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The map label for this gene is yusZ [H]

Identifier: 119868621

GI number: 119868621

Start: 2717839

End: 2718885

Strand: Direct

Name: yusZ [H]

Synonym: Mkms_2586

Alternate gene names: 119868621

Gene position: 2717839-2718885 (Clockwise)

Preceding gene: 119868620

Following gene: 119868622

Centisome position: 47.37

GC content: 66.86

Gene sequence:

>1047_bases
TTGAGAACCAGAATGGGTGAGCCGCGCCGCCGCGACGAGCGGACAGTCGTCATCACGGGTGCATCGCGCGGACTTGGTTT
CGCCTCGGCCGTACGCCTCTACCGCGAGGGGTGGCGCGTGGTGGCCGCGATGCGCACACCCGGTGAGTGCGCTGCGTTAC
TACGCGAGGCCGCCGGAGCCACCGATGACGACGACCGTCTGGTCTGCGTGCAACTCGACCTCATGGACACGGCCTCGGTC
GCCGCGGCGGCCAAGTTGATCGAGGAGGCCGTCGGCGCACCATATGCCCTGGTGCACAACGCCGGGATCTCCGCTGCAGG
GGTGGTGGAGGAGACCGACATCGAGTTGTGGCAGAAGATGTTCGCGACGCACGTGATGGGTCCGGTCGCGCTGACGAAGG
CGTTGCTCCCGTCGATGCGCGCGGCGGGCCGCGGGCGAATCGTACTCGTGTCGAGTGCAGGTGGAGTGCGAGGCCAGCCG
GCCATCGCACCGTACTCGGCGGCGAAGGGGGCGCTGGAGCGTTGGGGTGAGTCGATGGCGGGGGAGATCGCACCGTTCGG
TCTCGGCGTGACCGTTCTGGTGACCGGTACCTACGACACCGACATCATCACCGACGCGGGGACCACCGACGACCGGAACT
TCGAAGGGCCGTATGCCCGCATCCATGCCACCATGAACACCCGCGGGCGGTTCGCGATGCGGTTGGCGCGGCCACCGGAA
CGATTCACCGACGGACTGGTCAAGGCGTTGGCGGACGAGAAACCGTTCCGCCGTCGGGGTGTCGGGCCCGACGCATCCAT
GCTGTTGATGTTCAACCGGATTCTCCCGGCCGCGGGAATGCACCACATGTCGAGGCTCGTGATGGGAATCCCTCGGCAGG
GTGCCATGACGGACGGGGCCTACCCGTTGACGACTGCGCAGAAGGCAATGGTGTTCGCGGCCAAGGTGCTTCCCCAGCCT
GTTCTCATGCGGTTGGTGTCGCTGGCCACGCGGCTCACGCCCACCAAGGAGGAACCTCGACAAGAGGGGAGTGCCAACGA
TGCCTGA

Upstream 100 bases:

>100_bases
GGGCCATTCTCGGTCGGCATCTGGTCGACGTGGATGAGCGGGCAACCCGACGGGCGGCCCGACGTCGAGCCTCCGCCACC
GGGCGAAGGTGCCTGCGCAG

Downstream 100 bases:

>100_bases
TGTGAATGTGACGTCCGAGTCGAGGATGTTGATCGACGGCAAACTCGTCGACGGTGAGGCGGGAACCTTCATCAATGTCA
ACCCGGCGAACGAGGAGGTG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: ORFA [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRTRMGEPRRRDERTVVITGASRGLGFASAVRLYREGWRVVAAMRTPGECAALLREAAGATDDDDRLVCVQLDLMDTASV
AAAAKLIEEAVGAPYALVHNAGISAAGVVEETDIELWQKMFATHVMGPVALTKALLPSMRAAGRGRIVLVSSAGGVRGQP
AIAPYSAAKGALERWGESMAGEIAPFGLGVTVLVTGTYDTDIITDAGTTDDRNFEGPYARIHATMNTRGRFAMRLARPPE
RFTDGLVKALADEKPFRRRGVGPDASMLLMFNRILPAAGMHHMSRLVMGIPRQGAMTDGAYPLTTAQKAMVFAAKVLPQP
VLMRLVSLATRLTPTKEEPRQEGSANDA

Sequences:

>Translated_348_residues
MRTRMGEPRRRDERTVVITGASRGLGFASAVRLYREGWRVVAAMRTPGECAALLREAAGATDDDDRLVCVQLDLMDTASV
AAAAKLIEEAVGAPYALVHNAGISAAGVVEETDIELWQKMFATHVMGPVALTKALLPSMRAAGRGRIVLVSSAGGVRGQP
AIAPYSAAKGALERWGESMAGEIAPFGLGVTVLVTGTYDTDIITDAGTTDDRNFEGPYARIHATMNTRGRFAMRLARPPE
RFTDGLVKALADEKPFRRRGVGPDASMLLMFNRILPAAGMHHMSRLVMGIPRQGAMTDGAYPLTTAQKAMVFAAKVLPQP
VLMRLVSLATRLTPTKEEPRQEGSANDA
>Mature_348_residues
MRTRMGEPRRRDERTVVITGASRGLGFASAVRLYREGWRVVAAMRTPGECAALLREAAGATDDDDRLVCVQLDLMDTASV
AAAAKLIEEAVGAPYALVHNAGISAAGVVEETDIELWQKMFATHVMGPVALTKALLPSMRAAGRGRIVLVSSAGGVRGQP
AIAPYSAAKGALERWGESMAGEIAPFGLGVTVLVTGTYDTDIITDAGTTDDRNFEGPYARIHATMNTRGRFAMRLARPPE
RFTDGLVKALADEKPFRRRGVGPDASMLLMFNRILPAAGMHHMSRLVMGIPRQGAMTDGAYPLTTAQKAMVFAAKVLPQP
VLMRLVSLATRLTPTKEEPRQEGSANDA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=202, Percent_Identity=36.1386138613861, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI7657478, Length=192, Percent_Identity=34.8958333333333, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI223718074, Length=253, Percent_Identity=30.8300395256917, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI44680136, Length=189, Percent_Identity=30.6878306878307, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI44680133, Length=189, Percent_Identity=30.6878306878307, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI17738292, Length=189, Percent_Identity=30.6878306878307, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI4503817, Length=179, Percent_Identity=27.9329608938547, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=31.4432989690722, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI119392083, Length=298, Percent_Identity=26.1744966442953, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI19743808, Length=281, Percent_Identity=28.4697508896797, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI40548397, Length=209, Percent_Identity=28.7081339712919, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI214010158, Length=209, Percent_Identity=28.7081339712919, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI214010156, Length=209, Percent_Identity=28.7081339712919, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI22758144, Length=209, Percent_Identity=28.7081339712919, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI22507405, Length=275, Percent_Identity=28.3636363636364, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI50726952, Length=297, Percent_Identity=27.6094276094276, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI157739938, Length=193, Percent_Identity=27.979274611399, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI150247226, Length=198, Percent_Identity=35.8585858585859, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI32483357, Length=210, Percent_Identity=30, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI5031737, Length=238, Percent_Identity=28.1512605042017, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=30.8900523560209, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI126723191, Length=209, Percent_Identity=28.7081339712919, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI146231950, Length=149, Percent_Identity=37.5838926174497, Blast_Score=65, Evalue=7e-11,
Organism=Homo sapiens, GI40254992, Length=193, Percent_Identity=29.0155440414508, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1786701, Length=266, Percent_Identity=29.3233082706767, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787335, Length=199, Percent_Identity=30.6532663316583, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082100, Length=184, Percent_Identity=32.6086956521739, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=286, Percent_Identity=26.2237762237762, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563809, Length=286, Percent_Identity=26.2237762237762, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17557780, Length=197, Percent_Identity=29.9492385786802, Blast_Score=78, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=29.8969072164948, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534660, Length=289, Percent_Identity=23.8754325259516, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17568967, Length=201, Percent_Identity=29.3532338308458, Blast_Score=69, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=189, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=204, Percent_Identity=26.9607843137255, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24651139, Length=268, Percent_Identity=28.7313432835821, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=33.502538071066, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI21356301, Length=192, Percent_Identity=31.25, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=200, Percent_Identity=31.5, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI23397609, Length=208, Percent_Identity=30.2884615384615, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21355319, Length=199, Percent_Identity=30.6532663316583, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24641232, Length=209, Percent_Identity=31.1004784688995, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI21357041, Length=198, Percent_Identity=28.2828282828283, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI116007236, Length=197, Percent_Identity=30.4568527918782, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648944, Length=199, Percent_Identity=29.1457286432161, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI116007238, Length=187, Percent_Identity=31.0160427807487, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37272; Mature: 37272

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00061 ADH_SHORT ; PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTRMGEPRRRDERTVVITGASRGLGFASAVRLYREGWRVVAAMRTPGECAALLREAAGA
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCC
TDDDDRLVCVQLDLMDTASVAAAAKLIEEAVGAPYALVHNAGISAAGVVEETDIELWQKM
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHHH
FATHVMGPVALTKALLPSMRAAGRGRIVLVSSAGGVRGQPAIAPYSAAKGALERWGESMA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GEIAPFGLGVTVLVTGTYDTDIITDAGTTDDRNFEGPYARIHATMNTRGRFAMRLARPPE
CCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCHH
RFTDGLVKALADEKPFRRRGVGPDASMLLMFNRILPAAGMHHMSRLVMGIPRQGAMTDGA
HHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
YPLTTAQKAMVFAAKVLPQPVLMRLVSLATRLTPTKEEPRQEGSANDA
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MRTRMGEPRRRDERTVVITGASRGLGFASAVRLYREGWRVVAAMRTPGECAALLREAAGA
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCC
TDDDDRLVCVQLDLMDTASVAAAAKLIEEAVGAPYALVHNAGISAAGVVEETDIELWQKM
CCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHHH
FATHVMGPVALTKALLPSMRAAGRGRIVLVSSAGGVRGQPAIAPYSAAKGALERWGESMA
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GEIAPFGLGVTVLVTGTYDTDIITDAGTTDDRNFEGPYARIHATMNTRGRFAMRLARPPE
CCCCCCCCCEEEEEECCCCCCEEECCCCCCCCCCCCCCEEEEEEECCCCCEEEEECCCHH
RFTDGLVKALADEKPFRRRGVGPDASMLLMFNRILPAAGMHHMSRLVMGIPRQGAMTDGA
HHHHHHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
YPLTTAQKAMVFAAKVLPQPVLMRLVSLATRLTPTKEEPRQEGSANDA
CCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9384377; 8396117 [H]