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The map label for this gene is yghZ [H]

Identifier: 119868740

GI number: 119868740

Start: 2830531

End: 2831601

Strand: Direct

Name: yghZ [H]

Synonym: Mkms_2707

Alternate gene names: 119868740

Gene position: 2830531-2831601 (Clockwise)

Preceding gene: 119868739

Following gene: 119868741

Centisome position: 49.34

GC content: 66.76

Gene sequence:

>1071_bases
ATGTCCGGAGACCTGTTGATCGGTGACGCGCCCTTCTCCCACGACCCCTGGGTGGCCAGGCGGGAACGCTACGATTCGAT
GCCGTACCGGCGGGTGGGTGACTCCGGGCTGCTGCTGCCCGCGATCTCGCTGGGCCTCTGGTACAACTTCGGCGACAACC
GGCCGTTCGACGTGCAACGCGAGGTGCTGCGGTACGCCTTCGACCGCGGCATCACGCATTTCGATCTCGCCAACAACTAC
GGCCCGCCGTACGGTTCGGCCGAGGAGAACTTCGGCCGGATGCTGCGCCGGGACTTCAAGCCGTATCGCAACGAGTTGAT
CGTCTCGACCAAGGCCGGCTGGGACATGTGGCCCGGACCGTACGGGCAGCTCGGCGGCCGGGCCTACCTGCTCGCCAGCC
TCGACGAATCACTCGACCGTCTCGGCCTCGACTACGTCGACATCTTCTACTCGCACCGCATCGATCCGACGACACCGCTC
GAGGAGACCGTCGGCGCACTCGACACCGCGGTGCGAGCCGGTAAGACCCGCTACGTCGGGGTCTCGTCGTATTCGGCGGC
CAAGACCGCCGAAGCGGCCGCGATCGCGAGACGTCTCGGCACTCCGTTGGTGATCCACCAGCCGTCGTACTCACTGCTGA
ACCGGTGGATCGAGGGCGACCTCACCACCGAACTCCGCAACGCCGGCATGGGTGCGATCGCGTTCACCGCACTGGCCCAG
GGTCTGCTGACCGACCGCTACCTGCAGTCCGACCCGAGCGAGATCGACCGTGCCACAGCACGACCCACGTTCAACGACGA
GCACATCACCGACCGGGTGCGCGAGCAGCTGCGGGGTCTGGCCGGCATCGCCGAACGTCGTGGACAGTCGCTGGCCCAAC
TCGCGCTGGCGTGGGTGCTCCGTGACCCGACCGTCGCATCCACACTCGTCGGCGCGTCGAGCGTCGCGCAGCTCGAAGAG
AACCTCGGCGCCCTCGACAACCTCGACTTCACCGCCGACGAGCTCGCCGAAATCGACCGGTACGCAACCGAATCCGGAAT
CGACCTGTGGCGAGAGAGCTCCGATGTCTAG

Upstream 100 bases:

>100_bases
GTCGCGTGGGTCGGTTCCGATCAGGATGATCTGGTCGCCCATCTGCCCACATGGTTCGGCGCTCCGGACTGATCCGGTCC
GCGTCACTACGATTGCCCTC

Downstream 100 bases:

>100_bases
CGGTCTGCCATGGATTCGACCCGTATAGACCGCTGGTTGTGGGCGGTCCGGCTGACCAAGACGCGGCCGGACGCCGCAGC
CGCGTGCCGGGGCGGGCACG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSGDLLIGDAPFSHDPWVARRERYDSMPYRRVGDSGLLLPAISLGLWYNFGDNRPFDVQREVLRYAFDRGITHFDLANNY
GPPYGSAEENFGRMLRRDFKPYRNELIVSTKAGWDMWPGPYGQLGGRAYLLASLDESLDRLGLDYVDIFYSHRIDPTTPL
EETVGALDTAVRAGKTRYVGVSSYSAAKTAEAAAIARRLGTPLVIHQPSYSLLNRWIEGDLTTELRNAGMGAIAFTALAQ
GLLTDRYLQSDPSEIDRATARPTFNDEHITDRVREQLRGLAGIAERRGQSLAQLALAWVLRDPTVASTLVGASSVAQLEE
NLGALDNLDFTADELAEIDRYATESGIDLWRESSDV

Sequences:

>Translated_356_residues
MSGDLLIGDAPFSHDPWVARRERYDSMPYRRVGDSGLLLPAISLGLWYNFGDNRPFDVQREVLRYAFDRGITHFDLANNY
GPPYGSAEENFGRMLRRDFKPYRNELIVSTKAGWDMWPGPYGQLGGRAYLLASLDESLDRLGLDYVDIFYSHRIDPTTPL
EETVGALDTAVRAGKTRYVGVSSYSAAKTAEAAAIARRLGTPLVIHQPSYSLLNRWIEGDLTTELRNAGMGAIAFTALAQ
GLLTDRYLQSDPSEIDRATARPTFNDEHITDRVREQLRGLAGIAERRGQSLAQLALAWVLRDPTVASTLVGASSVAQLEE
NLGALDNLDFTADELAEIDRYATESGIDLWRESSDV
>Mature_355_residues
SGDLLIGDAPFSHDPWVARRERYDSMPYRRVGDSGLLLPAISLGLWYNFGDNRPFDVQREVLRYAFDRGITHFDLANNYG
PPYGSAEENFGRMLRRDFKPYRNELIVSTKAGWDMWPGPYGQLGGRAYLLASLDESLDRLGLDYVDIFYSHRIDPTTPLE
ETVGALDTAVRAGKTRYVGVSSYSAAKTAEAAAIARRLGTPLVIHQPSYSLLNRWIEGDLTTELRNAGMGAIAFTALAQG
LLTDRYLQSDPSEIDRATARPTFNDEHITDRVREQLRGLAGIAERRGQSLAQLALAWVLRDPTVASTLVGASSVAQLEEN
LGALDNLDFTADELAEIDRYATESGIDLWRESSDV

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=323, Percent_Identity=34.3653250773994, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=34.2679127725857, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI27436966, Length=323, Percent_Identity=34.3653250773994, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI27436964, Length=337, Percent_Identity=33.2344213649852, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI27436962, Length=330, Percent_Identity=33.6363636363636, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI27436971, Length=330, Percent_Identity=33.030303030303, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI41152114, Length=210, Percent_Identity=29.5238095238095, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI41327764, Length=211, Percent_Identity=29.8578199052133, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI223718702, Length=211, Percent_Identity=29.8578199052133, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789375, Length=343, Percent_Identity=56.8513119533528, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI87081735, Length=327, Percent_Identity=34.2507645259939, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1789199, Length=340, Percent_Identity=30.8823529411765, Blast_Score=111, Evalue=7e-26,
Organism=Escherichia coli, GI1788070, Length=313, Percent_Identity=28.4345047923323, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788081, Length=303, Percent_Identity=26.7326732673267, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994888, Length=284, Percent_Identity=25.3521126760563, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=26.4094955489614, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=27.2, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6319958, Length=274, Percent_Identity=25.9124087591241, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319951, Length=299, Percent_Identity=27.0903010033445, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323998, Length=313, Percent_Identity=24.9201277955272, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24640980, Length=348, Percent_Identity=27.5862068965517, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45549126, Length=348, Percent_Identity=27.5862068965517, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24646155, Length=343, Percent_Identity=27.9883381924198, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646159, Length=337, Percent_Identity=27.5964391691395, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 39557; Mature: 39425

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGDLLIGDAPFSHDPWVARRERYDSMPYRRVGDSGLLLPAISLGLWYNFGDNRPFDVQR
CCCCEEEECCCCCCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHEEECCCCCCCHHHH
EVLRYAFDRGITHFDLANNYGPPYGSAEENFGRMLRRDFKPYRNELIVSTKAGWDMWPGP
HHHHHHHHCCCEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
YGQLGGRAYLLASLDESLDRLGLDYVDIFYSHRIDPTTPLEETVGALDTAVRAGKTRYVG
CCCCCCCEEEHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
VSSYSAAKTAEAAAIARRLGTPLVIHQPSYSLLNRWIEGDLTTELRNAGMGAIAFTALAQ
CCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHH
GLLTDRYLQSDPSEIDRATARPTFNDEHITDRVREQLRGLAGIAERRGQSLAQLALAWVL
HHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDPTVASTLVGASSVAQLEENLGALDNLDFTADELAEIDRYATESGIDLWRESSDV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SGDLLIGDAPFSHDPWVARRERYDSMPYRRVGDSGLLLPAISLGLWYNFGDNRPFDVQR
CCCEEEECCCCCCCCHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHEEECCCCCCCHHHH
EVLRYAFDRGITHFDLANNYGPPYGSAEENFGRMLRRDFKPYRNELIVSTKAGWDMWPGP
HHHHHHHHCCCEEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCC
YGQLGGRAYLLASLDESLDRLGLDYVDIFYSHRIDPTTPLEETVGALDTAVRAGKTRYVG
CCCCCCCEEEHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
VSSYSAAKTAEAAAIARRLGTPLVIHQPSYSLLNRWIEGDLTTELRNAGMGAIAFTALAQ
CCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHH
GLLTDRYLQSDPSEIDRATARPTFNDEHITDRVREQLRGLAGIAERRGQSLAQLALAWVL
HHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDPTVASTLVGASSVAQLEENLGALDNLDFTADELAEIDRYATESGIDLWRESSDV
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]