| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
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The map label for this gene is metH [H]
Identifier: 119869243
GI number: 119869243
Start: 3366777
End: 3370571
Strand: Reverse
Name: metH [H]
Synonym: Mkms_3211
Alternate gene names: 119869243
Gene position: 3370571-3366777 (Counterclockwise)
Preceding gene: 119869245
Following gene: 119869242
Centisome position: 58.75
GC content: 66.96
Gene sequence:
>3795_bases GTGAACTCCCCTGAGCCGAAAATTCCTGAGCCGAAAATTCCCGGGCCGAAAAATCCTGGGCCCGAGAACTTCGAGCCGAA CATCCGCCCCGACTGCACCGACGAGCTGACCACCGCTCTGAACAGCCGGATCATGGTGATCGACGGCGCGATGGGCACGG CGATCCAGCGGGACCGACCGGACGAGGCCGGCTACCGCGGCGAGCGATTCACGGAGTGGCCCACCGCTCTGCAGGGCAAC AACGACCTGCTCAACCTGACACAGCCGCAGATCATCGAGGCGATCCACCGCGAATACCTCGAGGCGGGCGCCGACATCCT GGAGACCAACACCTTCAACGCGAACGCCATCTCGCTCGCCGACTACGACATGGCGGACCTGAGCTACGAGCTGAACTACG CCGGCGCCGCCCTCGCGCGTAAGGCCGCCGACGAGTACAGCACCGCGGAGAAGCCCCGCTACGTCGCCGGTGCGATCGGA CCCACGACCCGGACCGCATCGATCTCACCGGACGTCAACGACCCCGGCGCCCGCAACGTCTCCTACGACCAGTTGGTCGC CGCCTACCTCGAAGCCGCCAACGGGCTGGTCGACGGTGGGGCCGACCTGATCATCATCGAGACGATCTTCGACTCGCTCA ACGCCAAGGCCGCGGTGTTCGCCGTCGAGACGCTGTTCGAGGACCGCGGACGCCGCTGGCCGGTGATCATCTCCGGCACC ATCACCGACGCCTCCGGACGGACCCTGTCCGGGCAGGTCACCGAAGCGTTCTGGAACGCCATCAGGCACGCGAAGCCGAT CGCGGTCGGCCTCAACTGCGCCCTGGGCGCACCGGAGATGAGGCCCTACATCGCCGAGATGGCGCGCATCGCGGACACGT TCGTCTCCTGCTACCCGAACGCCGGGCTGCCCAACGCCTTCGGCGAGTACGACGAGTCCCCGGAGCGCCAGGCCGGCTAC ATCGCCGACTTCGCCGAGGCCGGGCTGGTGAACCTGGTCGGTGGTTGCTGCGGAACGGCGCCGCCGCACATCGCCGAGAT CGCCAAGGCCGTCGAGGGCAAACCCCCGCGCGAGGTGCCGGAGATCCCGGTGGCCACCCGGCTCTCGGGTCTCGAGCCGC TCAACATCACCGACGACTCGCTGTTCGTGAACATCGGTGAGCGCACCAACATCACCGGCTCCGCCCGGTTCCGCAACCTG ATCAAGGCCGAGGATTACGACACCGCGCTGTCGGTCGCCCTGCAGCAGGTCGAGGTCGGTGCGCAGGTCATCGACATCAA CATGGACGAGGGCATGATCGACGGCGTCGCCGCGATGGATCGGTTCACCAAGCTGATCGCCGCCGAGCCGGACATCAGCC GCGTCCCGGTGATGATCGACTCCTCCAAGTGGGAGGTCATCGAGGCGGGCCTGAAGAACGTGCAGGGCAAGCCGATCGTC AACTCGATCTCCATGAAGGAGGGCGAGGAGAAGTTCATCCGCGAGGCACGGCTGTGCCGCAAGTACGGCGCCGCCGTGGT CGTGATGGCCTTCGACGAGCAGGGTCAGGCCGACAACCTGGAGCGCCGCAAGGAGATCTGCGGGCGCGCCTACCGGATCC TGACCGAAGAGGTCGGCTTCCCGGCCGAGGACATCATCTTCGACCCGAACTGCTTCGCGCTGGCGACCGGTATCGAGGAG CACGCCACCTACGGGATCGACTTCATCGAGGCATGCGCGTGGATCAAGGAGAACCTGCCCGGGGTGCACATCTCCGGCGG CATCTCGAACGTCTCCTTCTCGTTCCGCGGCAACAACCCCGTCCGCGAGGCGATCCACTCGGTCTTCCTGTTCCACGCCA TCAAGGCCGGCCTGGACATGGGCATCGTCAACGCCGGTGCGCTGGTGCCGTACGACTCGATCGACCCCGAGCTGCGTGAC CGCATCGAGGACGTGGTGCTCAACCGTCGCGAGGACGCGGCCGAACGCCTCCTGGAGATCGCCGAACGGTTCAACAAGTC GGAGAAAGCCGACGACCCGGCCGCGGCGGAGTGGCGCAGCCTCCCCGTCCGCGAGCGGATCACGCACGCCCTGGTCAAGG GCATCGACGCCCACGTCGACGCCGACACCGAGGAGCTGCGCGCCGAGATCGCCGCCGCCGGCGGTCGCCCGATCGAGGTG ATCGAGGGCCCGCTGATGGACGGTATGAACGTCGTCGGCGATCTCTTCGGCGCAGGCAAGATGTTCCTGCCCCAGGTCGT GAAGTCGGCCCGCGTGATGAAGAAGGCCGTCGCCTATCTGCTGCCCTACATCGAGGCGGAGAAGGAACAGAACGGCACGA CCGCCAGCAAGGACACCAACGGCACCATCATCATGGCGACGGTGAAGGGCGACGTCCACGACATCGGCAAGAACATCGTC GGAGTCGTCTTGCAGTGCAACAACTTCGAGGTGATCGACCTCGGTGTGATGGTGCCCGCCCAGAAGATCCTCGATGCGGC GAAAGAACACGACGCCGACATCATCGGGCTGTCCGGTTTGATCACCCCGTCCCTGGACGAGATGGTCAACTTCGCCGCCG AAATGGAACGCGAGGGCCTGGAGATCCCGCTGCTGATCGGTGGCGCGACCACCTCACGCGCCCACACCGCCGTGAAGGTC GCCCCGCGCCGCAGCGGCCCGGTGGTCTGGGTCAAGGACGCGTCGCGCTCGGTGCCGGTCGCCGCCGCGCTGCTCGACGA CAAGCAACGGCCGGCGCTGCTGGAGGCCACCGCCAAGGACTACGCATCCCTGCGCGAACGGCACGCCCAGAAGAACGAGC GGCCGATGCTGACGCTGGAGAAGGCCCGCGCGAACCGGACGCCGATCGAGTGGGACGGTTACACGCCGCCGGTGCCCGCA CAGGGCGTCGGGGTGCGGGAATTTCTCGACTACGACCTCGCCGAGCTTCGCGAGTACATCGACTGGCAGCCGTTCTTCAA CGCCTGGGAGATGAAGGGCCGCTTCCCCGACATCCTCAACAACCCGGTCTCGGGCGAGGCCGCCCGCAAGCTGTACGACG ACGCCCAGGAGATGCTCGACACCCTGATCAAGGAGAAGTGGCTGACCGCCAACGGGGTGATCGGCTTCTTCCCGGCCAAC GCCGTCGGCGACGACATCGAGGTCTACACCGACGACACCCGCACCGAGGTGCTGACCACGTTGCACAACCTGCGCCAGCA GGGCGAGCACCGCGACGGCATCCCGAACCGGTCGCTCGGTGACTTCATCGCCCCCAGGGAAACGGGTCTGCGGGACTACG TCGGCGCGTTCGCCGTCACCGCGGGGCTCGGTAGCCAGGACAGGATCGTCGAGTTCAAGGCGGCCAACGACGACTACAGC GCGATCCTGCTGGAGTCGCTCGCCGACCGGCTCGCCGAGGCCTTCGCCGAACGGATGCACCAACGGGTCCGCAAGGAGTT CTGGGGTTATCAGCCCGACGAGCAACTGGACAACGAGGCGCTCATCGGGGAGAAGTACTCAGGCATCCGCCCGGCCCCGG GCTACCCGGCCTGCCCGGAGCACACCGAGAAGGCGACACTCTGGGAGTTGATGGACGTCCAGGAGCGGACCGGCATCGAA CTCACCGAGTCCATGGCGATGTGGCCCGGTGCCGCCGTCAGCGGCTGGTACTTCTCGCACCCGCAGTCGCAGTACTTCGT GGTCGGCCGGCTGGCCCAGGATCAGGTCGCCGACTACGCGAAGCGCAAGGGCTGGACCCTGCCCGAGGCCGAGCGCTGGC TCGCCCCCAACCTCGGCTACAACCCGGAGGACTGA
Upstream 100 bases:
>100_bases GAGAGGCGTTGCAACGGGTTCTGGGGGAGGTCTGCGTCCTTCCCGGTATCCGCCACGCTCGGCAGAGTCAAGGACGCCTT CCGCTACGGAAGGAACGCAC
Downstream 100 bases:
>100_bases ACGTTGATCGTCGCGAATGTGACGTTGTGCGCGAGAATTCGGCAGAAACCCAAACACGAGCTCACGTTCGGCGGGGGACT GCGCGCATGAGAGCGGTGCT
Product: B12-dependent methionine synthase
Products: NA
Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12-dependent; MS [H]
Number of amino acids: Translated: 1264; Mature: 1264
Protein sequence:
>1264_residues MNSPEPKIPEPKIPGPKNPGPENFEPNIRPDCTDELTTALNSRIMVIDGAMGTAIQRDRPDEAGYRGERFTEWPTALQGN NDLLNLTQPQIIEAIHREYLEAGADILETNTFNANAISLADYDMADLSYELNYAGAALARKAADEYSTAEKPRYVAGAIG PTTRTASISPDVNDPGARNVSYDQLVAAYLEAANGLVDGGADLIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVIISGT ITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEMARIADTFVSCYPNAGLPNAFGEYDESPERQAGY IADFAEAGLVNLVGGCCGTAPPHIAEIAKAVEGKPPREVPEIPVATRLSGLEPLNITDDSLFVNIGERTNITGSARFRNL IKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIV NSISMKEGEEKFIREARLCRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGFPAEDIIFDPNCFALATGIEE HATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVREAIHSVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRD RIEDVVLNRREDAAERLLEIAERFNKSEKADDPAAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEV IEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPYIEAEKEQNGTTASKDTNGTIIMATVKGDVHDIGKNIV GVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGLITPSLDEMVNFAAEMEREGLEIPLLIGGATTSRAHTAVKV APRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATAKDYASLRERHAQKNERPMLTLEKARANRTPIEWDGYTPPVPA QGVGVREFLDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPVSGEAARKLYDDAQEMLDTLIKEKWLTANGVIGFFPAN AVGDDIEVYTDDTRTEVLTTLHNLRQQGEHRDGIPNRSLGDFIAPRETGLRDYVGAFAVTAGLGSQDRIVEFKAANDDYS AILLESLADRLAEAFAERMHQRVRKEFWGYQPDEQLDNEALIGEKYSGIRPAPGYPACPEHTEKATLWELMDVQERTGIE LTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLPEAERWLAPNLGYNPED
Sequences:
>Translated_1264_residues MNSPEPKIPEPKIPGPKNPGPENFEPNIRPDCTDELTTALNSRIMVIDGAMGTAIQRDRPDEAGYRGERFTEWPTALQGN NDLLNLTQPQIIEAIHREYLEAGADILETNTFNANAISLADYDMADLSYELNYAGAALARKAADEYSTAEKPRYVAGAIG PTTRTASISPDVNDPGARNVSYDQLVAAYLEAANGLVDGGADLIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVIISGT ITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEMARIADTFVSCYPNAGLPNAFGEYDESPERQAGY IADFAEAGLVNLVGGCCGTAPPHIAEIAKAVEGKPPREVPEIPVATRLSGLEPLNITDDSLFVNIGERTNITGSARFRNL IKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIV NSISMKEGEEKFIREARLCRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGFPAEDIIFDPNCFALATGIEE HATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVREAIHSVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRD RIEDVVLNRREDAAERLLEIAERFNKSEKADDPAAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEV IEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPYIEAEKEQNGTTASKDTNGTIIMATVKGDVHDIGKNIV GVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGLITPSLDEMVNFAAEMEREGLEIPLLIGGATTSRAHTAVKV APRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATAKDYASLRERHAQKNERPMLTLEKARANRTPIEWDGYTPPVPA QGVGVREFLDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPVSGEAARKLYDDAQEMLDTLIKEKWLTANGVIGFFPAN AVGDDIEVYTDDTRTEVLTTLHNLRQQGEHRDGIPNRSLGDFIAPRETGLRDYVGAFAVTAGLGSQDRIVEFKAANDDYS AILLESLADRLAEAFAERMHQRVRKEFWGYQPDEQLDNEALIGEKYSGIRPAPGYPACPEHTEKATLWELMDVQERTGIE LTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLPEAERWLAPNLGYNPED >Mature_1264_residues MNSPEPKIPEPKIPGPKNPGPENFEPNIRPDCTDELTTALNSRIMVIDGAMGTAIQRDRPDEAGYRGERFTEWPTALQGN NDLLNLTQPQIIEAIHREYLEAGADILETNTFNANAISLADYDMADLSYELNYAGAALARKAADEYSTAEKPRYVAGAIG PTTRTASISPDVNDPGARNVSYDQLVAAYLEAANGLVDGGADLIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVIISGT ITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEMARIADTFVSCYPNAGLPNAFGEYDESPERQAGY IADFAEAGLVNLVGGCCGTAPPHIAEIAKAVEGKPPREVPEIPVATRLSGLEPLNITDDSLFVNIGERTNITGSARFRNL IKAEDYDTALSVALQQVEVGAQVIDINMDEGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIV NSISMKEGEEKFIREARLCRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGFPAEDIIFDPNCFALATGIEE HATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNPVREAIHSVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRD RIEDVVLNRREDAAERLLEIAERFNKSEKADDPAAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEV IEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPYIEAEKEQNGTTASKDTNGTIIMATVKGDVHDIGKNIV GVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGLITPSLDEMVNFAAEMEREGLEIPLLIGGATTSRAHTAVKV APRRSGPVVWVKDASRSVPVAAALLDDKQRPALLEATAKDYASLRERHAQKNERPMLTLEKARANRTPIEWDGYTPPVPA QGVGVREFLDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPVSGEAARKLYDDAQEMLDTLIKEKWLTANGVIGFFPAN AVGDDIEVYTDDTRTEVLTTLHNLRQQGEHRDGIPNRSLGDFIAPRETGLRDYVGAFAVTAGLGSQDRIVEFKAANDDYS AILLESLADRLAEAFAERMHQRVRKEFWGYQPDEQLDNEALIGEKYSGIRPAPGYPACPEHTEKATLWELMDVQERTGIE LTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLPEAERWLAPNLGYNPED
Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]
COG id: COG1410
COG function: function code E; Methionine synthase I, cobalamin-binding domain
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 pterin-binding domain [H]
Homologues:
Organism=Homo sapiens, GI169790923, Length=1262, Percent_Identity=53.5657686212361, Blast_Score=1347, Evalue=0.0, Organism=Escherichia coli, GI1790450, Length=1237, Percent_Identity=63.7833468067906, Blast_Score=1595, Evalue=0.0, Organism=Escherichia coli, GI1786456, Length=318, Percent_Identity=24.8427672955975, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17535405, Length=1251, Percent_Identity=54.6762589928058, Blast_Score=1338, Evalue=0.0,
Paralogues:
None
Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006158 - InterPro: IPR011005 - InterPro: IPR003759 - InterPro: IPR011822 - InterPro: IPR000489 - InterPro: IPR003726 - InterPro: IPR004223 [H]
Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]
EC number: =2.1.1.13 [H]
Molecular weight: Translated: 138596; Mature: 138596
Theoretical pI: Translated: 4.46; Mature: 4.46
Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNSPEPKIPEPKIPGPKNPGPENFEPNIRPDCTDELTTALNSRIMVIDGAMGTAIQRDRP CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCHHCCCCC DEAGYRGERFTEWPTALQGNNDLLNLTQPQIIEAIHREYLEAGADILETNTFNANAISLA CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEC DYDMADLSYELNYAGAALARKAADEYSTAEKPRYVAGAIGPTTRTASISPDVNDPGARNV CCCHHHCEEECCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCCCCCCCCCCCC SYDQLVAAYLEAANGLVDGGADLIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVIISGT CHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEE ITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEMARIADTFVSCYPN EECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC AGLPNAFGEYDESPERQAGYIADFAEAGLVNLVGGCCGTAPPHIAEIAKAVEGKPPREVP CCCCCCCCCCCCCCCHHCCHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC EIPVATRLSGLEPLNITDDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVG CCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCC AQVIDINMDEGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIV CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCH NSISMKEGEEKFIREARLCRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGF HHCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCC PAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNP CHHHEEECCCHHEEECCHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCH VREAIHSVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRDRIEDVVLNRREDAAERLLEI HHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH AERFNKSEKADDPAAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEV HHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCCCCHHH IEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPYIEAEKEQNGTTASKDTN HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC GTIIMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGL CEEEEEEECCCHHHHHHHHEEEEEECCCEEEEEEEECCCHHHHHHHHHHCCCCEEEECCC ITPSLDEMVNFAAEMEREGLEIPLLIGGATTSRAHTAVKVAPRRSGPVVWVKDASRSVPV CCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCC AAALLDDKQRPALLEATAKDYASLRERHAQKNERPMLTLEKARANRTPIEWDGYTPPVPA HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCCCCCCCCCCC QGVGVREFLDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPVSGEAARKLYDDAQEMLD CCCCHHHHHCCCHHHHHHHCCCCCCCHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH TLIKEKWLTANGVIGFFPANAVGDDIEVYTDDTRTEVLTTLHNLRQQGEHRDGIPNRSLG HHHHHHCCCCCCEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCC DFIAPRETGLRDYVGAFAVTAGLGSQDRIVEFKAANDDYSAILLESLADRLAEAFAERMH CCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH QRVRKEFWGYQPDEQLDNEALIGEKYSGIRPAPGYPACPEHTEKATLWELMDVQERTGIE HHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCH LTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLPEAERWLAPNLGY HHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC NPED CCCC >Mature Secondary Structure MNSPEPKIPEPKIPGPKNPGPENFEPNIRPDCTDELTTALNSRIMVIDGAMGTAIQRDRP CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCHHCCCCC DEAGYRGERFTEWPTALQGNNDLLNLTQPQIIEAIHREYLEAGADILETNTFNANAISLA CCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHCCCEEECCCCCCCEEEEC DYDMADLSYELNYAGAALARKAADEYSTAEKPRYVAGAIGPTTRTASISPDVNDPGARNV CCCHHHCEEECCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEECCCCCCCCCCCCC SYDQLVAAYLEAANGLVDGGADLIIIETIFDSLNAKAAVFAVETLFEDRGRRWPVIISGT CHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEE ITDASGRTLSGQVTEAFWNAIRHAKPIAVGLNCALGAPEMRPYIAEMARIADTFVSCYPN EECCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCC AGLPNAFGEYDESPERQAGYIADFAEAGLVNLVGGCCGTAPPHIAEIAKAVEGKPPREVP CCCCCCCCCCCCCCCHHCCHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCC EIPVATRLSGLEPLNITDDSLFVNIGERTNITGSARFRNLIKAEDYDTALSVALQQVEVG CCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCC AQVIDINMDEGMIDGVAAMDRFTKLIAAEPDISRVPVMIDSSKWEVIEAGLKNVQGKPIV CEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCH NSISMKEGEEKFIREARLCRKYGAAVVVMAFDEQGQADNLERRKEICGRAYRILTEEVGF HHCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCC PAEDIIFDPNCFALATGIEEHATYGIDFIEACAWIKENLPGVHISGGISNVSFSFRGNNP CHHHEEECCCHHEEECCHHHHHHCCHHHHHHHHHHHHCCCCEEEECCCCEEEEEECCCCH VREAIHSVFLFHAIKAGLDMGIVNAGALVPYDSIDPELRDRIEDVVLNRREDAAERLLEI HHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH AERFNKSEKADDPAAAEWRSLPVRERITHALVKGIDAHVDADTEELRAEIAAAGGRPIEV HHHHCCCCCCCCCCHHHHHCCCHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHCCCCCHHH IEGPLMDGMNVVGDLFGAGKMFLPQVVKSARVMKKAVAYLLPYIEAEKEQNGTTASKDTN HCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC GTIIMATVKGDVHDIGKNIVGVVLQCNNFEVIDLGVMVPAQKILDAAKEHDADIIGLSGL CEEEEEEECCCHHHHHHHHEEEEEECCCEEEEEEEECCCHHHHHHHHHHCCCCEEEECCC ITPSLDEMVNFAAEMEREGLEIPLLIGGATTSRAHTAVKVAPRRSGPVVWVKDASRSVPV CCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCCCCCCC AAALLDDKQRPALLEATAKDYASLRERHAQKNERPMLTLEKARANRTPIEWDGYTPPVPA HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHCCCCCCCCCCCCCCCCC QGVGVREFLDYDLAELREYIDWQPFFNAWEMKGRFPDILNNPVSGEAARKLYDDAQEMLD CCCCHHHHHCCCHHHHHHHCCCCCCCHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH TLIKEKWLTANGVIGFFPANAVGDDIEVYTDDTRTEVLTTLHNLRQQGEHRDGIPNRSLG HHHHHHCCCCCCEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCC DFIAPRETGLRDYVGAFAVTAGLGSQDRIVEFKAANDDYSAILLESLADRLAEAFAERMH CCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH QRVRKEFWGYQPDEQLDNEALIGEKYSGIRPAPGYPACPEHTEKATLWELMDVQERTGIE HHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCH LTESMAMWPGAAVSGWYFSHPQSQYFVVGRLAQDQVADYAKRKGWTLPEAERWLAPNLGY HHHHHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCHHHHCCCCCCC NPED CCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2185137; 2668277; 8369296; 8265357; 9278503; 1593636; 7992050; 8939751 [H]