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The map label for this gene is thcR [H]

Identifier: 119867267

GI number: 119867267

Start: 1301344

End: 1302300

Strand: Reverse

Name: thcR [H]

Synonym: Mkms_1217

Alternate gene names: 119867267

Gene position: 1302300-1301344 (Counterclockwise)

Preceding gene: 119867268

Following gene: 119867266

Centisome position: 22.7

GC content: 71.26

Gene sequence:

>957_bases
GTGGACACGCACACCGCGAGCCTCGTCCGCCGCGCCTCGTGGGCCACGCCCGACCTCGCCGAGGCGCACGACCTCCTGCA
CGCCGAGTACGGGGCCAGCCTGAGGCTGGGCGAATCGCGGGCTTCGGCCCGCCAGCTCAGCGTCGACCGTCGTCAGACCC
CCACCTTCGAATGCCACGACGTGCGGTTGCCCGCCCGCCTTCAGTTCGACGTCGAGGACTACGGCGGTGTGGTCATCGCC
GCCCTGCAGGCCGGCACGGTGACCGCGAACAGCGACGCCCACGGCGTCTCGTACCGGCGGGGTGACGTGTTCATGTCGAA
CTTCCCCGGCGCGCACTACCGCTGCCACACCGACCACGCCTGGTCGCACACCGTCACCATCCCGGTGCGGGTGCTTGCCG
AATCCGCCGGTGTCCCGCCGTCGTCGCTGCGGTTCATGTCGGGCAACCCGGTCAGCGCCGACGCCGCCGCGAAGTGGGTG
GCCACGCTCGAGACCGTGGAGCGGTTGCTCGACGACCCGGACACCGCCAACCCGATCGTGCTCGGCAAGGCCGGCCGCAT
GCTGGCCGCCCGAGTGCTCGAGATCTTCCCCGTGACCAGGACACCCGGGACGGAACACCCGGGCCGGCTGGTGCCCAACT
TCCTCCGAAGGGCGATCGCCTACATGGAGGACAACGCCACCGCGGACATCGGCGTCGCCGACATCGCCGCCGCGGTCGAG
CTCACCCCCGACGGCGTGACCTACCTGTTCCGGCGTCACCTCGGGGTGGGCCCGCTCGATCACCTGCGTCGCATCCGGCT
CGACCACGCCCACCGGGACCTGCTCGACCACGACCCCGAGTCGACGACGGTGTTCTCCATCGCGGCCCGCTGGGTGTTCC
CGCACCTGCCGTCGTTCGAGGAGCTCTACTGCGGCTCCTACGGCCAGAATCCGCGGGACACGCTGCAGGCCGGCTGA

Upstream 100 bases:

>100_bases
AAGTTTCGGCAAATATTCGTGTCCTCGCCATGAGTACAGTTATGGTTTCCCTGAGCGCGGCTGACCTGTTGATCCGACGG
CCACCGCGGAAGGGGGCCGA

Downstream 100 bases:

>100_bases
CCGGTAGATTCGCAAGGTGGCACGCGCCTTCGGAGTGGTCGGACGCTATCTGGCCGGCGCGCCGGCGACCTTCATGTGGC
TGGCCGTCCTCGCCGTCACC

Product: helix-turn-helix domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MDTHTASLVRRASWATPDLAEAHDLLHAEYGASLRLGESRASARQLSVDRRQTPTFECHDVRLPARLQFDVEDYGGVVIA
ALQAGTVTANSDAHGVSYRRGDVFMSNFPGAHYRCHTDHAWSHTVTIPVRVLAESAGVPPSSLRFMSGNPVSADAAAKWV
ATLETVERLLDDPDTANPIVLGKAGRMLAARVLEIFPVTRTPGTEHPGRLVPNFLRRAIAYMEDNATADIGVADIAAAVE
LTPDGVTYLFRRHLGVGPLDHLRRIRLDHAHRDLLDHDPESTTVFSIAARWVFPHLPSFEELYCGSYGQNPRDTLQAG

Sequences:

>Translated_318_residues
MDTHTASLVRRASWATPDLAEAHDLLHAEYGASLRLGESRASARQLSVDRRQTPTFECHDVRLPARLQFDVEDYGGVVIA
ALQAGTVTANSDAHGVSYRRGDVFMSNFPGAHYRCHTDHAWSHTVTIPVRVLAESAGVPPSSLRFMSGNPVSADAAAKWV
ATLETVERLLDDPDTANPIVLGKAGRMLAARVLEIFPVTRTPGTEHPGRLVPNFLRRAIAYMEDNATADIGVADIAAAVE
LTPDGVTYLFRRHLGVGPLDHLRRIRLDHAHRDLLDHDPESTTVFSIAARWVFPHLPSFEELYCGSYGQNPRDTLQAG
>Mature_318_residues
MDTHTASLVRRASWATPDLAEAHDLLHAEYGASLRLGESRASARQLSVDRRQTPTFECHDVRLPARLQFDVEDYGGVVIA
ALQAGTVTANSDAHGVSYRRGDVFMSNFPGAHYRCHTDHAWSHTVTIPVRVLAESAGVPPSSLRFMSGNPVSADAAAKWV
ATLETVERLLDDPDTANPIVLGKAGRMLAARVLEIFPVTRTPGTEHPGRLVPNFLRRAIAYMEDNATADIGVADIAAAVE
LTPDGVTYLFRRHLGVGPLDHLRRIRLDHAHRDLLDHDPESTTVFSIAARWVFPHLPSFEELYCGSYGQNPRDTLQAG

Specific function: Probably involved in the positive regulation of the thc operon for the degradation of the thiocarbamate herbicide EPTC [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34866; Mature: 34866

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTHTASLVRRASWATPDLAEAHDLLHAEYGASLRLGESRASARQLSVDRRQTPTFECHD
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHCCCCCCCCCCEEEC
VRLPARLQFDVEDYGGVVIAALQAGTVTANSDAHGVSYRRGDVFMSNFPGAHYRCHTDHA
CCCCCEEEECHHHCCCEEEEEEECCEEEECCCCCCCEEECCCEEEECCCCCCEEECCCCC
WSHTVTIPVRVLAESAGVPPSSLRFMSGNPVSADAAAKWVATLETVERLLDDPDTANPIV
CCEEEEEHHHHHHHHCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LGKAGRMLAARVLEIFPVTRTPGTEHPGRLVPNFLRRAIAYMEDNATADIGVADIAAAVE
ECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEE
LTPDGVTYLFRRHLGVGPLDHLRRIRLDHAHRDLLDHDPESTTVFSIAARWVFPHLPSFE
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCHH
ELYCGSYGQNPRDTLQAG
HHHCCCCCCCHHHHCCCC
>Mature Secondary Structure
MDTHTASLVRRASWATPDLAEAHDLLHAEYGASLRLGESRASARQLSVDRRQTPTFECHD
CCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCHHHHHHHHCCCCCCCCCCEEEC
VRLPARLQFDVEDYGGVVIAALQAGTVTANSDAHGVSYRRGDVFMSNFPGAHYRCHTDHA
CCCCCEEEECHHHCCCEEEEEEECCEEEECCCCCCCEEECCCEEEECCCCCCEEECCCCC
WSHTVTIPVRVLAESAGVPPSSLRFMSGNPVSADAAAKWVATLETVERLLDDPDTANPIV
CCEEEEEHHHHHHHHCCCCHHHEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEE
LGKAGRMLAARVLEIFPVTRTPGTEHPGRLVPNFLRRAIAYMEDNATADIGVADIAAAVE
ECCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHEEEE
LTPDGVTYLFRRHLGVGPLDHLRRIRLDHAHRDLLDHDPESTTVFSIAARWVFPHLPSFE
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHCCCCCHH
ELYCGSYGQNPRDTLQAG
HHHCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7836301 [H]