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The map label for this gene is fadE12 [H]

Identifier: 119867828

GI number: 119867828

Start: 1897128

End: 1898270

Strand: Reverse

Name: fadE12 [H]

Synonym: Mkms_1789

Alternate gene names: 119867828

Gene position: 1898270-1897128 (Counterclockwise)

Preceding gene: 119867829

Following gene: 119867825

Centisome position: 33.09

GC content: 69.29

Gene sequence:

>1143_bases
ATGGACTTCTCGCTCACCAAAGAACAAGAACTGCTGCGCGACGGGTTGACGAAGTTCCTGTCCACCCGGTACGAACTCGA
AAAGAGCCGGGCCGCAGCCAGAACCGGCGCGGGATGGCAGCCGGACATCTGGCGTGGCTTCGCCGAGGAGCTCGGCATCC
TCGGCGCCACGCTGCCCGAGGACGCCGGCGGCATCGGCGGCGGTGCGGTCGAGGCGATGGTCATCGCCGAAGCGCTGGGC
CACGCCCTGGTGGTGGAACCGTTCGTCGACAGCGTGGTGGTGGCCGGCGGTCTGCTGCAGCGCGCCGGCGGCGAGACCGC
AAGCGCCGTCCTCGAGAAGATCGTCGAGGGCACCGCGCTGGTCGCGCTCGCCGCGACCGAGGCCACCTCGGGGGACAACT
GGCGCGATGTGTCCACCACCGCCGAGAAGGACGGCGCGGACTGGGTGCTGCGCGGCGAGAAGGTCGTGGTCACGAGCGCG
CCCCTGACCGGCCACCTGCTGGTGACGGCGCGTACGTCGGGTGGCCGGGATGACGAGGAGGGCATCTCGCTCTTCCTGGT
CGACCTCTCGGCGGTGCAGGGCGGCCTCACGATGCACGCCTACCGCACGATCGACGACCGTCGCGCCGCCGACATCACGT
TCGACGGTGTGCGGATCCCCGGCGAGGCGCTGCTCGGCGAGGAGGGTCGGGCCTGGCCGTCGATCGCCCGGGCCCGCGAC
GAAGGGGCGGCGGCCGTCTGCGCAGAGGCCGTCGGCGCGATGCGCAGGGTGCTCGCCGACACCGTCGAGTACTGCAAACA
ACGCCATCAGTTCGGCACTCCCATCGGCAGCTTCCAGGTGCTCCAACACCGGATGGTCGACATGCACATGGAGGTCGAGC
AATCCGTTGCGGCGACCTATCTGGCGGTGCTCAACCTGGAATCCGACGAAATGGTGCGTGCGCGGGCGGTGTCGGCGGCC
AAGGCCACCATCGGCCGTGCGGCGCGGTTCGTCGGCCAGAACGCCGTCCAACTGCACGGCGGTATGGGGATGACCGAGGA
GCTCGCGATCGGTCACTACTTCAAACGGCTCACCGCACTGCAGTACGAGTTCGGCTCCACCGACCACCACATCAGCCGGT
ACGCACAGCTGACGCGTCCCTGA

Upstream 100 bases:

>100_bases
TGGCGCCCCTGCGCTACTTCAACGACCGCGCCGGCTCGATCTACGCCGGCAGCAACGAAATTCAACGCAACATCCTGGCT
AAGGCAGCATTGGGGCTCTG

Downstream 100 bases:

>100_bases
CCTCGCCGGACCGGGGTGTCCGGCGAAACGTCCTGATGTGCGGCGGGCACCTCACAAAGACTGTGGCTCAACCACTTCGA
GGATGCGGTCACACCGGTCG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDFSLTKEQELLRDGLTKFLSTRYELEKSRAAARTGAGWQPDIWRGFAEELGILGATLPEDAGGIGGGAVEAMVIAEALG
HALVVEPFVDSVVVAGGLLQRAGGETASAVLEKIVEGTALVALAATEATSGDNWRDVSTTAEKDGADWVLRGEKVVVTSA
PLTGHLLVTARTSGGRDDEEGISLFLVDLSAVQGGLTMHAYRTIDDRRAADITFDGVRIPGEALLGEEGRAWPSIARARD
EGAAAVCAEAVGAMRRVLADTVEYCKQRHQFGTPIGSFQVLQHRMVDMHMEVEQSVAATYLAVLNLESDEMVRARAVSAA
KATIGRAARFVGQNAVQLHGGMGMTEELAIGHYFKRLTALQYEFGSTDHHISRYAQLTRP

Sequences:

>Translated_380_residues
MDFSLTKEQELLRDGLTKFLSTRYELEKSRAAARTGAGWQPDIWRGFAEELGILGATLPEDAGGIGGGAVEAMVIAEALG
HALVVEPFVDSVVVAGGLLQRAGGETASAVLEKIVEGTALVALAATEATSGDNWRDVSTTAEKDGADWVLRGEKVVVTSA
PLTGHLLVTARTSGGRDDEEGISLFLVDLSAVQGGLTMHAYRTIDDRRAADITFDGVRIPGEALLGEEGRAWPSIARARD
EGAAAVCAEAVGAMRRVLADTVEYCKQRHQFGTPIGSFQVLQHRMVDMHMEVEQSVAATYLAVLNLESDEMVRARAVSAA
KATIGRAARFVGQNAVQLHGGMGMTEELAIGHYFKRLTALQYEFGSTDHHISRYAQLTRP
>Mature_380_residues
MDFSLTKEQELLRDGLTKFLSTRYELEKSRAAARTGAGWQPDIWRGFAEELGILGATLPEDAGGIGGGAVEAMVIAEALG
HALVVEPFVDSVVVAGGLLQRAGGETASAVLEKIVEGTALVALAATEATSGDNWRDVSTTAEKDGADWVLRGEKVVVTSA
PLTGHLLVTARTSGGRDDEEGISLFLVDLSAVQGGLTMHAYRTIDDRRAADITFDGVRIPGEALLGEEGRAWPSIARARD
EGAAAVCAEAVGAMRRVLADTVEYCKQRHQFGTPIGSFQVLQHRMVDMHMEVEQSVAATYLAVLNLESDEMVRARAVSAA
KATIGRAARFVGQNAVQLHGGMGMTEELAIGHYFKRLTALQYEFGSTDHHISRYAQLTRP

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=358, Percent_Identity=26.2569832402235, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI4557233, Length=321, Percent_Identity=27.4143302180685, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI226958412, Length=381, Percent_Identity=24.6719160104987, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226958414, Length=339, Percent_Identity=24.7787610619469, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4557231, Length=398, Percent_Identity=25.6281407035176, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI187960098, Length=398, Percent_Identity=25.6281407035176, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI76496475, Length=339, Percent_Identity=26.5486725663717, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4557235, Length=339, Percent_Identity=26.5486725663717, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI4501859, Length=365, Percent_Identity=23.2876712328767, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI21361497, Length=351, Percent_Identity=23.6467236467236, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI7656849, Length=319, Percent_Identity=22.884012539185, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4503943, Length=338, Percent_Identity=25.7396449704142, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87081958, Length=358, Percent_Identity=24.3016759776536, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786223, Length=378, Percent_Identity=24.0740740740741, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=315, Percent_Identity=28.8888888888889, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17534899, Length=358, Percent_Identity=28.2122905027933, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=369, Percent_Identity=27.10027100271, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=25.4545454545455, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=333, Percent_Identity=27.027027027027, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17506239, Length=345, Percent_Identity=23.768115942029, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=357, Percent_Identity=25.7703081232493, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=315, Percent_Identity=24.4444444444444, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=313, Percent_Identity=25.8785942492013, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71990804, Length=268, Percent_Identity=25.3731343283582, Blast_Score=85, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=270, Percent_Identity=27.037037037037, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=236, Percent_Identity=25, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17533517, Length=322, Percent_Identity=21.7391304347826, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982178, Length=246, Percent_Identity=24.7967479674797, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24666513, Length=352, Percent_Identity=26.4204545454545, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24660351, Length=359, Percent_Identity=28.133704735376, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21355753, Length=331, Percent_Identity=26.8882175226586, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21356377, Length=320, Percent_Identity=25, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363737, Length=359, Percent_Identity=23.6768802228412, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646207, Length=313, Percent_Identity=24.6006389776358, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40634; Mature: 40634

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFSLTKEQELLRDGLTKFLSTRYELEKSRAAARTGAGWQPDIWRGFAEELGILGATLPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
DAGGIGGGAVEAMVIAEALGHALVVEPFVDSVVVAGGLLQRAGGETASAVLEKIVEGTAL
CCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEE
VALAATEATSGDNWRDVSTTAEKDGADWVLRGEKVVVTSAPLTGHLLVTARTSGGRDDEE
EEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEECCCCEEEEEEEECCCCCCCCC
GISLFLVDLSAVQGGLTMHAYRTIDDRRAADITFDGVRIPGEALLGEEGRAWPSIARARD
CCEEEEEEHHHHCCCCEEEEEECCCCCCCCCEEECCEECCCHHHCCCCCCCCHHHHHHCC
EGAAAVCAEAVGAMRRVLADTVEYCKQRHQFGTPIGSFQVLQHRMVDMHMEVEQSVAATY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLNLESDEMVRARAVSAAKATIGRAARFVGQNAVQLHGGMGMTEELAIGHYFKRLTAL
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHH
QYEFGSTDHHISRYAQLTRP
HHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDFSLTKEQELLRDGLTKFLSTRYELEKSRAAARTGAGWQPDIWRGFAEELGILGATLPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
DAGGIGGGAVEAMVIAEALGHALVVEPFVDSVVVAGGLLQRAGGETASAVLEKIVEGTAL
CCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEE
VALAATEATSGDNWRDVSTTAEKDGADWVLRGEKVVVTSAPLTGHLLVTARTSGGRDDEE
EEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCEEEEEECCCCEEEEEEEECCCCCCCCC
GISLFLVDLSAVQGGLTMHAYRTIDDRRAADITFDGVRIPGEALLGEEGRAWPSIARARD
CCEEEEEEHHHHCCCCEEEEEECCCCCCCCCEEECCEECCCHHHCCCCCCCCHHHHHHCC
EGAAAVCAEAVGAMRRVLADTVEYCKQRHQFGTPIGSFQVLQHRMVDMHMEVEQSVAATY
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LAVLNLESDEMVRARAVSAAKATIGRAARFVGQNAVQLHGGMGMTEELAIGHYFKRLTAL
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHH
QYEFGSTDHHISRYAQLTRP
HHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]