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The map label for this gene is yrhP [H]

Identifier: 119869088

GI number: 119869088

Start: 3198437

End: 3199072

Strand: Direct

Name: yrhP [H]

Synonym: Mkms_3056

Alternate gene names: 119869088

Gene position: 3198437-3199072 (Clockwise)

Preceding gene: 119869087

Following gene: 119869091

Centisome position: 55.75

GC content: 71.54

Gene sequence:

>636_bases
ATGGTCGCCCACCTGCTCGATGTACTACCGGCGTTTCTTCTGGCGGCGGCGATCCTGGCGATACTGCCGGGCCCCGCGAC
GGCGCTGTTCGTCCACCGCGCGATCCGCGACGGCCGCGCCGCCGGTCTGGCCGCCGTCGTCGGCAACGAGATCGGCATCT
TCGGGTGGACGATGGCCGGCGGCGCCGGCCTGTCGGTGCTCCTGCTGGCCAACCGGGCACTGTCGATCGCCCTGCACATC
GTCGGCGCGGCCGTGCTGGTCTGGCTGGGCGTGAGCGCATGGCGGAGCGCCAACCGCCCGGAAATGATCGCCGTTCCGGT
CGAGCCGAGAGCCGGCACGCCGGTCGCGGCGTTCCGCGCGGCGCTGCTGTCCATCGCGGCGAACCCGAAGGCCGCGGCGT
TCGGCATCGTGGTGGTCCCGCAGTTCCTGCCGTCGAGCGGTCCGGTGCTGCTCACCCTCCTGGTGCTCGCGCTGATCCAA
CTGGTGATCGACACCGCGTGGTGTGCGGGCGTGGTGTGGGGTGCTGCACGGGCCCGTGAGCTGTTGAGCCGCGCTCACAT
CCGACGGCGAATCGACCGTGTCATGGGCGCGATCCTGGTGGCGCTGGGACTCGGACTGGCCGCCGAGATGCGCTGA

Upstream 100 bases:

>100_bases
CCAGGGCGGCGTCGCCGGCGCTGCACGGTTTGGGCGAATACCGCGCACCGCGGCCGCTGTGAGTCGGTAACCGACTTGTC
AGGGGCGAGATACTGCTGCC

Downstream 100 bases:

>100_bases
GTCAGTGCGCCGCCGCGTCCCAGCTCCGGCCGTACCCGACACTGACCTCGAGCGGAACGTCGAGGGCGTACGCGCTGCCC
ATCTTGTCGCGGACCAGCTT

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MVAHLLDVLPAFLLAAAILAILPGPATALFVHRAIRDGRAAGLAAVVGNEIGIFGWTMAGGAGLSVLLLANRALSIALHI
VGAAVLVWLGVSAWRSANRPEMIAVPVEPRAGTPVAAFRAALLSIAANPKAAAFGIVVVPQFLPSSGPVLLTLLVLALIQ
LVIDTAWCAGVVWGAARARELLSRAHIRRRIDRVMGAILVALGLGLAAEMR

Sequences:

>Translated_211_residues
MVAHLLDVLPAFLLAAAILAILPGPATALFVHRAIRDGRAAGLAAVVGNEIGIFGWTMAGGAGLSVLLLANRALSIALHI
VGAAVLVWLGVSAWRSANRPEMIAVPVEPRAGTPVAAFRAALLSIAANPKAAAFGIVVVPQFLPSSGPVLLTLLVLALIQ
LVIDTAWCAGVVWGAARARELLSRAHIRRRIDRVMGAILVALGLGLAAEMR
>Mature_211_residues
MVAHLLDVLPAFLLAAAILAILPGPATALFVHRAIRDGRAAGLAAVVGNEIGIFGWTMAGGAGLSVLLLANRALSIALHI
VGAAVLVWLGVSAWRSANRPEMIAVPVEPRAGTPVAAFRAALLSIAANPKAAAFGIVVVPQFLPSSGPVLLTLLVLALIQ
LVIDTAWCAGVVWGAARARELLSRAHIRRRIDRVMGAILVALGLGLAAEMR

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21779; Mature: 21779

Theoretical pI: Translated: 12.16; Mature: 12.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAHLLDVLPAFLLAAAILAILPGPATALFVHRAIRDGRAAGLAAVVGNEIGIFGWTMAG
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCC
GAGLSVLLLANRALSIALHIVGAAVLVWLGVSAWRSANRPEMIAVPVEPRAGTPVAAFRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHH
ALLSIAANPKAAAFGIVVVPQFLPSSGPVLLTLLVLALIQLVIDTAWCAGVVWGAARARE
HHHHHHCCCCHHHHHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSRAHIRRRIDRVMGAILVALGLGLAAEMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVAHLLDVLPAFLLAAAILAILPGPATALFVHRAIRDGRAAGLAAVVGNEIGIFGWTMAG
CHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEECCC
GAGLSVLLLANRALSIALHIVGAAVLVWLGVSAWRSANRPEMIAVPVEPRAGTPVAAFRA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHH
ALLSIAANPKAAAFGIVVVPQFLPSSGPVLLTLLVLALIQLVIDTAWCAGVVWGAARARE
HHHHHHCCCCHHHHHHEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSRAHIRRRIDRVMGAILVALGLGLAAEMR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]