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The map label for this gene is norD [H]

Identifier: 119868617

GI number: 119868617

Start: 2712807

End: 2714522

Strand: Direct

Name: norD [H]

Synonym: Mkms_2582

Alternate gene names: 119868617

Gene position: 2712807-2714522 (Clockwise)

Preceding gene: 119868612

Following gene: 119868618

Centisome position: 47.28

GC content: 68.71

Gene sequence:

>1716_bases
TTGGTCAACGAGGGCGCGGAGGTCACGGTGGCAGACGACGTCGACGACGGCAGCCTTCGGGGCCTGGGCATGTTGGCATC
GGTGCTCGCGGGTCAACCGGTGGCGGTGGCCCCGCTGCCGGCAGGAGAGCCATCGTGGACCGACGGGCAGACCGTGTTCG
TCGATCCGACCGCAGGCGGTCGCGCGAATCTCGATTCGGTTGCGGTGCACGCGTCGCTGATAGCTGCGGGCAGCCTCGAC
TCCGAGATCATGGCGAAGCTGGTCATGCGTCCTCGGATAGCCAGGCGGTATGCGGCCGTCGAAGGTCATCGGGCGCTGTT
CGCCAACCGGGATCTGCTGCCGGGCGCGCTGGCCTCGCTGGCCGACCCGCACGTCGCGGGCCGCAGCGATTCGCCGGCGG
CGTCGTTGTCACTGGCGTCGGGCAAGGAGGCGCTCGACGAGGCCCCTGCGGTGTTCGGTGTCGTCCGTGCCAGGAAGGTC
ATCGCCGCGAACAGCAAGGCTGCCGTGCAGGCCGACCACGACACCGTTGGCCATGTCCCGCGTCGGGAGGGCACGGAGGA
TCTCGAAGAACTCGACGATGGCGAGGTGGACGACACTGACGACCCGGATCTGTTCACCAGTCCCGTCGGCGGTGGGGGCT
CCATCGGAAAGTGGTTGAAGAAGCTGCTGTCGTCGGCGCGCAAGAGCGGCGGCAGCGGTGGCGGTCCACCCGGTGCTGAT
TCACCCACCCACCGGACGAATTCGGCGAACCGAGGCGCCTACGCGGTGTCGTCGACGGCCACGGCATCCGGTGACGACGT
CCCCGATGTCACGACCGACGGCCTGAAGTATCCCGAGTGGGACGGGAAACGCAAGGCGTACCGACCCGACTGGTGCACGG
TCCGTGAAGTCGAAGCGCGAATCAAAGCCTCGGCTCCCCAGGCGATCGAGAGTGCCGTCAATGTGCGTAGGCCGCTGGCC
CGACTGGGGATGGGGCTGCACCGGCGGCACCGGCAGTTCCAAGGCGATGACATAGACATCGACGCGGCCATCGAAGCGCG
CGTGGAGGTGATCGCGGGATCGGTGGCCGACGAGGCCGTCTACCTCGACAGCCTGCGTCGGCGTCGTGATCTGTCCGTTC
TCCTCCTGCTGGACGTCTCGGGATCGACAGCTGAGCCCGGGACCGTCGGCCGAACGGTGCATCAGCAGCAACGCACCGCG
GTCGCGAACCTCACGGTCGCACTCAACGACCTCGGCGACCGGGTCGCGCTGTACGCCTACTACTCACAGGGGCGCACCGC
GGTCACCATGGTGCCCGTCAAGCGGTTCGACGATCACCTCGACGCGAGGGTCGTCAGGCGGTTGAACAGCTTGGAACCGG
GTGCCTACTCCCGGCTGGGCGCCGCGATCCGCCACGGGTCGGCTGTCCTGGAGTCCCGCGGCGGAACGTCGCGCCGACTG
TTGGTGGTGATCTCCGACGGGCTTGCCTACGACCACGGCTACGAGCGGGCATACGGGGCTGCTGATGCCAGACGTGCGCT
GACGGAGGCCCGCCGCCGCGGTACGGGGTGCGTCTGCCTCACCATCGGCGCGAGCACGGACGTGGCGTCGCTGCAACGGG
TGTTCGGCAGCGCGGCGCACGCGACGATCGCCGGTCCGGACCAACTCGCCGGTGTGGTCGGCCCCCTTTTCCGGTCGGCC
CTTCGTTCTGCGGAGGTACGGCGTCGTGTGTCGTAG

Upstream 100 bases:

>100_bases
GAAATTGTTCAGCTTCTTGCGGGTATGAGAAATCCACGCTCTCCAACCGACCTCGTTCGATTGACTCCGATGAGACCGAA
CTCTACGGTGGAACAGATAT

Downstream 100 bases:

>100_bases
TAGATCGGGAAAGTTCGTGCTTATCGCAAGTCGCAGAACGCAGTACGCCGACAAGGCGCGCATCCGCAGGTATTGAAACA
AACATCTGTTCCGCATTAGG

Product: von Willebrand factor, type A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 571; Mature: 571

Protein sequence:

>571_residues
MVNEGAEVTVADDVDDGSLRGLGMLASVLAGQPVAVAPLPAGEPSWTDGQTVFVDPTAGGRANLDSVAVHASLIAAGSLD
SEIMAKLVMRPRIARRYAAVEGHRALFANRDLLPGALASLADPHVAGRSDSPAASLSLASGKEALDEAPAVFGVVRARKV
IAANSKAAVQADHDTVGHVPRREGTEDLEELDDGEVDDTDDPDLFTSPVGGGGSIGKWLKKLLSSARKSGGSGGGPPGAD
SPTHRTNSANRGAYAVSSTATASGDDVPDVTTDGLKYPEWDGKRKAYRPDWCTVREVEARIKASAPQAIESAVNVRRPLA
RLGMGLHRRHRQFQGDDIDIDAAIEARVEVIAGSVADEAVYLDSLRRRRDLSVLLLLDVSGSTAEPGTVGRTVHQQQRTA
VANLTVALNDLGDRVALYAYYSQGRTAVTMVPVKRFDDHLDARVVRRLNSLEPGAYSRLGAAIRHGSAVLESRGGTSRRL
LVVISDGLAYDHGYERAYGAADARRALTEARRRGTGCVCLTIGASTDVASLQRVFGSAAHATIAGPDQLAGVVGPLFRSA
LRSAEVRRRVS

Sequences:

>Translated_571_residues
MVNEGAEVTVADDVDDGSLRGLGMLASVLAGQPVAVAPLPAGEPSWTDGQTVFVDPTAGGRANLDSVAVHASLIAAGSLD
SEIMAKLVMRPRIARRYAAVEGHRALFANRDLLPGALASLADPHVAGRSDSPAASLSLASGKEALDEAPAVFGVVRARKV
IAANSKAAVQADHDTVGHVPRREGTEDLEELDDGEVDDTDDPDLFTSPVGGGGSIGKWLKKLLSSARKSGGSGGGPPGAD
SPTHRTNSANRGAYAVSSTATASGDDVPDVTTDGLKYPEWDGKRKAYRPDWCTVREVEARIKASAPQAIESAVNVRRPLA
RLGMGLHRRHRQFQGDDIDIDAAIEARVEVIAGSVADEAVYLDSLRRRRDLSVLLLLDVSGSTAEPGTVGRTVHQQQRTA
VANLTVALNDLGDRVALYAYYSQGRTAVTMVPVKRFDDHLDARVVRRLNSLEPGAYSRLGAAIRHGSAVLESRGGTSRRL
LVVISDGLAYDHGYERAYGAADARRALTEARRRGTGCVCLTIGASTDVASLQRVFGSAAHATIAGPDQLAGVVGPLFRSA
LRSAEVRRRVS
>Mature_571_residues
MVNEGAEVTVADDVDDGSLRGLGMLASVLAGQPVAVAPLPAGEPSWTDGQTVFVDPTAGGRANLDSVAVHASLIAAGSLD
SEIMAKLVMRPRIARRYAAVEGHRALFANRDLLPGALASLADPHVAGRSDSPAASLSLASGKEALDEAPAVFGVVRARKV
IAANSKAAVQADHDTVGHVPRREGTEDLEELDDGEVDDTDDPDLFTSPVGGGGSIGKWLKKLLSSARKSGGSGGGPPGAD
SPTHRTNSANRGAYAVSSTATASGDDVPDVTTDGLKYPEWDGKRKAYRPDWCTVREVEARIKASAPQAIESAVNVRRPLA
RLGMGLHRRHRQFQGDDIDIDAAIEARVEVIAGSVADEAVYLDSLRRRRDLSVLLLLDVSGSTAEPGTVGRTVHQQQRTA
VANLTVALNDLGDRVALYAYYSQGRTAVTMVPVKRFDDHLDARVVRRLNSLEPGAYSRLGAAIRHGSAVLESRGGTSRRL
LVVISDGLAYDHGYERAYGAADARRALTEARRRGTGCVCLTIGASTDVASLQRVFGSAAHATIAGPDQLAGVVGPLFRSA
LRSAEVRRRVS

Specific function: Part of the operon norEFCBQD encoding nitric oxide reductase. Essential virulence factor, probably involved in the detoxification of nitric oxide (NO) produced in the macrophages during the innate response against infection [H]

COG id: COG4548

COG function: function code P; Nitric oxide reductase activation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 VWFA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002035 [H]

Pfam domain/function: PF00092 VWA [H]

EC number: NA

Molecular weight: Translated: 60066; Mature: 60066

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS50234 VWFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNEGAEVTVADDVDDGSLRGLGMLASVLAGQPVAVAPLPAGEPSWTDGQTVFVDPTAGG
CCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCCC
RANLDSVAVHASLIAAGSLDSEIMAKLVMRPRIARRYAAVEGHRALFANRDLLPGALASL
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHH
ADPHVAGRSDSPAASLSLASGKEALDEAPAVFGVVRARKVIAANSKAAVQADHDTVGHVP
CCCCCCCCCCCCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
RREGTEDLEELDDGEVDDTDDPDLFTSPVGGGGSIGKWLKKLLSSARKSGGSGGGPPGAD
CCCCHHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
SPTHRTNSANRGAYAVSSTATASGDDVPDVTTDGLKYPEWDGKRKAYRPDWCTVREVEAR
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IKASAPQAIESAVNVRRPLARLGMGLHRRHRQFQGDDIDIDAAIEARVEVIAGSVADEAV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHH
YLDSLRRRRDLSVLLLLDVSGSTAEPGTVGRTVHQQQRTAVANLTVALNDLGDRVALYAY
HHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEE
YSQGRTAVTMVPVKRFDDHLDARVVRRLNSLEPGAYSRLGAAIRHGSAVLESRGGTSRRL
ECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHCCCCCCEEE
LVVISDGLAYDHGYERAYGAADARRALTEARRRGTGCVCLTIGASTDVASLQRVFGSAAH
EEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCC
ATIAGPDQLAGVVGPLFRSALRSAEVRRRVS
EEECCHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVNEGAEVTVADDVDDGSLRGLGMLASVLAGQPVAVAPLPAGEPSWTDGQTVFVDPTAGG
CCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCEEEECCCCCC
RANLDSVAVHASLIAAGSLDSEIMAKLVMRPRIARRYAAVEGHRALFANRDLLPGALASL
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHH
ADPHVAGRSDSPAASLSLASGKEALDEAPAVFGVVRARKVIAANSKAAVQADHDTVGHVP
CCCCCCCCCCCCCCEEEHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCC
RREGTEDLEELDDGEVDDTDDPDLFTSPVGGGGSIGKWLKKLLSSARKSGGSGGGPPGAD
CCCCHHHHHHCCCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
SPTHRTNSANRGAYAVSSTATASGDDVPDVTTDGLKYPEWDGKRKAYRPDWCTVREVEAR
CCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IKASAPQAIESAVNVRRPLARLGMGLHRRHRQFQGDDIDIDAAIEARVEVIAGSVADEAV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCHHHHHHH
YLDSLRRRRDLSVLLLLDVSGSTAEPGTVGRTVHQQQRTAVANLTVALNDLGDRVALYAY
HHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCEEEEEEE
YSQGRTAVTMVPVKRFDDHLDARVVRRLNSLEPGAYSRLGAAIRHGSAVLESRGGTSRRL
ECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHCCCCCCEEE
LVVISDGLAYDHGYERAYGAADARRALTEARRRGTGCVCLTIGASTDVASLQRVFGSAAH
EEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCCC
ATIAGPDQLAGVVGPLFRSALRSAEVRRRVS
EEECCHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA