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The map label for this gene is cmaA1 [H]

Identifier: 119868961

GI number: 119868961

Start: 3066999

End: 3067880

Strand: Direct

Name: cmaA1 [H]

Synonym: Mkms_2929

Alternate gene names: 119868961

Gene position: 3066999-3067880 (Clockwise)

Preceding gene: 119868960

Following gene: 119868965

Centisome position: 53.46

GC content: 65.19

Gene sequence:

>882_bases
ATGCCCGACACACCGGACGACCCGGACGAGATGAAGCCGCACTTCGACGACGTGCAGGCCCACTACGACCTCTCCGACGA
GTTCTTCGCGCTTTTCCTCGACGCGACCCGGACCTACAGCTGCGCCTACTTCGAACGCGACGACATGACGCTCGAAGAGG
CCCAGTTCGCGAAGATCGACCTCGCGCTGGGCAAGCTCGGTCTGCAACCCGGTATGACGCTGCTCGACGTCGGCTGCGGC
TGGGGTTCGACGATGATGCGGGCGATCGAACGCCACGACGTCGACGTCATCGGGTTGACGTTGTCGGAGAACCAGCGGGC
GCACGTCCAGAGCCGTTTCGCCGCCGACCAGAGCCCGCGCTCCAAGTCCATCCTGTTGCAGGGTTGGGAGCAGTTCGACC
AGCCGGTCGACCGGATCGTGTCGATCGGGGCCTTCGAACATTTCGGCCACGAACGCTATGACGCGTTCTTCGCGATGGCA
CACCGCGTGCTTCCTGACGACGGGGTGATGCTGCTGCACACCATCACCGGGCTGCACCCCGACGAGATGGCCGAGCGCGG
TATGCCGCTGTCGTTCCAGTTCGCCCGGTTCGTCCGGTTCATCGTCACCGAGATCTTCCCGGGCGGCCGCCTACCGTCGA
TCCCGATGGTCGAGGAGCGCGCCGCCGCGGGCGGTTTCACCGTGTCGCGCGTGCAGTCACTGCAGCCGCACTACGCGAAG
ACGCTCGACATCTGGGCCGCCGCGCTGGAGGCACGCCGCGACGAGGCCATCGCAATCCAGTCCGAAGAGGTCTACGACCG
GTACATGAAGTACCTCACCGGCTGCGCCGACATGTTCCGCGTCGGGTACATCGACGTCAACCAGTTCACGCTCGAGAAGT
AG

Upstream 100 bases:

>100_bases
ATGTTCGTCCCACACCTGTGGGGCAATCTGCGGGGCGTGTCCAGCGGTGACGGGCTCGCACCGCGGCGTCCGGTATTGGC
CCCGGTAATACGATGAGCGG

Downstream 100 bases:

>100_bases
GCCGGCTCAGATACCGGTCCAGGATTCGTCGATCATCTCGGCGACGTTGATGACCTGAGCCTGTTTGCTCTCGGGGCTCT
CGATCTCGCCCGCGACGTGG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CMAS; Cyclopropane-fatty-acyl-phospholipid synthase; CFA synthase; Cyclopropane fatty acid synthase; Mycolic acid methyltransferase; MA-MT; S-adenosylmethionine-dependent methyltransferase; AdoMet-MT; SAM-MT [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MPDTPDDPDEMKPHFDDVQAHYDLSDEFFALFLDATRTYSCAYFERDDMTLEEAQFAKIDLALGKLGLQPGMTLLDVGCG
WGSTMMRAIERHDVDVIGLTLSENQRAHVQSRFAADQSPRSKSILLQGWEQFDQPVDRIVSIGAFEHFGHERYDAFFAMA
HRVLPDDGVMLLHTITGLHPDEMAERGMPLSFQFARFVRFIVTEIFPGGRLPSIPMVEERAAAGGFTVSRVQSLQPHYAK
TLDIWAAALEARRDEAIAIQSEEVYDRYMKYLTGCADMFRVGYIDVNQFTLEK

Sequences:

>Translated_293_residues
MPDTPDDPDEMKPHFDDVQAHYDLSDEFFALFLDATRTYSCAYFERDDMTLEEAQFAKIDLALGKLGLQPGMTLLDVGCG
WGSTMMRAIERHDVDVIGLTLSENQRAHVQSRFAADQSPRSKSILLQGWEQFDQPVDRIVSIGAFEHFGHERYDAFFAMA
HRVLPDDGVMLLHTITGLHPDEMAERGMPLSFQFARFVRFIVTEIFPGGRLPSIPMVEERAAAGGFTVSRVQSLQPHYAK
TLDIWAAALEARRDEAIAIQSEEVYDRYMKYLTGCADMFRVGYIDVNQFTLEK
>Mature_292_residues
PDTPDDPDEMKPHFDDVQAHYDLSDEFFALFLDATRTYSCAYFERDDMTLEEAQFAKIDLALGKLGLQPGMTLLDVGCGW
GSTMMRAIERHDVDVIGLTLSENQRAHVQSRFAADQSPRSKSILLQGWEQFDQPVDRIVSIGAFEHFGHERYDAFFAMAH
RVLPDDGVMLLHTITGLHPDEMAERGMPLSFQFARFVRFIVTEIFPGGRLPSIPMVEERAAAGGFTVSRVQSLQPHYAKT
LDIWAAALEARRDEAIAIQSEEVYDRYMKYLTGCADMFRVGYIDVNQFTLEK

Specific function: Catalyzes the conversion of a double bond to a cyclopropane ring at the distal position of an alpha mycolic acid via the transfers of a methylene group from S-adenosyl-L- methionine. Cyclopropanated mycolic acids are key factors participating in cell enve

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=275, Percent_Identity=33.8181818181818, Blast_Score=147, Evalue=7e-37,
Organism=Caenorhabditis elegans, GI133904226, Length=285, Percent_Identity=30.8771929824561, Blast_Score=130, Evalue=9e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 33275; Mature: 33144

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTPDDPDEMKPHFDDVQAHYDLSDEFFALFLDATRTYSCAYFERDDMTLEEAQFAKID
CCCCCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHH
LALGKLGLQPGMTLLDVGCGWGSTMMRAIERHDVDVIGLTLSENQRAHVQSRFAADQSPR
HHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCC
SKSILLQGWEQFDQPVDRIVSIGAFEHFGHERYDAFFAMAHRVLPDDGVMLLHTITGLHP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCH
DEMAERGMPLSFQFARFVRFIVTEIFPGGRLPSIPMVEERAAAGGFTVSRVQSLQPHYAK
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHCCHHHHH
TLDIWAAALEARRDEAIAIQSEEVYDRYMKYLTGCADMFRVGYIDVNQFTLEK
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCEEECCCEECCC
>Mature Secondary Structure 
PDTPDDPDEMKPHFDDVQAHYDLSDEFFALFLDATRTYSCAYFERDDMTLEEAQFAKID
CCCCCCHHHCCCCHHHHHHHCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHH
LALGKLGLQPGMTLLDVGCGWGSTMMRAIERHDVDVIGLTLSENQRAHVQSRFAADQSPR
HHHHHHCCCCCCEEEEECCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHCCCCCC
SKSILLQGWEQFDQPVDRIVSIGAFEHFGHERYDAFFAMAHRVLPDDGVMLLHTITGLHP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEHHHHHHCCCH
DEMAERGMPLSFQFARFVRFIVTEIFPGGRLPSIPMVEERAAAGGFTVSRVQSLQPHYAK
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHCCHHHHH
TLDIWAAALEARRDEAIAIQSEEVYDRYMKYLTGCADMFRVGYIDVNQFTLEK
HHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCEEECCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7604045 [H]