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The map label for this gene is pdtaS [H]

Identifier: 119867450

GI number: 119867450

Start: 1501440

End: 1502930

Strand: Direct

Name: pdtaS [H]

Synonym: Mkms_1400

Alternate gene names: 119867450

Gene position: 1501440-1502930 (Clockwise)

Preceding gene: 119867449

Following gene: 119867453

Centisome position: 26.17

GC content: 69.55

Gene sequence:

>1491_bases
ATGTCCACCCTCGGTGACCTGCTCGCCGAGCACACCGTGCTGCCCGGCAACGCCGTCGACCATCTGCATGCGGTGGTCGG
GGAGTGGCAGCTGCTGGCCGACCTGTCCTTCGCCGATTACCTGATGTGGGTACGCCGCGACGACGGGGTGCTGGTCTGTG
TGGCGCAGGTCAGGCCCAACACCGCCGCCACCGTCCTGTTGGCCGACGCGGTGGGGACCACTGCGATCCCCGAGACCATG
CCGTTGGTCACGGCCACCTTCGAGTCGGGCATCATCGGCCGGGAAGGTCCTGCCGCGCAGAACGACGCGCCCGGCCTGAA
CGTCGAAGCGGTGCCGGTGCGCTACCGCGAAGACGTCGTCGCGGTGCTGACCCATCAGACCGCCCTGGCGGCCCGGCGGA
CCGCGAGTCCGCTGGAGGTCGCCTATCTGGACTGCGCCGGCGATCTGCTGATCATGCTCTCCGAGGGGACCTTCCCCAAC
GTCGGTGACCTGGCCATGTCACGTTCCAGCCCGCGGGTGGGGGACGGCTTCATCCGGTTGGACGGCGCGGGCAACGTGGT
GTTCGCCAGCCCCAACGCGATCTCGGCGTATCACCGGATGGGGCTGACCGCCGACCTCGAGGGCCACAACCTGGTGGCGG
TGACGCGTCCGCTCATCTCCGACCCGTTCGAGGCGCAGGAACTGGCCAACCATGTGCGGGATTCGCTCGCCGGTGGGTCC
AGCATGCGGATGGAGGTCGATGCCGGCGGTGCGGCGGTGCTGCTGCGCACGATGCCGCTCGTGGTGCACGGCGCGGCGGT
GGGCGCGGCCGTGCTGATCCGCGACGTGACCGAGGTGAAGCGGCGCGACCGTGCGCTGCTGTCGAAGGACGCGACGATCC
GTGAGATCCATCACCGGGTCAAGAACAATCTGCAGACGGTGGCCGCGCTGCTGCGTCTGCAGGCCCGGCGCACGAACAAC
GCCGAGGGGCGCGAGGCGTTGATGGAGTCCGTGCGCCGGGTGTCGTCGATCGCCCAGGTGCACGACGCGCTGTCGATGTC
GGTGGACGAGGAGGTCAACCTCGACGAGGTCGTCGACCGCATCCTGCCGATCATGAACGACGTCGCCAGCGTCGGCCCGC
CGATCCGGATCAAGCGCGAAGGTGACCTCGGCGTGCTCGACGCCGATCGGGCGACGGCGCTGATCATGGTGATCACCGAG
GTGGTGCAGAACGCCATCGAGCACGCCTTCGATGCCAGCACCGCGCAGGGCAGCGTCACGATCCGCGCCGAGCGCTCGGC
GCGGTGGCTCGACGTGGTGGTGCACGACGACGGGCGCGGTCTACCGACCGGCTTCAGCCTGGAGAAGTCCGACCGGCTGG
GGTTGCAGATCGTGCGGACGCTGGTGTCGGCGGAGTTGGACGGATCGCTCGGGATGCATGACGTGCCCAGTGGGGGGACG
GATGTGGTGCTGCGGGTCCCGATCGGTCGCCGCGGCCGAGCCGCGCAGTAG

Upstream 100 bases:

>100_bases
ACGGTGACGAAGGTCAACGTGTCCGAGGGTGACGTCATCCAGGCCGGACACCTCATCGCGGTGATCAGCTAGCGCATTCA
GCGCCCCCCGGTAGAGCGAT

Downstream 100 bases:

>100_bases
GCGGGGGCGGCCGGGCCGCGCAGTAGGCGGGGGCGGCCGGGCCGCGCAGTAATCCGGATTCACAGAGATGGCTGCGCGGG
AATTGAATTGTGGTTCCGGA

Product: signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 496; Mature: 495

Protein sequence:

>496_residues
MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQVRPNTAATVLLADAVGTTAIPETM
PLVTATFESGIIGREGPAAQNDAPGLNVEAVPVRYREDVVAVLTHQTALAARRTASPLEVAYLDCAGDLLIMLSEGTFPN
VGDLAMSRSSPRVGDGFIRLDGAGNVVFASPNAISAYHRMGLTADLEGHNLVAVTRPLISDPFEAQELANHVRDSLAGGS
SMRMEVDAGGAAVLLRTMPLVVHGAAVGAAVLIRDVTEVKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQARRTNN
AEGREALMESVRRVSSIAQVHDALSMSVDEEVNLDEVVDRILPIMNDVASVGPPIRIKREGDLGVLDADRATALIMVITE
VVQNAIEHAFDASTAQGSVTIRAERSARWLDVVVHDDGRGLPTGFSLEKSDRLGLQIVRTLVSAELDGSLGMHDVPSGGT
DVVLRVPIGRRGRAAQ

Sequences:

>Translated_496_residues
MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQVRPNTAATVLLADAVGTTAIPETM
PLVTATFESGIIGREGPAAQNDAPGLNVEAVPVRYREDVVAVLTHQTALAARRTASPLEVAYLDCAGDLLIMLSEGTFPN
VGDLAMSRSSPRVGDGFIRLDGAGNVVFASPNAISAYHRMGLTADLEGHNLVAVTRPLISDPFEAQELANHVRDSLAGGS
SMRMEVDAGGAAVLLRTMPLVVHGAAVGAAVLIRDVTEVKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQARRTNN
AEGREALMESVRRVSSIAQVHDALSMSVDEEVNLDEVVDRILPIMNDVASVGPPIRIKREGDLGVLDADRATALIMVITE
VVQNAIEHAFDASTAQGSVTIRAERSARWLDVVVHDDGRGLPTGFSLEKSDRLGLQIVRTLVSAELDGSLGMHDVPSGGT
DVVLRVPIGRRGRAAQ
>Mature_495_residues
STLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQVRPNTAATVLLADAVGTTAIPETMP
LVTATFESGIIGREGPAAQNDAPGLNVEAVPVRYREDVVAVLTHQTALAARRTASPLEVAYLDCAGDLLIMLSEGTFPNV
GDLAMSRSSPRVGDGFIRLDGAGNVVFASPNAISAYHRMGLTADLEGHNLVAVTRPLISDPFEAQELANHVRDSLAGGSS
MRMEVDAGGAAVLLRTMPLVVHGAAVGAAVLIRDVTEVKRRDRALLSKDATIREIHHRVKNNLQTVAALLRLQARRTNNA
EGREALMESVRRVSSIAQVHDALSMSVDEEVNLDEVVDRILPIMNDVASVGPPIRIKREGDLGVLDADRATALIMVITEV
VQNAIEHAFDASTAQGSVTIRAERSARWLDVVVHDDGRGLPTGFSLEKSDRLGLQIVRTLVSAELDGSLGMHDVPSGGTD
VVLRVPIGRRGRAAQ

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG3920

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52957; Mature: 52826

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQVRPN
CCCHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHCCHHHHEEEEECCCCEEEEEEECCCC
TAATVLLADAVGTTAIPETMPLVTATFESGIIGREGPAAQNDAPGLNVEAVPVRYREDVV
CCEEEEEECCCCCCCCCCCCCCEEEEHHCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHH
AVLTHQTALAARRTASPLEVAYLDCAGDLLIMLSEGTFPNVGDLAMSRSSPRVGDGFIRL
HHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHCCCCCCCCCCEEEE
DGAGNVVFASPNAISAYHRMGLTADLEGHNLVAVTRPLISDPFEAQELANHVRDSLAGGS
CCCCCEEEECCCHHHHHHHCCCEEECCCCEEEEEECCHHCCCCCHHHHHHHHHHHHCCCC
SMRMEVDAGGAAVLLRTMPLVVHGAAVGAAVLIRDVTEVKRRDRALLSKDATIREIHHRV
CEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KNNLQTVAALLRLQARRTNNAEGREALMESVRRVSSIAQVHDALSMSVDEEVNLDEVVDR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ILPIMNDVASVGPPIRIKREGDLGVLDADRATALIMVITEVVQNAIEHAFDASTAQGSVT
HHHHHHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IRAERSARWLDVVVHDDGRGLPTGFSLEKSDRLGLQIVRTLVSAELDGSLGMHDVPSGGT
EEECCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DVVLRVPIGRRGRAAQ
CEEEECCCCCCCCCCC
>Mature Secondary Structure 
STLGDLLAEHTVLPGNAVDHLHAVVGEWQLLADLSFADYLMWVRRDDGVLVCVAQVRPN
CCHHHHHHHCCCCCCCHHHHHHHHHHCHHHHHHCCHHHHEEEEECCCCEEEEEEECCCC
TAATVLLADAVGTTAIPETMPLVTATFESGIIGREGPAAQNDAPGLNVEAVPVRYREDVV
CCEEEEEECCCCCCCCCCCCCCEEEEHHCCCCCCCCCCCCCCCCCCCEEEECCHHHHHHH
AVLTHQTALAARRTASPLEVAYLDCAGDLLIMLSEGTFPNVGDLAMSRSSPRVGDGFIRL
HHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCHHHHCCCCCCCCCCEEEE
DGAGNVVFASPNAISAYHRMGLTADLEGHNLVAVTRPLISDPFEAQELANHVRDSLAGGS
CCCCCEEEECCCHHHHHHHCCCEEECCCCEEEEEECCHHCCCCCHHHHHHHHHHHHCCCC
SMRMEVDAGGAAVLLRTMPLVVHGAAVGAAVLIRDVTEVKRRDRALLSKDATIREIHHRV
CEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
KNNLQTVAALLRLQARRTNNAEGREALMESVRRVSSIAQVHDALSMSVDEEVNLDEVVDR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
ILPIMNDVASVGPPIRIKREGDLGVLDADRATALIMVITEVVQNAIEHAFDASTAQGSVT
HHHHHHHHHHCCCCEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
IRAERSARWLDVVVHDDGRGLPTGFSLEKSDRLGLQIVRTLVSAELDGSLGMHDVPSGGT
EEECCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DVVLRVPIGRRGRAAQ
CEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]