Click here to switch to the map view.

The map label for this gene is fprA [H]

Identifier: 119867677

GI number: 119867677

Start: 1747343

End: 1748719

Strand: Reverse

Name: fprA [H]

Synonym: Mkms_1632

Alternate gene names: 119867677

Gene position: 1748719-1747343 (Counterclockwise)

Preceding gene: 119867687

Following gene: 119867676

Centisome position: 30.48

GC content: 68.19

Gene sequence:

>1377_bases
ATGCCCCAGAAGCGCCCGTATCACGTGGCGATCGTCGGTTCCGGCCCGTCCGGCTACTTCGCCGCATCCTCCCTGCTGAA
ATTCGCCGACAGCGACGACGCCGACCGCGATGTCCGCGTCGACATGCTCGAGATGCTGCCGACCCCCTGGGGTCTCGTGC
GCTCGGGCGTCGCGCCCGACCATCCGAAGATCAAGTCCATCAGCGCGCAGTTCGACAAGACGTCGGGCGACCCACGCTTC
CGGTTCTTCGGCAACATCGCCGTCGGTGAGCATGTGCACCCCGAGGAGTTGGCCGAGCGCTACGACGCGGTGGTGTACGC
GGTCGGCGCGCAGTCCGACCGCGCACTGAACATTCCCGGCGAGCACCTTCCGGGCAGCGTTGCGGCCGTCGACTTCGTCG
GCTGGTACAACGCCCATCCGCACTTCGAGCAGATGGGGCCCGACCTGTCGACCGGCCGCGCGATCGTGGTGGGCAACGGC
AACGTCGCACTCGACGTCGCCCGGATCCTCGTCACCGATCCCGAGGCGCTGTCCCGCACCGACATCGCCGACCACGCACT
CGAATCGCTGCACCGGCGTGGCGTCGAGGAGGTCGTCGTCATCGGCAGGCGCGGACCCCTGCAGGCCACGTTCACCACGC
TCGAACTCCGCGAACTCGGCGACCTCGAGGGGCTCGGCGACGTCGACGTCATCGTCGACCCCGCCGATCTCGCCGACATC
ACCGATGACGAACTCGAGGCGGCAGGCAAAACCGTCAAACAGAACGTCAAGGTCCTACGCGGCTACGCCGAACGTCCACC
GCGCGGTGCCACGCGGCGGATCGTGTTCCGGTTCCGCACGTCGCCCATCGAGATCAAGGGCCGCGAGCACGTCGAGTCGA
TCGTGTTGGGACGCAACGAACTCGTCGACGACAACGGGCGGGTGGTCGCCAAGGACACCGGCGAACGGGAGGAACTGCCG
GCGCAGTTGGTGGTCCGCGCGGTGGGCTACCGCGGGGTGCCTACTCCGGGTCTGCCGTTCGACGAACGCAGCGGGACGAT
TCCGCACACCGACGGCCGCATCGACGGCCGGCGCAACGAGTACGTGGTCGGTTGGATCAAGCGTGGACCGTCCGGGGTGA
TCGGCAGCAACAAGAAGGACTCGCAGGCGACGGTCGACACGGTCGTCGGCGACCTGCGTGGCGCCTCGCTGGCCGACTTC
GGTGACGACCACTCCGACCGGCTGGTGGAGTGGCTGGTGTCCCGTCAACCCAAGCTGGTCACCGATGACCACTGGAAGTT
GATCGACGAGCACGAACGGTCGGCCGGGCAGACGGCCGGGCGGCCGCGGGTGAAGCTGACGAGCGTGGCCGAACTCCTCC
GCATCGGGCACGGCTGA

Upstream 100 bases:

>100_bases
GGCGCGAAGCCGTCGCGTTTAGAGTCGGACGGGTAACCAGTCCGGCCGCGTCGCGACAGCCCCTTGCGCGTGGTCGGGCA
GCGACAGAAGGCACCCTCAC

Downstream 100 bases:

>100_bases
GCCGGGTCACTCGCCCGGCGGTGGTGTCACGCGGTCGGCTTCGACCGTGACGATGACGCGGATCTCCGGCCTGCCGGTGA
AGTTGGGGTAGGGCGTGCCC

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MPQKRPYHVAIVGSGPSGYFAASSLLKFADSDDADRDVRVDMLEMLPTPWGLVRSGVAPDHPKIKSISAQFDKTSGDPRF
RFFGNIAVGEHVHPEELAERYDAVVYAVGAQSDRALNIPGEHLPGSVAAVDFVGWYNAHPHFEQMGPDLSTGRAIVVGNG
NVALDVARILVTDPEALSRTDIADHALESLHRRGVEEVVVIGRRGPLQATFTTLELRELGDLEGLGDVDVIVDPADLADI
TDDELEAAGKTVKQNVKVLRGYAERPPRGATRRIVFRFRTSPIEIKGREHVESIVLGRNELVDDNGRVVAKDTGEREELP
AQLVVRAVGYRGVPTPGLPFDERSGTIPHTDGRIDGRRNEYVVGWIKRGPSGVIGSNKKDSQATVDTVVGDLRGASLADF
GDDHSDRLVEWLVSRQPKLVTDDHWKLIDEHERSAGQTAGRPRVKLTSVAELLRIGHG

Sequences:

>Translated_458_residues
MPQKRPYHVAIVGSGPSGYFAASSLLKFADSDDADRDVRVDMLEMLPTPWGLVRSGVAPDHPKIKSISAQFDKTSGDPRF
RFFGNIAVGEHVHPEELAERYDAVVYAVGAQSDRALNIPGEHLPGSVAAVDFVGWYNAHPHFEQMGPDLSTGRAIVVGNG
NVALDVARILVTDPEALSRTDIADHALESLHRRGVEEVVVIGRRGPLQATFTTLELRELGDLEGLGDVDVIVDPADLADI
TDDELEAAGKTVKQNVKVLRGYAERPPRGATRRIVFRFRTSPIEIKGREHVESIVLGRNELVDDNGRVVAKDTGEREELP
AQLVVRAVGYRGVPTPGLPFDERSGTIPHTDGRIDGRRNEYVVGWIKRGPSGVIGSNKKDSQATVDTVVGDLRGASLADF
GDDHSDRLVEWLVSRQPKLVTDDHWKLIDEHERSAGQTAGRPRVKLTSVAELLRIGHG
>Mature_457_residues
PQKRPYHVAIVGSGPSGYFAASSLLKFADSDDADRDVRVDMLEMLPTPWGLVRSGVAPDHPKIKSISAQFDKTSGDPRFR
FFGNIAVGEHVHPEELAERYDAVVYAVGAQSDRALNIPGEHLPGSVAAVDFVGWYNAHPHFEQMGPDLSTGRAIVVGNGN
VALDVARILVTDPEALSRTDIADHALESLHRRGVEEVVVIGRRGPLQATFTTLELRELGDLEGLGDVDVIVDPADLADIT
DDELEAAGKTVKQNVKVLRGYAERPPRGATRRIVFRFRTSPIEIKGREHVESIVLGRNELVDDNGRVVAKDTGEREELPA
QLVVRAVGYRGVPTPGLPFDERSGTIPHTDGRIDGRRNEYVVGWIKRGPSGVIGSNKKDSQATVDTVVGDLRGASLADFG
DDHSDRLVEWLVSRQPKLVTDDHWKLIDEHERSAGQTAGRPRVKLTSVAELLRIGHG

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=469, Percent_Identity=39.6588486140725, Blast_Score=296, Evalue=4e-80,
Organism=Homo sapiens, GI111118983, Length=475, Percent_Identity=39.1578947368421, Blast_Score=290, Evalue=3e-78,
Organism=Caenorhabditis elegans, GI17543860, Length=456, Percent_Identity=31.7982456140351, Blast_Score=220, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6320584, Length=486, Percent_Identity=31.8930041152263, Blast_Score=203, Evalue=6e-53,
Organism=Drosophila melanogaster, GI17137178, Length=470, Percent_Identity=36.3829787234043, Blast_Score=267, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 49987; Mature: 49856

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKRPYHVAIVGSGPSGYFAASSLLKFADSDDADRDVRVDMLEMLPTPWGLVRSGVAPD
CCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCC
HPKIKSISAQFDKTSGDPRFRFFGNIAVGEHVHPEELAERYDAVVYAVGAQSDRALNIPG
CCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCEEEEEECCCCCCEECCCC
EHLPGSVAAVDFVGWYNAHPHFEQMGPDLSTGRAIVVGNGNVALDVARILVTDPEALSRT
CCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCCEEEEECCCEEEEEEEEEEECCHHHHHH
DIADHALESLHRRGVEEVVVIGRRGPLQATFTTLELRELGDLEGLGDVDVIVDPADLADI
HHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEHHHCCCCCCCCCCEEEECCHHHCCC
TDDELEAAGKTVKQNVKVLRGYAERPPRGATRRIVFRFRTSPIEIKGREHVESIVLGRNE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEECCHHHHHHHHHCCHH
LVDDNGRVVAKDTGEREELPAQLVVRAVGYRGVPTPGLPFDERSGTIPHTDGRIDGRRNE
EECCCCEEEECCCCCHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YVVGWIKRGPSGVIGSNKKDSQATVDTVVGDLRGASLADFGDDHSDRLVEWLVSRQPKLV
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEE
TDDHWKLIDEHERSAGQTAGRPRVKLTSVAELLRIGHG
CCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCC
>Mature Secondary Structure 
PQKRPYHVAIVGSGPSGYFAASSLLKFADSDDADRDVRVDMLEMLPTPWGLVRSGVAPD
CCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCC
HPKIKSISAQFDKTSGDPRFRFFGNIAVGEHVHPEELAERYDAVVYAVGAQSDRALNIPG
CCCHHHHHHHCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCEEEEEECCCCCCEECCCC
EHLPGSVAAVDFVGWYNAHPHFEQMGPDLSTGRAIVVGNGNVALDVARILVTDPEALSRT
CCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCCEEEEECCCEEEEEEEEEEECCHHHHHH
DIADHALESLHRRGVEEVVVIGRRGPLQATFTTLELRELGDLEGLGDVDVIVDPADLADI
HHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEEEHHHCCCCCCCCCCEEEECCHHHCCC
TDDELEAAGKTVKQNVKVLRGYAERPPRGATRRIVFRFRTSPIEIKGREHVESIVLGRNE
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCEEECCHHHHHHHHHCCHH
LVDDNGRVVAKDTGEREELPAQLVVRAVGYRGVPTPGLPFDERSGTIPHTDGRIDGRRNE
EECCCCEEEECCCCCHHHCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
YVVGWIKRGPSGVIGSNKKDSQATVDTVVGDLRGASLADFGDDHSDRLVEWLVSRQPKLV
EEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEE
TDDHWKLIDEHERSAGQTAGRPRVKLTSVAELLRIGHG
CCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]