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The map label for this gene is cadC [H]

Identifier: 119867540

GI number: 119867540

Start: 1604854

End: 1605237

Strand: Direct

Name: cadC [H]

Synonym: Mkms_1492

Alternate gene names: 119867540

Gene position: 1604854-1605237 (Clockwise)

Preceding gene: 119867534

Following gene: 119867541

Centisome position: 27.97

GC content: 67.71

Gene sequence:

>384_bases
ATGAGTGAGCCGCTGGATACCTGCGATCTGCTGTGTTTGGACCTGCCCCACGCGGAGCAGATCAGGGCCACGGTGCCAGA
TAGCGACACGGTGGCTGCCGCGGCCGCGGCCGCCCGCGGCTTGAGTGATGCCACCCGGTTGTCGATCGCCGCGGCGTTGG
CGGCCGGCGATGAACTGTGCGTGTGCGACATGGCCTGGGTGATCGGCCTCTCGCAGGGTTTGGTGTCGCATCATCTGCGC
CAGCTCAAGAACGCCTCCCTGGTGTCCTCGCGCAGGCAGGGCAAGTTGGTGATGTACCGGCTGACCGAGCGCGGACGCCA
GTTGACGGCCGCGGTGCTGCCCGCGGTGAACGTGGCCGCCCGGAAGGAGTCCGATCGTGTCTGA

Upstream 100 bases:

>100_bases
TGGCGACCGCGATGACGAAGATCGTGAGGAGCACGCGGGTGTTGGCCAGAATCGAGCTGAGGCCTTTCGTTTTCATATCA
ACGTACTTTAGTATATGGAT

Downstream 100 bases:

>100_bases
TGCGTGCTGCGGACCCGATATCGCCGCCGAACCCGAGGCGGGACCCGAAAAACTCTGGCAGGTCCGGGAATTGCAGCTCG
CCGCGCTGGCCGCGGTCCTG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 127; Mature: 126

Protein sequence:

>127_residues
MSEPLDTCDLLCLDLPHAEQIRATVPDSDTVAAAAAAARGLSDATRLSIAAALAAGDELCVCDMAWVIGLSQGLVSHHLR
QLKNASLVSSRRQGKLVMYRLTERGRQLTAAVLPAVNVAARKESDRV

Sequences:

>Translated_127_residues
MSEPLDTCDLLCLDLPHAEQIRATVPDSDTVAAAAAAARGLSDATRLSIAAALAAGDELCVCDMAWVIGLSQGLVSHHLR
QLKNASLVSSRRQGKLVMYRLTERGRQLTAAVLPAVNVAARKESDRV
>Mature_126_residues
SEPLDTCDLLCLDLPHAEQIRATVPDSDTVAAAAAAARGLSDATRLSIAAALAAGDELCVCDMAWVIGLSQGLVSHHLRQ
LKNASLVSSRRQGKLVMYRLTERGRQLTAAVLPAVNVAARKESDRV

Specific function: Metal-binding repressor for the cad operon. Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead. Metal binding causes the repressor to dissociate from the DNA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 13477; Mature: 13345

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLDTCDLLCLDLPHAEQIRATVPDSDTVAAAAAAARGLSDATRLSIAAALAAGDELC
CCCCCCCHHHHEECCCCHHHHEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCH
VCDMAWVIGLSQGLVSHHLRQLKNASLVSSRRQGKLVMYRLTERGRQLTAAVLPAVNVAA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHHHHHHH
RKESDRV
CCCCCCC
>Mature Secondary Structure 
SEPLDTCDLLCLDLPHAEQIRATVPDSDTVAAAAAAARGLSDATRLSIAAALAAGDELC
CCCCCCHHHHEECCCCHHHHEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCH
VCDMAWVIGLSQGLVSHHLRQLKNASLVSSRRQGKLVMYRLTERGRQLTAAVLPAVNVAA
HHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCEEEEEEHHCCHHHHHHHHHHHHHHH
RKESDRV
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1321115 [H]