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The map label for this gene is ygjG [C]

Identifier: 119867285

GI number: 119867285

Start: 1321753

End: 1323138

Strand: Reverse

Name: ygjG [C]

Synonym: Mkms_1235

Alternate gene names: 119867285

Gene position: 1323138-1321753 (Counterclockwise)

Preceding gene: 119867286

Following gene: 119867284

Centisome position: 23.06

GC content: 66.88

Gene sequence:

>1386_bases
ATGACGCAGTCCTATATCACCGAGCCCGTCACGAGCGAACTCGGGGCGAAAGCCAACCGGCACCTGTGGGGGCATTTCGC
CCGCCACGGCGAAGGCATCACCCCGCCGATCATCACCCGCGGCGAGGGCGTGCGCATCTGGGATGACAAGGGCCGCAGCT
ACATCGACGGACTGTCCGGGTTGTTCGTCGTCCAGGTCGGCCACGGCCGCAAGGAACTCGCCGAGGCCGCGGCCAAACAG
GCCGAGACGCTGTCGTTCTTCCCGCTGTGGTCCTACGCCACCCCGCCCGCGATCGAACTCGCCGAGCGCATCGCCAATTA
CGCACCCGGCGACCTGAACCGCGTGTTCTTCACCACCGGTGGCGGCGAGGCGGTCGAGAGCGCGTGGAAGCTGGCCAAGC
AATACTTCAAGCTGACCGGGAAACCCGGTAAGCACAAGGTGGTTTCGCGCGCGATCGCCTATCACGGCACCCCGCAAGGC
GCCTTGGCGATCACGGGCATCCCGGCGTTCAAGGCGCCGTTCGAACCGCTCACCCCCGGTGGGTTCCGCGCGCCGAACAC
GAACTTCTACCGTGCGCCGGAACCGTATGCGCACGACGTCAAGGCATTCGGGCAGTACTGCGCGGACCGCATCGCCGAGG
CCATCGAGTTCGAGGGGCCCGACACCGTTGCGGCCGTCTTCCTCGAGCCGGTACAGAACGCGGGTGGCTGTTTCCCGCCT
CCCCCAGGCTATTTCGAGCGGGTCCGCGAGATCTGCGACGAGTACGACGTGTTGCTGGTGTCCGACGAGGTGATCTGCGC
CTACGGCCGCATCGGGTCGATGTTCGCCTGCGACGACTTCGGTTACGTGCCGGACATCATCACCAGCGCCAAGGGTCTGA
CCTCGGGCTACTCCCCGCTCGGCGCGATGATCGCCAGCGACCGGCTGTTCGAACCGTTCAACGACGGTAAGACGACCTTC
GGGCACGGCTACACCTTCGGCGGGCATCCGGTGTCGGCGGCGGTGGCGCTGGCCAACCTCGACATCTTCGAGCGCGAAGG
CCTCAACGACCACGTCAAGGAGAACGCCCCGGCGTTCCGGGCGACGCTGGAGAAGCTCTACGACCTGCCGATCGTCGGCG
ACGTCCGCGGCGAGGGCTTCTTCTACGGCATCGAACTGGTCAAGGACAAGGCCACCAAGGAGACCTTCGACGACGACGAG
TCGGAGCGGCTGCTGCGCGGGTTCCTGACCCCTGCCCTGTGGGAGGCCGGACTGTACTGCCGCGCCGATGACCGTGGCGA
CCCAGTGGTGCAGCTGGCGCCGCCACTGATCAGCGGCCAGGCCGAGTTCGATGCGATCTACGAGATCCTGCACGGCGTGC
TCAGCGAGGCCGCGCGCCGGCTCTGA

Upstream 100 bases:

>100_bases
ACCTGTTGAACACGAAGATCCGCGCGCTGCCGGGAGTGGTATCCACGGAGACGTTGGTATATCTCAAACTGGTTAAGCAG
CAATATAATTGGGGAACACG

Downstream 100 bases:

>100_bases
CGTTCTTGCGCCGAGGCTGCTGGGAGATCGCCGTTTCGCGCAATACCGTGATCTGGCAGCAGGCTCGGCGCATCGCCGCG
TAGCGTCGGCGACGTGGCCT

Product: hypothetical protein

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MTQSYITEPVTSELGAKANRHLWGHFARHGEGITPPIITRGEGVRIWDDKGRSYIDGLSGLFVVQVGHGRKELAEAAAKQ
AETLSFFPLWSYATPPAIELAERIANYAPGDLNRVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVVSRAIAYHGTPQG
ALAITGIPAFKAPFEPLTPGGFRAPNTNFYRAPEPYAHDVKAFGQYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPP
PPGYFERVREICDEYDVLLVSDEVICAYGRIGSMFACDDFGYVPDIITSAKGLTSGYSPLGAMIASDRLFEPFNDGKTTF
GHGYTFGGHPVSAAVALANLDIFEREGLNDHVKENAPAFRATLEKLYDLPIVGDVRGEGFFYGIELVKDKATKETFDDDE
SERLLRGFLTPALWEAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYEILHGVLSEAARRL

Sequences:

>Translated_461_residues
MTQSYITEPVTSELGAKANRHLWGHFARHGEGITPPIITRGEGVRIWDDKGRSYIDGLSGLFVVQVGHGRKELAEAAAKQ
AETLSFFPLWSYATPPAIELAERIANYAPGDLNRVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVVSRAIAYHGTPQG
ALAITGIPAFKAPFEPLTPGGFRAPNTNFYRAPEPYAHDVKAFGQYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPP
PPGYFERVREICDEYDVLLVSDEVICAYGRIGSMFACDDFGYVPDIITSAKGLTSGYSPLGAMIASDRLFEPFNDGKTTF
GHGYTFGGHPVSAAVALANLDIFEREGLNDHVKENAPAFRATLEKLYDLPIVGDVRGEGFFYGIELVKDKATKETFDDDE
SERLLRGFLTPALWEAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYEILHGVLSEAARRL
>Mature_460_residues
TQSYITEPVTSELGAKANRHLWGHFARHGEGITPPIITRGEGVRIWDDKGRSYIDGLSGLFVVQVGHGRKELAEAAAKQA
ETLSFFPLWSYATPPAIELAERIANYAPGDLNRVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVVSRAIAYHGTPQGA
LAITGIPAFKAPFEPLTPGGFRAPNTNFYRAPEPYAHDVKAFGQYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPP
PGYFERVREICDEYDVLLVSDEVICAYGRIGSMFACDDFGYVPDIITSAKGLTSGYSPLGAMIASDRLFEPFNDGKTTFG
HGYTFGGHPVSAAVALANLDIFEREGLNDHVKENAPAFRATLEKLYDLPIVGDVRGEGFFYGIELVKDKATKETFDDDES
ERLLRGFLTPALWEAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYEILHGVLSEAARRL

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI24119277, Length=443, Percent_Identity=28.8939051918736, Blast_Score=153, Evalue=3e-37,
Organism=Homo sapiens, GI37574042, Length=429, Percent_Identity=28.6713286713287, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI4557809, Length=433, Percent_Identity=28.4064665127021, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI13994255, Length=447, Percent_Identity=25.7270693512304, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI226442705, Length=429, Percent_Identity=28.4382284382284, Blast_Score=142, Evalue=6e-34,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=28.643216080402, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI284507298, Length=336, Percent_Identity=29.4642857142857, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI145693181, Length=351, Percent_Identity=35.8974358974359, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI1789759, Length=417, Percent_Identity=31.1750599520384, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI1789016, Length=366, Percent_Identity=32.5136612021858, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788044, Length=372, Percent_Identity=31.1827956989247, Blast_Score=161, Evalue=8e-41,
Organism=Escherichia coli, GI1786991, Length=373, Percent_Identity=28.9544235924933, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787560, Length=426, Percent_Identity=30.2816901408451, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786349, Length=417, Percent_Identity=26.1390887290168, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32564660, Length=444, Percent_Identity=28.8288288288288, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI25144271, Length=439, Percent_Identity=28.7015945330296, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=443, Percent_Identity=26.1851015801354, Blast_Score=131, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI25144274, Length=241, Percent_Identity=31.1203319502075, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17541228, Length=445, Percent_Identity=22.4719101123595, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324432, Length=364, Percent_Identity=28.5714285714286, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6323470, Length=444, Percent_Identity=26.8018018018018, Blast_Score=146, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324386, Length=381, Percent_Identity=27.2965879265092, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI161085790, Length=391, Percent_Identity=28.9002557544757, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28574759, Length=391, Percent_Identity=28.9002557544757, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356575, Length=445, Percent_Identity=28.0898876404494, Blast_Score=145, Evalue=8e-35,
Organism=Drosophila melanogaster, GI21357415, Length=433, Percent_Identity=26.7898383371824, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50286; Mature: 50155

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSYITEPVTSELGAKANRHLWGHFARHGEGITPPIITRGEGVRIWDDKGRSYIDGLSG
CCCCHHCCHHHHHHCCHHCHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCCHHHHCCCC
LFVVQVGHGRKELAEAAAKQAETLSFFPLWSYATPPAIELAERIANYAPGDLNRVFFTTG
EEEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
GGEAVESAWKLAKQYFKLTGKPGKHKVVSRAIAYHGTPQGALAITGIPAFKAPFEPLTPG
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCC
GFRAPNTNFYRAPEPYAHDVKAFGQYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
PPGYFERVREICDEYDVLLVSDEVICAYGRIGSMFACDDFGYVPDIITSAKGLTSGYSPL
CCCHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEECCCCCHHHHHHHHCCCCCCCCHH
GAMIASDRLFEPFNDGKTTFGHGYTFGGHPVSAAVALANLDIFEREGLNDHVKENAPAFR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHCCCCHHHHHCCHHHH
ATLEKLYDLPIVGDVRGEGFFYGIELVKDKATKETFDDDESERLLRGFLTPALWEAGLYC
HHHHHHHCCCCEECCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
RADDRGDPVVQLAPPLISGQAEFDAIYEILHGVLSEAARRL
EECCCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQSYITEPVTSELGAKANRHLWGHFARHGEGITPPIITRGEGVRIWDDKGRSYIDGLSG
CCCHHCCHHHHHHCCHHCHHHHHHHHHCCCCCCCCEEECCCCEEEECCCCCHHHHCCCC
LFVVQVGHGRKELAEAAAKQAETLSFFPLWSYATPPAIELAERIANYAPGDLNRVFFTTG
EEEEEECCCHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEECC
GGEAVESAWKLAKQYFKLTGKPGKHKVVSRAIAYHGTPQGALAITGIPAFKAPFEPLTPG
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCC
GFRAPNTNFYRAPEPYAHDVKAFGQYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCC
PPGYFERVREICDEYDVLLVSDEVICAYGRIGSMFACDDFGYVPDIITSAKGLTSGYSPL
CCCHHHHHHHHHCCCCEEEECCCEEEECCCCCCEEEECCCCCHHHHHHHHCCCCCCCCHH
GAMIASDRLFEPFNDGKTTFGHGYTFGGHPVSAAVALANLDIFEREGLNDHVKENAPAFR
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHCCCCHHHHHCCHHHH
ATLEKLYDLPIVGDVRGEGFFYGIELVKDKATKETFDDDESERLLRGFLTPALWEAGLYC
HHHHHHHCCCCEECCCCCCEEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEE
RADDRGDPVVQLAPPLISGQAEFDAIYEILHGVLSEAARRL
EECCCCCCEEEECCCHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]