Definition Mycobacterium sp. KMS chromosome, complete genome.
Accession NC_008705
Length 5,737,227

Click here to switch to the map view.

The map label for this gene is ykvO [H]

Identifier: 119867546

GI number: 119867546

Start: 1611862

End: 1612632

Strand: Direct

Name: ykvO [H]

Synonym: Mkms_1498

Alternate gene names: 119867546

Gene position: 1611862-1612632 (Clockwise)

Preceding gene: 119867543

Following gene: 119867547

Centisome position: 28.09

GC content: 66.02

Gene sequence:

>771_bases
ATGCGTCTCGCGAACAAGGTAACCCTCGTCACCGGCGGGAGCGCGGGCCTTGGCCTGGCGATTGCCCAGAGATTCGGCAG
TGAAGGCGCCCACGTCTATATCACGGGGCGACGGCGGGAGGCGCTCGAAGCCGCGAGGGCTTCCATCGAGGGACGTGTCA
CGGCGCTCACCGCGGACGCTACGGTCCCCGGTGATCTCGACCTTCTGATCGAGACGATCCGCCGGGAGAGCGGGCACCTC
GACGTCGTCGTCGCCAACGCCGGGAGCATCGAGCGGATGAACTTCGGGGACGTGACCGAGGAACATTTCGACCGCACCTT
CGACCTCAACGCCCGCGGCACACTGTTCACCGTCCAGAAGGCGCTGCTCACCGTCCAGAAGGCGCTGCCGCTTCTACGAA
CAGGCGGCTCGATAGTCCTGCTGGGCTCGGTCACTGCGCTCCAGGGGCACCCCGGGGCGGGGACTTACAGCGCGGCGAAG
GCTGCCGTACGCTCCTACGCGCGCACGTGGTCAGCAGAGTTCGGCGACAAGGGCCTCCGGGTCAACGTGCTGAGCCCGGG
GCCGATCGACACGCCCATCATCGACGGCCAGGCCGACTACTTCGGTCAAGACCCAGTAGCTCTCCGAGCCCAGATGAGCA
CCCTTGTCCCGATGGGCCGCCTCGGACGTCCCGAGGAGATCGCTAATGGTGCACTGTTTCTCGCCTCGGACGAGAGCAGT
TTCATGACGGGGGCAGAACTTTGCATCGACGGCGGTATGGCTCGGGTATAG

Upstream 100 bases:

>100_bases
TGGTGCCCACAGCCAGCACCAGACCCTGCGATGCCAGCTAAAAGCCCGTCAAGGCAAGGCAATTGGGTCCGTCAGCCGCA
CATCGACTCAAGGAGAAAGC

Downstream 100 bases:

>100_bases
CCCGCTTCGGCCCGATCGCATCCTGCGGGCTGGCTCGCTCAGCAGTAAAGCGGCGACCTCAGCACTGGATGTCTGTTCAT
GATGGTCCGTCAACCGGGAG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MRLANKVTLVTGGSAGLGLAIAQRFGSEGAHVYITGRRREALEAARASIEGRVTALTADATVPGDLDLLIETIRRESGHL
DVVVANAGSIERMNFGDVTEEHFDRTFDLNARGTLFTVQKALLTVQKALPLLRTGGSIVLLGSVTALQGHPGAGTYSAAK
AAVRSYARTWSAEFGDKGLRVNVLSPGPIDTPIIDGQADYFGQDPVALRAQMSTLVPMGRLGRPEEIANGALFLASDESS
FMTGAELCIDGGMARV

Sequences:

>Translated_256_residues
MRLANKVTLVTGGSAGLGLAIAQRFGSEGAHVYITGRRREALEAARASIEGRVTALTADATVPGDLDLLIETIRRESGHL
DVVVANAGSIERMNFGDVTEEHFDRTFDLNARGTLFTVQKALLTVQKALPLLRTGGSIVLLGSVTALQGHPGAGTYSAAK
AAVRSYARTWSAEFGDKGLRVNVLSPGPIDTPIIDGQADYFGQDPVALRAQMSTLVPMGRLGRPEEIANGALFLASDESS
FMTGAELCIDGGMARV
>Mature_256_residues
MRLANKVTLVTGGSAGLGLAIAQRFGSEGAHVYITGRRREALEAARASIEGRVTALTADATVPGDLDLLIETIRRESGHL
DVVVANAGSIERMNFGDVTEEHFDRTFDLNARGTLFTVQKALLTVQKALPLLRTGGSIVLLGSVTALQGHPGAGTYSAAK
AAVRSYARTWSAEFGDKGLRVNVLSPGPIDTPIIDGQADYFGQDPVALRAQMSTLVPMGRLGRPEEIANGALFLASDESS
FMTGAELCIDGGMARV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=264, Percent_Identity=31.4393939393939, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=28.2442748091603, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI40254992, Length=251, Percent_Identity=29.8804780876494, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI15277342, Length=265, Percent_Identity=29.4339622641509, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=27.3076923076923, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=31.1538461538462, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=31.25, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=35.0649350649351, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI4503301, Length=241, Percent_Identity=30.2904564315353, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=28.2868525896414, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI33667109, Length=195, Percent_Identity=29.2307692307692, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=25.968992248062, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI40807363, Length=202, Percent_Identity=26.7326732673267, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI4758504, Length=257, Percent_Identity=27.2373540856031, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503817, Length=229, Percent_Identity=27.0742358078603, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=33.59375, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787335, Length=257, Percent_Identity=34.2412451361868, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=33.7121212121212, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI2367365, Length=254, Percent_Identity=35.0393700787402, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=28.6821705426357, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1786812, Length=259, Percent_Identity=30.8880308880309, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787905, Length=255, Percent_Identity=29.4117647058824, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=29.1338582677165, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=26.8774703557312, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082160, Length=265, Percent_Identity=25.2830188679245, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787820, Length=213, Percent_Identity=25.8215962441315, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787545, Length=267, Percent_Identity=26.9662921348315, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=266, Percent_Identity=33.8345864661654, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=35.7142857142857, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17560150, Length=267, Percent_Identity=32.5842696629214, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=32.2097378277154, Blast_Score=118, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=35.7933579335793, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17555706, Length=253, Percent_Identity=30.8300395256917, Blast_Score=111, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17560220, Length=274, Percent_Identity=33.2116788321168, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17565030, Length=278, Percent_Identity=32.7338129496403, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=31.3653136531365, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=34.2307692307692, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=31.1111111111111, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17538480, Length=268, Percent_Identity=30.2238805970149, Blast_Score=104, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17531453, Length=270, Percent_Identity=32.2222222222222, Blast_Score=103, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=30.3370786516854, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17538486, Length=275, Percent_Identity=30.1818181818182, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=30.4832713754647, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=30.1158301158301, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560676, Length=265, Percent_Identity=29.0566037735849, Blast_Score=101, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=30.6273062730627, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=31.6205533596838, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI115534694, Length=257, Percent_Identity=29.5719844357977, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=27.7153558052434, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI72000259, Length=267, Percent_Identity=29.5880149812734, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561272, Length=243, Percent_Identity=30.0411522633745, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=27.5862068965517, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=30.1115241635688, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=29.2307692307692, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=265, Percent_Identity=27.5471698113208, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=257, Percent_Identity=27.2373540856031, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=200, Percent_Identity=25, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=28.2868525896414, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32563809, Length=206, Percent_Identity=30.5825242718447, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=206, Percent_Identity=30.5825242718447, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=255, Percent_Identity=26.2745098039216, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=29.6482412060301, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=29.1457286432161, Blast_Score=73, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6322861, Length=199, Percent_Identity=27.1356783919598, Blast_Score=65, Evalue=9e-12,
Organism=Drosophila melanogaster, GI23397609, Length=259, Percent_Identity=35.9073359073359, Blast_Score=133, Evalue=9e-32,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=32.5581395348837, Blast_Score=119, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=32.6848249027237, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=32.5581395348837, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=33.7254901960784, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=33.0739299610895, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=32.03125, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=29.2307692307692, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24644337, Length=257, Percent_Identity=29.5719844357977, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24641232, Length=245, Percent_Identity=26.9387755102041, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24663911, Length=212, Percent_Identity=28.7735849056604, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=23.9043824701195, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21358495, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 26954; Mature: 26954

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MRLANKVTLVTGGSAGLGLAIAQRFGSEGAHVYITGRRREALEAARASIEGRVTALTADA
CCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCEEEEEEECC
TVPGDLDLLIETIRRESGHLDVVVANAGSIERMNFGDVTEEHFDRTFDLNARGTLFTVQK
CCCCHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCHHHCCCEECCCCCCHHHHHHH
ALLTVQKALPLLRTGGSIVLLGSVTALQGHPGAGTYSAAKAAVRSYARTWSAEFGDKGLR
HHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
VNVLSPGPIDTPIIDGQADYFGQDPVALRAQMSTLVPMGRLGRPEEIANGALFLASDESS
EEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCEEEEEECCCC
FMTGAELCIDGGMARV
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MRLANKVTLVTGGSAGLGLAIAQRFGSEGAHVYITGRRREALEAARASIEGRVTALTADA
CCCCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHCCCCEEEEEEECC
TVPGDLDLLIETIRRESGHLDVVVANAGSIERMNFGDVTEEHFDRTFDLNARGTLFTVQK
CCCCHHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCCHHHCCCEECCCCCCHHHHHHH
ALLTVQKALPLLRTGGSIVLLGSVTALQGHPGAGTYSAAKAAVRSYARTWSAEFGDKGLR
HHHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCE
VNVLSPGPIDTPIIDGQADYFGQDPVALRAQMSTLVPMGRLGRPEEIANGALFLASDESS
EEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCEEEEEECCCC
FMTGAELCIDGGMARV
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]