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The map label for this gene is ampH [C]

Identifier: 119869337

GI number: 119869337

Start: 3467071

End: 3468282

Strand: Direct

Name: ampH [C]

Synonym: Mkms_3305

Alternate gene names: 119869337

Gene position: 3467071-3468282 (Clockwise)

Preceding gene: 119869335

Following gene: 119869338

Centisome position: 60.43

GC content: 69.22

Gene sequence:

>1212_bases
ATGCCTGACCCCCGCCGCATCGTCGGCACACTCGCGGTGCTGCTGCTGGTGACCGCGTGCACGACGGCCGATCCCCCCGA
CCCTGGCCCCGATCCGCGGGCCGACGCGGTGATGCGGATAGTGAACGACACCATGGCCGACGCCCACCTGAAGGCGGCGA
TCGTGCGGGTCACCGAGGACGGTGACGAGATCGTCACCCGCGCCGTCGGCGAATCGATGACCGGCGTGCCCGCCACCGCC
GACATGCACTTCCGCAACGGCGCGGTCGCGATCTCCTACGTCGCGACGCTGCTGCTGCTGCTCGCCGAGGACGGCACCGT
GAGCCTCGACGACCGGCTTTCGCGCTGGCTGCCCGACGTACCGCACGCCGACCGCGTGACACTGGGTCAGCTGGCGCAGA
TGACGTCGGGCTACCACGATTACGTGCTCGGCAACGACGCGTTCGCCGACGCGGCATACGCCGACCCGTTCCGGGCCTAC
ACGACCGACGACCTGCTCGACTTCGCGGTGCACAAGCCGCTGCAGTACGAACCGGGCACCAACTGGAGCTACGCCCACAC
CAACTACGTCCTACTCGGGCTGGCGCTGGAGAAGGCCACCGGCCGCTCCATGACCGACCTGCTCGACGAGAAGGTCCTCC
GACCGCTCGGGCTGACCGGTACCCGCGCCTCGCTGACCGCCGAGATCCCCGAACCGGCGCTGCACGCGTACACCTCCGAA
CGCCGGCAGGCGCTCCGAATACCGGACGGCACAAGCTTTTACGAGGAGTCGACGTACTGGAATCCGTCGTGGACCATCAC
GCACGGCGCCATCCAGACCGCCACCATCGCCGATCTGGAGGCCACCGCCGTCGGCATCGGATCCGGCAAGCTGCTCTCCC
CGGACTCCTACCGCCGCATGGTGTCGACCGACCTGCGGGGCCGCACCCGGGCCCAGCCCGGATGCCCCACCTGCATGCCG
ATGACCGACCGCTACACCTACGGGATCGGCATCGTGATCTCCGGGGACTGGTTGCTGCAGAACCCGATGTTCTCCGGGTA
CGGGGGTCTCGAGGCGTATCTGCCCGCACGCAAGCTCGCGATCGCCGTCGCCGTCACCTTCGCCCCCGAGGCGTTCGACG
CCCAGGGGAACTACACCAACGCCGCACAGACGCTGTTCTCCCGGATCGCCGCCGAACTCGCTCCGGACGACGCGCCACCG
GTACCGCGGTGA

Upstream 100 bases:

>100_bases
ATTGCCCGCACACCACGCGGGCAGCGTCGTATCCGGGTTGCCGCGCTCGTCCGCGGTCAGGAACCAGTCGGACACGTCCG
CCATCTCGCTAGTATCGACC

Downstream 100 bases:

>100_bases
TAATGACCGGGTGACATCCCGAGTCCTGTTCCTGTACAACGATCCCGTCGCCACCGAGGCACTGCTGGGTGAGGCGTTCG
TCGACGCCGGTTACGACGTC

Product: beta-lactamase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MPDPRRIVGTLAVLLLVTACTTADPPDPGPDPRADAVMRIVNDTMADAHLKAAIVRVTEDGDEIVTRAVGESMTGVPATA
DMHFRNGAVAISYVATLLLLLAEDGTVSLDDRLSRWLPDVPHADRVTLGQLAQMTSGYHDYVLGNDAFADAAYADPFRAY
TTDDLLDFAVHKPLQYEPGTNWSYAHTNYVLLGLALEKATGRSMTDLLDEKVLRPLGLTGTRASLTAEIPEPALHAYTSE
RRQALRIPDGTSFYEESTYWNPSWTITHGAIQTATIADLEATAVGIGSGKLLSPDSYRRMVSTDLRGRTRAQPGCPTCMP
MTDRYTYGIGIVISGDWLLQNPMFSGYGGLEAYLPARKLAIAVAVTFAPEAFDAQGNYTNAAQTLFSRIAAELAPDDAPP
VPR

Sequences:

>Translated_403_residues
MPDPRRIVGTLAVLLLVTACTTADPPDPGPDPRADAVMRIVNDTMADAHLKAAIVRVTEDGDEIVTRAVGESMTGVPATA
DMHFRNGAVAISYVATLLLLLAEDGTVSLDDRLSRWLPDVPHADRVTLGQLAQMTSGYHDYVLGNDAFADAAYADPFRAY
TTDDLLDFAVHKPLQYEPGTNWSYAHTNYVLLGLALEKATGRSMTDLLDEKVLRPLGLTGTRASLTAEIPEPALHAYTSE
RRQALRIPDGTSFYEESTYWNPSWTITHGAIQTATIADLEATAVGIGSGKLLSPDSYRRMVSTDLRGRTRAQPGCPTCMP
MTDRYTYGIGIVISGDWLLQNPMFSGYGGLEAYLPARKLAIAVAVTFAPEAFDAQGNYTNAAQTLFSRIAAELAPDDAPP
VPR
>Mature_402_residues
PDPRRIVGTLAVLLLVTACTTADPPDPGPDPRADAVMRIVNDTMADAHLKAAIVRVTEDGDEIVTRAVGESMTGVPATAD
MHFRNGAVAISYVATLLLLLAEDGTVSLDDRLSRWLPDVPHADRVTLGQLAQMTSGYHDYVLGNDAFADAAYADPFRAYT
TDDLLDFAVHKPLQYEPGTNWSYAHTNYVLLGLALEKATGRSMTDLLDEKVLRPLGLTGTRASLTAEIPEPALHAYTSER
RQALRIPDGTSFYEESTYWNPSWTITHGAIQTATIADLEATAVGIGSGKLLSPDSYRRMVSTDLRGRTRAQPGCPTCMPM
TDRYTYGIGIVISGDWLLQNPMFSGYGGLEAYLPARKLAIAVAVTFAPEAFDAQGNYTNAAQTLFSRIAAELAPDDAPPV
PR

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17550934, Length=220, Percent_Identity=24.5454545454545, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 43548; Mature: 43416

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDPRRIVGTLAVLLLVTACTTADPPDPGPDPRADAVMRIVNDTMADAHLKAAIVRVTED
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECC
GDEIVTRAVGESMTGVPATADMHFRNGAVAISYVATLLLLLAEDGTVSLDDRLSRWLPDV
CHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCC
PHADRVTLGQLAQMTSGYHDYVLGNDAFADAAYADPFRAYTTDDLLDFAVHKPLQYEPGT
CCCCCCHHHHHHHHHCCCCCEEECCCHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
NWSYAHTNYVLLGLALEKATGRSMTDLLDEKVLRPLGLTGTRASLTAEIPEPALHAYTSE
CCCCCCCCEEEEEEEEHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHH
RRQALRIPDGTSFYEESTYWNPSWTITHGAIQTATIADLEATAVGIGSGKLLSPDSYRRM
HHHEEECCCCCCCCCCCCEECCCEEEECCCEEEEEEECCCEEEEECCCCCCCCCHHHHHH
VSTDLRGRTRAQPGCPTCMPMTDRYTYGIGIVISGDWLLQNPMFSGYGGLEAYLPARKLA
HHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCEEEECCCCCCCCCHHHHCCHHHEE
IAVAVTFAPEAFDAQGNYTNAAQTLFSRIAAELAPDDAPPVPR
EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PDPRRIVGTLAVLLLVTACTTADPPDPGPDPRADAVMRIVNDTMADAHLKAAIVRVTED
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEEEEEECC
GDEIVTRAVGESMTGVPATADMHFRNGAVAISYVATLLLLLAEDGTVSLDDRLSRWLPDV
CHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCC
PHADRVTLGQLAQMTSGYHDYVLGNDAFADAAYADPFRAYTTDDLLDFAVHKPLQYEPGT
CCCCCCHHHHHHHHHCCCCCEEECCCHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
NWSYAHTNYVLLGLALEKATGRSMTDLLDEKVLRPLGLTGTRASLTAEIPEPALHAYTSE
CCCCCCCCEEEEEEEEHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHH
RRQALRIPDGTSFYEESTYWNPSWTITHGAIQTATIADLEATAVGIGSGKLLSPDSYRRM
HHHEEECCCCCCCCCCCCEECCCEEEECCCEEEEEEECCCEEEEECCCCCCCCCHHHHHH
VSTDLRGRTRAQPGCPTCMPMTDRYTYGIGIVISGDWLLQNPMFSGYGGLEAYLPARKLA
HHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEEECCEEEECCCCCCCCCHHHHCCHHHEE
IAVAVTFAPEAFDAQGNYTNAAQTLFSRIAAELAPDDAPPVPR
EEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]