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The map label for this gene is papA5

Identifier: 119868904

GI number: 119868904

Start: 2996175

End: 2997407

Strand: Reverse

Name: papA5

Synonym: Mkms_2872

Alternate gene names: 119868904

Gene position: 2997407-2996175 (Counterclockwise)

Preceding gene: 119868905

Following gene: 119868903

Centisome position: 52.24

GC content: 65.69

Gene sequence:

>1233_bases
ATGGCGTACTCCACGTCGGTGATCCGACGGCTCGCACCCAGCGAGAAGTTCTTCGCCGAAACCCAGACCTTCACCTCGAT
CACCGTGCTGCTCGACGGGACCGTGGACATCGACGCCATGGCGGATGCGTTCGACGCCCTCCTCGAGGCCTATCCGGTGT
ACGCGGGCCACCTCGAACCCGATTCCGACGGCGGGTTCGAGTTGGTGGCCGACGACCTGCTGCACCCCGGACTGTGGGTA
CAGTTCGAGGGAGACCCGGCGCCCACCGATCAACTCGATCAGGGTGTGGCGCTGATCTACCTCCTGGTGAAGCCGGATTC
GACGCCGGTCGAGGTCACCCTGTTCATCCACCACAGCCTCGCCGACGGAACCCACATGGCGGGGCTGCTGTTCGAGCTTT
TCGCGCGCTACACCGAGGTCGTCACCACCGGGAGCGCGGGGCCGGTGAGCCCGAATCCGGCGCCCGAGCCGATCGAGACG
GTTCTCGAACAGCGGGGCATTCGCAAACAGCAACGGTCGGGGTTGGATCGCTTCATCCCCGCGATGTTCGCCTACGAGCT
GCCGCCCAAACGCGTGACCACCAGAAGCGCGGCGGAGCGTCCGGCGGCGGTACCGACGACGCGATGCCGGCTGAGCAAGG
CCGAGACGTCGAGTCTGGTGAAGTACGGGCGGGTCAACCGGCTGTTCGTCAACAACCTGATCTCGGCGGCGATCCTGTTG
GCGGAGTGGCAGGTTCGGCGCACACCGCACATCCCGATCCCGTACGTGTACAACGTCAACCTGCGTGCGCTGGTCGAACC
GCCGGTGAGTGCGACCGGGTGCACGCTGGCGATCGGCGTGGCCACCTACCTCGCGCACATCACACCGCAGACCACCATGG
TCGAACTCGCCAGGGGGATCGCGGACATGTTCCAGGCCGATCTGGCCGACGGCGTTGTCCAGCAGTCACTTCTGCACTTC
AACATGCAGTACGAGGGCGCGATCCCCGGTCTGCCGGACGTGGTGCTGTCGACCAACCTCGGCAACGCCGTGGCCATGAG
CACGCCGCCCGGCCTCGAGGTGGTCGGCGTGCAGTCGCAGTTCTACCGCGCGTCGTCTGCCGTCATCGACGTCTACTCAT
TCGGCGTGGTCGGCGGTGAACTGCTCATCGAGCACCACGTCGACGCCGCCGAGACCACCATCGATCTGATCCGGTCGCTT
CTGCGGTCCGTGGTCTCAGAACATCAACACTGA

Upstream 100 bases:

>100_bases
GGCTACCGGAAAGCCAGCATGCGCGGATGAGCGGGCAGCTTCGCGGACGGCCTCCGCATTGCGGCACCGGTCACCGGGCA
GCCCACCGGGAAGGACTCTG

Downstream 100 bases:

>100_bases
AGGGGATTGTTGAACATGAGCTCAACGAGCTGGCTCGCTCGGCGACGCGCCACCGACCTGGGGCCCGGCGCGGCGGACAC
CGTGCACGTCGAACTGAGCG

Product: acyltransferase PapA5

Products: NA

Alternate protein names: Acyltransferase papA5; Phthiocerol/phthiodiolone O-acyltransferase; Polyketide synthase-associated protein A5

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MAYSTSVIRRLAPSEKFFAETQTFTSITVLLDGTVDIDAMADAFDALLEAYPVYAGHLEPDSDGGFELVADDLLHPGLWV
QFEGDPAPTDQLDQGVALIYLLVKPDSTPVEVTLFIHHSLADGTHMAGLLFELFARYTEVVTTGSAGPVSPNPAPEPIET
VLEQRGIRKQQRSGLDRFIPAMFAYELPPKRVTTRSAAERPAAVPTTRCRLSKAETSSLVKYGRVNRLFVNNLISAAILL
AEWQVRRTPHIPIPYVYNVNLRALVEPPVSATGCTLAIGVATYLAHITPQTTMVELARGIADMFQADLADGVVQQSLLHF
NMQYEGAIPGLPDVVLSTNLGNAVAMSTPPGLEVVGVQSQFYRASSAVIDVYSFGVVGGELLIEHHVDAAETTIDLIRSL
LRSVVSEHQH

Sequences:

>Translated_410_residues
MAYSTSVIRRLAPSEKFFAETQTFTSITVLLDGTVDIDAMADAFDALLEAYPVYAGHLEPDSDGGFELVADDLLHPGLWV
QFEGDPAPTDQLDQGVALIYLLVKPDSTPVEVTLFIHHSLADGTHMAGLLFELFARYTEVVTTGSAGPVSPNPAPEPIET
VLEQRGIRKQQRSGLDRFIPAMFAYELPPKRVTTRSAAERPAAVPTTRCRLSKAETSSLVKYGRVNRLFVNNLISAAILL
AEWQVRRTPHIPIPYVYNVNLRALVEPPVSATGCTLAIGVATYLAHITPQTTMVELARGIADMFQADLADGVVQQSLLHF
NMQYEGAIPGLPDVVLSTNLGNAVAMSTPPGLEVVGVQSQFYRASSAVIDVYSFGVVGGELLIEHHVDAAETTIDLIRSL
LRSVVSEHQH
>Mature_409_residues
AYSTSVIRRLAPSEKFFAETQTFTSITVLLDGTVDIDAMADAFDALLEAYPVYAGHLEPDSDGGFELVADDLLHPGLWVQ
FEGDPAPTDQLDQGVALIYLLVKPDSTPVEVTLFIHHSLADGTHMAGLLFELFARYTEVVTTGSAGPVSPNPAPEPIETV
LEQRGIRKQQRSGLDRFIPAMFAYELPPKRVTTRSAAERPAAVPTTRCRLSKAETSSLVKYGRVNRLFVNNLISAAILLA
EWQVRRTPHIPIPYVYNVNLRALVEPPVSATGCTLAIGVATYLAHITPQTTMVELARGIADMFQADLADGVVQQSLLHFN
MQYEGAIPGLPDVVLSTNLGNAVAMSTPPGLEVVGVQSQFYRASSAVIDVYSFGVVGGELLIEHHVDAAETTIDLIRSLL
RSVVSEHQH

Specific function: Catalyzes diesterification of phthiocerol and phthiodiolone with mycocerosic acids, the final step in the phthiocerol and phthiodiolone dimycocerosate esters (PDIM) synthesis

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyltransferase papA5 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PAPA5_MYCSJ (A3Q0G0)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001071128.1
- ProteinModelPortal:   A3Q0G0
- SMR:   A3Q0G0
- STRING:   A3Q0G0
- EnsemblBacteria:   EBMYCT00000051282
- GeneID:   4878571
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_2857
- eggNOG:   NOG10132
- GeneTree:   EBGT00050000017025
- HOGENOM:   HBG568108
- OMA:   ATYLAEI
- ProtClustDB:   PRK09294
- BioCyc:   MSP164757:MJLS_2857-MONOMER

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 44501; Mature: 44370

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: ACT_SITE 118-118

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYSTSVIRRLAPSEKFFAETQTFTSITVLLDGTVDIDAMADAFDALLEAYPVYAGHLEP
CCCCHHHHHHHCCCHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCC
DSDGGFELVADDLLHPGLWVQFEGDPAPTDQLDQGVALIYLLVKPDSTPVEVTLFIHHSL
CCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHCCEEEEEEEECCCCCCEEEEEEEEECC
ADGTHMAGLLFELFARYTEVVTTGSAGPVSPNPAPEPIETVLEQRGIRKQQRSGLDRFIP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHH
AMFAYELPPKRVTTRSAAERPAAVPTTRCRLSKAETSSLVKYGRVNRLFVNNLISAAILL
HHHHHCCCCCHHCCHHHHCCCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEWQVRRTPHIPIPYVYNVNLRALVEPPVSATGCTLAIGVATYLAHITPQTTMVELARGI
HHHHHCCCCCCCCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
ADMFQADLADGVVQQSLLHFNMQYEGAIPGLPDVVLSTNLGNAVAMSTPPGLEVVGVQSQ
HHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCEEECCCCCEEEECCCCCCEEEECHHH
FYRASSAVIDVYSFGVVGGELLIEHHVDAAETTIDLIRSLLRSVVSEHQH
HHHHHHHHEEHHHHHHCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AYSTSVIRRLAPSEKFFAETQTFTSITVLLDGTVDIDAMADAFDALLEAYPVYAGHLEP
CCCHHHHHHHCCCHHHHHHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCC
DSDGGFELVADDLLHPGLWVQFEGDPAPTDQLDQGVALIYLLVKPDSTPVEVTLFIHHSL
CCCCCHHHHHHHHCCCCEEEEECCCCCCHHHHHCCEEEEEEEECCCCCCEEEEEEEEECC
ADGTHMAGLLFELFARYTEVVTTGSAGPVSPNPAPEPIETVLEQRGIRKQQRSGLDRFIP
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHH
AMFAYELPPKRVTTRSAAERPAAVPTTRCRLSKAETSSLVKYGRVNRLFVNNLISAAILL
HHHHHCCCCCHHCCHHHHCCCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
AEWQVRRTPHIPIPYVYNVNLRALVEPPVSATGCTLAIGVATYLAHITPQTTMVELARGI
HHHHHCCCCCCCCCEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHH
ADMFQADLADGVVQQSLLHFNMQYEGAIPGLPDVVLSTNLGNAVAMSTPPGLEVVGVQSQ
HHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCEEECCCCCEEEECCCCCCEEEECHHH
FYRASSAVIDVYSFGVVGGELLIEHHVDAAETTIDLIRSLLRSVVSEHQH
HHHHHHHHEEHHHHHHCCHHHHEECCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA