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The map label for this gene is cyp144 [H]

Identifier: 119868624

GI number: 119868624

Start: 2721792

End: 2723063

Strand: Direct

Name: cyp144 [H]

Synonym: Mkms_2589

Alternate gene names: 119868624

Gene position: 2721792-2723063 (Clockwise)

Preceding gene: 119868623

Following gene: 119868625

Centisome position: 47.44

GC content: 63.84

Gene sequence:

>1272_bases
GTGAGCGATTTCGAGTCGGTCGACTACTTCACCGACATGTCCCTGGTCCCCGACCCGTACCCCTACTTCGACTACCTGCG
AGCCAAGTGCCCGGTACAGCGGGCCACTCCGTACGGCGTGATGGCGGTGACGGGACACCAGGAAGCTCTGGCGGCGTACA
AGGACCCCGCGATGTCCTCGTGTGTCGCCGTGGCGGGACCGTTTCCGCCGCTGCCGTTCACACCGGAAGGCGACGACATC
ACCGCGCAGATCGAGGAGCACCGAACTGCCATCCCGATGGCTGAGCATGTGGTGACGATGGACGCTGAGCAGCATGCGAG
AACCCGCGGCCTGTTGAGCAAGCTGATCACCCCGAAACGGCTTGCCGAAAATCAAGATTTCATGTGGCGACTGGTCGACC
GGCAGATCGACAAGTTCCTCGAGCGTGGATCCTGCGAGTTCATGACGGACTTCGCGAAACCGCTGTCGATGCTGGTGATC
GCGGACCTGCTCGGTGTTCCTCTCGAGGACCACGACGAATTCAGGCGGGCCCTCGGCGACGAGGTCGTCGGCGACATCGG
CGCCGAGGACACCGTTGCGCACAACCCGCTGATGTGGCTGGACGAAAAGTTCGCCTCATATGTCATCGACCGCAGGCGCG
AACCTCGCGAGGACGTGTTGACCGAACTGGCTGCGGCGACGTACCCGGACGGATCGGTCCCGGATGTCGACGAGGTCGTC
AAACTCGCGACATTCCTGTTCGCGGCCGGAATGGAGACGACGACAAAGCTTCTCAGCACCGCGATGCGGGTGATGGGCGA
GCGCCCCGACATCCAACAGGTTCTTCGCGATGAGCGGACCCGCATACCGACATTCCTCGAAGAGTGTCTGCGGACGGAGA
GCCCGGTCAAGAGCCACTTCCGATTGGCGCGCACCACGACGACGCTCGGTGACGCGGACATTCCAGCCGGCACCATCGTC
ATGCTGCTACCCGGTGCCAGCAACCGTGACCCACGCAAGTTCGAGAATCCACACGAGTTCCGGCCCGACCGAAGCAATGT
GCGTGAGCACGTCGCCTTCGGACGCGGGCCGCACTCATGTCCCGGCGCGCCGTTGGCACGCGCCGAAGCGCGCATCTCGA
TGAACCGCCTGCTGGACCGCATGGCGAACATCCGCATCTCCGAAGAGATGCACGGGCCCGCCGGTGAGCGGAAGTACGAG
TACGACCCGACGTTCATCATGCGGGGGCTCTCGGCTCTGCACATCGAGTTCGAACCCCTGCCGGACCCCTGA

Upstream 100 bases:

>100_bases
GATCGTTCACACCGCGTGTGACGCGTTCGGTCGACTCGGTGTCTACCAACCTGCTTTTGTCCTGCGACAGCCGGGCGTCA
GTGCCCATTAGGGAGGCAAT

Downstream 100 bases:

>100_bases
GGGTGTACGAGAGGTGAGCGATGAAGCGCCTCAACGGGATGGACGCGCTGCTGCTCTACAGCGAAACGCCCAACGTCCAC
ACCCACACGCTCAAGATCGC

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MSDFESVDYFTDMSLVPDPYPYFDYLRAKCPVQRATPYGVMAVTGHQEALAAYKDPAMSSCVAVAGPFPPLPFTPEGDDI
TAQIEEHRTAIPMAEHVVTMDAEQHARTRGLLSKLITPKRLAENQDFMWRLVDRQIDKFLERGSCEFMTDFAKPLSMLVI
ADLLGVPLEDHDEFRRALGDEVVGDIGAEDTVAHNPLMWLDEKFASYVIDRRREPREDVLTELAAATYPDGSVPDVDEVV
KLATFLFAAGMETTTKLLSTAMRVMGERPDIQQVLRDERTRIPTFLEECLRTESPVKSHFRLARTTTTLGDADIPAGTIV
MLLPGASNRDPRKFENPHEFRPDRSNVREHVAFGRGPHSCPGAPLARAEARISMNRLLDRMANIRISEEMHGPAGERKYE
YDPTFIMRGLSALHIEFEPLPDP

Sequences:

>Translated_423_residues
MSDFESVDYFTDMSLVPDPYPYFDYLRAKCPVQRATPYGVMAVTGHQEALAAYKDPAMSSCVAVAGPFPPLPFTPEGDDI
TAQIEEHRTAIPMAEHVVTMDAEQHARTRGLLSKLITPKRLAENQDFMWRLVDRQIDKFLERGSCEFMTDFAKPLSMLVI
ADLLGVPLEDHDEFRRALGDEVVGDIGAEDTVAHNPLMWLDEKFASYVIDRRREPREDVLTELAAATYPDGSVPDVDEVV
KLATFLFAAGMETTTKLLSTAMRVMGERPDIQQVLRDERTRIPTFLEECLRTESPVKSHFRLARTTTTLGDADIPAGTIV
MLLPGASNRDPRKFENPHEFRPDRSNVREHVAFGRGPHSCPGAPLARAEARISMNRLLDRMANIRISEEMHGPAGERKYE
YDPTFIMRGLSALHIEFEPLPDP
>Mature_422_residues
SDFESVDYFTDMSLVPDPYPYFDYLRAKCPVQRATPYGVMAVTGHQEALAAYKDPAMSSCVAVAGPFPPLPFTPEGDDIT
AQIEEHRTAIPMAEHVVTMDAEQHARTRGLLSKLITPKRLAENQDFMWRLVDRQIDKFLERGSCEFMTDFAKPLSMLVIA
DLLGVPLEDHDEFRRALGDEVVGDIGAEDTVAHNPLMWLDEKFASYVIDRRREPREDVLTELAAATYPDGSVPDVDEVVK
LATFLFAAGMETTTKLLSTAMRVMGERPDIQQVLRDERTRIPTFLEECLRTESPVKSHFRLARTTTTLGDADIPAGTIVM
LLPGASNRDPRKFENPHEFRPDRSNVREHVAFGRGPHSCPGAPLARAEARISMNRLLDRMANIRISEEMHGPAGERKYEY
DPTFIMRGLSALHIEFEPLPDP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI310125130, Length=211, Percent_Identity=31.2796208530806, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI190570174, Length=211, Percent_Identity=31.2796208530806, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI310125128, Length=211, Percent_Identity=31.2796208530806, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI14550409, Length=211, Percent_Identity=31.2796208530806, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24656064, Length=232, Percent_Identity=26.2931034482759, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 47575; Mature: 47443

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFESVDYFTDMSLVPDPYPYFDYLRAKCPVQRATPYGVMAVTGHQEALAAYKDPAMSS
CCCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHH
CVAVAGPFPPLPFTPEGDDITAQIEEHRTAIPMAEHVVTMDAEQHARTRGLLSKLITPKR
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHEECCHHHHHHHHHHHHHHCCHHH
LAENQDFMWRLVDRQIDKFLERGSCEFMTDFAKPLSMLVIADLLGVPLEDHDEFRRALGD
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EVVGDIGAEDTVAHNPLMWLDEKFASYVIDRRREPREDVLTELAAATYPDGSVPDVDEVV
HHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
KLATFLFAAGMETTTKLLSTAMRVMGERPDIQQVLRDERTRIPTFLEECLRTESPVKSHF
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
RLARTTTTLGDADIPAGTIVMLLPGASNRDPRKFENPHEFRPDRSNVREHVAFGRGPHSC
HHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
PGAPLARAEARISMNRLLDRMANIRISEEMHGPAGERKYEYDPTFIMRGLSALHIEFEPL
CCCCHHHHHHHHHHHHHHHHHHCCEECHHHCCCCCCCCCCCCHHHHHHCCHHEEEEECCC
PDP
CCC
>Mature Secondary Structure 
SDFESVDYFTDMSLVPDPYPYFDYLRAKCPVQRATPYGVMAVTGHQEALAAYKDPAMSS
CCCHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHH
CVAVAGPFPPLPFTPEGDDITAQIEEHRTAIPMAEHVVTMDAEQHARTRGLLSKLITPKR
HHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHEECCHHHHHHHHHHHHHHCCHHH
LAENQDFMWRLVDRQIDKFLERGSCEFMTDFAKPLSMLVIADLLGVPLEDHDEFRRALGD
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
EVVGDIGAEDTVAHNPLMWLDEKFASYVIDRRREPREDVLTELAAATYPDGSVPDVDEVV
HHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
KLATFLFAAGMETTTKLLSTAMRVMGERPDIQQVLRDERTRIPTFLEECLRTESPVKSHF
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHH
RLARTTTTLGDADIPAGTIVMLLPGASNRDPRKFENPHEFRPDRSNVREHVAFGRGPHSC
HHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
PGAPLARAEARISMNRLLDRMANIRISEEMHGPAGERKYEYDPTFIMRGLSALHIEFEPL
CCCCHHHHHHHHHHHHHHHHHHCCEECHHHCCCCCCCCCCCCHHHHHHCCHHEEEEECCC
PDP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]