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The map label for this gene is uppP

Identifier: 119869252

GI number: 119869252

Start: 3378410

End: 3379240

Strand: Reverse

Name: uppP

Synonym: Mkms_3220

Alternate gene names: 119869252

Gene position: 3379240-3378410 (Counterclockwise)

Preceding gene: 119869253

Following gene: 119869251

Centisome position: 58.9

GC content: 68.71

Gene sequence:

>831_bases
ATGTCGTGGTTGCAGGTCATCGTCCTCGCCGTCGTCCAAGGCCTCACCGAATTCCTGCCGGTCTCGTCCTCGGGGCACCT
CGCGATCGTGTCGCGGGTGTTCTTCGACGACGACGCGGGCGCCTCGTTCACGGCGGTCACCCAGCTGGGCACCGAGGTGG
CCGTGCTGGTCTACTTCGCCCGCGACATCGGCCGCATCGCGACCGCCTGGTTCCGTGGCTTGCGCAATCCCGGCCGCCGC
GACGCCGACTACCGGCTGGGCTGGTACGTGATCATCGGCACGATCCCGATCGGGGTCATCGGCCTGCTGCTCAAGGACGA
GATCCGCACCGCCGCCCGCAATCTGTGGGCCATCGCGATCGCGCTGATCGTGTTCTCCGCCGTCATCGCCGCCGCCGAGT
ACTTCGGTCGACAGGTCCGCCACGTCGAACAACTGACCTGGCGCGACGGCGTCATCGTCGGCGTCGCGCAGTGTCTCGCG
CTGCTGCCCGGGGTGTCGCGGTCGGGGGCCACCATCAGCGCCGGGCTGTTCCTCGGCCTGGACCGAGAACTGGCCGCGCG
CTTCGGGTTTCTGCTCGCCATCCCCGCGGTGTTCGCCTCCGGGCTGTTCTCGCTGCCGGACGCCTTCGCCCCGGTGGGTG
AGGGGATGAGCGCCACCGGACCGCAGCTCCTGGTCGCCACGGTGATCGCGTTCGTCGTCGGGTTCGCCGCAGTCGCCTGG
TTCCTGCGATTCCTCGTCCGCCACGGTATGTACTGGTTCGTGGGCTACCGGGTGGTGTTGGGTGTGGTGGTGCTGATCCT
GTTGTCGACCGGGGTGGTGGCCGCGATATGA

Upstream 100 bases:

>100_bases
CGCGGTTCGCGACGCGGTCCGGACCGCCCAGCCGGTGGCGCGACCCGGTCGCTGACACCCCGGCCACGGTACGGTCGTCG
TCGTGATCGACGCACCGGAC

Downstream 100 bases:

>100_bases
CCGTGATCCTGCTGCGGCACGGCCGCTCGACCTCCAACACCGCGCACACCCTCGCCGGCCGCAGCGAAGGTGTGGACCTC
GACGAACGCGGTGCCGAACA

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MSWLQVIVLAVVQGLTEFLPVSSSGHLAIVSRVFFDDDAGASFTAVTQLGTEVAVLVYFARDIGRIATAWFRGLRNPGRR
DADYRLGWYVIIGTIPIGVIGLLLKDEIRTAARNLWAIAIALIVFSAVIAAAEYFGRQVRHVEQLTWRDGVIVGVAQCLA
LLPGVSRSGATISAGLFLGLDRELAARFGFLLAIPAVFASGLFSLPDAFAPVGEGMSATGPQLLVATVIAFVVGFAAVAW
FLRFLVRHGMYWFVGYRVVLGVVVLILLSTGVVAAI

Sequences:

>Translated_276_residues
MSWLQVIVLAVVQGLTEFLPVSSSGHLAIVSRVFFDDDAGASFTAVTQLGTEVAVLVYFARDIGRIATAWFRGLRNPGRR
DADYRLGWYVIIGTIPIGVIGLLLKDEIRTAARNLWAIAIALIVFSAVIAAAEYFGRQVRHVEQLTWRDGVIVGVAQCLA
LLPGVSRSGATISAGLFLGLDRELAARFGFLLAIPAVFASGLFSLPDAFAPVGEGMSATGPQLLVATVIAFVVGFAAVAW
FLRFLVRHGMYWFVGYRVVLGVVVLILLSTGVVAAI
>Mature_275_residues
SWLQVIVLAVVQGLTEFLPVSSSGHLAIVSRVFFDDDAGASFTAVTQLGTEVAVLVYFARDIGRIATAWFRGLRNPGRRD
ADYRLGWYVIIGTIPIGVIGLLLKDEIRTAARNLWAIAIALIVFSAVIAAAEYFGRQVRHVEQLTWRDGVIVGVAQCLAL
LPGVSRSGATISAGLFLGLDRELAARFGFLLAIPAVFASGLFSLPDAFAPVGEGMSATGPQLLVATVIAFVVGFAAVAWF
LRFLVRHGMYWFVGYRVVLGVVVLILLSTGVVAAI

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=270, Percent_Identity=36.2962962962963, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_MYCSJ (A3Q1C2)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001071440.1
- STRING:   A3Q1C2
- EnsemblBacteria:   EBMYCT00000050093
- GeneID:   4878883
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_3170
- eggNOG:   COG1968
- GeneTree:   EBGT00050000016010
- HOGENOM:   HBG391969
- OMA:   HSMYWFV
- PhylomeDB:   A3Q1C2
- ProtClustDB:   PRK00281
- BioCyc:   MSP164757:MJLS_3170-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29567; Mature: 29436

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xacd3f94)-; HASH(0x153acdf4)-; HASH(0x15017344)-; HASH(0x150c3b7c)-; HASH(0x161df350)-; HASH(0x15c80cf8)-; HASH(0x15e0c554)-; HASH(0x166d5678)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SWLQVIVLAVVQGLTEFLPVSSSGHLAIVSRVFFDDDAGASFTAVTQLGTEVAVLVYFA
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
RDIGRIATAWFRGLRNPGRRDADYRLGWYVIIGTIPIGVIGLLLKDEIRTAARNLWAIAI
HHHHHHHHHHHHHCCCCCCCCCCCEEEHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIVFSAVIAAAEYFGRQVRHVEQLTWRDGVIVGVAQCLALLPGVSRSGATISAGLFLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHCC
DRELAARFGFLLAIPAVFASGLFSLPDAFAPVGEGMSATGPQLLVATVIAFVVGFAAVAW
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLRFLVRHGMYWFVGYRVVLGVVVLILLSTGVVAAI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA