALSDEETEAALAAGRRIADEEVDSGADLLIAGDMGIG
CCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCC
NTTAATALIAVLTNSEPVVVVGRGTGIDDAGWARKTAAVRDAMYRARTAAADPAALLRIC
CHHHHHHHHHHEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GGADLAAMAGFCAQAAVRRTPLLLDGLVVTAAALVADRLAPGARQWWQAGHRSPEPGHTL
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEE
ALDSLGLTPILDLGMRLGEGTGAAVALPAVRAAVAALAGMATFDEAGVSS
EECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TFAAVEFADVVPPDAGAAAEARGRQGRLTKPAGALGRLEELSVWVSACQGVCPPRQFSR
CEEEEEHHHCCCCCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCC
PRVVVFAGDHGVAGAGVSAYPAEVTAQMVANISAGGAAINALAEVAGAGVRVVDVAVDCD
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEEEECCC
EPLTPAIGAVKVRRGSGNIANEDALSDEETEAALAAGRRIADEEVDSGADLLIAGDMGIG
CCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCCCCCCEEEECCCCCC
NTTAATALIAVLTNSEPVVVVGRGTGIDDAGWARKTAAVRDAMYRARTAAADPAALLRIC
CHHHHHHHHHHEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GGADLAAMAGFCAQAAVRRTPLLLDGLVVTAAALVADRLAPGARQWWQAGHRSPEPGHTL
CCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEE
ALDSLGLTPILDLGMRLGEGTGAAVALPAVRAAVAALAGMATFDEAGVSS
EECCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA