Click here to switch to the map view.

The map label for this gene is ubiB [C]

Identifier: 119867479

GI number: 119867479

Start: 1532199

End: 1533536

Strand: Reverse

Name: ubiB [C]

Synonym: Mkms_1429

Alternate gene names: 119867479

Gene position: 1533536-1532199 (Counterclockwise)

Preceding gene: 119867480

Following gene: 119867476

Centisome position: 26.73

GC content: 67.86

Gene sequence:

>1338_bases
ATGGATGATGGTCTGGTGGCTGATGACATCAGACGCGGGCGTGCCGCCCGCAACGCGAAGCTGGCGAGCCTGCCGGTCGG
TATGGCCGGGCGCGCGGCGTTGGGATTCGGCAAACGGCTGACCGGAAAATCCCGCGACGAGGTCAACGCCGAATTGATGG
ACAAGGCGGCTCAGCAACTGTTCACCGTGCTCGGTGAACTCAAGGGCGGCGCGATGAAGGTCGGGCAGGCCCTGTCGGTG
ATGGAGGCCGCCATCCCCGAGCAGTACGGCAAGCCGTACCGCGAGGCGCTGACCAAACTGCAGAAAGACGCCCCGCCGCT
GCCCGCCGCCAAGGTGCACCGGGTGCTCGATGCCCAGCTGGGCACCAAGTGGCGGGATCGCTTCACCTCCTTCGACGACA
AACCGATCGCCTCGGCCAGCATCGGGCAGGTGCACAAGGCGGTGTGGGCCGACGGCCGCGACGTCGCGGTCAAGATCCAG
TACCCCGGCGCCGACGAAGCCCTGCGCGCCGACCTGAAGACCATGCAGCGCATGGTCGGCGTGCTCAAGCAGCTCTCCCC
CGGCGCCGATGTCGAGGGCGTGGTCAGCGAGCTCATCGAGCGCACCGAGATGGAGCTCGACTACCGGCTGGAAGCCGACA
ACCAGCGGGCGTTCGCGAAGGCCTACCGCGACCATCCGCACTTCGCCGTTCCCGCCGTCGTCGCCAGCGCCCCGAAGGTC
GTGATCGCGGAGTGGATCTCCGGCATCCCGATGTCGGTGATCATCCGCGAGGGCACCGCCGAGCAGCGCGACCTGATGGG
CACCCGGCTCTTCGAGCTCACCCACGACGCCCCGGCGCGGCTGGAGATGATGCACGGCGATGCGCACCCCGGCAATTTCA
TGCTGCTGCCCGACGGGCGGATGGGTGTCATCGACTTCGGTGCGGTGGCGCCGCTGCCCGGCGGCCTTCCGGTCGAGTTG
GGCCAGACGCTGCGCTACGCGTCCGCCAAGGACTACGACAACCTGCTGGCCACCATGGCGCGGGTCGGCTTCATCCAGCG
CGGCGAACAGGTTCCGGCCGAGGAGATCGACGAGATGCTGCGCCAGTACGTCGAGCCCATCGAGGTCGAGGTGTTCCACT
ACACCCGCAAGTGGCTGCAGCGGATGACCGCGGTGAACATGGACCGTTCGGTGGCCCAGATCAAGACCGCCCGCCAGATG
GACATCCCGCCGAAGCTGGCGATCCCGATGCGGGTCATCGCCTCGGTGGTGGCGATCTCGTGCCAGCTCGACGCCCACGT
CCCGGTGAAAGCCATTGCCACCGAACTGATTCCGGGCTTCCGGGAGGACGCGGCCTGA

Upstream 100 bases:

>100_bases
GGCACCCGCACCACCGTCGTGCGGCGTTGGTCCCGGCACCCGCGCTGCACCTGCTGAGCGCCGTCGCGGGCCCTTCGTTG
TCGGCCCGAGGTGCGGCGTC

Downstream 100 bases:

>100_bases
GCGGCCCGGCGGCTAGGCAGCCGCCGGGTCCCGCTCGGTCTTGCGCGGGCGTCCCCGCGGACGCTTACGCGCGACGATGG
TGCCTCGTTCGAAGATCTCG

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDDGLVADDIRRGRAARNAKLASLPVGMAGRAALGFGKRLTGKSRDEVNAELMDKAAQQLFTVLGELKGGAMKVGQALSV
MEAAIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQLGTKWRDRFTSFDDKPIASASIGQVHKAVWADGRDVAVKIQ
YPGADEALRADLKTMQRMVGVLKQLSPGADVEGVVSELIERTEMELDYRLEADNQRAFAKAYRDHPHFAVPAVVASAPKV
VIAEWISGIPMSVIIREGTAEQRDLMGTRLFELTHDAPARLEMMHGDAHPGNFMLLPDGRMGVIDFGAVAPLPGGLPVEL
GQTLRYASAKDYDNLLATMARVGFIQRGEQVPAEEIDEMLRQYVEPIEVEVFHYTRKWLQRMTAVNMDRSVAQIKTARQM
DIPPKLAIPMRVIASVVAISCQLDAHVPVKAIATELIPGFREDAA

Sequences:

>Translated_445_residues
MDDGLVADDIRRGRAARNAKLASLPVGMAGRAALGFGKRLTGKSRDEVNAELMDKAAQQLFTVLGELKGGAMKVGQALSV
MEAAIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQLGTKWRDRFTSFDDKPIASASIGQVHKAVWADGRDVAVKIQ
YPGADEALRADLKTMQRMVGVLKQLSPGADVEGVVSELIERTEMELDYRLEADNQRAFAKAYRDHPHFAVPAVVASAPKV
VIAEWISGIPMSVIIREGTAEQRDLMGTRLFELTHDAPARLEMMHGDAHPGNFMLLPDGRMGVIDFGAVAPLPGGLPVEL
GQTLRYASAKDYDNLLATMARVGFIQRGEQVPAEEIDEMLRQYVEPIEVEVFHYTRKWLQRMTAVNMDRSVAQIKTARQM
DIPPKLAIPMRVIASVVAISCQLDAHVPVKAIATELIPGFREDAA
>Mature_445_residues
MDDGLVADDIRRGRAARNAKLASLPVGMAGRAALGFGKRLTGKSRDEVNAELMDKAAQQLFTVLGELKGGAMKVGQALSV
MEAAIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQLGTKWRDRFTSFDDKPIASASIGQVHKAVWADGRDVAVKIQ
YPGADEALRADLKTMQRMVGVLKQLSPGADVEGVVSELIERTEMELDYRLEADNQRAFAKAYRDHPHFAVPAVVASAPKV
VIAEWISGIPMSVIIREGTAEQRDLMGTRLFELTHDAPARLEMMHGDAHPGNFMLLPDGRMGVIDFGAVAPLPGGLPVEL
GQTLRYASAKDYDNLLATMARVGFIQRGEQVPAEEIDEMLRQYVEPIEVEVFHYTRKWLQRMTAVNMDRSVAQIKTARQM
DIPPKLAIPMRVIASVVAISCQLDAHVPVKAIATELIPGFREDAA

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI34147522, Length=383, Percent_Identity=26.8929503916449, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI27363457, Length=261, Percent_Identity=28.735632183908, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI40254938, Length=301, Percent_Identity=28.9036544850498, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI217416386, Length=346, Percent_Identity=26.5895953757225, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI217035081, Length=237, Percent_Identity=30.379746835443, Blast_Score=90, Evalue=4e-18,
Organism=Homo sapiens, GI41393593, Length=271, Percent_Identity=26.5682656826568, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI2367309, Length=410, Percent_Identity=24.390243902439, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32565180, Length=310, Percent_Identity=30.6451612903226, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17559152, Length=310, Percent_Identity=25.4838709677419, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321319, Length=350, Percent_Identity=26.5714285714286, Blast_Score=131, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323282, Length=187, Percent_Identity=26.2032085561497, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI18859849, Length=350, Percent_Identity=28.2857142857143, Blast_Score=146, Evalue=3e-35,
Organism=Drosophila melanogaster, GI22024280, Length=324, Percent_Identity=28.3950617283951, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24662575, Length=330, Percent_Identity=26.3636363636364, Blast_Score=98, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 48758; Mature: 48758

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDGLVADDIRRGRAARNAKLASLPVGMAGRAALGFGKRLTGKSRDEVNAELMDKAAQQL
CCCCCCHHHHHHCHHHCCCCHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
FTVLGELKGGAMKVGQALSVMEAAIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GTKWRDRFTSFDDKPIASASIGQVHKAVWADGRDVAVKIQYPGADEALRADLKTMQRMVG
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VLKQLSPGADVEGVVSELIERTEMELDYRLEADNQRAFAKAYRDHPHFAVPAVVASAPKV
HHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCEEHHHHHHCCCHH
VIAEWISGIPMSVIIREGTAEQRDLMGTRLFELTHDAPARLEMMHGDAHPGNFMLLPDGR
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCEEEECCCC
MGVIDFGAVAPLPGGLPVELGQTLRYASAKDYDNLLATMARVGFIQRGEQVPAEEIDEML
CCEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RQYVEPIEVEVFHYTRKWLQRMTAVNMDRSVAQIKTARQMDIPPKLAIPMRVIASVVAIS
HHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CQLDAHVPVKAIATELIPGFREDAA
HCCCCCCCHHHHHHHHCCCCHHCCC
>Mature Secondary Structure
MDDGLVADDIRRGRAARNAKLASLPVGMAGRAALGFGKRLTGKSRDEVNAELMDKAAQQL
CCCCCCHHHHHHCHHHCCCCHHCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
FTVLGELKGGAMKVGQALSVMEAAIPEQYGKPYREALTKLQKDAPPLPAAKVHRVLDAQL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
GTKWRDRFTSFDDKPIASASIGQVHKAVWADGRDVAVKIQYPGADEALRADLKTMQRMVG
CCHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VLKQLSPGADVEGVVSELIERTEMELDYRLEADNQRAFAKAYRDHPHFAVPAVVASAPKV
HHHHCCCCCCHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCEEHHHHHHCCCHH
VIAEWISGIPMSVIIREGTAEQRDLMGTRLFELTHDAPARLEMMHGDAHPGNFMLLPDGR
HHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHEEEEECCCCCCCEEEECCCC
MGVIDFGAVAPLPGGLPVELGQTLRYASAKDYDNLLATMARVGFIQRGEQVPAEEIDEML
CCEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
RQYVEPIEVEVFHYTRKWLQRMTAVNMDRSVAQIKTARQMDIPPKLAIPMRVIASVVAIS
HHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
CQLDAHVPVKAIATELIPGFREDAA
HCCCCCCCHHHHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA