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The map label for this gene is ideR [H]

Identifier: 119868179

GI number: 119868179

Start: 2265274

End: 2265996

Strand: Reverse

Name: ideR [H]

Synonym: Mkms_2143

Alternate gene names: 119868179

Gene position: 2265996-2265274 (Counterclockwise)

Preceding gene: 119868186

Following gene: 119868174

Centisome position: 39.5

GC content: 68.6

Gene sequence:

>723_bases
GTGACTGTGAGTCCTGACAGCAACTCCCGCGATCTGACGACGGTCGCTCAGGACTACCTCAAGACCATCTGGACCGCGCA
GGAGTGGTCGCACGAAAAAGTCAGCACGAAGTTGCTGGCCGAACGAATCGGCGTGTCGGCGTCCACCGCGTCGGAGTCGA
TCCGCAAACTCGCCGACCAGGGTCTGGTCAACCACGAGAAATACGGCGCGGTGACGCTGACCGATGCGGGCAGGCATGCG
GCCCTGCAGATGGTGCGACGGCACCGGCTGATGGAGACGTTCCTGGTCAACGAGCTGGGTTACAGCTGGGACGAGGTCCA
CGACGAGGCCGAGGTCCTCGAGCACGCGGTGTCGGATCTGATGCTGACGCGCATCGACGCCAAACTGGGCCACCCGACCC
GCGATCCGCACGGCGATCCGATACCGGCCGCCGACGGGCGGGTGCCCACCCCGCCCGCGCGCCAGCTGTCGGAGTGCGAG
GACGGCGACGCGGGCACGGTCGCCCGGATCTCCGACGCCGACCCGGAGATGCTGCGGTACTTCGACAGCGTCGGGATCAG
CCTGGACTCACGACTGCGGGTGCTGGCCCGGCGCGACTTCGCCGGACTGATCACGGTCGCCGTAGACAGCCCCGAGAGCG
CCGACGGCGGCGCCACCGACACCGAGACCACCGTCGATCTGGGCAGCCCCGCCGCCGAGGCGATCTGGGTCGTCGCGGGC
TAG

Upstream 100 bases:

>100_bases
CGTCCTGACCCCGCCAGCGCTGCACGACCGCAAGCCTACGGCGCGCCACACTCACCGGCTCCGGTAGATCACCGGATCGG
CCGCCGAATGCCTAAACTTT

Downstream 100 bases:

>100_bases
TCGCGAGAACCCGGCGCGAAAGACGCGGTCAGCGAGGCAGATCCGCGTCGGCGGCGTACACCCCGAGCAGGTCGCGGGCC
GACACGATGCCGACCAACCT

Product: iron dependent repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MTVSPDSNSRDLTTVAQDYLKTIWTAQEWSHEKVSTKLLAERIGVSASTASESIRKLADQGLVNHEKYGAVTLTDAGRHA
ALQMVRRHRLMETFLVNELGYSWDEVHDEAEVLEHAVSDLMLTRIDAKLGHPTRDPHGDPIPAADGRVPTPPARQLSECE
DGDAGTVARISDADPEMLRYFDSVGISLDSRLRVLARRDFAGLITVAVDSPESADGGATDTETTVDLGSPAAEAIWVVAG

Sequences:

>Translated_240_residues
MTVSPDSNSRDLTTVAQDYLKTIWTAQEWSHEKVSTKLLAERIGVSASTASESIRKLADQGLVNHEKYGAVTLTDAGRHA
ALQMVRRHRLMETFLVNELGYSWDEVHDEAEVLEHAVSDLMLTRIDAKLGHPTRDPHGDPIPAADGRVPTPPARQLSECE
DGDAGTVARISDADPEMLRYFDSVGISLDSRLRVLARRDFAGLITVAVDSPESADGGATDTETTVDLGSPAAEAIWVVAG
>Mature_239_residues
TVSPDSNSRDLTTVAQDYLKTIWTAQEWSHEKVSTKLLAERIGVSASTASESIRKLADQGLVNHEKYGAVTLTDAGRHAA
LQMVRRHRLMETFLVNELGYSWDEVHDEAEVLEHAVSDLMLTRIDAKLGHPTRDPHGDPIPAADGRVPTPPARQLSECED
GDAGTVARISDADPEMLRYFDSVGISLDSRLRVLARRDFAGLITVAVDSPESADGGATDTETTVDLGSPAAEAIWVVAG

Specific function: Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism [H]

COG id: COG1321

COG function: function code K; Mn-dependent transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH dtxR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR001367
- InterPro:   IPR022689
- InterPro:   IPR022687
- InterPro:   IPR008988
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02742 Fe_dep_repr_C; PF01325 Fe_dep_repress; PF04023 FeoA [H]

EC number: NA

Molecular weight: Translated: 26000; Mature: 25869

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50944 HTH_DTXR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSPDSNSRDLTTVAQDYLKTIWTAQEWSHEKVSTKLLAERIGVSASTASESIRKLADQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GLVNHEKYGAVTLTDAGRHAALQMVRRHRLMETFLVNELGYSWDEVHDEAEVLEHAVSDL
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHH
MLTRIDAKLGHPTRDPHGDPIPAADGRVPTPPARQLSECEDGDAGTVARISDADPEMLRY
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCHHHHHH
FDSVGISLDSRLRVLARRDFAGLITVAVDSPESADGGATDTETTVDLGSPAAEAIWVVAG
HHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCHHHEEEEEEC
>Mature Secondary Structure 
TVSPDSNSRDLTTVAQDYLKTIWTAQEWSHEKVSTKLLAERIGVSASTASESIRKLADQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GLVNHEKYGAVTLTDAGRHAALQMVRRHRLMETFLVNELGYSWDEVHDEAEVLEHAVSDL
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHH
MLTRIDAKLGHPTRDPHGDPIPAADGRVPTPPARQLSECEDGDAGTVARISDADPEMLRY
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCEEEECCCCHHHHHH
FDSVGISLDSRLRVLARRDFAGLITVAVDSPESADGGATDTETTVDLGSPAAEAIWVVAG
HHHHCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCCEEECCCCHHHEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]