Definition Mycobacterium sp. KMS chromosome, complete genome.
Accession NC_008705
Length 5,737,227

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The map label for this gene is ecsA [H]

Identifier: 119867528

GI number: 119867528

Start: 1590213

End: 1590815

Strand: Direct

Name: ecsA [H]

Synonym: Mkms_1478

Alternate gene names: 119867528

Gene position: 1590213-1590815 (Clockwise)

Preceding gene: 119867527

Following gene: 119867529

Centisome position: 27.72

GC content: 61.69

Gene sequence:

>603_bases
ATGTCGCACCGCCAGCAGGTTCTGCGCGGCGCCGATCTGTCGCTGATGCCGGGCGAGATCGTCGGTCTCGTCGGGGAGAA
CGGCTCGGGCAAGTCAACCATGATGAAGATCTTGGTTGGCGAGTTAGCCGCGGATGGGGGAACAGTTACTCGCTCCGGTG
TACTGGGCTACTGCCCGCAGCAGCCCGTCGTATACGAACGCCTCACATGCGATGAGCATATTGAACTGTTCGCACGCGCC
TATCGCATGACCCATGAAGCCGAAGGGCGAGCTCGGCGAGACCTGTACGACGCGTTGGGATTTGAGCGTTACGCGAGCAC
ACGCGCGGATCGGCTATCGGGCGGCACGTTGGCTAAGCTCAACCTCGCGCTGGCCATGCTGGCCGATCCGCCGGTGCTGT
TACTGGATGAGCCCTACGCCGGCTTTGATTGGGACACCTATCTGAAGTTCTGGGATCTCGTAGGCCGGCGCCGAGACGGC
GGACGGTCGGTGCTGATCATCAGCCACTTCGTCACTGACGAACACCGCTTTGATCGCATTGTCAAGCTCTGCGAGGGACG
CCTGTGCCACGGGCAATGCGACGCAGATGAGACCTGCCGATGA

Upstream 100 bases:

>100_bases
CAGGCCAGGTGTTAGGGGAGCGGGCCCGGTCGCGGCAACCTCTGCGTCGATACTCAGGGCCGAAGGCATCGAGAAGTCGT
TTCACCGGGGCGTGTGGCCG

Downstream 100 bases:

>100_bases
CAACGGCGGCCCACGAACAATGGCGGCCGACATTGCTGCTGACTCGCAGCTTCATCACCGACTATGTGCGCAACCCGGTA
AACCTGATCATGCTGATCCT

Product: ABC transporter-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSHRQQVLRGADLSLMPGEIVGLVGENGSGKSTMMKILVGELAADGGTVTRSGVLGYCPQQPVVYERLTCDEHIELFARA
YRMTHEAEGRARRDLYDALGFERYASTRADRLSGGTLAKLNLALAMLADPPVLLLDEPYAGFDWDTYLKFWDLVGRRRDG
GRSVLIISHFVTDEHRFDRIVKLCEGRLCHGQCDADETCR

Sequences:

>Translated_200_residues
MSHRQQVLRGADLSLMPGEIVGLVGENGSGKSTMMKILVGELAADGGTVTRSGVLGYCPQQPVVYERLTCDEHIELFARA
YRMTHEAEGRARRDLYDALGFERYASTRADRLSGGTLAKLNLALAMLADPPVLLLDEPYAGFDWDTYLKFWDLVGRRRDG
GRSVLIISHFVTDEHRFDRIVKLCEGRLCHGQCDADETCR
>Mature_199_residues
SHRQQVLRGADLSLMPGEIVGLVGENGSGKSTMMKILVGELAADGGTVTRSGVLGYCPQQPVVYERLTCDEHIELFARAY
RMTHEAEGRARRDLYDALGFERYASTRADRLSGGTLAKLNLALAMLADPPVLLLDEPYAGFDWDTYLKFWDLVGRRRDGG
RSVLIISHFVTDEHRFDRIVKLCEGRLCHGQCDADETCR

Specific function: Has a role in exoprotein production, sporulation and competence [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI150417984, Length=197, Percent_Identity=32.994923857868, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI45446740, Length=193, Percent_Identity=33.160621761658, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI47078218, Length=193, Percent_Identity=33.160621761658, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI27477115, Length=190, Percent_Identity=31.5789473684211, Blast_Score=101, Evalue=4e-22,
Organism=Homo sapiens, GI6005701, Length=190, Percent_Identity=31.5789473684211, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI153792144, Length=201, Percent_Identity=29.3532338308458, Blast_Score=100, Evalue=8e-22,
Organism=Homo sapiens, GI105990541, Length=165, Percent_Identity=35.1515151515151, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI116734710, Length=199, Percent_Identity=30.1507537688442, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI21536376, Length=189, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=8e-21,
Organism=Homo sapiens, GI27436953, Length=189, Percent_Identity=32.8042328042328, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI27881501, Length=165, Percent_Identity=29.6969696969697, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI30795238, Length=165, Percent_Identity=29.6969696969697, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI31657092, Length=183, Percent_Identity=34.4262295081967, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI27262624, Length=186, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI27262626, Length=186, Percent_Identity=29.0322580645161, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI46592956, Length=201, Percent_Identity=28.8557213930348, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI46592915, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI46592978, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI46592898, Length=198, Percent_Identity=29.2929292929293, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI46592964, Length=198, Percent_Identity=29.2929292929293, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI46592971, Length=198, Percent_Identity=29.2929292929293, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI9955968, Length=203, Percent_Identity=30.5418719211823, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI9955966, Length=203, Percent_Identity=30.5418719211823, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI45243524, Length=203, Percent_Identity=30.5418719211823, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI157502203, Length=151, Percent_Identity=33.112582781457, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI157502201, Length=151, Percent_Identity=33.112582781457, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI215820660, Length=183, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI20143975, Length=183, Percent_Identity=27.8688524590164, Blast_Score=68, Evalue=5e-12,
Organism=Homo sapiens, GI42741659, Length=202, Percent_Identity=26.7326732673267, Blast_Score=68, Evalue=6e-12,
Organism=Escherichia coli, GI87081782, Length=191, Percent_Identity=31.9371727748691, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788165, Length=172, Percent_Identity=33.7209302325581, Blast_Score=85, Evalue=3e-18,
Organism=Escherichia coli, GI48994943, Length=189, Percent_Identity=30.1587301587302, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1789593, Length=186, Percent_Identity=30.6451612903226, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786703, Length=205, Percent_Identity=30.7317073170732, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1789751, Length=143, Percent_Identity=37.7622377622378, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1786319, Length=208, Percent_Identity=26.4423076923077, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1787105, Length=201, Percent_Identity=26.3681592039801, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790544, Length=220, Percent_Identity=29.5454545454545, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI48995001, Length=210, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788225, Length=213, Percent_Identity=25.3521126760563, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1787029, Length=201, Percent_Identity=26.3681592039801, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787792, Length=199, Percent_Identity=28.1407035175879, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787758, Length=194, Percent_Identity=27.319587628866, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87081834, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1790190, Length=202, Percent_Identity=27.7227722772277, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1786253, Length=186, Percent_Identity=25.8064516129032, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1787112, Length=213, Percent_Identity=23.943661971831, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=204, Percent_Identity=30.3921568627451, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI115533608, Length=201, Percent_Identity=29.3532338308458, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71983523, Length=200, Percent_Identity=28.5, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71983516, Length=200, Percent_Identity=28.5, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI71983510, Length=200, Percent_Identity=28.5, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17510237, Length=205, Percent_Identity=26.8292682926829, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17538654, Length=205, Percent_Identity=24.8780487804878, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71992290, Length=200, Percent_Identity=25, Blast_Score=70, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI25146777, Length=200, Percent_Identity=25, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI193211017, Length=202, Percent_Identity=25.7425742574257, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193211015, Length=202, Percent_Identity=25.7425742574257, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71996809, Length=202, Percent_Identity=25.7425742574257, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17569081, Length=195, Percent_Identity=25.6410256410256, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17552232, Length=208, Percent_Identity=27.4038461538462, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71984940, Length=206, Percent_Identity=27.6699029126214, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6320214, Length=191, Percent_Identity=27.7486910994764, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323217, Length=203, Percent_Identity=24.6305418719212, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643674, Length=201, Percent_Identity=29.8507462686567, Blast_Score=103, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24666092, Length=192, Percent_Identity=31.25, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221512771, Length=202, Percent_Identity=29.7029702970297, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28574150, Length=195, Percent_Identity=28.7179487179487, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI116007328, Length=195, Percent_Identity=28.7179487179487, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24582014, Length=211, Percent_Identity=31.7535545023697, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24582012, Length=211, Percent_Identity=31.7535545023697, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI116007184, Length=181, Percent_Identity=32.5966850828729, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI221500365, Length=181, Percent_Identity=32.5966850828729, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI28573573, Length=195, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI28573571, Length=195, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648314, Length=202, Percent_Identity=29.7029702970297, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24650855, Length=200, Percent_Identity=30.5, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24650853, Length=200, Percent_Identity=30.5, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI85724864, Length=205, Percent_Identity=27.3170731707317, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24580555, Length=205, Percent_Identity=27.3170731707317, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI85816269, Length=205, Percent_Identity=27.3170731707317, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24580553, Length=205, Percent_Identity=27.3170731707317, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI281362751, Length=201, Percent_Identity=30.3482587064677, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI161076682, Length=205, Percent_Identity=27.3170731707317, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI161076684, Length=205, Percent_Identity=27.3170731707317, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24581617, Length=205, Percent_Identity=27.3170731707317, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24581615, Length=205, Percent_Identity=27.3170731707317, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI85725262, Length=179, Percent_Identity=29.0502793296089, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24641565, Length=207, Percent_Identity=30.4347826086957, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI62484234, Length=187, Percent_Identity=28.3422459893048, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45550390, Length=186, Percent_Identity=27.9569892473118, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24581191, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24581189, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24581193, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24581195, Length=183, Percent_Identity=27.8688524590164, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24585091, Length=188, Percent_Identity=27.6595744680851, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI45552805, Length=177, Percent_Identity=28.2485875706215, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574744, Length=180, Percent_Identity=28.3333333333333, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17647219, Length=152, Percent_Identity=29.6052631578947, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24653245, Length=210, Percent_Identity=28.0952380952381, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363262, Length=210, Percent_Identity=28.0952380952381, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574259, Length=185, Percent_Identity=29.1891891891892, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161077321, Length=198, Percent_Identity=27.7777777777778, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24585557, Length=191, Percent_Identity=26.7015706806283, Blast_Score=64, Evalue=7e-11,
Organism=Drosophila melanogaster, GI45552437, Length=191, Percent_Identity=26.7015706806283, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 22308; Mature: 22177

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MSHRQQVLRGADLSLMPGEIVGLVGENGSGKSTMMKILVGELAADGGTVTRSGVLGYCPQ
CCHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEECCCEEECCCC
QPVVYERLTCDEHIELFARAYRMTHEAEGRARRDLYDALGFERYASTRADRLSGGTLAKL
CCCHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
NLALAMLADPPVLLLDEPYAGFDWDTYLKFWDLVGRRRDGGRSVLIISHFVTDEHRFDRI
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHH
VKLCEGRLCHGQCDADETCR
HHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SHRQQVLRGADLSLMPGEIVGLVGENGSGKSTMMKILVGELAADGGTVTRSGVLGYCPQ
CHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEECCCEEECCCC
QPVVYERLTCDEHIELFARAYRMTHEAEGRARRDLYDALGFERYASTRADRLSGGTLAKL
CCCHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
NLALAMLADPPVLLLDEPYAGFDWDTYLKFWDLVGRRRDGGRSVLIISHFVTDEHRFDRI
HHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHH
VKLCEGRLCHGQCDADETCR
HHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8581172; 9579061; 9384377 [H]