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The map label for this gene is dinB1 [H]

Identifier: 119869187

GI number: 119869187

Start: 3301953

End: 3303311

Strand: Reverse

Name: dinB1 [H]

Synonym: Mkms_3155

Alternate gene names: 119869187

Gene position: 3303311-3301953 (Counterclockwise)

Preceding gene: 119869189

Following gene: 119869185

Centisome position: 57.58

GC content: 72.04

Gene sequence:

>1359_bases
GTGCGCTGGGTCCTGCACCTGGACATGGACGCGTTCTTCGCGTCGGTCGAGCAGTTGACCCGGCCCACCCTGCGGGGACG
GCCGGTGCTGGTCGGCGGTCTGGGCGGTCGCGGTGTGGTGGCCGGCGCCAGTTACGAGGCCAGGGTGCACGGCGCACGTT
CGGCGATGCCGATGCACCAGGCCCGCCGACTGGTCGGCGCACCGGCGGTGGTGCTGCCACCGCGAGGTGTGGTCTACGGC
CTGGCGAGCCGACGCGTGTTCGACACCGTGCGGACCCTGGTCCCGGTACTCGAACAGTTGTCGTTCGACGAGGCGTTCGG
CGAGCCGCAGGAGCTGGCCGGTGCGTCGGCGGCCGACGTCGAAGAGTTCTGCGAACTGTTGCGCGCGCGGGTGCTGGAGG
AGACCGGGCTGGTGGCCTCGGTGGGGGCGGGGTCGGGCAAGCAGATCGCCAAGATCGCCTCGGGCCTGGCCAAGCCGGAC
GGCATCCGGGTGGTGCGCCGCGCCGACGAACGCCGTCTGCTCGACAGCCTGGCGGTGCGCAAGCTGTGGGGGATCGGACC
GGTCGCCGAGGACAAACTGCACCGCCTCGGCATCGAGACCATCGGTCAGCTCGCGGCGCTCTCGGAGGCCGAGGTAGCCG
ACATCCTCGGCGCCACCGTGGGTCCGGCGCTGCACCGGCTCGCCCGCGGCATCGACGAGCGGCCCGTCGCCGAACGGGCC
GAGGCCAAACAGATCAGCGCCGAGTCCACGTTCCCGGCCGACCTCATCACCCTCGATCAGGTTCGCGAGGCGATCGGGCC
GATCGCCGACCACGCCCACCGGCGACTGGCGAAGGACGGGCGCGGAGCCCGCACGGTCACCGTGAAGCTGAAGAAGTCGG
ATATGAGCACGCTGACCCGGTCGGCCACGCTGCCGTCGGCCACCACCGACGCGGCGACGCTCAGCGCCACCGCCCGCCGG
CTGCTTGTCGACCCCGTCGAGATCGGCCCCATCCGCCTTGTGGGAGTGGGCTTTTCAGGCCTGTCGGAGGTGCGCCAGGA
GTCACTGTTCCCCGACCTGGAACTGGTGGAGGACGAACCGGCCACCCGTCCGGCGGTGCCGATGTCGGTGAGCGAGGCGG
CTGCCGTACCGCCGGCGTGGCGGGTCGGTGACGACGTCGCGCATCCGGAACTGGGGCACGGCTGGATCCAGGGGGCCGGT
CACGGGGTCATGACCATCCGGTTCGAGACGCGCAGCACCGGGCCGGGGCCGGCGAAGACCTTCCCCGACACGGTGCCCGA
CGTCGTCCGGGCCAATCCGGTCGACAGCCTCGACTGGGCGGACTACGTGGACGCGCTCCCGCAGGCCGACCTGCCCTGA

Upstream 100 bases:

>100_bases
GTTTGAGGAACTGACCGAGACGGATCGTGTCGTCACCGATCGGAACCTCGTGCGCCGCCATGACGCTCAGGCTAACGCCC
TAGCATCTGCGGGTGTGGAC

Downstream 100 bases:

>100_bases
CACGTCAGCCCCATTCGGCGAGCACCTCGGCGGCCGGGACGTCCGCGGCGAGTGCGGCCATCAGCAGCACCCGCGCCTGC
GCGGGCCGCAGGGTCGGCAC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPMHQARRLVGAPAVVLPPRGVVYG
LASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAADVEEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAKPD
GIRVVRRADERRLLDSLAVRKLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAERA
EAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTLTRSATLPSATTDAATLSATARR
LLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVEDEPATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQGAG
HGVMTIRFETRSTGPGPAKTFPDTVPDVVRANPVDSLDWADYVDALPQADLP

Sequences:

>Translated_452_residues
MRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPMHQARRLVGAPAVVLPPRGVVYG
LASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAADVEEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAKPD
GIRVVRRADERRLLDSLAVRKLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAERA
EAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTLTRSATLPSATTDAATLSATARR
LLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVEDEPATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQGAG
HGVMTIRFETRSTGPGPAKTFPDTVPDVVRANPVDSLDWADYVDALPQADLP
>Mature_452_residues
MRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPMHQARRLVGAPAVVLPPRGVVYG
LASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAADVEEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAKPD
GIRVVRRADERRLLDSLAVRKLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAERA
EAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTLTRSATLPSATTDAATLSATARR
LLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVEDEPATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQGAG
HGVMTIRFETRSTGPGPAKTFPDTVPDVVRANPVDSLDWADYVDALPQADLP

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=339, Percent_Identity=26.2536873156342, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI7706681, Length=340, Percent_Identity=26.1764705882353, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI5729982, Length=266, Percent_Identity=27.0676691729323, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7705344, Length=252, Percent_Identity=26.5873015873016, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1786425, Length=348, Percent_Identity=32.7586206896552, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787432, Length=299, Percent_Identity=28.0936454849498, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=450, Percent_Identity=24.6666666666667, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI193205702, Length=224, Percent_Identity=32.5892857142857, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193205700, Length=224, Percent_Identity=32.5892857142857, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19923006, Length=440, Percent_Identity=25.6818181818182, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21355641, Length=330, Percent_Identity=24.5454545454545, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644984, Length=330, Percent_Identity=24.5454545454545, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668444, Length=302, Percent_Identity=25.1655629139073, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 48076; Mature: 48076

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPMHQ
CEEEEEECHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCCHHHHCCCHHCCCHHH
ARRLVGAPAVVLPPRGVVYGLASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAADV
HHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCCCCCCCH
EEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAKPDGIRVVRRADERRLLDSLAVR
HHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAERA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
EAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTLTR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHH
SATLPSATTDAATLSATARRLLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVEDEP
HCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEECCCC
ATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQGAGHGVMTIRFETRSTGPGPAKT
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCCCCCC
FPDTVPDVVRANPVDSLDWADYVDALPQADLP
CCCCHHHHHHCCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPMHQ
CEEEEEECHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCCHHHHCCCHHCCCHHH
ARRLVGAPAVVLPPRGVVYGLASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAADV
HHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCCCCCCCH
EEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAKPDGIRVVRRADERRLLDSLAVR
HHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
KLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAERA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
EAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTLTR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHH
SATLPSATTDAATLSATARRLLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVEDEP
HCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEECCCC
ATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQGAGHGVMTIRFETRSTGPGPAKT
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCCCCCC
FPDTVPDVVRANPVDSLDWADYVDALPQADLP
CCCCHHHHHHCCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]