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The map label for this gene is trkA [H]

Identifier: 119868278

GI number: 119868278

Start: 2352159

End: 2352827

Strand: Reverse

Name: trkA [H]

Synonym: Mkms_2242

Alternate gene names: 119868278

Gene position: 2352827-2352159 (Counterclockwise)

Preceding gene: 119868279

Following gene: 119868275

Centisome position: 41.01

GC content: 67.12

Gene sequence:

>669_bases
GTGAAGGTAGCTATCGCCGGGGCCGGCGCCGTGGGCCGGTCCATCGCCAGGGAACTCCTCGAAAGCAACCACGAGGTGAC
GCTGCTCGAACGCAACCCCGACCACATCGACGTCGACGCGATACCCGCCGCGCACTGGCGGCTCGGCGACGCCTGTGAGA
TCTCCGTGCTCGAGTCGGTCCACCTCGAGGATTTCGACGTGGTGATCGGCGCCACCGGCGACGACAAGGTCAACGTGGTG
GTGAGCCTGCTGGCCAAGACCGAATTCGGGGTCTCGCGGGTGGTCGCGCGGGTCAACGACCCGCGCAACGAGTGGTTGTT
CGACGAGAACTGGGGCGTCGACGTCGCGGTGTCGACCCCCCGGATGCTGGCCTCTCTGGTCGAGGAGGCGGTCGCCGTTG
GTGATCTGGTGCGGCTCATGGAGTTTCGCAAGGGGCAGGCCAACCTCGTGGAGATCACCCTGCCCGACGACACGCCGTGG
GGCGGTAAAGCGGTCAAACGCCTCGAACTGCCCCGGGATTCGGCGCTCGTCACGATCCTTCGCGGTCCGCGGGTCATCGT
CCCCGAGGGCGACGAGCCACTCGAAGGCGGCGACGAATTGTTGTTCGTCGCGTCGGCGGAGGTCGAGGACGAGCTCAGCC
GCCTGCTGCTCAATCCCAAGCAGCGCTGA

Upstream 100 bases:

>100_bases
GATCAGGTCTACATCGCCGCCGTGGCAGGCCATATCGCGGAGGCGATGGCGATCAGCGCGCTGCCCCCGGGTGAGGACGA
CTCGTGAAGGTGGCCGTTTC

Downstream 100 bases:

>100_bases
GGATCAGTCCGTCGCGGCAAGCGCGGCGTGGAGGGCACGCTGGGCGCTGCGGATGGCGAAGTAGGTGACCAGGGCCGCGA
CGGCGGTCAACGGCCAGCCC

Product: TrkA domain-containing protein

Products: NA

Alternate protein names: K(+)-uptake protein trkA [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKVAIAGAGAVGRSIARELLESNHEVTLLERNPDHIDVDAIPAAHWRLGDACEISVLESVHLEDFDVVIGATGDDKVNVV
VSLLAKTEFGVSRVVARVNDPRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPW
GGKAVKRLELPRDSALVTILRGPRVIVPEGDEPLEGGDELLFVASAEVEDELSRLLLNPKQR

Sequences:

>Translated_222_residues
MKVAIAGAGAVGRSIARELLESNHEVTLLERNPDHIDVDAIPAAHWRLGDACEISVLESVHLEDFDVVIGATGDDKVNVV
VSLLAKTEFGVSRVVARVNDPRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPW
GGKAVKRLELPRDSALVTILRGPRVIVPEGDEPLEGGDELLFVASAEVEDELSRLLLNPKQR
>Mature_222_residues
MKVAIAGAGAVGRSIARELLESNHEVTLLERNPDHIDVDAIPAAHWRLGDACEISVLESVHLEDFDVVIGATGDDKVNVV
VSLLAKTEFGVSRVVARVNDPRNEWLFDENWGVDVAVSTPRMLASLVEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPW
GGKAVKRLELPRDSALVTILRGPRVIVPEGDEPLEGGDELLFVASAEVEDELSRLLLNPKQR

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=238, Percent_Identity=26.890756302521, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 24209; Mature: 24209

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAIAGAGAVGRSIARELLESNHEVTLLERNPDHIDVDAIPAAHWRLGDACEISVLESV
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEEHHHC
HLEDFDVVIGATGDDKVNVVVSLLAKTEFGVSRVVARVNDPRNEWLFDENWGVDVAVSTP
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHCCEECCCCCEEEEECCH
RMLASLVEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPWGGKAVKRLELPRDSALVTIL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHEECCCCCCEEEEEE
RGPRVIVPEGDEPLEGGDELLFVASAEVEDELSRLLLNPKQR
CCCEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKVAIAGAGAVGRSIARELLESNHEVTLLERNPDHIDVDAIPAAHWRLGDACEISVLESV
CEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEEHHHC
HLEDFDVVIGATGDDKVNVVVSLLAKTEFGVSRVVARVNDPRNEWLFDENWGVDVAVSTP
CCCCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCHHCCEECCCCCEEEEECCH
RMLASLVEEAVAVGDLVRLMEFRKGQANLVEITLPDDTPWGGKAVKRLELPRDSALVTIL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHEECCCCCCEEEEEE
RGPRVIVPEGDEPLEGGDELLFVASAEVEDELSRLLLNPKQR
CCCEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 9784509 [H]