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The map label for this gene is scoA [H]

Identifier: 119867436

GI number: 119867436

Start: 1487205

End: 1487996

Strand: Direct

Name: scoA [H]

Synonym: Mkms_1386

Alternate gene names: 119867436

Gene position: 1487205-1487996 (Clockwise)

Preceding gene: 119867435

Following gene: 119867437

Centisome position: 25.92

GC content: 69.82

Gene sequence:

>792_bases
GTGACAATCGACAAAGTCGTCGGTTCGGCCCGTGATGCGGTCGCCGACATCCCGGCGGGCGCGAGCCTGGCCGTCGGTGG
GTTCGGCCTCGCCGGTATCCCGTGGTTCCTCATCGAAGCGCTGCTCGACCAGGGCGCCGACGATCTGACCATCGTCTCCA
ACAACTGCGGGGTGGACGGCGCCGGACTCGGTCTGCTCCTCGAAGCGGGCCGGATCAGCCGAGTGATCGCCTCGTACGTC
GGGGAGAACAAGGAATTCGGCAGGCAGTACCTCGCCGGCGAGTTGACCGTCGAACTCACCCCGCAAGGCACGCTCGCCGA
ACGGCTGCGCGCGGGTGGCAGCGGCCTCGGCGCGTTCTTCACTCCGACCGGTGTCGGCACGCTGGTCGCCGAGGGTGGTC
TGCCGTGGCGCTACCACCCCGACGGCAGTGTCGCGCTCGCGTCACCCCCCAAGGAGGTTCGCAGTTTCGCCGGCCGCGAC
ATGGTGCTCGAGGAAGCGATCGTCACCGACTACGCGCTGATCCGCGCCGCCGTCGTCGACCGGGCAGGCAACTGCCGGTT
CCACGCCGCGGCCCGCAACTTCAACCCGCCGGCGGCGATGGCCGGCCGGGTCACCCTCGTCGAGGCGGAAGAGGTCGTCG
AGGTGGGCGAACTGGCTCCCGACGAGATCCACCTGCCCGGCATCTTCGTCCAGCGCATCGTGGCGCTCACCCCGATCCAG
GCGCTGCGCAAGGACATCGAGAAGCGCACCACCCGGCCCCGTCCGGACGCGACACAGGAGGCGACGCGATGA

Upstream 100 bases:

>100_bases
AGGACGGCCGACTGCTGGTCGTCCCCGACGCCGCGCACCTCGCCAACGCGCAGCAACCCGGGATCGTCACCCCCGCCCTC
ATCGAACACCTGGAGCAATC

Downstream 100 bases:

>100_bases
GCTGGACCCGGGATGAGATGGCCGCGCGCGCCGCGGCCGAACTACGCGACGGCGACTACGTCAATCTCGGAATCGGTTTG
CCCACTTTGATTCCCGATCA

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTIDKVVGSARDAVADIPAGASLAVGGFGLAGIPWFLIEALLDQGADDLTIVSNNCGVDGAGLGLLLEAGRISRVIASYV
GENKEFGRQYLAGELTVELTPQGTLAERLRAGGSGLGAFFTPTGVGTLVAEGGLPWRYHPDGSVALASPPKEVRSFAGRD
MVLEEAIVTDYALIRAAVVDRAGNCRFHAAARNFNPPAAMAGRVTLVEAEEVVEVGELAPDEIHLPGIFVQRIVALTPIQ
ALRKDIEKRTTRPRPDATQEATR

Sequences:

>Translated_263_residues
MTIDKVVGSARDAVADIPAGASLAVGGFGLAGIPWFLIEALLDQGADDLTIVSNNCGVDGAGLGLLLEAGRISRVIASYV
GENKEFGRQYLAGELTVELTPQGTLAERLRAGGSGLGAFFTPTGVGTLVAEGGLPWRYHPDGSVALASPPKEVRSFAGRD
MVLEEAIVTDYALIRAAVVDRAGNCRFHAAARNFNPPAAMAGRVTLVEAEEVVEVGELAPDEIHLPGIFVQRIVALTPIQ
ALRKDIEKRTTRPRPDATQEATR
>Mature_262_residues
TIDKVVGSARDAVADIPAGASLAVGGFGLAGIPWFLIEALLDQGADDLTIVSNNCGVDGAGLGLLLEAGRISRVIASYVG
ENKEFGRQYLAGELTVELTPQGTLAERLRAGGSGLGAFFTPTGVGTLVAEGGLPWRYHPDGSVALASPPKEVRSFAGRDM
VLEEAIVTDYALIRAAVVDRAGNCRFHAAARNFNPPAAMAGRVTLVEAEEVVEVGELAPDEIHLPGIFVQRIVALTPIQA
LRKDIEKRTTRPRPDATQEATR

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=252, Percent_Identity=55.952380952381, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI11545841, Length=245, Percent_Identity=54.2857142857143, Blast_Score=236, Evalue=2e-62,
Organism=Escherichia coli, GI1788551, Length=235, Percent_Identity=42.5531914893617, Blast_Score=178, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17531517, Length=251, Percent_Identity=52.5896414342629, Blast_Score=253, Evalue=6e-68,
Organism=Drosophila melanogaster, GI21358325, Length=251, Percent_Identity=51.792828685259, Blast_Score=261, Evalue=4e-70,
Organism=Drosophila melanogaster, GI24655794, Length=251, Percent_Identity=51.792828685259, Blast_Score=261, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 27666; Mature: 27535

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDKVVGSARDAVADIPAGASLAVGGFGLAGIPWFLIEALLDQGADDLTIVSNNCGVDG
CCHHHHHCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
AGLGLLLEAGRISRVIASYVGENKEFGRQYLAGELTVELTPQGTLAERLRAGGSGLGAFF
CCHHHEEHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCCEE
TPTGVGTLVAEGGLPWRYHPDGSVALASPPKEVRSFAGRDMVLEEAIVTDYALIRAAVVD
CCCCCHHHEECCCCCEEECCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RAGNCRFHAAARNFNPPAAMAGRVTLVEAEEVVEVGELAPDEIHLPGIFVQRIVALTPIQ
CCCCCEEEEECCCCCCCHHHHCCEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCHHH
ALRKDIEKRTTRPRPDATQEATR
HHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIDKVVGSARDAVADIPAGASLAVGGFGLAGIPWFLIEALLDQGADDLTIVSNNCGVDG
CHHHHHCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
AGLGLLLEAGRISRVIASYVGENKEFGRQYLAGELTVELTPQGTLAERLRAGGSGLGAFF
CCHHHEEHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCCEE
TPTGVGTLVAEGGLPWRYHPDGSVALASPPKEVRSFAGRDMVLEEAIVTDYALIRAAVVD
CCCCCHHHEECCCCCEEECCCCCEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RAGNCRFHAAARNFNPPAAMAGRVTLVEAEEVVEVGELAPDEIHLPGIFVQRIVALTPIQ
CCCCCEEEEECCCCCCCHHHHCCEEEEEHHHHHHHHCCCCCCCCCCHHHHHHHHHHCHHH
ALRKDIEKRTTRPRPDATQEATR
HHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]