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The map label for this gene is qor [H]

Identifier: 119868507

GI number: 119868507

Start: 2594842

End: 2595816

Strand: Reverse

Name: qor [H]

Synonym: Mkms_2472

Alternate gene names: 119868507

Gene position: 2595816-2594842 (Counterclockwise)

Preceding gene: 119868509

Following gene: 119868506

Centisome position: 45.25

GC content: 70.26

Gene sequence:

>975_bases
ATGTACGCGATCGAAGTCTCCGAAACCGGCGGTCCCGAAGTCCTCACCCACGTCGAGAAGGAACCCCCTTCACCCGGCCC
GGGCCAGGTGCTGATCAAGGCCGAGGCGATCGGCGTCAACTTCATCGACACCTACTTCCGGTCGGGCCTGTATCCGCGGG
AGGTGCCGTTCGTCGTCGGCACCGAGGTCTGCGGCACGATCGAGGCCGTCGGCGACGACGTGGCGGCGCTTCAGGTGGGC
GACCGGGTGGTGACCGACAAGGCCGTCGGCGCCTATGCCGAATACACCGTGGCGCCTGCGGATTTCGTGGCCTACGTGCC
CGACGGGGTGGCCCCCGCGGTCGCCGCCTCCTCGCTGCTCAAGGGAATGACCGCCCACTACCTGATCAAGTCCACGTACC
CGGTCCAGCAGGGCGACACGGTGCTGCTGCACGCCGGGGCCGGCGGCGTCGGGCTGATCCTCACGCAGTGGGCGACGAGC
CTGACGGCCAAGGTCATCACGACCGTCTCCACACCGCAGAAGGCCGAACTCTCGCGCCAGGCCGGGGCGATCGAGGTGCT
CGACTACCCGCACGACCCGCAGGAGTTCGGCGCCCGCATCCGCGATCTCACCGGCGGCAACGGGGTGGCCGCCGTCTACG
ACGGCGTGGGCGCGGCGACTTTCGACGCCAGCCTGGCCAGCCTCGCGGTGCGCGGCACCCTCGTCCTGTTCGGCGGCGCC
AGCGGCCCGGTCCCCCCGGTCGACCCGCAGCGGCTCAACTCGGCGGGGTCGGTGTACCTGACCAGGCCCAGCCTGGTGCA
CTACACCCGCACCCCCGACGAATTCTCTTGGCGGGCAGGCGAAGTGCTCGACGCGATCGCCAAGGGGGCCATCACGGTGA
CGGTCAGCGAGCACTATCCGCTGCAGGAGGCCGAACGCGCGCACCGCGATCTGCAGGGGCGCAAGACGGTCGGTTCCGTG
GTCCTGGTCCCGTGA

Upstream 100 bases:

>100_bases
CGGGAAGGGCAGGGCAGCCGGCCAGCACGATCCGCGGATGGAACAGGTCGGGACGCGCGAGCCTCACCTGGGTCATGCTA
GGCGGTGGATGATGGTTCCC

Downstream 100 bases:

>100_bases
GGTGGCGCAGGATCTTGTGGTCTCGACGACGCTGGTGATCGCCGGATCCGAACTGAGCGAACGCTTCTCGAGGTCCTCGG
GTCCCGGCGGGCAGGGCGTC

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVGTEVCGTIEAVGDDVAALQVG
DRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAASSLLKGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQWATS
LTAKVITTVSTPQKAELSRQAGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLFGGA
SGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSEHYPLQEAERAHRDLQGRKTVGSV
VLVP

Sequences:

>Translated_324_residues
MYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVGTEVCGTIEAVGDDVAALQVG
DRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAASSLLKGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQWATS
LTAKVITTVSTPQKAELSRQAGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLFGGA
SGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSEHYPLQEAERAHRDLQGRKTVGSV
VLVP
>Mature_324_residues
MYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVGTEVCGTIEAVGDDVAALQVG
DRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAASSLLKGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQWATS
LTAKVITTVSTPQKAELSRQAGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLFGGA
SGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSEHYPLQEAERAHRDLQGRKTVGSV
VLVP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=328, Percent_Identity=30.7926829268293, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI13236495, Length=328, Percent_Identity=30.7926829268293, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=28.6585365853659, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=27.2727272727273, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=27.2727272727273, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI24308257, Length=347, Percent_Identity=25.6484149855908, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI28557745, Length=228, Percent_Identity=32.4561403508772, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=26.1980830670927, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1790485, Length=325, Percent_Identity=44.6153846153846, Blast_Score=260, Evalue=1e-70,
Organism=Escherichia coli, GI1787863, Length=212, Percent_Identity=26.8867924528302, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=240, Percent_Identity=29.5833333333333, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=34.8765432098765, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6323961, Length=267, Percent_Identity=25.4681647940075, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=251, Percent_Identity=25.4980079681275, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45550423, Length=318, Percent_Identity=26.7295597484277, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 33866; Mature: 33866

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVG
CEEEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCEEEC
TEVCGTIEAVGDDVAALQVGDRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAASSLL
CHHHHHHHHHCCCEEEEEECCEEEEHHHHCCHHHEEECCHHHEEECCCCCHHHHHHHHHH
KGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQWATSLTAKVITTVSTPQKAELSRQ
HHHHHHEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
AGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLFGGA
CCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEEEECC
SGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSEHYP
CCCCCCCCHHHCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCC
LQEAERAHRDLQGRKTVGSVVLVP
HHHHHHHHHHCCCCCCCCCEEEEC
>Mature Secondary Structure
MYAIEVSETGGPEVLTHVEKEPPSPGPGQVLIKAEAIGVNFIDTYFRSGLYPREVPFVVG
CEEEEECCCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCEEEC
TEVCGTIEAVGDDVAALQVGDRVVTDKAVGAYAEYTVAPADFVAYVPDGVAPAVAASSLL
CHHHHHHHHHCCCEEEEEECCEEEEHHHHCCHHHEEECCHHHEEECCCCCHHHHHHHHHH
KGMTAHYLIKSTYPVQQGDTVLLHAGAGGVGLILTQWATSLTAKVITTVSTPQKAELSRQ
HHHHHHEEEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHEEECCCCCHHHHHHH
AGAIEVLDYPHDPQEFGARIRDLTGGNGVAAVYDGVGAATFDASLASLAVRGTLVLFGGA
CCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHEEEEEEEEEECC
SGPVPPVDPQRLNSAGSVYLTRPSLVHYTRTPDEFSWRAGEVLDAIAKGAITVTVSEHYP
CCCCCCCCHHHCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHHHHHCCEEEEEECCCCC
LQEAERAHRDLQGRKTVGSVVLVP
HHHHHHHHHHCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]