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The map label for this gene is cobIJ [H]

Identifier: 119868567

GI number: 119868567

Start: 2661227

End: 2662714

Strand: Reverse

Name: cobIJ [H]

Synonym: Mkms_2532

Alternate gene names: 119868567

Gene position: 2662714-2661227 (Counterclockwise)

Preceding gene: 119868568

Following gene: 119868566

Centisome position: 46.41

GC content: 71.84

Gene sequence:

>1488_bases
ATGAACCCGCCCATGAAGACGCGCGGCACGCTGTACGGAGTCGGGCTGGGACCCGGCGACCCCGAACTCGTCACCGTCAA
GGCGGCCCGGGTGATCGGGCAGGCCGACGTCGTCGCGTACCACAGTGCACGGCACGGCCGCAGCATCGCGCGCCGCATCG
CCGAGCCCTATCTGCGCGACGGTCAGATCGAGGAGCACCTGGTCTATCCGGTGACCACCGAGGTGACCGACCATCCCGGC
GGTTACGCCGGTGCGATGGAGGACTTCTACCGCGAAGCCGCCGAGCGGATCGCCGCGCATCTGGACGCCGGCCGTGACGT
GGCGTTGCTCGCCGAGGGCGATCCGCTGTTCTACAGCTCCTACATGCACATGCACACCCGGCTCACCGAGCGGTTCACCG
CCGAGATCGTGCCGGGCGTGACGTCGGTGAGTGCGGCGTCGGCGGCCATCGCCACACCGCTGGTCCAGGGCGAAGGGGTG
CTCACGATCCTGCCGGGCACCCTGCCCGCCGACGAACTCGAGCGGCGACTGGCCGACACCGACGCCGCGGTCGTGCTCAA
GCTGGGCCGCTCGTATCCGGCGGTGCGGGCCGCGCTCGCCGCGACCGGCCGGCTCGACGAGGCCTTCTACGTCGAACGCG
CCAGTACCCCCGATCAGCGGACCCTGTCCGCCGCCGACGTCGACGGCGACGACAAGGTGCCGTACTTCTCGTTGGCGATG
ATCCCCGGTGGCGGGCGCCGGCGCGCGGTGACCGGCAGCGTCACCGTCGTCGGGCTGGGCCCCGGCGCGGCGGAGTGGAT
GACCCCGCAGAGCCGCCGTGAACTCGCCGCGGCCACGGATCTGATCGGCTACGGCCCCTACCTCGACCGCGTCGGCCTGC
GGGACGGTCAGCAGCGCCATCCCAGCGACAACACCGACGAACCGGCCCGCGCCCGGCTGGCATGCACGCTCGCCGAACAG
GGGCGCGCCGTGGCGGTGGTGTCCTCCGGCGATCCCGGCGTGTTCGCGATGGCGACCGCCGTCCTCGAGGAGGCCAAGCA
GTGGCCGGGTGTCGAGGTGCGGGTGATCCCGGCGATGACGGCGGCCCAGGCCGTCGCCAGCCGCGTCGGCGCCCCGCTGG
GCCACGACTATGCGGTGATCTCGCTGTCCGACCGGCTCAAACCGTGGGAGATCATCGAAGCCCGGCTGACCGCGGCCGCG
CGGGCCGATCTGGTGCTGGCGATCTACAACCCGGCGTCGAAGACCCGCACCTGGCAGGTCGGCGCGATGCGCGACCTGCT
GCTGGCCCACCGCGATCCCGGCACGCCGGTGGTGATCGGCCGCGACGTCGCGGGACAGCGGGAGCACGTCAAGGTGCTGC
GGTTGGCCGATCTGGACCCCGCCGACGTCGACATGCGGTGTCTGCTGATCGTCGGATCGTCGCAGACCCAGTGGTACAGC
GACGATGCGGGCGATCGGGTCTTCACGCCGCGTTACTACCCGGGGTGA

Upstream 100 bases:

>100_bases
TCGCGCGGCCCCGCGGGATGGCGTACCTGGTGGTGACCGGCCGGCGGGGCGGCAGCGCGATGGCGGCCGCCGCGGTCAAT
GCGATTGCGAGTGAGCGCGA

Downstream 100 bases:

>100_bases
TAGTGTCACGCGTCACACTGTGACGAAAGGCGGTGCCGTGCAGGCCCTCATTCCCGCTAAGCCGGCAGATGTCACCCCGG
AGTGGTTGGGAGCGGCGTTG

Product: cobalt-factor II C20-methyltransferase / precorrin-2 C20-methyltransferase / precorrin-3 methyltransferase

Products: NA

Alternate protein names: Precorrin-2 C(20)-methyltransferase; S-adenosyl-L-methionine--precorrin-2 methyltransferase; SP2MT; Precorrin-3B C17-methyltransferase; S-adenosyl-L-methionine--precorrin-3B methyltransferase [H]

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MNPPMKTRGTLYGVGLGPGDPELVTVKAARVIGQADVVAYHSARHGRSIARRIAEPYLRDGQIEEHLVYPVTTEVTDHPG
GYAGAMEDFYREAAERIAAHLDAGRDVALLAEGDPLFYSSYMHMHTRLTERFTAEIVPGVTSVSAASAAIATPLVQGEGV
LTILPGTLPADELERRLADTDAAVVLKLGRSYPAVRAALAATGRLDEAFYVERASTPDQRTLSAADVDGDDKVPYFSLAM
IPGGGRRRAVTGSVTVVGLGPGAAEWMTPQSRRELAAATDLIGYGPYLDRVGLRDGQQRHPSDNTDEPARARLACTLAEQ
GRAVAVVSSGDPGVFAMATAVLEEAKQWPGVEVRVIPAMTAAQAVASRVGAPLGHDYAVISLSDRLKPWEIIEARLTAAA
RADLVLAIYNPASKTRTWQVGAMRDLLLAHRDPGTPVVIGRDVAGQREHVKVLRLADLDPADVDMRCLLIVGSSQTQWYS
DDAGDRVFTPRYYPG

Sequences:

>Translated_495_residues
MNPPMKTRGTLYGVGLGPGDPELVTVKAARVIGQADVVAYHSARHGRSIARRIAEPYLRDGQIEEHLVYPVTTEVTDHPG
GYAGAMEDFYREAAERIAAHLDAGRDVALLAEGDPLFYSSYMHMHTRLTERFTAEIVPGVTSVSAASAAIATPLVQGEGV
LTILPGTLPADELERRLADTDAAVVLKLGRSYPAVRAALAATGRLDEAFYVERASTPDQRTLSAADVDGDDKVPYFSLAM
IPGGGRRRAVTGSVTVVGLGPGAAEWMTPQSRRELAAATDLIGYGPYLDRVGLRDGQQRHPSDNTDEPARARLACTLAEQ
GRAVAVVSSGDPGVFAMATAVLEEAKQWPGVEVRVIPAMTAAQAVASRVGAPLGHDYAVISLSDRLKPWEIIEARLTAAA
RADLVLAIYNPASKTRTWQVGAMRDLLLAHRDPGTPVVIGRDVAGQREHVKVLRLADLDPADVDMRCLLIVGSSQTQWYS
DDAGDRVFTPRYYPG
>Mature_495_residues
MNPPMKTRGTLYGVGLGPGDPELVTVKAARVIGQADVVAYHSARHGRSIARRIAEPYLRDGQIEEHLVYPVTTEVTDHPG
GYAGAMEDFYREAAERIAAHLDAGRDVALLAEGDPLFYSSYMHMHTRLTERFTAEIVPGVTSVSAASAAIATPLVQGEGV
LTILPGTLPADELERRLADTDAAVVLKLGRSYPAVRAALAATGRLDEAFYVERASTPDQRTLSAADVDGDDKVPYFSLAM
IPGGGRRRAVTGSVTVVGLGPGAAEWMTPQSRRELAAATDLIGYGPYLDRVGLRDGQQRHPSDNTDEPARARLACTLAEQ
GRAVAVVSSGDPGVFAMATAVLEEAKQWPGVEVRVIPAMTAAQAVASRVGAPLGHDYAVISLSDRLKPWEIIEARLTAAA
RADLVLAIYNPASKTRTWQVGAMRDLLLAHRDPGTPVVIGRDVAGQREHVKVLRLADLDPADVDMRCLLIVGSSQTQWYS
DDAGDRVFTPRYYPG

Specific function: Methylates precorrin-2 at the C-20 position to produce precorrin-3A [H]

COG id: COG1010

COG function: function code H; Precorrin-3B methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR006364
- InterPro:   IPR006363
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.130; =2.1.1.131 [H]

Molecular weight: Translated: 53044; Mature: 53044

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPMKTRGTLYGVGLGPGDPELVTVKAARVIGQADVVAYHSARHGRSIARRIAEPYLRD
CCCCCCCCCCEEEECCCCCCCCEEEEEHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCC
GQIEEHLVYPVTTEVTDHPGGYAGAMEDFYREAAERIAAHLDAGRDVALLAEGDPLFYSS
CCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEHHH
YMHMHTRLTERFTAEIVPGVTSVSAASAAIATPLVQGEGVLTILPGTLPADELERRLADT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHCC
DAAVVLKLGRSYPAVRAALAATGRLDEAFYVERASTPDQRTLSAADVDGDDKVPYFSLAM
CCEEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCCCCHHEEEECCCCCCCCCCEEEEEE
IPGGGRRRAVTGSVTVVGLGPGAAEWMTPQSRRELAAATDLIGYGPYLDRVGLRDGQQRH
ECCCCCCEEEECCEEEEEECCCCHHHCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCC
PSDNTDEPARARLACTLAEQGRAVAVVSSGDPGVFAMATAVLEEAKQWPGVEVRVIPAMT
CCCCCCCCHHHEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCHH
AAQAVASRVGAPLGHDYAVISLSDRLKPWEIIEARLTAAARADLVLAIYNPASKTRTWQV
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEC
GAMRDLLLAHRDPGTPVVIGRDVAGQREHVKVLRLADLDPADVDMRCLLIVGSSQTQWYS
HHHHHHHHHCCCCCCCEEEECCCCCCCHHEEEEEEECCCCCCCCEEEEEEECCCCCCEEC
DDAGDRVFTPRYYPG
CCCCCEEECCCCCCC
>Mature Secondary Structure
MNPPMKTRGTLYGVGLGPGDPELVTVKAARVIGQADVVAYHSARHGRSIARRIAEPYLRD
CCCCCCCCCCEEEECCCCCCCCEEEEEHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCC
GQIEEHLVYPVTTEVTDHPGGYAGAMEDFYREAAERIAAHLDAGRDVALLAEGDPLFYSS
CCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEHHH
YMHMHTRLTERFTAEIVPGVTSVSAASAAIATPLVQGEGVLTILPGTLPADELERRLADT
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHCC
DAAVVLKLGRSYPAVRAALAATGRLDEAFYVERASTPDQRTLSAADVDGDDKVPYFSLAM
CCEEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCCCCHHEEEECCCCCCCCCCEEEEEE
IPGGGRRRAVTGSVTVVGLGPGAAEWMTPQSRRELAAATDLIGYGPYLDRVGLRDGQQRH
ECCCCCCEEEECCEEEEEECCCCHHHCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCC
PSDNTDEPARARLACTLAEQGRAVAVVSSGDPGVFAMATAVLEEAKQWPGVEVRVIPAMT
CCCCCCCCHHHEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCHH
AAQAVASRVGAPLGHDYAVISLSDRLKPWEIIEARLTAAARADLVLAIYNPASKTRTWQV
HHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCEEEEC
GAMRDLLLAHRDPGTPVVIGRDVAGQREHVKVLRLADLDPADVDMRCLLIVGSSQTQWYS
HHHHHHHHHCCCCCCCEEEECCCCCCCHHEEEEEEECCCCCCCCEEEEEEECCCCCCEEC
DDAGDRVFTPRYYPG
CCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]