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The map label for this gene is livM [C]

Identifier: 119868372

GI number: 119868372

Start: 2448182

End: 2449285

Strand: Reverse

Name: livM [C]

Synonym: Mkms_2336

Alternate gene names: 119868372

Gene position: 2449285-2448182 (Counterclockwise)

Preceding gene: 119868373

Following gene: 119868371

Centisome position: 42.69

GC content: 68.48

Gene sequence:

>1104_bases
ATGAGGACCTTCGTGGGACGCTGGCAGACGTGGGCGGGGTTCGGCGTGGCGGCGCTGCTGCTCTTCGCGGTGGCGCCCGC
GGTCCTGTCCGACTTCCGGCTCGGCCTGCTCGGCAAATTCCTCTGCTTCGCGATCGTCGCGGTCGGCATCGGCCTGGCCT
GGGGCCGGGGCGGCATGCTGGTCCTGGGGCAGGGGGTGTTCTTCGGCCTCGGCGGCTACATGATGGGCATGCACCTCAAG
ATCTCCGATGCGCAGCTGCGCGGAGACGATGTGCCGGACTTCATGCAGATCGCCGGTGTGCGCGAATTGCCCGGCTACTG
GGCGCCGTTCGCCTCCCCCGCCTTCACGCTGCTGGCGATCGTCGTGATCCCGACCGGCATTGCCGCGGTGCTGGGTTTCG
GGGTGTTCAAGCGCCGGGTCAAGGGCGCCTACTTCGCGATCCTGTCCCAGGCGCTGGCGGCCGCGCTGGCCATCCTGCTG
GTCGGCCAGACCGGGCTGGGGGGAAGCAACGGGCTGACGAACTTCCGGACGTTCTTCGGGTTCGCGCTCAACGATCCGGT
CAACAAGCAGATGCTCTACTTCATCGCCGCGGCGGTGCTGCTGGTCGTGGTCGCGGTGGTGCGGCAACTGATGCAGAGCC
GCTACGGCGAACTGCTCGTGGCAGTGCGCGACGGTGAGGAGCGGGTGCGCTTCCTCGGCTACGACCCGGCCAACATCAAG
GTCGTCGCCTACACGGTGGCCGCGCTGTGCGCCAGCATCGCCGGAGCGCTGTTCGCCCCGATCGTCGGATTCATGGCGCC
GTCTCAGGTGGGCATCCTGCCGTCCATCGCCTTCCTCATCGGCGTCGCGATCGGTGGCCGCACCACCCTGCTCGGACCGG
TGCTCGGCGCCATCGGCGTCGCGTGGGCGCAGACCCTGTTCTCCGAACGGTTCCCGTCGGAGTGGATCTACGCCCAGGGC
CTGCTGTTCATCGTCGTCGTCGGGTTCTTCCCCGCCGGGCTGGCCGGGCTCGGTGTGCTGCTCAAACGACGGCGTAGGAA
GAAGTCGGAACCCGTACCCGCACAACCCGATCCGCAACCCGAGAAGGTGGGGGCGCCCACATGA

Upstream 100 bases:

>100_bases
CCACCGCGTCGCTGGCCAAGGTGATCGTCTTCGTGATCATCGTGATCTTCCTGCAGGCGCGCCCGCAGGGCCTGTTCACC
GTTCGGACAAGGAGTCTCGT

Downstream 100 bases:

>100_bases
CGACCACCACCGACCGCGAACCGGTCGCCGGCGGCAACGCCGGCATGGGGGCGGAGTACCTCGAAGTCCGCGGGCTGACC
GTCGATTTCGACGGGTTCAA

Product: inner-membrane translocator

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: Inner-Membrane Translocator; Branched-Chain Amino Acid ABC Transporter Permease Protein; ABC Transporter Permease Protein; Urea ABC Transporter Permease UrtC; ABC Transporter ; Amino Acid Or Sugar ABC Transport System Permease Protein; Branched-Chain Amino Acid ABC Transporter Permease; Branched Chain Amino Acid ABC Transporter Permease; Branched-Chain Amino Acid Transport System Permease Protein; ABC Transporter; Permease Of ABC Transporter; Branched-Chain Amino Acid Transport Permease; ABC Transporter Permease; ABC Transporter Membrane Spanning Protein; Urea Or Short-Chain Amide ABC Transporter; Urea ABC Transporter Permease; Urea Transport System Permease Protein; Urea Or Short-Chain Amide ABC Transporter Permease Protein; ABC Transporter Inner-Membrane Translocator; Amide-Urea Transport System Permease Protein; ABC-Type Transport System Permease Protein; Branched Chain Amino Acid ABC Transporter Permease Protein; Amide-Urea Transporter Permease Protein; Integral Membrane Protein; Urea ABC Transporter Inner-Membrane Subunit UrtC; Transmembrane Component Of ABC Transporter; High-Affinity Branched-Chain Amino Acid Transport System; Urea/Short Chain-Amide ABC Transporter Permease Protein; ABC Branched Amino Acid Transporter Permease Component; Urea ABC Transporter Permease Protein; ABC Transporter Related Protein; Branched-Chain Amino Acid Transport System Permease; ABC Transporter Membrane Protein; Permease Protein Of ABC Transporter; Branched-Chain Amino Acid Transporter; Urea Transport System Permease Component Protein; ABC-Type Urea Transport System Permease Protein II; Permease Component Of ABC Transporter; Permease Transporter Transmembrane Protein; Urea ABC Transport Permease Component UrtC

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MRTFVGRWQTWAGFGVAALLLFAVAPAVLSDFRLGLLGKFLCFAIVAVGIGLAWGRGGMLVLGQGVFFGLGGYMMGMHLK
ISDAQLRGDDVPDFMQIAGVRELPGYWAPFASPAFTLLAIVVIPTGIAAVLGFGVFKRRVKGAYFAILSQALAAALAILL
VGQTGLGGSNGLTNFRTFFGFALNDPVNKQMLYFIAAAVLLVVVAVVRQLMQSRYGELLVAVRDGEERVRFLGYDPANIK
VVAYTVAALCASIAGALFAPIVGFMAPSQVGILPSIAFLIGVAIGGRTTLLGPVLGAIGVAWAQTLFSERFPSEWIYAQG
LLFIVVVGFFPAGLAGLGVLLKRRRRKKSEPVPAQPDPQPEKVGAPT

Sequences:

>Translated_367_residues
MRTFVGRWQTWAGFGVAALLLFAVAPAVLSDFRLGLLGKFLCFAIVAVGIGLAWGRGGMLVLGQGVFFGLGGYMMGMHLK
ISDAQLRGDDVPDFMQIAGVRELPGYWAPFASPAFTLLAIVVIPTGIAAVLGFGVFKRRVKGAYFAILSQALAAALAILL
VGQTGLGGSNGLTNFRTFFGFALNDPVNKQMLYFIAAAVLLVVVAVVRQLMQSRYGELLVAVRDGEERVRFLGYDPANIK
VVAYTVAALCASIAGALFAPIVGFMAPSQVGILPSIAFLIGVAIGGRTTLLGPVLGAIGVAWAQTLFSERFPSEWIYAQG
LLFIVVVGFFPAGLAGLGVLLKRRRRKKSEPVPAQPDPQPEKVGAPT
>Mature_367_residues
MRTFVGRWQTWAGFGVAALLLFAVAPAVLSDFRLGLLGKFLCFAIVAVGIGLAWGRGGMLVLGQGVFFGLGGYMMGMHLK
ISDAQLRGDDVPDFMQIAGVRELPGYWAPFASPAFTLLAIVVIPTGIAAVLGFGVFKRRVKGAYFAILSQALAAALAILL
VGQTGLGGSNGLTNFRTFFGFALNDPVNKQMLYFIAAAVLLVVVAVVRQLMQSRYGELLVAVRDGEERVRFLGYDPANIK
VVAYTVAALCASIAGALFAPIVGFMAPSQVGILPSIAFLIGVAIGGRTTLLGPVLGAIGVAWAQTLFSERFPSEWIYAQG
LLFIVVVGFFPAGLAGLGVLLKRRRRKKSEPVPAQPDPQPEKVGAPT

Specific function: Part Of The Binding-Protein-Dependent Transport System For Branched-Chain Amino Acids. Probably Responsible For The Translocation Of The Substrates Across The Membrane. [C]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789865, Length=319, Percent_Identity=25.705329153605, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 38837; Mature: 38837

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTFVGRWQTWAGFGVAALLLFAVAPAVLSDFRLGLLGKFLCFAIVAVGIGLAWGRGGML
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VLGQGVFFGLGGYMMGMHLKISDAQLRGDDVPDFMQIAGVRELPGYWAPFASPAFTLLAI
EEECHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHCCHHHCCCCCCCCCCHHHHHHHH
VVIPTGIAAVLGFGVFKRRVKGAYFAILSQALAAALAILLVGQTGLGGSNGLTNFRTFFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FALNDPVNKQMLYFIAAAVLLVVVAVVRQLMQSRYGELLVAVRDGEERVRFLGYDPANIK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHEECCCCCCHH
VVAYTVAALCASIAGALFAPIVGFMAPSQVGILPSIAFLIGVAIGGRTTLLGPVLGAIGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AWAQTLFSERFPSEWIYAQGLLFIVVVGFFPAGLAGLGVLLKRRRRKKSEPVPAQPDPQP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EKVGAPT
CCCCCCC
>Mature Secondary Structure
MRTFVGRWQTWAGFGVAALLLFAVAPAVLSDFRLGLLGKFLCFAIVAVGIGLAWGRGGML
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
VLGQGVFFGLGGYMMGMHLKISDAQLRGDDVPDFMQIAGVRELPGYWAPFASPAFTLLAI
EEECHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHCCHHHCCCCCCCCCCHHHHHHHH
VVIPTGIAAVLGFGVFKRRVKGAYFAILSQALAAALAILLVGQTGLGGSNGLTNFRTFFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
FALNDPVNKQMLYFIAAAVLLVVVAVVRQLMQSRYGELLVAVRDGEERVRFLGYDPANIK
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCHHHHHEECCCCCCHH
VVAYTVAALCASIAGALFAPIVGFMAPSQVGILPSIAFLIGVAIGGRTTLLGPVLGAIGV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AWAQTLFSERFPSEWIYAQGLLFIVVVGFFPAGLAGLGVLLKRRRRKKSEPVPAQPDPQP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EKVGAPT
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA