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The map label for this gene is tesA [H]

Identifier: 119868914

GI number: 119868914

Start: 3020979

End: 3021725

Strand: Direct

Name: tesA [H]

Synonym: Mkms_2882

Alternate gene names: 119868914

Gene position: 3020979-3021725 (Clockwise)

Preceding gene: 119868913

Following gene: 119868915

Centisome position: 52.66

GC content: 65.6

Gene sequence:

>747_bases
ATGAACAGTGCCACTCCGTTGAGCGCGACGGCTCAGGCCGCAGTCGAGACGCTCTTCATCTTTCCGCATGCCGGCGGGTC
CGCCGCCGGGTACAAACCCTTCGCCCGCGCGTTCACGATGGATGCGAAACGGATAGCGGTGCAGTACCCGGGCCGAGCCG
GACGCCACGACGTACCGGATCTCGCGAGCATCTCCGCGCTCGCCGACGACATCTATCCACTCCTGCGGCCGAAGATCACC
GGATCCCGCGTCGCCTTCTTCGGCCACAGCATGGGCGGACTGCTCGCCTTCGACATCGCCCGCCGACTGGAACGAGACGG
GGATTGTCCTGCGGCGCTTTTCGTTTCGGCCTCACCGGCGCCCGGCCACGGGGGCTACGAGCAGTTGCACCAGGGTTCGG
ACGACGAACTGCTCGAGATGGTGGCGAGTATGACCGGCACCGATTCCCGGTTCGTCGGCGGGGAATTCGGCGCCACGGTA
CTGAAGACCCTGCGGAACTACGGAGCGATCACCAGCTACAGCTGTCCACCGGGTACCACGGTGTCGTGCCCGGTGTACGC
CTACGCAGCGGCCGACGACGCCGCGGTGACCTACGAGAGCATGCGCGCATGGTCGGAATTCACCACGGACGACTTCGCGT
TACGCACCGTCGCGGGTGACCACTTCTTCATCACCGAGCACGTCGACGAGATCGTCACCGACATCGAGGCGCGACTCACC
GGATGCACCGTTCGGGAACAGGGGTGA

Upstream 100 bases:

>100_bases
TAACACGTGTGTTTTCGGCGATCATCGACAGCGCCGACATTCCACGACGTGCCGTACCGGTTGGCGTGACGCCGGACCGG
ACAGCGGCAGGGGGAACCAC

Downstream 100 bases:

>100_bases
CGCGATGGTCATGAGCCGTGACGCCGAGAAGGATCTCGGTCTGGTGCTGTCCTACCTGACCGGCCGCAAGCTCACGCTCG
ACGAGGTGCTGGCAGCCGTG

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MNSATPLSATAQAAVETLFIFPHAGGSAAGYKPFARAFTMDAKRIAVQYPGRAGRHDVPDLASISALADDIYPLLRPKIT
GSRVAFFGHSMGGLLAFDIARRLERDGDCPAALFVSASPAPGHGGYEQLHQGSDDELLEMVASMTGTDSRFVGGEFGATV
LKTLRNYGAITSYSCPPGTTVSCPVYAYAAADDAAVTYESMRAWSEFTTDDFALRTVAGDHFFITEHVDEIVTDIEARLT
GCTVREQG

Sequences:

>Translated_248_residues
MNSATPLSATAQAAVETLFIFPHAGGSAAGYKPFARAFTMDAKRIAVQYPGRAGRHDVPDLASISALADDIYPLLRPKIT
GSRVAFFGHSMGGLLAFDIARRLERDGDCPAALFVSASPAPGHGGYEQLHQGSDDELLEMVASMTGTDSRFVGGEFGATV
LKTLRNYGAITSYSCPPGTTVSCPVYAYAAADDAAVTYESMRAWSEFTTDDFALRTVAGDHFFITEHVDEIVTDIEARLT
GCTVREQG
>Mature_248_residues
MNSATPLSATAQAAVETLFIFPHAGGSAAGYKPFARAFTMDAKRIAVQYPGRAGRHDVPDLASISALADDIYPLLRPKIT
GSRVAFFGHSMGGLLAFDIARRLERDGDCPAALFVSASPAPGHGGYEQLHQGSDDELLEMVASMTGTDSRFVGGEFGATV
LKTLRNYGAITSYSCPPGTTVSCPVYAYAAADDAAVTYESMRAWSEFTTDDFALRTVAGDHFFITEHVDEIVTDIEARLT
GCTVREQG

Specific function: Unknown

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=224, Percent_Identity=27.2321428571429, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI8922871, Length=195, Percent_Identity=27.6923076923077, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 26417; Mature: 26417

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSATPLSATAQAAVETLFIFPHAGGSAAGYKPFARAFTMDAKRIAVQYPGRAGRHDVPD
CCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHCCHHEEEEECCCCCCCCCCCC
LASISALADDIYPLLRPKITGSRVAFFGHSMGGLLAFDIARRLERDGDCPAALFVSASPA
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
PGHGGYEQLHQGSDDELLEMVASMTGTDSRFVGGEFGATVLKTLRNYGAITSYSCPPGTT
CCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCE
VSCPVYAYAAADDAAVTYESMRAWSEFTTDDFALRTVAGDHFFITEHVDEIVTDIEARLT
EECCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHH
GCTVREQG
CCEEECCC
>Mature Secondary Structure
MNSATPLSATAQAAVETLFIFPHAGGSAAGYKPFARAFTMDAKRIAVQYPGRAGRHDVPD
CCCCCCCHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHCCHHEEEEECCCCCCCCCCCC
LASISALADDIYPLLRPKITGSRVAFFGHSMGGLLAFDIARRLERDGDCPAALFVSASPA
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
PGHGGYEQLHQGSDDELLEMVASMTGTDSRFVGGEFGATVLKTLRNYGAITSYSCPPGTT
CCCCCHHHHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCCE
VSCPVYAYAAADDAAVTYESMRAWSEFTTDDFALRTVAGDHFFITEHVDEIVTDIEARLT
EECCEEEEECCCCHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHH
GCTVREQG
CCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]