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The map label for this gene is yngI [H]

Identifier: 119868967

GI number: 119868967

Start: 3070556

End: 3072232

Strand: Direct

Name: yngI [H]

Synonym: Mkms_2935

Alternate gene names: 119868967

Gene position: 3070556-3072232 (Clockwise)

Preceding gene: 119868966

Following gene: 119868968

Centisome position: 53.52

GC content: 68.63

Gene sequence:

>1677_bases
ATGGTCATGGCCATGAGCGACGGTGGTGTGAGTTTCGATCTGTCGACCGTGTTCAAGACGGTCGCCGAAGCGGTTCCGGA
CAACACGTTCCTGGTGTGGCGGGACCGCAGGCTCAGCTATGCCGAATCCGACGCCCGGGTGGATGGCGTCGCGCACTATC
TGACATCGGTGGGCCTGGGCTGCCATACCAAACGCGATCGCCTGCAGGGGCACGAATCGGGGCAGGACCACCTGGGGATC
TACCTGCGCAACGGCAACGAGTACCTCGAGGCGATGATCGGCAGCTACCGGGCCCGCGTCGCACCGTTCAACGTGAACTA
CCGCTACGTCGACGAAGAACTCACCTATCTGCTCACCGACGCCGACGCGAAGGCTCTCGTCTACGCCGCGGAGTTCGCGC
CGCAGGTCGCCGCGGTGCGGGACCGACTGCCGAACCTGCGGGTGCTGATCCAGGTCGCCGACGACTCCGGTAACGAACTG
CTGCCCGGCGCAGTCGATTACGAGTCGATCGTCACCACGCCCGCACCTGCCGGTGGAATGCCGACGCCGACCGGCGACGA
CCTCTACATCCTCTACACCGGCGGCACCACCGGAATGCCGAAGGGTGTGCTGTGGCGCCAGCACGACATCTTCCTGTCCT
CGATGGGCGGCCGACCGTTCGGCAGCGACACGTTCCTGTCCTCATATGAGGAGCTCGCCGAACGGGCACGGGCCGGCGCG
GGCGCGATGGGGCTGTTGATGATCCCGCCCTTCATGCACGGCGCCGCGCAGTGGGCCGCCTACAACGCGGTGACGATGGG
CGGCAGGCTGGCCATCCCCGACCATGTCGACCGCCTCCACGCCGACGATGCGCTCCGCGTCGCCGCCCGCGAACGCGTGC
TGAGCATCCCGATGGTCGGCGACGCGGTGGCCCGCCCCCTGCTCGACGAGATCGAGCGCGGCGACTACGACCTGTCGGGG
CTCGTCACGCTGACCAACGGCGGCGCACCGCTGTCGCCGACGGTGCGCGACCGGATCCTGGCAGCATTGCCGCACGTCAT
CGTCATGGACGCGGTGGGGTCCTCGGAGTCCGGCGCCCAGATGAGCACCTACGCCAGCGCCGGCGCCGAGGTCGAGGCCG
CGACGTTCACACCGCAGAGCGACACCGCGGTGGTCTCCGCCGACTTCACGCGGGTTCTGCAACCCGGTGAGGGGCCGGGC
TGGCTGGCACGGCGCGACCTCGTCCCCCTCGGATATCTCGGAGACGCAGCCAAAACCGCCAAGACCTTCCCCACCATCGA
CGGGGTCCGCTGGTCGGTGCCCGGTGATCGCGCGAATGTGTTGGCGGACGGGCGGATCGAGCTACTGGGCCGCGATTCGG
TGACCATCAACTCCGGCGGGGAGAAGATCTTCGCCGAGGAGGTGGAACGCGCGGTCGCGGCGCATCCGGCGGTGTACGAC
GTCGTGGTGGTCGGCCGGCCCTCCGAGCGGTGGGGCAGCGAGGTCGTTGCGGTCGTGCAGCTCGCCGAGGGCGCCTCGGC
GACCGACGAGGAACTCGCCGAGGTGTGTTCCCGGTCGATCGCCCGCTACAAGGTGCCGAAGGTGTTTCTCAGGGCCGAGA
AGGTCGTCCGGTCGCCGGCGGGTAAGGCCGACTACCGCTGGGCGAAAGCCGTTGCCACGGAGAGCGTCAGCAGCTGA

Upstream 100 bases:

>100_bases
CTGCTGTGCGTCGGCGCCAGGGGATGGCAGCCGACGGTGCTGACCGGCAGCGGTCTGCATCCGGCCTGACACTTCGACCA
TACGATGTTCGCGTAGTTGT

Downstream 100 bases:

>100_bases
CGACCGGGGCCGGTGGAAATTCCGCCCGGAGGCTCCCCCGTCACACGCTCGGGATGAAAGGATCATCTCGATGGATGTGC
GCTCACGGAACAACGTCCGG

Product: acyl-CoA synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MVMAMSDGGVSFDLSTVFKTVAEAVPDNTFLVWRDRRLSYAESDARVDGVAHYLTSVGLGCHTKRDRLQGHESGQDHLGI
YLRNGNEYLEAMIGSYRARVAPFNVNYRYVDEELTYLLTDADAKALVYAAEFAPQVAAVRDRLPNLRVLIQVADDSGNEL
LPGAVDYESIVTTPAPAGGMPTPTGDDLYILYTGGTTGMPKGVLWRQHDIFLSSMGGRPFGSDTFLSSYEELAERARAGA
GAMGLLMIPPFMHGAAQWAAYNAVTMGGRLAIPDHVDRLHADDALRVAARERVLSIPMVGDAVARPLLDEIERGDYDLSG
LVTLTNGGAPLSPTVRDRILAALPHVIVMDAVGSSESGAQMSTYASAGAEVEAATFTPQSDTAVVSADFTRVLQPGEGPG
WLARRDLVPLGYLGDAAKTAKTFPTIDGVRWSVPGDRANVLADGRIELLGRDSVTINSGGEKIFAEEVERAVAAHPAVYD
VVVVGRPSERWGSEVVAVVQLAEGASATDEELAEVCSRSIARYKVPKVFLRAEKVVRSPAGKADYRWAKAVATESVSS

Sequences:

>Translated_558_residues
MVMAMSDGGVSFDLSTVFKTVAEAVPDNTFLVWRDRRLSYAESDARVDGVAHYLTSVGLGCHTKRDRLQGHESGQDHLGI
YLRNGNEYLEAMIGSYRARVAPFNVNYRYVDEELTYLLTDADAKALVYAAEFAPQVAAVRDRLPNLRVLIQVADDSGNEL
LPGAVDYESIVTTPAPAGGMPTPTGDDLYILYTGGTTGMPKGVLWRQHDIFLSSMGGRPFGSDTFLSSYEELAERARAGA
GAMGLLMIPPFMHGAAQWAAYNAVTMGGRLAIPDHVDRLHADDALRVAARERVLSIPMVGDAVARPLLDEIERGDYDLSG
LVTLTNGGAPLSPTVRDRILAALPHVIVMDAVGSSESGAQMSTYASAGAEVEAATFTPQSDTAVVSADFTRVLQPGEGPG
WLARRDLVPLGYLGDAAKTAKTFPTIDGVRWSVPGDRANVLADGRIELLGRDSVTINSGGEKIFAEEVERAVAAHPAVYD
VVVVGRPSERWGSEVVAVVQLAEGASATDEELAEVCSRSIARYKVPKVFLRAEKVVRSPAGKADYRWAKAVATESVSS
>Mature_558_residues
MVMAMSDGGVSFDLSTVFKTVAEAVPDNTFLVWRDRRLSYAESDARVDGVAHYLTSVGLGCHTKRDRLQGHESGQDHLGI
YLRNGNEYLEAMIGSYRARVAPFNVNYRYVDEELTYLLTDADAKALVYAAEFAPQVAAVRDRLPNLRVLIQVADDSGNEL
LPGAVDYESIVTTPAPAGGMPTPTGDDLYILYTGGTTGMPKGVLWRQHDIFLSSMGGRPFGSDTFLSSYEELAERARAGA
GAMGLLMIPPFMHGAAQWAAYNAVTMGGRLAIPDHVDRLHADDALRVAARERVLSIPMVGDAVARPLLDEIERGDYDLSG
LVTLTNGGAPLSPTVRDRILAALPHVIVMDAVGSSESGAQMSTYASAGAEVEAATFTPQSDTAVVSADFTRVLQPGEGPG
WLARRDLVPLGYLGDAAKTAKTFPTIDGVRWSVPGDRANVLADGRIELLGRDSVTINSGGEKIFAEEVERAVAAHPAVYD
VVVVGRPSERWGSEVVAVVQLAEGASATDEELAEVCSRSIARYKVPKVFLRAEKVVRSPAGKADYRWAKAVATESVSS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=568, Percent_Identity=25.5281690140845, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI187761345, Length=567, Percent_Identity=25.5731922398589, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI187761343, Length=567, Percent_Identity=25.5731922398589, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI38505220, Length=454, Percent_Identity=25.9911894273128, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI145693145, Length=389, Percent_Identity=27.5064267352185, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788107, Length=497, Percent_Identity=24.9496981891348, Blast_Score=83, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994694, Length=549, Percent_Identity=24.0437158469945, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994703, Length=549, Percent_Identity=24.0437158469945, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71994690, Length=549, Percent_Identity=24.0437158469945, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17560308, Length=562, Percent_Identity=24.3772241992883, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17558820, Length=156, Percent_Identity=32.0512820512821, Blast_Score=66, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319699, Length=546, Percent_Identity=22.5274725274725, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24581924, Length=503, Percent_Identity=24.4532803180915, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21355181, Length=498, Percent_Identity=21.0843373493976, Blast_Score=70, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 59791; Mature: 59791

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMAMSDGGVSFDLSTVFKTVAEAVPDNTFLVWRDRRLSYAESDARVDGVAHYLTSVGLG
CEEEEECCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
CHTKRDRLQGHESGQDHLGIYLRNGNEYLEAMIGSYRARVAPFNVNYRYVDEELTYLLTD
CCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHEEEEECCCEEEECCCEEEEEEC
ADAKALVYAAEFAPQVAAVRDRLPNLRVLIQVADDSGNELLPGAVDYESIVTTPAPAGGM
CCCCEEEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCC
PTPTGDDLYILYTGGTTGMPKGVLWRQHDIFLSSMGGRPFGSDTFLSSYEELAERARAGA
CCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GAMGLLMIPPFMHGAAQWAAYNAVTMGGRLAIPDHVDRLHADDALRVAARERVLSIPMVG
CCEEHEECCCHHHHHHHHHHHHEEEECCEEECCHHHHHHCCCHHHHHHHHHHEEECCCCC
DAVARPLLDEIERGDYDLSGLVTLTNGGAPLSPTVRDRILAALPHVIVMDAVGSSESGAQ
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCC
MSTYASAGAEVEAATFTPQSDTAVVSADFTRVLQPGEGPGWLARRDLVPLGYLGDAAKTA
HHHHHCCCCCEEEEEECCCCCCEEEECCHHHHCCCCCCCCCCHHCCCCCCCCCCCHHHHH
KTFPTIDGVRWSVPGDRANVLADGRIELLGRDSVTINSGGEKIFAEEVERAVAAHPAVYD
HCCCCCCCEEEECCCCCCCEEECCEEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCEEE
VVVVGRPSERWGSEVVAVVQLAEGASATDEELAEVCSRSIARYKVPKVFLRAEKVVRSPA
EEEECCCCHHHHHHHEEEHHECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
GKADYRWAKAVATESVSS
CCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MVMAMSDGGVSFDLSTVFKTVAEAVPDNTFLVWRDRRLSYAESDARVDGVAHYLTSVGLG
CEEEEECCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
CHTKRDRLQGHESGQDHLGIYLRNGNEYLEAMIGSYRARVAPFNVNYRYVDEELTYLLTD
CCCCHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHEEEEECCCEEEECCCEEEEEEC
ADAKALVYAAEFAPQVAAVRDRLPNLRVLIQVADDSGNELLPGAVDYESIVTTPAPAGGM
CCCCEEEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCC
PTPTGDDLYILYTGGTTGMPKGVLWRQHDIFLSSMGGRPFGSDTFLSSYEELAERARAGA
CCCCCCCEEEEEECCCCCCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
GAMGLLMIPPFMHGAAQWAAYNAVTMGGRLAIPDHVDRLHADDALRVAARERVLSIPMVG
CCEEHEECCCHHHHHHHHHHHHEEEECCEEECCHHHHHHCCCHHHHHHHHHHEEECCCCC
DAVARPLLDEIERGDYDLSGLVTLTNGGAPLSPTVRDRILAALPHVIVMDAVGSSESGAQ
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCC
MSTYASAGAEVEAATFTPQSDTAVVSADFTRVLQPGEGPGWLARRDLVPLGYLGDAAKTA
HHHHHCCCCCEEEEEECCCCCCEEEECCHHHHCCCCCCCCCCHHCCCCCCCCCCCHHHHH
KTFPTIDGVRWSVPGDRANVLADGRIELLGRDSVTINSGGEKIFAEEVERAVAAHPAVYD
HCCCCCCCEEEECCCCCCCEEECCEEEEEECCEEEECCCCCHHHHHHHHHHHHCCCCEEE
VVVVGRPSERWGSEVVAVVQLAEGASATDEELAEVCSRSIARYKVPKVFLRAEKVVRSPA
EEEECCCCHHHHHHHEEEHHECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCC
GKADYRWAKAVATESVSS
CCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]