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The map label for this gene is manB [H]

Identifier: 119867395

GI number: 119867395

Start: 1438510

End: 1439907

Strand: Direct

Name: manB [H]

Synonym: Mkms_1345

Alternate gene names: 119867395

Gene position: 1438510-1439907 (Clockwise)

Preceding gene: 119867394

Following gene: 119867396

Centisome position: 25.07

GC content: 69.81

Gene sequence:

>1398_bases
ATGTCTCGGCCGGCTGCGGCGGTGCATCGCGTCATCAAGGCGTATGACGTTCGTGGCCTGGTAGGTGAGGAACTCGACGA
GGGGTTCGTCGCCGACGTCGGCGCGGCGTTCGCACGGCTGGTCGCCGACGGCGCGACCCAGATCGTGATCGGCCACGACA
TGCGGTCGAGTTCACCGGCGCTGTCGGAGGCATTCGCCGAGGGCGCGATGGCCCAGGGCCTCGACGTGGTGCGGATCGGG
TTGGCCTCCACCGATCAGCTGTACTTCGCCTCGGGGTTGCTGGACTGCCCCGGCGCGATGTTCACCGCCAGCCACAACCC
GGCCGCCTACAACGGCATCAAGCTGTGCCGCGCCGGGGCCAAACCGGTCGGCCGGGACACCGGGCTGGCGCAGATCGCCG
AGCAGGTCATCGACGGCGTCCCCGCCCACGACGGACCGCGCGGCAGCGCGTCGGACCGCGACGTGCTGACCGACTACGGC
GCGTTCCTGCGGTCGCTGGTGGAGATCCCCGGGCGGCGTCCCCTGCGCGTCGCCGTCGACGCGGGCAACGGGATGGCGGG
CCACACGACGCCGGCGGTCCTCGGCCCCATCGAGGCGATCACCCTGCTGCCGCTGTTCTTCGAACTCGACGGCACCTTCC
CCAACCACGAGGCCAACCCGCTGGATCCGGCCAACCTGATCGATCTGCAGGCGCACGTCGTCGCCGTCGGCGCCGATATC
GGTCTGGCCTTCGACGGTGACGCCGACCGTTGCTTCGTCGTCGACGAGAAGGGGCAGGCGGTGTCGCCGTCGGCGGTCAC
CGCGCTGGTGGCCGCGCGCGAACTCGGCCGCGAGATCGGTGCGACGGTGATCCACAACCTGATCACCTCGAGGGCGGTTC
CCGAACTCGTCGCCGAACGCGGCGGAACGGCGGTCCGCTCACGCGTCGGGCACTCCTACATCAAGGCGCTGATGGCCGAG
ACGGGCGCGATCTTCGGCGGCGAACACTCGGCGCACTACTACTTCCGGGACTTCTGGGGTGCGGACTCGGGCATGCTGGC
CGCGCTGCACGTGCTGGCCGCGCTCAGCGAACAGGACCGCCCGCTGTCGGATTTCATGGCCGACTACCAGCGCTACGAGG
CGTCGGGCGAGATCAACTTCACCGTCGCCGACGCGCCCGCCTGTGTGGAGGCGGTGCTCAAGTCTTTCGGTACCCGCATC
CACTCCATCGACCACCTCGACGGGGTGACCGTCGACCTCGGCGGCGGTCAGTGGTTCAACCTGCGCACCTCCAACACCGA
ACCGTTGCTGCGCCTCAACGTCGAAGCGCGGACCGCCGAGGAGGTCGACGAGGTGGTCGGGCAGGTCTCCGAGACCGTGC
GGGCCCAGAACGCCGAACCGGGCAGGACATCGACGTGA

Upstream 100 bases:

>100_bases
CGCGTGCTGCCCGACCCCGCCGAGTAGGGCGTCATAGCCACGCGAACGATCCCTCCGGTGCGGATAGGCTGACGGAAAGT
CCCCGACTCCAAGGAGTTGT

Downstream 100 bases:

>100_bases
CCGGATCATCGGCTGCCGTGGTGGACCTCGACGACGGAGAGGCCCTGCTGGCCGCCGACCGCGACGGTCTGCTGAGGGCG
GCCGCGATGGCCGGTGCGCA

Product: phosphomannomutase/phosphoglucomutase

Products: NA

Alternate protein names: Phosphoglucomutase; PGM; Glucose phosphomutase; Phosphomannomutase; PMM [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSRPAAAVHRVIKAYDVRGLVGEELDEGFVADVGAAFARLVADGATQIVIGHDMRSSSPALSEAFAEGAMAQGLDVVRIG
LASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGAKPVGRDTGLAQIAEQVIDGVPAHDGPRGSASDRDVLTDYG
AFLRSLVEIPGRRPLRVAVDAGNGMAGHTTPAVLGPIEAITLLPLFFELDGTFPNHEANPLDPANLIDLQAHVVAVGADI
GLAFDGDADRCFVVDEKGQAVSPSAVTALVAARELGREIGATVIHNLITSRAVPELVAERGGTAVRSRVGHSYIKALMAE
TGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALSEQDRPLSDFMADYQRYEASGEINFTVADAPACVEAVLKSFGTRI
HSIDHLDGVTVDLGGGQWFNLRTSNTEPLLRLNVEARTAEEVDEVVGQVSETVRAQNAEPGRTST

Sequences:

>Translated_465_residues
MSRPAAAVHRVIKAYDVRGLVGEELDEGFVADVGAAFARLVADGATQIVIGHDMRSSSPALSEAFAEGAMAQGLDVVRIG
LASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGAKPVGRDTGLAQIAEQVIDGVPAHDGPRGSASDRDVLTDYG
AFLRSLVEIPGRRPLRVAVDAGNGMAGHTTPAVLGPIEAITLLPLFFELDGTFPNHEANPLDPANLIDLQAHVVAVGADI
GLAFDGDADRCFVVDEKGQAVSPSAVTALVAARELGREIGATVIHNLITSRAVPELVAERGGTAVRSRVGHSYIKALMAE
TGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALSEQDRPLSDFMADYQRYEASGEINFTVADAPACVEAVLKSFGTRI
HSIDHLDGVTVDLGGGQWFNLRTSNTEPLLRLNVEARTAEEVDEVVGQVSETVRAQNAEPGRTST
>Mature_464_residues
SRPAAAVHRVIKAYDVRGLVGEELDEGFVADVGAAFARLVADGATQIVIGHDMRSSSPALSEAFAEGAMAQGLDVVRIGL
ASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGAKPVGRDTGLAQIAEQVIDGVPAHDGPRGSASDRDVLTDYGA
FLRSLVEIPGRRPLRVAVDAGNGMAGHTTPAVLGPIEAITLLPLFFELDGTFPNHEANPLDPANLIDLQAHVVAVGADIG
LAFDGDADRCFVVDEKGQAVSPSAVTALVAARELGREIGATVIHNLITSRAVPELVAERGGTAVRSRVGHSYIKALMAET
GAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALSEQDRPLSDFMADYQRYEASGEINFTVADAPACVEAVLKSFGTRIH
SIDHLDGVTVDLGGGQWFNLRTSNTEPLLRLNVEARTAEEVDEVVGQVSETVRAQNAEPGRTST

Specific function: Involved in xanthan production [H]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Escherichia coli, GI1788361, Length=436, Percent_Identity=38.5321100917431, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI1789566, Length=450, Percent_Identity=27.3333333333333, Blast_Score=110, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2; =5.4.2.8 [H]

Molecular weight: Translated: 48975; Mature: 48843

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPAAAVHRVIKAYDVRGLVGEELDEGFVADVGAAFARLVADGATQIVIGHDMRSSSPA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCH
LSEAFAEGAMAQGLDVVRIGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGA
HHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCCCEEECCCCCCHHCHHHHHHCCC
KPVGRDTGLAQIAEQVIDGVPAHDGPRGSASDRDVLTDYGAFLRSLVEIPGRRPLRVAVD
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
AGNGMAGHTTPAVLGPIEAITLLPLFFELDGTFPNHEANPLDPANLIDLQAHVVAVGADI
CCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHEEEEEEEECCE
GLAFDGDADRCFVVDEKGQAVSPSAVTALVAARELGREIGATVIHNLITSRAVPELVAER
EEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGTAVRSRVGHSYIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALSEQDR
CCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEHHHCCCCCHHHHHHHHHHHHCCCCC
PLSDFMADYQRYEASGEINFTVADAPACVEAVLKSFGTRIHSIDHLDGVTVDLGGGQWFN
CHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHCCCCEEEECCCCEEEE
LRTSNTEPLLRLNVEARTAEEVDEVVGQVSETVRAQNAEPGRTST
EECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SRPAAAVHRVIKAYDVRGLVGEELDEGFVADVGAAFARLVADGATQIVIGHDMRSSSPA
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCH
LSEAFAEGAMAQGLDVVRIGLASTDQLYFASGLLDCPGAMFTASHNPAAYNGIKLCRAGA
HHHHHHHHHHHCCCCEEEEECCCCCCHHHHCCCCCCCCCEEECCCCCCHHCHHHHHHCCC
KPVGRDTGLAQIAEQVIDGVPAHDGPRGSASDRDVLTDYGAFLRSLVEIPGRRPLRVAVD
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEE
AGNGMAGHTTPAVLGPIEAITLLPLFFELDGTFPNHEANPLDPANLIDLQAHVVAVGADI
CCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCHHHHHEEEEEEEECCE
GLAFDGDADRCFVVDEKGQAVSPSAVTALVAARELGREIGATVIHNLITSRAVPELVAER
EEEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGTAVRSRVGHSYIKALMAETGAIFGGEHSAHYYFRDFWGADSGMLAALHVLAALSEQDR
CCHHHHHHHHHHHHHHHHHHHCCEECCCCCCCEEEHHHCCCCCHHHHHHHHHHHHCCCCC
PLSDFMADYQRYEASGEINFTVADAPACVEAVLKSFGTRIHSIDHLDGVTVDLGGGQWFN
CHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCHHHHHHHCCCCEEEECCCCEEEE
LRTSNTEPLLRLNVEARTAEEVDEVVGQVSETVRAQNAEPGRTST
EECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280 [H]