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The map label for this gene is yebQ [C]

Identifier: 119869078

GI number: 119869078

Start: 3187732

End: 3189129

Strand: Reverse

Name: yebQ [C]

Synonym: Mkms_3046

Alternate gene names: 119869078

Gene position: 3189129-3187732 (Counterclockwise)

Preceding gene: 119869079

Following gene: 119869076

Centisome position: 55.59

GC content: 71.32

Gene sequence:

>1398_bases
GTGACTGACACCTCGCGCGTCTCGGTGGGCACCTGGCGCGACCTGCTGGGCCCGGCTCACCTCGGTGCGTCGACGGTGCT
GGCGGGCGGTGTCGCGCTGTATGCGACCAACGAGTTCCTCACCATCAGCCTGATGCCGAGCGCCGTCGCCGACATCGGTG
GTCAGCGGTTCTACGCCTGGGTGACGACGGTGTACCTGGTCGCCTCGGTGATCGCCGCGACGACCGTGCACCCGCTCCTG
ATGCGCCTGGGGCCGCGGCAGGCGTACTGGTCGGGTCTGAGCGTGTTCGCGGCCGGCAGCCTGGGCTGTGCACTCGCCCC
GACGATGGAGTGGCTCCTCGTCGGCCGAACGGTGCAGGGTGGGGCCGGTGGCCTGCTCGCCGGTCTCGGTTACGCCGTGA
TCAACACCGCGCTGCCGAGCCGGTTGTGGACGCGCGCATCGGCGTTGGTGTCGGCCATGTGGGGAGTCGGGACACTCGTC
GGCCCCGCCGCGGGTGGTCTGTTCGCCCAGTTCGGCAGTTGGCGTTGGGCGTTCGGCGTGTTGGTCGGGCTCACCGTCGC
GATGGGGGTGCTGGTGCCGTTCGCGCTTCCGGACCGGGTCGATGGCACCGACGCCGAGCGGCCCCGCCTGCGGATCCCGC
TGTGGTCGCTGCTGTTGCTGGGTGCGGCGGCGTTGGTGGTCAGCATGGCCGGAATCCCACACGATGTGCGGGCCACGGCG
GGACTGCTCCTCGCCGGCGTCGCCATCGTGATGGTGTTCGTGGTCGTGGACCGTCGCGCCACCGTTGCGGTGTTGCCGCC
CAGCGCTTTCGGCCGTGGCCCCCTGAAGTGGATCTACGCGACGCTGGGCCTGCTGATGGCCGCGACGATGGTCGACATGT
ACGTGCCGTTGTTCGGGCAGCGTCTCGCCGGTATGACGCCTGTCGTCGCCGGGTTCTTCGGCGCGGTGCTCTCGGTCGGG
TGGACGGGCGGGGAGATCACCAGCGCCTCGCTGAGCCGCGCGCGGGTGATCGTGCGTACCGTCGCGTGCGCGCCGCTCGT
CATGGCCGCCGGTCTGACGCTCGGCATGTTCGCGCTGCGCGACGAGATGTCGCCGGGCTGGGCTGCGCTGTGGGCGGTCG
GGCTGCTCGTCACCGGTACCGGCATCGGGATCGCCTGGCCCCACCTGTCCGCATGGGCGATGAGTCGCGTCGACGATCCG
GCCGAGGGGCCCGCGGCCGCCGCGGCGATCAACACGGTCCAACTCATCTGCGGAGCCTTCGGCGCCGGCCTGGCGGGTGT
CGTCGTCAACCTCACCGACGCCGGCAACGCAACCGCGGCGCGTTGGCTGTTCGCGGCGTTCGCGGGATTCGTCGCCGTCG
GCGTCCTCGCGTCCACGCGAAGCTGCCGAACCCGTTGA

Upstream 100 bases:

>100_bases
AGATTCAGGACCTCAAGAAGGAACTGCGCGGTATGGACGCCGCGGGCCTGAAGTGACACGTGGTTGACCTCAACCGCTGT
TGAGCTCATAGCGTGGCGGT

Downstream 100 bases:

>100_bases
GCCACAGGTCGTCACGGCGGTCGGAATCACGCTGAGCGAAAAGGTGGGCGCAATGACGGTCGTGGGGCATCGTCAGTGGC
GACGCGGGTGTGGCTGAGTG

Product: major facilitator superfamily transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTDTSRVSVGTWRDLLGPAHLGASTVLAGGVALYATNEFLTISLMPSAVADIGGQRFYAWVTTVYLVASVIAATTVHPLL
MRLGPRQAYWSGLSVFAAGSLGCALAPTMEWLLVGRTVQGGAGGLLAGLGYAVINTALPSRLWTRASALVSAMWGVGTLV
GPAAGGLFAQFGSWRWAFGVLVGLTVAMGVLVPFALPDRVDGTDAERPRLRIPLWSLLLLGAAALVVSMAGIPHDVRATA
GLLLAGVAIVMVFVVVDRRATVAVLPPSAFGRGPLKWIYATLGLLMAATMVDMYVPLFGQRLAGMTPVVAGFFGAVLSVG
WTGGEITSASLSRARVIVRTVACAPLVMAAGLTLGMFALRDEMSPGWAALWAVGLLVTGTGIGIAWPHLSAWAMSRVDDP
AEGPAAAAAINTVQLICGAFGAGLAGVVVNLTDAGNATAARWLFAAFAGFVAVGVLASTRSCRTR

Sequences:

>Translated_465_residues
MTDTSRVSVGTWRDLLGPAHLGASTVLAGGVALYATNEFLTISLMPSAVADIGGQRFYAWVTTVYLVASVIAATTVHPLL
MRLGPRQAYWSGLSVFAAGSLGCALAPTMEWLLVGRTVQGGAGGLLAGLGYAVINTALPSRLWTRASALVSAMWGVGTLV
GPAAGGLFAQFGSWRWAFGVLVGLTVAMGVLVPFALPDRVDGTDAERPRLRIPLWSLLLLGAAALVVSMAGIPHDVRATA
GLLLAGVAIVMVFVVVDRRATVAVLPPSAFGRGPLKWIYATLGLLMAATMVDMYVPLFGQRLAGMTPVVAGFFGAVLSVG
WTGGEITSASLSRARVIVRTVACAPLVMAAGLTLGMFALRDEMSPGWAALWAVGLLVTGTGIGIAWPHLSAWAMSRVDDP
AEGPAAAAAINTVQLICGAFGAGLAGVVVNLTDAGNATAARWLFAAFAGFVAVGVLASTRSCRTR
>Mature_464_residues
TDTSRVSVGTWRDLLGPAHLGASTVLAGGVALYATNEFLTISLMPSAVADIGGQRFYAWVTTVYLVASVIAATTVHPLLM
RLGPRQAYWSGLSVFAAGSLGCALAPTMEWLLVGRTVQGGAGGLLAGLGYAVINTALPSRLWTRASALVSAMWGVGTLVG
PAAGGLFAQFGSWRWAFGVLVGLTVAMGVLVPFALPDRVDGTDAERPRLRIPLWSLLLLGAAALVVSMAGIPHDVRATAG
LLLAGVAIVMVFVVVDRRATVAVLPPSAFGRGPLKWIYATLGLLMAATMVDMYVPLFGQRLAGMTPVVAGFFGAVLSVGW
TGGEITSASLSRARVIVRTVACAPLVMAAGLTLGMFALRDEMSPGWAALWAVGLLVTGTGIGIAWPHLSAWAMSRVDDPA
EGPAAAAAINTVQLICGAFGAGLAGVVVNLTDAGNATAARWLFAAFAGFVAVGVLASTRSCRTR

Specific function: Could be involved in fluoroquinolones efflux [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=265, Percent_Identity=27.1698113207547, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47831; Mature: 47700

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTSRVSVGTWRDLLGPAHLGASTVLAGGVALYATNEFLTISLMPSAVADIGGQRFYAW
CCCCCCEECCHHHHHCCHHHCCHHHHHHCCEEEEEECCEEEEEECHHHHHHCCCCHHHHH
VTTVYLVASVIAATTVHPLLMRLGPRQAYWSGLSVFAAGSLGCALAPTMEWLLVGRTVQG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCCCCCHHHHHHHHHHCCCCCCC
GAGGLLAGLGYAVINTALPSRLWTRASALVSAMWGVGTLVGPAAGGLFAQFGSWRWAFGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHH
LVGLTVAMGVLVPFALPDRVDGTDAERPRLRIPLWSLLLLGAAALVVSMAGIPHDVRATA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHH
GLLLAGVAIVMVFVVVDRRATVAVLPPSAFGRGPLKWIYATLGLLMAATMVDMYVPLFGQ
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAGMTPVVAGFFGAVLSVGWTGGEITSASLSRARVIVRTVACAPLVMAAGLTLGMFALR
HHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEMSPGWAALWAVGLLVTGTGIGIAWPHLSAWAMSRVDDPAEGPAAAAAINTVQLICGAF
HCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
GAGLAGVVVNLTDAGNATAARWLFAAFAGFVAVGVLASTRSCRTR
CCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHCCCC
>Mature Secondary Structure 
TDTSRVSVGTWRDLLGPAHLGASTVLAGGVALYATNEFLTISLMPSAVADIGGQRFYAW
CCCCCEECCHHHHHCCHHHCCHHHHHHCCEEEEEECCEEEEEECHHHHHHCCCCHHHHH
VTTVYLVASVIAATTVHPLLMRLGPRQAYWSGLSVFAAGSLGCALAPTMEWLLVGRTVQG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHCCCCCCHHHHHHHHHHCCCCCCC
GAGGLLAGLGYAVINTALPSRLWTRASALVSAMWGVGTLVGPAAGGLFAQFGSWRWAFGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCHHHHHHH
LVGLTVAMGVLVPFALPDRVDGTDAERPRLRIPLWSLLLLGAAALVVSMAGIPHDVRATA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCHHHHHH
GLLLAGVAIVMVFVVVDRRATVAVLPPSAFGRGPLKWIYATLGLLMAATMVDMYVPLFGQ
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLAGMTPVVAGFFGAVLSVGWTGGEITSASLSRARVIVRTVACAPLVMAAGLTLGMFALR
HHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DEMSPGWAALWAVGLLVTGTGIGIAWPHLSAWAMSRVDDPAEGPAAAAAINTVQLICGAF
HCCCCCHHHHHHHHHHHHCCCCCEECCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
GAGLAGVVVNLTDAGNATAARWLFAAFAGFVAVGVLASTRSCRTR
CCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]