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The map label for this gene is speB2 [H]

Identifier: 119868810

GI number: 119868810

Start: 2897875

End: 2898912

Strand: Direct

Name: speB2 [H]

Synonym: Mkms_2778

Alternate gene names: 119868810

Gene position: 2897875-2898912 (Clockwise)

Preceding gene: 119868809

Following gene: 119868812

Centisome position: 50.51

GC content: 70.71

Gene sequence:

>1038_bases
ATGGGCCATGCGCACGACCGCGAGCCGCAACGGGATGTCCCGCCGGGAATGGCCGAACAACTCGACCTGCCCCATTCGGG
GATGGCCACTTTCGGTCATCGGCCGTTCCTGACCGAGACCGCCCAACTGGACTCGTGGCGGCCCGATGTCGCGATCGTCG
GTGCGCCGTTCGACGTGGGGACCACCAACCGCCCGGGCGCGCGGTTCGGGCCGCGCGCCATCCGGGCGACGGCGTACGAA
CCCGGCACGTACCACATGGATCTGGGGCTGGAGATCTTCGACTGGCTGGAGGTGGTCGACTTCGGCGACGCCTACTGTCC
GCACGGGCAGACCGAGGTGTCGCACGCCAACATCCGCGAGCGGGTGGCCGCGGTCGCGTCGCGCGGCATCGTGCCGGTCG
TCCTCGGTGGTGACCACTCGATCACGTGGCCGGCAGCCACCGCGGTCGCCGATGTGCACGGCCACGGCAACGTCGGCATC
GTGCACTTCGACGCCCACGCCGACACCGCCGACACCATCGAGGGCAACCTGGCCAGTCACGGCACGCCGATGCGGCGGCT
CATCGAATCGGGTGCGGTCCCCGGAACCCACTTCGTACAAGTCGGTCTGCGCGGCTACTGGCCGCCGCAGGACACCTTCG
AGTGGATGCTCGAACAGGGCATGACCTGGCACACCATGCAGGAGATCTGGGAGCGCGGCTTCCAGGAGGTGATGCGCGAC
GCGGTGGCCGAGGCGCTCGCCAGGGCCGACAAGCTCTACGTCTCCGTGGACATCGACGTCCTCGATCCCGCCCACGCCCC
CGGCACCGGGACCCCGGAACCGGGCGGCATCACCAGCGCGGACCTACTCCGGATGGTCCGGCGGCTCTGTTACGAGCACG
ATGTGGCGGGTGTCGACGTCGTCGAGGTCGCACCGGCCTACGACCACGCCGAACTGACCGTCAACGCCGCGCACCGGGTG
GTGTTCGAAGCGCTGGCCGGGATGGCGGCCCGCAGGCGCGACGCCGCGGGCGCCCAGCCCGGTCCGCCCGCCCGGTGA

Upstream 100 bases:

>100_bases
TCCGACTGGGCCAAGCGGGCGATCCCGGACTGGCTGCGGAGCGCGCTGACCGCCGGCTGATCGCCGCACGATCCGTCGCA
GTGGGCGGTAGCGTCTGCCC

Downstream 100 bases:

>100_bases
CTCAGCCCTTGGTCAGGGTGAACTGCGCGACGTCGGTGTAGCCCTCGCGGAACAGGTCGGCGCAACCGGTCAGGTACTTC
ATGTACCGGTCGTAGACCTC

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase 2; AUH 2 [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MGHAHDREPQRDVPPGMAEQLDLPHSGMATFGHRPFLTETAQLDSWRPDVAIVGAPFDVGTTNRPGARFGPRAIRATAYE
PGTYHMDLGLEIFDWLEVVDFGDAYCPHGQTEVSHANIRERVAAVASRGIVPVVLGGDHSITWPAATAVADVHGHGNVGI
VHFDAHADTADTIEGNLASHGTPMRRLIESGAVPGTHFVQVGLRGYWPPQDTFEWMLEQGMTWHTMQEIWERGFQEVMRD
AVAEALARADKLYVSVDIDVLDPAHAPGTGTPEPGGITSADLLRMVRRLCYEHDVAGVDVVEVAPAYDHAELTVNAAHRV
VFEALAGMAARRRDAAGAQPGPPAR

Sequences:

>Translated_345_residues
MGHAHDREPQRDVPPGMAEQLDLPHSGMATFGHRPFLTETAQLDSWRPDVAIVGAPFDVGTTNRPGARFGPRAIRATAYE
PGTYHMDLGLEIFDWLEVVDFGDAYCPHGQTEVSHANIRERVAAVASRGIVPVVLGGDHSITWPAATAVADVHGHGNVGI
VHFDAHADTADTIEGNLASHGTPMRRLIESGAVPGTHFVQVGLRGYWPPQDTFEWMLEQGMTWHTMQEIWERGFQEVMRD
AVAEALARADKLYVSVDIDVLDPAHAPGTGTPEPGGITSADLLRMVRRLCYEHDVAGVDVVEVAPAYDHAELTVNAAHRV
VFEALAGMAARRRDAAGAQPGPPAR
>Mature_344_residues
GHAHDREPQRDVPPGMAEQLDLPHSGMATFGHRPFLTETAQLDSWRPDVAIVGAPFDVGTTNRPGARFGPRAIRATAYEP
GTYHMDLGLEIFDWLEVVDFGDAYCPHGQTEVSHANIRERVAAVASRGIVPVVLGGDHSITWPAATAVADVHGHGNVGIV
HFDAHADTADTIEGNLASHGTPMRRLIESGAVPGTHFVQVGLRGYWPPQDTFEWMLEQGMTWHTMQEIWERGFQEVMRDA
VAEALARADKLYVSVDIDVLDPAHAPGTGTPEPGGITSADLLRMVRRLCYEHDVAGVDVVEVAPAYDHAELTVNAAHRVV
FEALAGMAARRRDAAGAQPGPPAR

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=280, Percent_Identity=38.2142857142857, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI10947139, Length=313, Percent_Identity=27.7955271565495, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4502215, Length=323, Percent_Identity=26.625386996904, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1789306, Length=286, Percent_Identity=34.2657342657343, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71996843, Length=270, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6325146, Length=210, Percent_Identity=29.5238095238095, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24638886, Length=315, Percent_Identity=26.3492063492064, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 37363; Mature: 37232

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHAHDREPQRDVPPGMAEQLDLPHSGMATFGHRPFLTETAQLDSWRPDVAIVGAPFDVG
CCCCCCCCCCCCCCCCHHHHCCCCCCCHHHCCCCCCCCCHHHCCCCCCCEEEEECCCCCC
TTNRPGARFGPRAIRATAYEPGTYHMDLGLEIFDWLEVVDFGDAYCPHGQTEVSHANIRE
CCCCCCCCCCCHHEEEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
RVAAVASRGIVPVVLGGDHSITWPAATAVADVHGHGNVGIVHFDAHADTADTIEGNLASH
HHHHHHHCCCEEEEECCCCCCCCCHHHHEEEECCCCCEEEEEEECCCCCHHHHCCCHHCC
GTPMRRLIESGAVPGTHFVQVGLRGYWPPQDTFEWMLEQGMTWHTMQEIWERGFQEVMRD
CCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AVAEALARADKLYVSVDIDVLDPAHAPGTGTPEPGGITSADLLRMVRRLCYEHDVAGVDV
HHHHHHHHHCEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
VEVAPAYDHAELTVNAAHRVVFEALAGMAARRRDAAGAQPGPPAR
EEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
GHAHDREPQRDVPPGMAEQLDLPHSGMATFGHRPFLTETAQLDSWRPDVAIVGAPFDVG
CCCCCCCCCCCCCCCHHHHCCCCCCCHHHCCCCCCCCCHHHCCCCCCCEEEEECCCCCC
TTNRPGARFGPRAIRATAYEPGTYHMDLGLEIFDWLEVVDFGDAYCPHGQTEVSHANIRE
CCCCCCCCCCCHHEEEEEECCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHH
RVAAVASRGIVPVVLGGDHSITWPAATAVADVHGHGNVGIVHFDAHADTADTIEGNLASH
HHHHHHHCCCEEEEECCCCCCCCCHHHHEEEECCCCCEEEEEEECCCCCHHHHCCCHHCC
GTPMRRLIESGAVPGTHFVQVGLRGYWPPQDTFEWMLEQGMTWHTMQEIWERGFQEVMRD
CCHHHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
AVAEALARADKLYVSVDIDVLDPAHAPGTGTPEPGGITSADLLRMVRRLCYEHDVAGVDV
HHHHHHHHHCEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
VEVAPAYDHAELTVNAAHRVVFEALAGMAARRRDAAGAQPGPPAR
EEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]