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The map label for this gene is dhaK [H]

Identifier: 119868640

GI number: 119868640

Start: 2739637

End: 2741382

Strand: Direct

Name: dhaK [H]

Synonym: Mkms_2605

Alternate gene names: 119868640

Gene position: 2739637-2741382 (Clockwise)

Preceding gene: 119868639

Following gene: 119868641

Centisome position: 47.75

GC content: 71.88

Gene sequence:

>1746_bases
GTGACGAAGCTGTTCAACGATCCGGCCCGGTTCACCGAGGACATGCTCGTCGGATTCCTCGACGCGAATTCGCGTTACGT
GGCCGGGGTTCCGGGTGGGGTGGTGCGTGCGCACGAGACCCGTCCCGGCAAGGTGGCGGTCGTAATCGGCGGTGGGTCCG
GGCACTACCCGGCGTTCTGCGGCACCGTCGGACCGGGCTTCGCCGACGGTGCGGTGGTCGGCAACATCTTCACCTCGCCG
TCCACGGAGGAGGCCGCATCGGTCGCCCGTGCCGCGCACGGCGATGCCGGTGTCCTGCTCATCACGGGCAACTACGCCGG
TGACGTCATGAACTTCGGGTTGGCCGTCACCGCGTTACGCGGCGAGGGTGTCGACGCCCACTACTTCGCCGTCACCGACG
ACATCGCCAGCGCGCCGAAGGGTGAGGAGGCCAAGAGGCGCGGTATCGCAGGCGATTTCACCGTGTTCAAATGCGCGTCC
GCCGCCGCGGAGGAGGGTCTCGACCTCGCCGGCGTGGTGCGGGTGGCCGAGGCGTCCAACGCGGCGACCCGCACGCTGGG
CGTCGCGTTCGACGGCTGCACGCTCCCCGGCGCGGACCATCCGCTGTTCACGGTGCCCGAGGGACAGATGGGCGTCGGCC
TGGGAATCCACGGTGAGCCCGGCGTCGCCGAGAAGGCCATGCCCACCGCCGCCGGTCTGGCCGGCACCCTCGTCGACGGT
GTGCTCGGTGATGCCCCAGCGGACGCCGCGTCGAAGCGAATCGCGGTGATCCTCAACGGACTCGGGCGCACCAAGTACGA
AGAGCTGTTCGTCGTATGGGGGGAGGTGGCGCGGCTGCTGCGGGACCGCGGCTACGAGATCGTCGAACCCGAGGTCGGTG
AGCTCGTCACCAGCCTCGACATGGCCGGCTGCTCGTTGACAGTCATGTGGCTCGACGACGAACTCGAGCGGTACTGGCGG
GCACCCGCGGACACCCCGGCCTACCGCAAAGGTGGTGCGGCAGTTGATAACTCAGGTGAACGGCGCAGCGATGCCGACAT
CCGGACGGCCACCGCCGCACCCGCGGTCGGTGAGCGGTCCGACGACGCCGGACGTGACGGCGGCCGGACGGTCGCCCGGA
TCTTCGAGGCCCTGGCCGCGATGCTCGCCGACGCCGAGGACGAACTCGGCCGCATCGACGCGATCGCCGGTGACGGCGAC
CACGGCCGCGGCATGGTGAAGGGTTCGGCGGCGGCCCGGGCCGCGGCCGCCGAAGCGGTCGAGCAGGGCGCCGGGCAGGG
TTCGGTGCTCGCCGCGGCCGGTAAGGAGTGGGCGGCCAAGGCCGGCGGCACATCCGGGGTTCTGTGGGGTGCGCTGCTCA
GCGCGTTGGGCACCCGCCTGGGCGACACCGGCCGGCCGGACGCGGCGACGGTCGCCGCGGGTATGCGGGACGGTTACGAC
GCGCTGGTCCAGCTGGGCGGCGCCGCACCCGGTGACAAGACGATGCTCGACGCACTGTGGCCGTTCGTCGAGGAACTCGA
GCGGCGCGTCTCCGACGGGGAGCGCTGGCAGCAGGCCTGGGCGGTGGCCGCGCAGACGGCGGAGGACGCCGCACGCGCCA
CCGCCGATCTGCGACCCAGGGTGGGCCGGGCCCGCCCACTGGCCGAACGCAGCATCGGGACCCCCGACGCCGGCGCGACC
TCGCTGGCGATGTGCGCGCGCACGGTCGCCGAAAGCCTCAGCGTGAAAGGGGACAGTCGGCAATGA

Upstream 100 bases:

>100_bases
CACCGGCCGCCGAGAGCTACGAACCCGAACAGAAGGTGATCGTCACGGCGGCGCCGGAACGGGTCTACCTGTTCGACACC
GAGACAGGGGAGCGTCTGCG

Downstream 100 bases:

>100_bases
CGGCGCAACAGACGTCCAAACTCCGCATCGTCGTCGGATCCGACGACGCCGGCTACGAATACAAGGAAGCCCTCAAGGGG
GACCTGAAAGCAGACGACCG

Product: dihydroxyacetone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 581; Mature: 580

Protein sequence:

>581_residues
MTKLFNDPARFTEDMLVGFLDANSRYVAGVPGGVVRAHETRPGKVAVVIGGGSGHYPAFCGTVGPGFADGAVVGNIFTSP
STEEAASVARAAHGDAGVLLITGNYAGDVMNFGLAVTALRGEGVDAHYFAVTDDIASAPKGEEAKRRGIAGDFTVFKCAS
AAAEEGLDLAGVVRVAEASNAATRTLGVAFDGCTLPGADHPLFTVPEGQMGVGLGIHGEPGVAEKAMPTAAGLAGTLVDG
VLGDAPADAASKRIAVILNGLGRTKYEELFVVWGEVARLLRDRGYEIVEPEVGELVTSLDMAGCSLTVMWLDDELERYWR
APADTPAYRKGGAAVDNSGERRSDADIRTATAAPAVGERSDDAGRDGGRTVARIFEALAAMLADAEDELGRIDAIAGDGD
HGRGMVKGSAAARAAAAEAVEQGAGQGSVLAAAGKEWAAKAGGTSGVLWGALLSALGTRLGDTGRPDAATVAAGMRDGYD
ALVQLGGAAPGDKTMLDALWPFVEELERRVSDGERWQQAWAVAAQTAEDAARATADLRPRVGRARPLAERSIGTPDAGAT
SLAMCARTVAESLSVKGDSRQ

Sequences:

>Translated_581_residues
MTKLFNDPARFTEDMLVGFLDANSRYVAGVPGGVVRAHETRPGKVAVVIGGGSGHYPAFCGTVGPGFADGAVVGNIFTSP
STEEAASVARAAHGDAGVLLITGNYAGDVMNFGLAVTALRGEGVDAHYFAVTDDIASAPKGEEAKRRGIAGDFTVFKCAS
AAAEEGLDLAGVVRVAEASNAATRTLGVAFDGCTLPGADHPLFTVPEGQMGVGLGIHGEPGVAEKAMPTAAGLAGTLVDG
VLGDAPADAASKRIAVILNGLGRTKYEELFVVWGEVARLLRDRGYEIVEPEVGELVTSLDMAGCSLTVMWLDDELERYWR
APADTPAYRKGGAAVDNSGERRSDADIRTATAAPAVGERSDDAGRDGGRTVARIFEALAAMLADAEDELGRIDAIAGDGD
HGRGMVKGSAAARAAAAEAVEQGAGQGSVLAAAGKEWAAKAGGTSGVLWGALLSALGTRLGDTGRPDAATVAAGMRDGYD
ALVQLGGAAPGDKTMLDALWPFVEELERRVSDGERWQQAWAVAAQTAEDAARATADLRPRVGRARPLAERSIGTPDAGAT
SLAMCARTVAESLSVKGDSRQ
>Mature_580_residues
TKLFNDPARFTEDMLVGFLDANSRYVAGVPGGVVRAHETRPGKVAVVIGGGSGHYPAFCGTVGPGFADGAVVGNIFTSPS
TEEAASVARAAHGDAGVLLITGNYAGDVMNFGLAVTALRGEGVDAHYFAVTDDIASAPKGEEAKRRGIAGDFTVFKCASA
AAEEGLDLAGVVRVAEASNAATRTLGVAFDGCTLPGADHPLFTVPEGQMGVGLGIHGEPGVAEKAMPTAAGLAGTLVDGV
LGDAPADAASKRIAVILNGLGRTKYEELFVVWGEVARLLRDRGYEIVEPEVGELVTSLDMAGCSLTVMWLDDELERYWRA
PADTPAYRKGGAAVDNSGERRSDADIRTATAAPAVGERSDDAGRDGGRTVARIFEALAAMLADAEDELGRIDAIAGDGDH
GRGMVKGSAAARAAAAEAVEQGAGQGSVLAAAGKEWAAKAGGTSGVLWGALLSALGTRLGDTGRPDAATVAAGMRDGYDA
LVQLGGAAPGDKTMLDALWPFVEELERRVSDGERWQQAWAVAAQTAEDAARATADLRPRVGRARPLAERSIGTPDAGATS
LAMCARTVAESLSVKGDSRQ

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=567, Percent_Identity=33.3333333333333, Blast_Score=236, Evalue=5e-62,
Organism=Escherichia coli, GI87081857, Length=355, Percent_Identity=33.8028169014084, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1787449, Length=179, Percent_Identity=31.8435754189944, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17565018, Length=585, Percent_Identity=30.9401709401709, Blast_Score=220, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6321055, Length=553, Percent_Identity=31.1030741410488, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6323570, Length=602, Percent_Identity=29.2358803986711, Blast_Score=169, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 59474; Mature: 59343

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLFNDPARFTEDMLVGFLDANSRYVAGVPGGVVRAHETRPGKVAVVIGGGSGHYPAFC
CCCCCCCHHHHHHHHHEEEECCCCCEEECCCCCEEEECCCCCCEEEEEEECCCCCCCEEE
GTVGPGFADGAVVGNIFTSPSTEEAASVARAAHGDAGVLLITGNYAGDVMNFGLAVTALR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHCCEEEEEEE
GEGVDAHYFAVTDDIASAPKGEEAKRRGIAGDFTVFKCASAAAEEGLDLAGVVRVAEASN
CCCCCEEEEEEEHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
AATRTLGVAFDGCTLPGADHPLFTVPEGQMGVGLGIHGEPGVAEKAMPTAAGLAGTLVDG
CHHHEEEEEECCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCHHCCCHHHHHHHHHHHH
VLGDAPADAASKRIAVILNGLGRTKYEELFVVWGEVARLLRDRGYEIVEPEVGELVTSLD
HHCCCCCHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHH
MAGCSLTVMWLDDELERYWRAPADTPAYRKGGAAVDNSGERRSDADIRTATAAPAVGERS
CCCCEEEEEEECHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
DDAGRDGGRTVARIFEALAAMLADAEDELGRIDAIAGDGDHGRGMVKGSAAARAAAAEAV
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCEEEECCCCCCCCCEEECHHHHHHHHHHHH
EQGAGQGSVLAAAGKEWAAKAGGTSGVLWGALLSALGTRLGDTGRPDAATVAAGMRDGYD
HHCCCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHH
ALVQLGGAAPGDKTMLDALWPFVEELERRVSDGERWQQAWAVAAQTAEDAARATADLRPR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VGRARPLAERSIGTPDAGATSLAMCARTVAESLSVKGDSRQ
CCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TKLFNDPARFTEDMLVGFLDANSRYVAGVPGGVVRAHETRPGKVAVVIGGGSGHYPAFC
CCCCCCHHHHHHHHHEEEECCCCCEEECCCCCEEEECCCCCCEEEEEEECCCCCCCEEE
GTVGPGFADGAVVGNIFTSPSTEEAASVARAAHGDAGVLLITGNYAGDVMNFGLAVTALR
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCEEEEECCCCCHHHHCCEEEEEEE
GEGVDAHYFAVTDDIASAPKGEEAKRRGIAGDFTVFKCASAAAEEGLDLAGVVRVAEASN
CCCCCEEEEEEEHHHHCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCC
AATRTLGVAFDGCTLPGADHPLFTVPEGQMGVGLGIHGEPGVAEKAMPTAAGLAGTLVDG
CHHHEEEEEECCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCHHCCCHHHHHHHHHHHH
VLGDAPADAASKRIAVILNGLGRTKYEELFVVWGEVARLLRDRGYEIVEPEVGELVTSLD
HHCCCCCHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHH
MAGCSLTVMWLDDELERYWRAPADTPAYRKGGAAVDNSGERRSDADIRTATAAPAVGERS
CCCCEEEEEEECHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCC
DDAGRDGGRTVARIFEALAAMLADAEDELGRIDAIAGDGDHGRGMVKGSAAARAAAAEAV
CCCCCCCHHHHHHHHHHHHHHHHCCHHHHCCEEEECCCCCCCCCEEECHHHHHHHHHHHH
EQGAGQGSVLAAAGKEWAAKAGGTSGVLWGALLSALGTRLGDTGRPDAATVAAGMRDGYD
HHCCCCCCEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHH
ALVQLGGAAPGDKTMLDALWPFVEELERRVSDGERWQQAWAVAAQTAEDAARATADLRPR
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VGRARPLAERSIGTPDAGATSLAMCARTVAESLSVKGDSRQ
CCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA