| Definition | Mycobacterium sp. KMS chromosome, complete genome. |
|---|---|
| Accession | NC_008705 |
| Length | 5,737,227 |
Click here to switch to the map view.
The map label for this gene is hypF [H]
Identifier: 119868218
GI number: 119868218
Start: 2298567
End: 2300825
Strand: Reverse
Name: hypF [H]
Synonym: Mkms_2182
Alternate gene names: 119868218
Gene position: 2300825-2298567 (Counterclockwise)
Preceding gene: 119868219
Following gene: 119868217
Centisome position: 40.1
GC content: 72.6
Gene sequence:
>2259_bases ATGCGGTTGTGTGTGCGCGGCGTGGTCCAGGGGGTCGGCTTCCGGCCCTTCGTGTACACCACCGCGACGGCGCTCGGACT GACCGGGTCGGTGCGCAACGACAGCGCGGGCGCGGTCGTCGAGATCGAGGGCGACCCGGACGCGCTGACCCGCTTCGTCG AGCGGTTGCACACCCGGCCGCCACCGCTCGCGGTCATCGAATCCGTTGACATCGAAGACCTTCCGCCCGTCGGCGGCACC GGGTTCTTCATCGCCGACACCTCTCGCGGCCGCGGCCGCACGCTGGCCTCACCGGATGTCGCGATGTGCGCGCAGTGCGC CGCCGAACAGCGCGACCCCGGCGACCGGCGCTACCGGCACCCGTTCGTCAACTGCACCGACTGCGGACCCCGGTTCACCA TCATCGCGTCGCTGCCCTACGACCGGGCCGCCACGTCGATGGCCGGTTTCGCGATGTGCGCGGACTGCGCCCGCGAGTAC GCCGACCCCACCGACCGCCGCTTCCACGCGCAACCCGTGTGCTGCCCGCACTGCGGCCCGACCCTGACCTTCCGCGACGC CGACGGACGCCACACTGCGGGCGAGGACGGTCTGCGCCGGGCGCGGCGGCTGCTCCGCGACGGGGGTGTCGTCGCGGTGA AGGGCATCGGCGGCTACCACCTGGCCTGCGATGCCGAGAACAACACCGCCGTGGCCGAACTACGCCGCCGGAAACAGCGC GGCGACAAGCCCTTCGCGGTCATGGTGCCCGATGCGGCCGCGGCCGGCCGGATCGCCGTGCTCGACGAGGTGGCACAGCA CCTGCTGGGCGGGCCGCAGCGGCCGATCGTGCTGGCGCCGCGACGGACACCGACCACGGTGGCGGCCGCGGTGGCGCCCG GGAACCCGGACCTGGGCGTGCTGCTGGCCTATTCGCCGCTGCACACGCTGCTGTTCGGGCTGCCCGGTGACGAACCGGGC CCCCAGGTGCTGGTGATGACGTCGGGGAACCTCGCGGGCGAACCCCTCTGCTACGACGACGACGACGCCGTCACCCGGCT TCGCGCACTGGCCGACGGCTGGCTGATGCACGACCGCGAGATCCTGGTGCCCTGTGACGATTCGGTGGTCCGGGTGGTCG ACGGCGTCGAACTGCCGATCCGGCGCTCCCGGGGGTACGCCCCGTTGCCGGTGGCCCTGCCCCTCGCGGTACCGCCGACA CTCGCGGTCGGTGCGGACCTGAAGAACACCATGGCTGTCGCCGACGGCCGATACGCCTGGCTGAGCCAGCACATCGGCGA CATGGACGACATCGCGACACTGTCGGCGTTCACCGCCGCGGAACGGCATCTGCGCGAACTCACCGGCGTGGCCCCGCAGA TCCTCGCGACCGACGCCCACCCGCGGTACCGCTCGACCGGATGGGCCCAGCGACACGCCGGTGACCGGCCGGTGCGGGCG GTACAGCACCACCACGCCCACATCGCCGCGGTGATGGCCGAGCACGGGCTCGACGGTTCGGCGCCCGTACTCGGATTCGC CTTCGACGGAACCGGATACGGGCCCGACGGCGCGGTGTGGGGCGGGGAGGTCCTGCTCGCCGACTACAAGGGCTTCCGCA GGATCGCGGCGCTGGAGTACGTGCCACTGGCCGGCGGCGATGTCAGCGTCCTGCGGCCGTACCGGATGGCGCTCGCACAT CTGTGGGCCGCCGGGTTGCCGTGGGCCGGCGACCTGCCGCCGGTGCAGGCGTGTCCGGAAGACGAGCGGCGGGTGCTGCG CCACCAACTGGAGACCGGCCTGAACTGTGTGCCCACCTCCAGCATGGGGCGGTTGTTCGACTGCGTCGCCGCGCTCGCGG GGGTCCGGCAGACCGTCGCCTACGAGGCGCAGGCGGCGATCGAGCTCGAGGCGCTGGCGCGCACCGTCGACGACGATCCC GCGCCCTACGCCTTCACCGTCACCGAGTCCTCGGGGACGGCGATGATCGGCGCCGCCGCGGTGGTCGAGGCGATCGTCGC CGACCGCAGGCGCGGCACGGCGGCCGCGGTGATCGGATGGCGATTCCACCATGCGGTGGCCGACCTCGTCGTACGGTTGG CCGAGGGAGCCCGCGACCCCGTGGCGCTGTCGGGCGGGGTGTTCCAAAACGCCCTGCTCCTGCGCATGACGTTGCGCGCG TTGACCGAACGCGGTGTCGAGGTGCTGACCCACCGCCGGGTGCCGCCGAACGACGGCGGCATCGCACTGGGTCAGTTGAT GGTGGCCAACGCAGGGTGA
Upstream 100 bases:
>100_bases AGACCGACCGGGCGGGGGCCGACGCGGCGATGGCCGGACTCGAACTCATGGGCCGCGGCGGACCGCCGGACCCGGAGGCC GCACCGTGACCCGCCGTCGG
Downstream 100 bases:
>100_bases GGCCGGAGTAGAGGAGGACGCGGATGTGTTTGGCGGTACCGGGAAAGATCGACAGCGTCACCGACCGTGACGGCACGCTG ATGGCCGTCGTCGACTTCGG
Product: (NiFe) hydrogenase maturation protein HypF
Products: NA
Alternate protein names: Carbamoyl phosphate-converting enzyme hypF; [NiFe]-hydrogenase maturation factor hypF; Hydrogenase maturation protein hypF [H]
Number of amino acids: Translated: 752; Mature: 752
Protein sequence:
>752_residues MRLCVRGVVQGVGFRPFVYTTATALGLTGSVRNDSAGAVVEIEGDPDALTRFVERLHTRPPPLAVIESVDIEDLPPVGGT GFFIADTSRGRGRTLASPDVAMCAQCAAEQRDPGDRRYRHPFVNCTDCGPRFTIIASLPYDRAATSMAGFAMCADCAREY ADPTDRRFHAQPVCCPHCGPTLTFRDADGRHTAGEDGLRRARRLLRDGGVVAVKGIGGYHLACDAENNTAVAELRRRKQR GDKPFAVMVPDAAAAGRIAVLDEVAQHLLGGPQRPIVLAPRRTPTTVAAAVAPGNPDLGVLLAYSPLHTLLFGLPGDEPG PQVLVMTSGNLAGEPLCYDDDDAVTRLRALADGWLMHDREILVPCDDSVVRVVDGVELPIRRSRGYAPLPVALPLAVPPT LAVGADLKNTMAVADGRYAWLSQHIGDMDDIATLSAFTAAERHLRELTGVAPQILATDAHPRYRSTGWAQRHAGDRPVRA VQHHHAHIAAVMAEHGLDGSAPVLGFAFDGTGYGPDGAVWGGEVLLADYKGFRRIAALEYVPLAGGDVSVLRPYRMALAH LWAAGLPWAGDLPPVQACPEDERRVLRHQLETGLNCVPTSSMGRLFDCVAALAGVRQTVAYEAQAAIELEALARTVDDDP APYAFTVTESSGTAMIGAAAVVEAIVADRRRGTAAAVIGWRFHHAVADLVVRLAEGARDPVALSGGVFQNALLLRMTLRA LTERGVEVLTHRRVPPNDGGIALGQLMVANAG
Sequences:
>Translated_752_residues MRLCVRGVVQGVGFRPFVYTTATALGLTGSVRNDSAGAVVEIEGDPDALTRFVERLHTRPPPLAVIESVDIEDLPPVGGT GFFIADTSRGRGRTLASPDVAMCAQCAAEQRDPGDRRYRHPFVNCTDCGPRFTIIASLPYDRAATSMAGFAMCADCAREY ADPTDRRFHAQPVCCPHCGPTLTFRDADGRHTAGEDGLRRARRLLRDGGVVAVKGIGGYHLACDAENNTAVAELRRRKQR GDKPFAVMVPDAAAAGRIAVLDEVAQHLLGGPQRPIVLAPRRTPTTVAAAVAPGNPDLGVLLAYSPLHTLLFGLPGDEPG PQVLVMTSGNLAGEPLCYDDDDAVTRLRALADGWLMHDREILVPCDDSVVRVVDGVELPIRRSRGYAPLPVALPLAVPPT LAVGADLKNTMAVADGRYAWLSQHIGDMDDIATLSAFTAAERHLRELTGVAPQILATDAHPRYRSTGWAQRHAGDRPVRA VQHHHAHIAAVMAEHGLDGSAPVLGFAFDGTGYGPDGAVWGGEVLLADYKGFRRIAALEYVPLAGGDVSVLRPYRMALAH LWAAGLPWAGDLPPVQACPEDERRVLRHQLETGLNCVPTSSMGRLFDCVAALAGVRQTVAYEAQAAIELEALARTVDDDP APYAFTVTESSGTAMIGAAAVVEAIVADRRRGTAAAVIGWRFHHAVADLVVRLAEGARDPVALSGGVFQNALLLRMTLRA LTERGVEVLTHRRVPPNDGGIALGQLMVANAG >Mature_752_residues MRLCVRGVVQGVGFRPFVYTTATALGLTGSVRNDSAGAVVEIEGDPDALTRFVERLHTRPPPLAVIESVDIEDLPPVGGT GFFIADTSRGRGRTLASPDVAMCAQCAAEQRDPGDRRYRHPFVNCTDCGPRFTIIASLPYDRAATSMAGFAMCADCAREY ADPTDRRFHAQPVCCPHCGPTLTFRDADGRHTAGEDGLRRARRLLRDGGVVAVKGIGGYHLACDAENNTAVAELRRRKQR GDKPFAVMVPDAAAAGRIAVLDEVAQHLLGGPQRPIVLAPRRTPTTVAAAVAPGNPDLGVLLAYSPLHTLLFGLPGDEPG PQVLVMTSGNLAGEPLCYDDDDAVTRLRALADGWLMHDREILVPCDDSVVRVVDGVELPIRRSRGYAPLPVALPLAVPPT LAVGADLKNTMAVADGRYAWLSQHIGDMDDIATLSAFTAAERHLRELTGVAPQILATDAHPRYRSTGWAQRHAGDRPVRA VQHHHAHIAAVMAEHGLDGSAPVLGFAFDGTGYGPDGAVWGGEVLLADYKGFRRIAALEYVPLAGGDVSVLRPYRMALAH LWAAGLPWAGDLPPVQACPEDERRVLRHQLETGLNCVPTSSMGRLFDCVAALAGVRQTVAYEAQAAIELEALARTVDDDP APYAFTVTESSGTAMIGAAAVVEAIVADRRRGTAAAVIGWRFHHAVADLVVRLAEGARDPVALSGGVFQNALLLRMTLRA LTERGVEVLTHRRVPPNDGGIALGQLMVANAG
Specific function: Along with hypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carb
COG id: COG0068
COG function: function code O; Hydrogenase maturation factor
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 YrdC-like domain [H]
Homologues:
Organism=Escherichia coli, GI2367152, Length=768, Percent_Identity=40.4947916666667, Blast_Score=429, Evalue=1e-121,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001792 - InterPro: IPR017968 - InterPro: IPR004421 - InterPro: IPR017945 - InterPro: IPR006070 - InterPro: IPR011125 [H]
Pfam domain/function: PF00708 Acylphosphatase; PF01300 Sua5_yciO_yrdC; PF07503 zf-HYPF [H]
EC number: NA
Molecular weight: Translated: 80069; Mature: 80069
Theoretical pI: Translated: 6.54; Mature: 6.54
Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS00150 ACYLPHOSPHATASE_1 ; PS51160 ACYLPHOSPHATASE_3 ; PS51163 YRDC
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.1 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 4.1 %Cys+Met (Translated Protein) 2.1 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 4.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLCVRGVVQGVGFRPFVYTTATALGLTGSVRNDSAGAVVEIEGDPDALTRFVERLHTRP CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCC PPLAVIESVDIEDLPPVGGTGFFIADTSRGRGRTLASPDVAMCAQCAAEQRDPGDRRYRH CCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCC PFVNCTDCGPRFTIIASLPYDRAATSMAGFAMCADCAREYADPTDRRFHAQPVCCPHCGP CCCEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC TLTFRDADGRHTAGEDGLRRARRLLRDGGVVAVKGIGGYHLACDAENNTAVAELRRRKQR EEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHC GDKPFAVMVPDAAAAGRIAVLDEVAQHLLGGPQRPIVLAPRRTPTTVAAAVAPGNPDLGV CCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCCCCEEE LLAYSPLHTLLFGLPGDEPGPQVLVMTSGNLAGEPLCYDDDDAVTRLRALADGWLMHDRE EEEECHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCE ILVPCDDSVVRVVDGVELPIRRSRGYAPLPVALPLAVPPTLAVGADLKNTMAVADGRYAW EEEECCCCHHHHHCCCCCCHHHCCCCCCCCEEECCCCCCCCEECCCCCHHEEECCCCHHH LSQHIGDMDDIATLSAFTAAERHLRELTGVAPQILATDAHPRYRSTGWAQRHAGDRPVRA HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHCCCCCCHHH VQHHHAHIAAVMAEHGLDGSAPVLGFAFDGTGYGPDGAVWGGEVLLADYKGFRRIAALEY HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHHHHEE VPLAGGDVSVLRPYRMALAHLWAAGLPWAGDLPPVQACPEDERRVLRHQLETGLNCVPTS EECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCH SMGRLFDCVAALAGVRQTVAYEAQAAIELEALARTVDDDPAPYAFTVTESSGTAMIGAAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEHHHHH VVEAIVADRRRGTAAAVIGWRFHHAVADLVVRLAEGARDPVALSGGVFQNALLLRMTLRA HHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHH LTERGVEVLTHRRVPPNDGGIALGQLMVANAG HHHCCHHHHHCCCCCCCCCCEEEEEEEEECCC >Mature Secondary Structure MRLCVRGVVQGVGFRPFVYTTATALGLTGSVRNDSAGAVVEIEGDPDALTRFVERLHTRP CCHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCC PPLAVIESVDIEDLPPVGGTGFFIADTSRGRGRTLASPDVAMCAQCAAEQRDPGDRRYRH CCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHCC PFVNCTDCGPRFTIIASLPYDRAATSMAGFAMCADCAREYADPTDRRFHAQPVCCPHCGP CCCEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC TLTFRDADGRHTAGEDGLRRARRLLRDGGVVAVKGIGGYHLACDAENNTAVAELRRRKQR EEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHC GDKPFAVMVPDAAAAGRIAVLDEVAQHLLGGPQRPIVLAPRRTPTTVAAAVAPGNPDLGV CCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEECCCCCCEEE LLAYSPLHTLLFGLPGDEPGPQVLVMTSGNLAGEPLCYDDDDAVTRLRALADGWLMHDRE EEEECHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEECCCE ILVPCDDSVVRVVDGVELPIRRSRGYAPLPVALPLAVPPTLAVGADLKNTMAVADGRYAW EEEECCCCHHHHHCCCCCCHHHCCCCCCCCEEECCCCCCCCEECCCCCHHEEECCCCHHH LSQHIGDMDDIATLSAFTAAERHLRELTGVAPQILATDAHPRYRSTGWAQRHAGDRPVRA HHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHCCCCCCHHH VQHHHAHIAAVMAEHGLDGSAPVLGFAFDGTGYGPDGAVWGGEVLLADYKGFRRIAALEY HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEECHHHHHHHHHHEE VPLAGGDVSVLRPYRMALAHLWAAGLPWAGDLPPVQACPEDERRVLRHQLETGLNCVPTS EECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCH SMGRLFDCVAALAGVRQTVAYEAQAAIELEALARTVDDDPAPYAFTVTESSGTAMIGAAA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEHHHHH VVEAIVADRRRGTAAAVIGWRFHHAVADLVVRLAEGARDPVALSGGVFQNALLLRMTLRA HHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHH LTERGVEVLTHRRVPPNDGGIALGQLMVANAG HHHCCHHHHHCCCCCCCCCCEEEEEEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8590279; 8905231 [H]